도화탕(桃花湯)이 백서(白鼠)의 소화성(消化性) 궤양(潰瘍) 및 장관수송능(腸管輸送能)에 미치는 영향(影響)

김수정,김진규,백정한,강석봉,이익행,Kim, Soo-Jung,Kim, Jin-Kyu,Back, Jung-Han,Kang, Seok-Bong,Lee, Ik-Haeing 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.2

Objectives : In order to study the clinical efficiency of Dohwatang, based on Oriental Medical References, using experimental animals, we studied ulcers, gastric juice secretion, free acidity, total acidity, and the action of transport rates in the intestine. Methods : We used rats administered with the above herbs. Results : Dohwa-tang showed remarkable inhibitory effects on peptic ulcers, gastric juice secretion, free acidity, and total acidity in pyloricligated rat. It also showed remarkable inhibitory effects on the transportability in the large intestine of rats. But Dohwa-tang didn't show any remarkable difference on stressed rats. Conclusions : Dohwatang works better for chronic pyloristenosis-peptic ulcer and for diarrhea than acute stress ulcer.

$(1-x)CaWO_4-xYNbO_4$계 세라믹스의 마이크로파 유전특성

김수정,김응수,Kim, Su-Jung,Kim, Eung-Soo 한국결정성장학회 2007 한국결정성장학회지 Vol.17 No.5

[ $(1-x)CaWO_4-xYNbO_4$ ]계에 대하여 $YNbO_4(0.05{\leq}x{\leq}0.4)$의 치환량 변화에 따른 마이크로파 유전특성을 고찰하였다. x=0.10 조성까지 정방정(tetragonal) scheelite 구조의 $CaWO_4$ 단일상이 확인되었고, 그 이상 첨가 시 fergusonite 구조의 2차상이 증가하였다. $YNbO_4$ 첨가량이 증가할수록 겉보기 밀도는 감소하였는데, 이는 $CaWO_4(6.117g/cm^3)$보다 $YNbO_4(5.581g/cm^3)$가 더 낮은 이론밀도 값을 갖기 때문이다. $YNbO_4$의 첨가량이 증가함에 따라 유전상수(K)와 품질계수(Qf)는 2차상의 증가와 밀도의 감소로 인해 감소하는 경향을 보였고, $YNbO_4$ 치환량에 따른 소결시편의 공진주파수 온도계수(TCF)의 변화는 존재상의 유전체 혼합 법칙(dielectric mixing rule)에 의존하였다. Microwave dielectric properties of $(1-x)CaWO_4-xYNbO_4$ ceramics have been investigated as a function of $YNbO_4$ content($0.05{\leq}x{\leq}0.4$). A single phase with tetragonal scheelite structure was obtained up to x=0.10 and then the secondary phase with fergusonite structure was increased. With the increase of $YNbO_4$ content, apparent densities of the specimens were decreased. This results were due to the lower theoretical density of $YNbO_4(5.581g/cm^3)$ than that of $CaWO_4(6.117g/cm^3)$. Dielectric constant(K) and quality factor(Qf) were decreased with $YNbO_4$ content which could be attribute to the decrease of density and the increase of secondary phase. Temperature coefficient of resonant frequency (TCF) of the specimens with the $YNbO_4$ content was depended on dielectric mixing rule.

건성피부 및 소양증에 대한 잘스밍R 크림의 임상효과에 대한 연구

김수정,이인욱,최응호,이원수,안성구 ( Soo Jung Kim,In Wook Lee,Eung Ho Choi,Won Soo Lee,Sung Ku Ahn ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.3

Background: Xerosis is a relatively common disorder, especially in the elderly. The condition is characterized by fine scaling and is associated with generalized pruritus. Objective : The purpose of this study was to evaluate the clinical efficacy, safety and tolerability of Zalsming cream in patients with xerosis and pruritus. Methods : Thirty patients were treated with Zalsming cream. Clinical efficacy, as measured by the score of subjective symptom and objective signs, transepidermal water loss(TEWL) and electron microscopic finding, were asessed at 2, 4, and 6 weeks after topical application of the cream. Results . The scores of clinical signs and TEWL showed statistically significant improvements. No one developed any local or systemic side effects. Conclusion : Topical application of Zalsming cream was found to be effective and safe for patients suffering from xerosis and pruritus. (Kor J Dermatol 1997;35(3): 418-423)

홍경천(Rhodiola sachalinensis A. Bor)의 캘러스 배양에서 Salidroside생산

김수정,황백,황성진,안준철,Kim, Soo-Jung,Hwang, Baik,Hwang, Sung-Jin,Ahn, Jun-Cheul 한국식물생명공학회 2004 식물생명공학회지 Vol.31 No.1

본 실험은 기내 배양된 홍경천으로부터 캘러스를 유도하고 가장 잘 자라는 생장조건을 찾기 위해 수행되었다. 실험 결과를 종합해 보면 캘러스의 증식을 위한 배양조건은 최적배지를 조사한 결과,2B$_{5}$배지에서 생장율이 가장 좋았으며, 탄소원으로는 sucrose를 3%로 첨가했을 때 생장율이 가장 높았다. 질소원으로써는 49.6mM KNO$_3$와 2.0mM (NH$_4$)$_2$SO$_4$를 첨가했을 때 생장율이 가장 좋았으며, 인산의 농도는 2.16mM에서 높은 생장율을 보였다. 암배양과 광배양을 비교했을 때 암배양의 경우가 생장율이 높았으며,pH6에서 세포의 생장율이 가장 좋은 조건임을 확인되었다. 기내에서 배양된 캘러스와 자연산 뿌리는 TLC로 분석하여 salidroside를 확인하였으며, HPLC로 salidroside를 정량한 결과, 자연상태 홍경천의 뿌리는 건중량 당 0.17%으로 나타났으며 5% sucrose처리구에서 0.41%의 생산성을 보여, 자연산 홍경천의 뿌리에 비하여 캘러스에서 salidroside의 함량이 높은 것으로 나타났다. Callus of Rhodiola sachalinensis A. Bor were induced from leaf explant on l/2MS solid supplemented with combination of auxin (2.4-D, NAA: 0.1∼2mg/L) and cytokinin (BA: 0.1∼0.2mg/L). The effects of various medium, culture conditions and phytohormones on the growth of callus were investigated. MS, WPM, B$_{5}$ medium and diluted or concentrated media (1/2X, 2X, 3X) were used to investigate the growth of callus on each media. Among these, the highest growth was observed when cultured in in 2B$_{5}$ medium containing 0.5mg/L NAA and 1mg/L BA, 3% sucrose and 49.6 mM KNO$_3$ as nitrogen source, and 2.16mM NaH$_2$PO$_4$ as phoshate source at $25^{\circ}C$ in the dark. The calli cultured with 5% sucrose produced high salidroside content (0.41% on the basis of dry wt) than normal root (0.17%).

감귤 내 생리활성성분이 간암세포의 생존에 미치는 영향

김수정,박덕배,Kim, Soo Jung,Park, Deok Bae 제주대학교 의과학연구소 2018 The Journal of Medicine and Life Science Vol.15 No.1

Previous studies have suggested that Citrus fruits might suppress the proliferation of various cancer cells. However, little is known about any specific ingredients in the extract of Citrus fruits to exert its anti-proliferative activity in cancer cells. The present study aimed to identify the active ingredients in Citrus fruits to suppress the proliferation of rat hepatocellular carcinoma cells. Among tested compounds, two polymethoxylated flavones (nobiletin and tangeritin) showed significant anti-proliferative activity whereas other compounds (synephrine, rutin, hesperidin) did not. Interestingly, nobiletin as well as tangeritin also decreased the protein amount of gluconeogenic enzymes, PEPCK and G6Pase. The possible involvement of gluconeogenic activity in the proliferation of hepatocellulacarcinoma cells are further to be investigated.

영어의 비강세 약모음 schwa /e/의 음성실현

김수정,Kim, Soo-Jung 한국음성학회 2005 음성과학 Vol.12 No.4

The present study examines the phonetic realizations of the unstressed weak vowel /e/ in English words produced by native and Korean ESL speakers. Traditionally, the stressed elements in utterance are considered to be prominent. In this sense, the unstressed weak vowel /e/ is predicted to be shorter in length, lower in pitch and intensity than the stressed vowels. The experiment shows that native English speakers correlate the unstressed weak vowel /e/ with both shorter duration and lower pitch; Korean ESL speakers correlate it with lower pitch only. We cannot find any significant statistical difference in intensity between /e/ and the stressed vowels in both cases. This study suggests it is important to acquire and produce the correct prosodic correlates of the unstressed weak vowel /e/ for Korean ESL speakers to command more natural English intonation, since /e/ is the most common vowel in English speech and consists of the English foot rhythm along with stressed vowels.

Wegener 육아종증

김수정 ( Soo Jung Kim ),박상훈 ( Sang Hoon Park ),이광훈 ( Kwang Hoon Lee ),방동식 ( Dong Sik Bang ),이수곤 ( Soo Kon Lee ) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.6

Wegener's granulomatosis is a systemic necrotizing vasculitis of unknown cause. The disease is characterized by the involvement of the upper airway, the lung, and the kidney. Skin lesions are frequent and the most common lesion is purpura distributed on the limbs and trunk. A 34-year-old female showed recurrent purpuric macules on the both lower extremities and buttocks. The patient. showed nasal septal perforation with saddle nose deformity and C-ANCA positivity. Histopathologic findings of purpuric lesion revealed the features of necrotizing vasculitis. The histologic specimen from the nasal cavity showed chronic inflammation with granuloma formation and kidney showed focal necrotizing glomerulonephritis. Therefore, we treated the patient with prednisolone and cyclophosphamide having diagnosed Wegener's granulomatosis. (Kor J Dermatol 1995;33(6): 1129-1133)

한국 기업의 해외직접투자 군집효과에 대한 실증분석

김수정(Soo Jung Kim),허정(Jung Hur) 한국경제연구학회 2015 한국경제연구 Vol.33 No.2

본 연구는 1997년부터 2008년까지 우리나라의 해외직접투자에 대한 지역 결정 요인과 산업 내 군집효과를 다루고 있다. 지역 결정요인에 대한 결과로는, 대기업은 시장접근형의 투자가 활발히 이루어지고 있는 반면, 중소기업은 투자국의 임금과 인프라 수준에 민감하게 반응함이 나타났다. 군집효과에 대한 결과로, 첫째 대기업 투자는 연관산업의 대기업 군집도에는 영향을 받지 않지만, 연관산업의 중소기업 군집도와 동일 산업의 대기업 및 중소기업 군집도에는 영향을 받는 것으로 나타났다. 둘째, 중소기업의 경우에는 연관산업과 동일 산업 모두 대기업 및 중소기업 군집도에 영향을 받는 것으로 나타났다. 이는 현지 국내 기업들 간 수직적 연계성과 군집으로부터 발생하는 신호, 외부효과의 이점, 동일 기업군 간 경쟁이 반영된 결과라 할 수 있다. This study deals with industrial agglomeration of foreign direct investment of Korean firms from 1997 to 2008. We find that large firms` foreign direct investments in an industry were affected by small-and-medium firms` agglomeration within related industries and large firms` agglomeration in the same industry, but not affected by large firms` agglomeration within related industries. But, small-and-medium firms` foreign direct investment in an industry are affected by all kinds of firms` agglomeration in all industries. The results reflect domestic firms` vertical relatedness and signaling from industrial agglomeration in foreign markets, positive externality, and competitions among firms in same groups.

주거공간 디자인 교육사례 연구

김수정(Kim, Soo-Jung) 한국실내디자인학회 2016 한국실내디자인학회 학술대회논문집 Vol.2016 No.6

회상하기 프로그램이 알츠하이머 노인의 의사소통 능력에 미치는 영향

김수정(Kim, Soo-Jung),장현진(Chang, Hyun-Jin) 대한신경계작업치료학회 2020 재활치료과학 Vol.9 No.4

목적: 회상하기는 알츠하이머 치매 환자에게 심리적 측면에서 안정을 찾는 방안이면서 동시에 자신의과거를 기억하면서 자신에 대해서 정확하게 표현하면서 의사소통에 대해 접근하는 방법이다. 따라서, 이 연구는 알츠하이머 치매노인에게 회상하기 프로그램에 적응하여 의사소통 능력의 효과를 알아보고자 한다. 연구방법: 본 연구는 70세 노인 중 알츠하이머 치매(Alzheimer’s dementia; AD) 노인 4명을 대상으로 사전-치료-사후 평가 단계를 구성하여 실시하였다. 결과: 첫째, 의사소통 요소 중 회화항목 영역에서 중재 후에 향상되었다. 둘째, 의사소통 요소 중 인지력 인식 영역에서 중재 후에 향상되었다. 셋째, 의사소통 요소 중 커뮤니케이션 영역에서 중재 후에 향상되었다. 결론: 이 연구에서는 회상하기 프로그램이 알츠하이머 치매 노인이 의사소통능력의 향상에 긍정적 영향을 미쳤다. 회상하기 프로그램을 바탕으로 추후 치매 노인의 의사소통 능력을 향상시키는데 많은 도움이 될 것으로 사료된다. Objective : Reminiscence program is a method to restore psychological stability for the elderly having dementia, and at the same time it makes the aged with dementia express themselves correctly by helping them to recollect their past life memories. The purpose of this study was to investigate the effects on communication ability in applying the reminiscence program to elderly patients with Alzheimer’s dementia. Methods : The subject were 4 patients whose Alzheimer’s dementia of moderate. This experiment was designed with pre-stage, treatment-stage, post-stage. The reminiscence therapy was compose of reminiscence activities of their live; in their childhood, adolescence, adulthood, and senescence. The therapy was delivered 30 times for 15 weeks. Results : The result of the study were as follows. First, after reminiscence therapy, recognition ability was improved. Second, after reminiscence therapy, emotional side was improved. Third, after reminiscence therapy, communication ability was improved. Conclusion : In this study, the reminiscence therapy had a positive effect on the improvement of communication skills among the elderly with Alzheimer’s dementia. Based on the reminiscence therapy, it is thought to be very helpful in improving the communication ability of the elderly with dementia in the future.