석회비종이 (石灰肥種) 대두의 (大豆) 생육 및 수량에 미치는 영향

김희권,전장협,정지호,박건호 ( H . W . Kim,J . H . Jeon,C . H . Chung,K . H . Park ) 한국토양비료학회 1988 한국토양비료학회 학술발표회 Vol.1988 No.41

고유수용성신경근촉진법의 팔 폄 패턴이 반대편 다리의 근활성도에 미치는 영향

김희권,김건,최재원,정현애,Kim, Hee-Gwon,Kim, Gyeon,Choi, Jae-Won,Chung, Hyun-Ae 대한고유수용성신경근촉진법학회 2014 PNF and Movement Vol.12 No.1

Purpose: The purpose of this study is to analyze the effect of the arm extension pattern of proprioceptive exercise program on the muscle activity of the opposite lower extremity. Methods: In this study, electromyogram MP150(Biopac system, USA) was applied to 20 healthy male subjects. Arm extension-adduction-internal rotation pattern was applied within initial, mid and end range in sling position and supine position for measurement. And the effect on the activity of rectus femoris and tibialis anterior muscle of the opposite lower extremity was compared and analyzed. Results: The results of this study were summarized as follows: First, there was a statistically significant difference of the activity of the tibialis anterior muscle within the Initial range in sling position and supine position(P<0.05). Second, there was a statistically significant difference of the activity of the tibialis anterior muscle within the end range in sling position and supine position(P<0.05). Conclusion: Rectus femoris and tibialis anterior muscles shows the higher activity in the supine position than in the sling position. Therefore, the supine position is more appropriate than the sling position to make irradiation on lower extremity muscle with the extension pattern.

요부 굴곡운동과 요부 신전운동에 의한 요통예방 및 치료

김희권 목포대학교 스포츠 산업연구소 2004 스포츠 산업연구소 논문집 Vol.3 No.-

Low back pain is significant problem on today's society and economy with lifetime incidence rate reported between 70-80 percent. The purpose of this study is to present lumbar flexion exercise and lumbar extension exercise for recovering lumbar curve. The apply for the effectiveness which the lumbar flexion exercise is as follows ; 1. Strengthen the abdomen muscles and decrease the pressure which the lumbar facet joint comes to add. 2. Increase the flexibility through to stretch of the lumbar extension muscles. 3. Make broad intervertebral foremen interval and decrease the pressure of the nerve root. The apply for the effectiveness which the lumbar extension exercise is as follow 1. Strengthen the lumbar extension muscles and make the lumbar curve recover to the normal. 2. Decrease the pressure to add for intervertebral disc or posterior longitudinal ligament. 3. Increase the flexibility through to stretch of the lumbar flexion muscles.

국내 산악철도 건설사례

김희권,인성윤,안상용 한국철도학회 2015 철도저널 Vol.18 No.1

치료적 운동프로그램이 편마비 환자의정적⋅동적 균형 수행력에 미치는 영향

김희권 대한고유수용성신경근촉진법학회 2011 PNF and Movement Vol.9 No.4

Purpose: The purpose of this study was to analyze the effect of closed kinematic chain exercise and proprioceptive neuromuscular facilitation exercise on the static⋅dynamic balance performance of hemiplegic patients in order to suggest them therapeutic intervention methods. Methods: The subjects of this study were 18 hemiplegic patients grouped into 2 subgroups according to the exercise program. one group of closed kinematic chain exercise carried out sit to stand, Hooklying with pelvic lift(bridging) and stair-up & down by a hemiplegic leg. The other group of proprioceptive neuromuscular facilitation exercise carried out leg flexion-extension pattern in supine position, leg flexion pattern in standing and stabilizing reversal exercise in stating position. Each exercise was carried out over 3 sets of 10reps. Results: The results of this study were summarized as follows: 1. For both groups, there were statistically significant changes in the static balance (FICSIT-4) performance after exercise program (p<.05). 2. For both groups, there were statistically significant changes in the dynamic balance (FSST, TUG, FRT) performance after exercise program (p<.05). 3. In the comparison between both groups, there was no statistically significant difference in the static⋅dynamic balance performance (FICSIT-4, FSST, TUGT, ER) after exercise program. Conclusion: As the results of the study shows closed kinematic chain exercise and proprioceptive neuromuscular facilitation exercise affect the improvement of hemiplegic patients’' static⋅dynamic balance performance, it is supposed that these exercises could be therapeutic exercise program in clinical situations. .

Hutchinson–Gilford Progeria Syndrome with G608G LMNA Mutation

김희권,이종윤,배은주,오필수,박원일,이동성,김종일,이홍진,김성진,윤숙정 대한의학회 2011 Journal of Korean medical science Vol.26 No.12

Hutchinson–Gilford progeria syndrome (HGPS) is a rare condition originally described by Hutchinson in 1886. Death result from cardiac complications in the majority of cases and usually occurs at average age of thirteen years. A 4-yr old boy had typical clinical findings such as short stature, craniofacial disproportion, alopecia, prominent scalp veins and sclerodermatous skin. This abnormal appearance began at age of 1 yr. On serological and hormonal evaluation, all values are within normal range. He was neurologically intact with motor and mental development. An echocardiogram showed calcification of aortic and mitral valves. Hypertrophy of internal layer at internal carotid artery suggesting atherosclerosis was found by carotid doppler sonography. He is on low dose aspirin to prevent thromboembolic episodes and on regular follow up. Gene study showed typical G608G (GGC- > GGT) point mutation at exon 11 in LMNA gene. This is a rare case of Hutchinson-Gilford progeria syndrome confirmed by genetic analysis in Korea.

고유수용성신경근촉진법 팔⋅다리 굽힘패턴이 반대측 다리의 근활성도에 미치는 영향

김희권,김건 대한고유수용성신경근촉진법학회 2014 PNF and Movement Vol.12 No.3

Purpose: The purpose of this study is to analyze the effect of arm⋅leg flexion patterns of proprioceptive neuromuscular facilitation on the muscle activation of the contralateral lower extremity. Methods: In this study, Electromyogram MP150(Biopac system, USA) was applied to 20 healthy male subjects. Unilateral arm flexion- abduction- external rotation pattern and Unilateral leg flexion- adduction- external rotation with knee flexion pattern were applied within mid range of the supine position for measurement. The muscle activation of vastus lateralis, biceps femoris, tibialis anterior and gastrocnemius(medialis) muscle of the contralateral lower extremity were compared and analyzed during the applications. Results: The results of this study were summarized as follows: There was a statistically significant difference in the muscle activation of vastus lateralis and biceps femoris between the arm and leg patterns(P<0.05). There was a statistically significant difference in the muscle activation of gastrocnemius and tibialis anterior between the arm and leg patterns(P<0.05). Conclusion: contralateral vastus lateralis, biceps femoris, gastrocnemius and tibialis anterior muscles show the higher muscle activation in the leg pattern than one in the arm pattern. .

한국인 소아청소년기 발작의 원인질환으로서의 유기산대사이상질환

김희권,이종윤,이예승,배은주,오필수,박원일,이홍진,Kim, Hui Kwon,Lee, Jong Yoon,Lee, Ye Seung,Bae, Eun Joo,Oh, Phil Soo,Park, Won Il,Lee, Hong Jin 대한유전성대사질환학회 2012 대한유전성대사질환학회지 Vol.12 No.1

목적: 발작은 소아기에 상당히 흔한 임상 증상으로 급성증상성발작은 대뇌의 구조적변화, 염증, 및 대사이상 등이 원인이 될 수 있다. 대사이상을 일으킬 수 있는 대사장애 질환들로는 유기산대사이상질환군, 리소솜축적질환군, 퍼옥시솜대사이상질환군, 미량원소의 이상질환군 등이 있다. 저자들은 발작을 일으키는 유기산대사이상 질환들의 중요성을 알아보기 위하여 본 연구를 시행하였다. 방법: 2007년 1월1일부터 2011년 12월 31일까지 만 5년 동안 유기산분석이 의뢰되었던 1,306명의 환자를 2개월까지의 신생아기, 2세까지의 영아기, 12세까지의 소아기 및 12세 이후의 청소년기이후의 4군으로 나누고, 발작의 형태는 전신발작, 국소발작 및 복합발작으로 나눴으며, 발달지연의 유무에 따라 SPSS의 student's t test를 이용하여 후향적으로 분석하였다. 결과: 전체적으로 1,306명의 환자에서 유기산분석에서 비정상소견을 보인 경우가 665명(51%)이었으며, MRCD가 394명(30.1%), mandelic aciduria가 127명(9.7%), 케톤분해이상이 81명(6.2%), 3-hydroxyisobutyric aciduria가 19명(1.4%), glutaric aciduria type II가 10명(0.8%) 이었고 뒤를 이어 ethylmalonic aciduria 4명, propionic aciduria 4명이었으며, 3명의 환자가 진단된 질환들이 methylmalonic aciduria, glutaric aciduria type I, pyruvate dehydrogenase deficiency, pyruvate carboxylase deficiency 등이 있었으며, 2례씩 진단된 질환들이 isovaleric aciduria, HMG-CoA lyase deficiency, 3-methylcrotonylglycinuria, fatty acid oxidation disorders 등이 있었고, 1례씩 진단된 질환들로 fumaric aciduria, citrullinemia, CPS deficiency, MCAD deficiency 등이 있었다. 결론: 신생아기에는 감염으로 인한 mandelic aciduriad의 빈도가 의미 있게 높았고, 전연령군에서 MRCD의 중요성이 큰 것으로 파악되었다. 신생아기이후에도 다양한 유기산대사이상들의 진단이 되고 있어 기본검사의 중요성이 높았으며, 증상이 있을 때의 초기검체를 이용한 검사가 중요하다고 판단되었다. Purpose: Acute symptomatic seizures are caused by structural changes, inflammation or metabolic changes of brain, such as tumor, stroke, meningitis, encephalitis and metabolic disorders. Inherited metabolic disorders that can cause seizures are organic acidopathies, lysosomal storage disorders, peroxisomal disorders and mineral disorders. We have done this study to find out the importance of organic acidopathies causing seizure disorders in Korean childhood and adolescent patients. Method: Retrograde analysis for 1,306 patients with seizure disorders whose clinical informations are available and have done urine organic acid analysis for 5 years period, between Jan. 1st 2007 to Dec. 31th 2011. Statistical analysis was done with Student's t test using SPSS. Result: Out of 1,306 patients, 665 patients (51%) showed abnormalities on urine organic acid analysis. The most frequent disease was mitochondrial respiratory chain disorders (394, 30.1%), followed by mandelic aciduria (127, 9.7%), ketolytic defects (81, 6.2%), 3-hydroxyisobutyric aciduria (19, 1.4%), glutaric aciduria type II (10, 0.8%), ethylmalonic aciduria (4), propionic aciduria (4), methylmalonic aciduria (3), glutaric aciduria type I (3), pyruvate dehydrogenase deficiency (3), pyruvate carboxylase deficiency (3), isovaleric aciduria (2), HMG-CoA lyase deficiency (2), 3-methylcrotonylglycinuria (2), fatty acid oxidation disorders (2), fumaric aciduria (1), citrullinemia (1), CPS deficiency (1), MCAD deficiency (1). Conclusion: On neonatal period, mandelic aciduria due to infection was found relatively frequently. Mitochondrial disorders are most frequent etiologic disease on all age group, followed by ketolytic defects and various organic acidopathies. The number and diversities of organic acidopathies emphasize meticulous evaluation of basic routine laboratory examinations and organic acid analysis with initial sample on every seizure patient.

Development of radiolabeled somatostatin derivatives for neuroendocrine tumors

김희권 대한방사성의약품학회 2021 Journal of radiopharmaceuticals and molecular prob Vol.7 No.2

Neuroendocrine tumor is one of popular diseases, and somatostatin receptor antagonists have been considered as promising agents for neuroendocrine tumors. Imaging of somatostatin receptor is useful approach on the diagnosis and therapy of neuroendocrine tumors. Thus, several radiolabeled somatostatin derivatives have been developed by scientists, and used for patients with neuroendocrine tumors. In particular, some radiopharmaceuticals for neuroendocrine tumors were approved by FDA. In this highlight review, the development of important radiolabeled somatostatin derivatives is described.

건설업 무인 시공 로봇 위험성평가 연구

김희권,전진우,임동언,박교식 한국재난정보학회 2023 한국재난정보학회 학술대회 Vol.2023 No.11

현대에 이르러서 기술의 발전과 COVID-19 확산, 인구 고령화, 3D 업종 기피 등의 영향으로 부족한 노동력을 대체하고 비대 면 업종 증가에 따라 이동성을 갖춘 서비스 로봇이 대거 개발 및 보급되고 있다. 서비스 로봇의 시장 진입을 촉진하기 위한 움직 임을 활발히 있으나 이에 관한 체계적인 사고조사 및 안전연구가 이루어지지 않는 상황이다. 본 논문에서는 전문 서비스 로봇의 안전한 사용을 위하여 서비스 로봇의 설치 및 사용 단계에서의 위험성평가 모델 개발과 건설업 무인 시공 로봇의 위험성 평가 과정을 기술한다.