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- 저자 : 김용구(Kim, Younggu) (검색결과 575 건)
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김용구,이상열,김한나,노학재,봉춘근,김대성,Kim, Yonggu,Lee, Sangyul,Kim, Hannah,Noh, Hakjae,Bong, Choonkeun,Kim, Daesung 한국입자에어로졸학회 2015 Particle and Aerosol Research Vol.11 No.2
The purpose of this research is to find out the collection property of nanoparticle in diffusion filter to know particle size dispersion of nanomaterial using inertial force and principle of Brownian diffusion motion. We used inertial filters which are two different type and diffusion filters made by various kinds of Wiremesh and the different pieces of filter to compare with particle size distribution using NaCl particles. Finally, We made a conclusion as follows : (1) the bigger available charging volume is and the larger specific surface area of inertial filter is, the better collection efficiency is. (2) The higher wire-mesh number of filter is, the more collection efficiency of small particle is increasing because the wire of the higher Wiremesh number filter is thinner and denser. (3) The more pieces of wire-mesh filter, the more collection efficiency is increasing because it makes the residence time longer.
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정신분열증 환자에서 혈장 HVA 및 5-HIAA 농도와 정신병리와의 상관성
김용구,박성근,김인,이민수,Kim, Yong-Ku,Park, Sung-Geun,Kim, Leen,Lee, Min-Soo 대한생물정신의학회 1997 생물정신의학 Vol.4 No.1
The recent hypothesis about the pathophysiology of schizophrenia has been centered mainly on two theories, i.e. dopamine hypothesis and serotonin hypothesis. We investigate the correlations between plasma monoamine metabolite concentrations and clinical symptoms in schizophrenic patients. The first purpose of our study was to examine whether the plasma levels of HVA(homovanillic acid) and 5-HIAA(hydroxyindoleacetic acid) are significantly different in schizophrenics, compared to normal controls. And, with the intention of clarifying the interaction between dopaminergic system and serotoninergic system, the ratio of HVA/5-HIAA also was measured. The second purpose was whether the basal(pre-treatment) levels of these metabolites show the correlation with clinical symptoms. Finally, third purpose was whether basal HVA and 5-HIAA levels can be held as a predictor of treatment response. We used Scale for the Assessment of Positive Symptoms(SAPS) and Scale for the Assessment of Negative Symptoms(SANS) as the clinical symptom rating scales. Our results were as followed, 1) only the level of basal plasma HVA was significantly differ in schizophrenics. 5-HIAA and HVA/5-HIAA were not. 2) basal HVA showed significant correlation with SAPS score, especially delusion subscale. 3) the higher was the basal HVA level, the more improvement in clinical symptoms was observed. The basal 5-HIAA level and the HVA/5-HIAA ratio did not show any significant findings. These results support the dopamine hypothesis of schizophrenia, but fail to examine on the possible involvement of serotonin in schizophrenia.
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자살을 시도한 주요우울증 환자에서 혈청 콜레스테롤 농도의 저하
김용구,이헌정,곽동일,Kim, Yong Ku,Lee, Heon Jeong,Kwak, Dong II 대한생물정신의학회 1996 생물정신의학 Vol.3 No.2
Objective : Several studies hove suggested that reduction of cholesterol concentration and low cholesterol level increases suicide, homicide, and depression. The authors sought to determine whether low cholesterol is associated with a history of suicidal attempts among major depression patients. Method : The subjects were 105 patients with major depression, diagnosed according to the DSM-III-R criteria, and 105 age, sex matched healthy controls. Blood was token following overnight fast and serum cholesterol concentration were measured by a enzymatic method Results : The serum cholesterol level was significantly lower in the patients with major depression than in healthy controls($180.4{\pm}43.4mg/dl$ vs $199.7{\pm}35.8mg/dl$). And the serum cholesterol level was significantly lower in major depression patients with suicidal attempt than in major depression patients without suicidal attempt($156.7{\pm}38.2mg/dl$ vs $ 187.8{\pm}42.5mg/dl$) Conclusion : It is hypothesized that low cholesterol level is associated with depression by modifying the serotonin metabolism and the production of interleukin-2, low cholesterol concentration should be further investigated as a potential biological marker of suicidal risk in major depression. Prospective study with serial cholesterol determinations should be done.
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국내 건설환경 변화에 따른 수주조직구조 설계에 관한 연구
김용구,김선국,Kim Yong-Gu,Kim Sun-Kuk 한국건설관리학회 2005 건설관리 : 한국건설관리학회 학회지 Vol.6 No.3
최근 급속한 국내 건설환경의 변화속에서 기업은 구조개성을 포함한 다양한 변화를 추구하고 있으나, 이러한 노력이 경영 이익 증대까지 이어지지 못하고 있는 실정이다. 이러한 현상의 주요 원인 중 하나는 수주와 관련된 내 $\cdot$ 외부 환경변화를 기업의 경영전략과 조직구조에 반영하여 변화에 적응하고 더불어 수주성과를 극대화하기 위한 다양한 변화노력의 틀 속에서 진행되어야 함에도 불구하고 이와 같은 접근이 이루어지지 못하고 있기 때문이다. 특히 급변하는 환경에서 기업의 경영이익을 좌우하는 수주활동과 관련된 조직의 설계는 전반적 인 건설경기동향, 공공 및 민간의 발주 동향 등을 고려한 전략적이고 유연한 접근이 필요하다. 이에 본 연구에서는 수주환경 변화에 따른 수주조직을 전략적으로 설계할 수 있도록 환경변화와 경영성과측면의 관계를 규명하여 이를 대형건설업체의 사업유형 및 발주유형별 수주조직 설계에 반영할 수 있도록 모형과 절차를 제시하였다. Recently, many Korean construction companies have tried to modify organization structures in order to increase the performance profit while coping with environmental changes in the construction market. Most Korean construction companies are adapting to environmental changes and devote various struggle for maximizing the result of receiving order. Especially, the organization structure of Marketing Divisions is the important for management performance and is the important key elements to attain the management goals. This research on construction companies organization has never been dealt before in korea. Through this research, the relationship between construction environmental changes and management performance profit is proven and is reflected when making the Marketing Divisions. It suggests the Marketing Divisions structure model by business type and receiving order type. Also, the result of this research could be used the important basic data that is necessary to the organization model development and this model development can be prepared for facing the new environmental changes in the near future.
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정신분열병 환자에서 인지기능 및 정신병적 증상의 상관관계
김용구,이정애,이소연,이분희,한창수,Kim, Yong-Ku,Lee, Jung-Ae,Lee, So-Youn,Lee, Bun-Hee,Han, Chang-Su 대한생물정신의학회 2006 생물정신의학 Vol.13 No.3
Objectives : The purpose of this study was to investigate whether the cognitive functions would be correlated with psychotic symptoms and whether antipsychotic treatments would affect the cognitive functions after 8 weeks. Methods : The thirty-five schizophrenic patients were conducted in this study. The psychopathology was measured using PANSS. The memory function, executive function, and sustained attention were measured using Memory Assessment Scale(MAS), Wisconsin Card Sorting Test(WCST), and Vigilance(VIG) and Cognitrone(COG) in Vienna Test System. After 8 weeks of antipsychotic treatment, we retested the cognitive tests. Results : 1) The cognitive tests after the 8 week's treatment showed significant improvements in memory and executive function in the schizophrenic patients. On the other side, sustained attention did not show improvement. 2) The change of PANSS were correlated with perseverative response, perseverative error and total correct in WCST at baseline. WCST scores at baseline were correlated with negative symptoms, but not positive ones. Conclusion : These study suggests that 1) the impaired sustained attention could be a vulnerability marker in schizophrenia, 2) memory & executive function deficit could be reversible after treatment, and 3) medication might have a benefit in improving the cognitive functions in schizophrenia. Furthermore, the data supports that the better premorbid executive function was, the more favorable was the treatment response in schizophrenic patients. Finally, this study indicates that executive function might be an index of treatment improvement.
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