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김은서,김영철,김석천,홍석찬,Kim Eun-Seo,Kim Young-Chul,Kim Sok-Chon,Hong Seok-Chan 대한두경부종양학회 2000 대한두경부 종양학회지 Vol.16 No.2
It is difficult to find the penetrating foreign bodies in the head and neck area only with history taking and physical examinations. One of the most important things is to detect the precise location of foreign bodies or possibly remained materials. The detection of wooden foreign bodies is important because they can cause phlegmon formation and because wood is often contaminated by Clostridium tetani bacteria. CT has proved to be an expedient method for detecting foreign bodies of various materials in soft tissues, but the wooden foreign body is often misinterpreted as a gas bubble in soft tissue. We have experienced a case of wooden foreign body which has penetrated through nasal dorsum and remained for 4 months. It had been initially misinterpreted as longstanding inflammatory lesion and osteitis of maxilla and nasal bone.
김은서,이용희,심정연,유영석,Kim Eun-Seo,Lee Yong-Hee,Shim Jeong-Yun,Yoo Yeong-Seok 대한두경부종양학회 2000 대한두경부 종양학회지 Vol.16 No.2
Mucosal melanoma of the head and neck is a rare and usually lethal disease. Primary laryngeal malignant melanoma(LMM) are exceedingly rare tumors that morphologically are readily confused with more common types of laryngeal cancer. Treatment of choice for LMM is complete surgical excision and elective lymph node dissection is usually not recommended. The use of radiation or chemotherapy is generally thought to have no effect on local or distant disease and currently used as adjuvant therapy. The prognosis is extremely poor. We have experienced a 61 year old male patient with symptoms of foreign body and lump sense in throat. A dark pigmented polypoid mass was found on the right aryepiglottic folds with normal mobility of vocal cord. Total laryngectomy was performed under the diagnosis of malignant melanoma. Bone scan revealed multiple bony metastasis on ribs and lumbar vertebrae after 5 months of operation. There have been no evidence of recurrence at primary area. The patient died after 8 months of operation.
범혈구감소증을 동반한 간경변 환자의 소화불량 증례 보고
김은서,배인숙,신길조,Kim, Eun-seo,Bae, In-suk,Shin, Gil-cho 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.5
Objectives: The purpose of this study was to report the improvement of dyspepsia in a patient with liver cirrhosis and pancytopenia following traditional Korean medical treatment. Methods: A patient who suffered from dyspepsia with liver cirrhosis and pancytopenia was treated with herbal medicine, acupuncture, cupping, and moxibustion. The effect of treatment was measured with a visual analogue scale (VAS). Results: After treatment, the symptoms of dyspepsia improved and VAS score decreased. Conclusions: Traditional Korean medicine (TKM) could be effective for treatment of dyspepsia in patients with liver cirrhosis.
김은서,손종석,배인숙,서상일,신길조,Kim, Eun-seo,Son, Jong-seok,Bae, In-suk,Seo, Sang-il,Shin, Gil-cho 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.5
Objective: To report a case of a patient with a psychosomatic disorder who complained of hyperventilation and was treated with oriental medical treatments and emotional freedom techniques (EFTs). Methods: The patient was diagnosed as having a psychosomatic disorder through an interview and several psychological tests, such as the house-tree-person (HTP) and the person in the rain (PITR) tests. We treated the patient with oriental medical treatments that included herbal medications, western medications, moxibustion, cupping, and EFT. Results: After the treatments, the clinical symptoms of the patient were improved. Conclusions: Oriental medical treatments and EFT may be effective treatments for psychosomatic disorders.
오심, 구토, 복통으로 인해 급격한 체중감소를 보인 환자 치험 1례
김은서,손종석,신길조,Kim, Eun-seo,Son, Jong-seok,Shin, Gil-cho 대한중풍순환신경학회 2015 대한중풍.순환신경학회지 Vol.16 No.1
This patient was 18 year-old man who had severe nausea, vomiting, stomachache but medical examination revealed no abnormality. The symptom lasted for 2 months and he lost 15kilograms. The patient had no underlying diseases. He was treated by korean medicine, containing acupuncture, cupping therapy and herb medicines during 9 days. The severity of nausea was scored by the Numerous Rating Scale and the frequency of vomitng was evaluated by count. After that period, patient's symptom was improved and his other conditions were also better, compared with his admission. This study suggests that Korean medicine could have a therapeutic effect for nausea, vomiting, stomachache and rapid weight loss that the cause has not been diagnosed by Western medicine. It could help to improve patient's symptoms and make general conditions better.
글루타메이트에 의해 산화적 스트레스를 받은 HT22 세포에서 핑거루트의 신경세포 보호활성
김은서,마충제,Kim, Eun Seo,Ma, Choong Je 한국생약학회 2022 생약학회지 Vol.53 No.2
Excessive glutamate causes oxidative stress in neuronal cells, which can cause degenerative neurological disorders. We tried to find medicinal plant showed neuroprotective activity by using glutamate-injured HT22 cell as a model system. In this study, we found that Boesenbergia rotunda methanol extract showed neuroprotective activity against glutamate induced neurotoxicity in mouse hippocampal HT22 cells. B. rotunda methanol extract suppressed the formation of reactive oxygen species and decreased intracellular Ca<sup>2+</sup>concentration. Also, B. rotunda made mitochondrial membrane potential maintain to normal levels. In addition, B. rotunda increased total glutathione amount and activated antioxidative enzyme such as glutathione reductase and glutathione peroxidase compared to glutamate-treated groups. These results suggested that B. rotunda decreased neuronal cell death damaged by high concentrations of glutamate treatment, via antioxidative mechanism and might be one of candidate of development of new drug to treat neurodegenerative disease such as Alzheimer's disease.