차량 운전자의 공기오염물질 잠재적 노출 및 차량용 공기청정기에 의한 제어

김대원,김문현,양원호,Kim Dae-Won,Kim Moon-Hyeon,Yang Won-Ho 한국환경보건학회 2004 한국환경보건학회지 Vol.30 No.5

Vehicle occupant exposure to air pollutants has been a subject of concern in recent years because of higher levels of air pollutants inside gasoline or diesel-using vehicle, comparing to the surrounding atmosphere. Contrary to previous studies, fuel of vehicles operated in this study was liquefied petroleum gas (LPG). This study examined the potential exposure and removal efficiency of selected volatile organic compounds (VOCs), nitrogen dioxide ($NO_2$) and respirable suspended particle (RSP) by commercial air cleaning device inside vehicle under different ventilation conditions. Vehicle concentrations inside of benzene, toluene, m,p-xylene, $NO_2$ and RSP were lower under the low ventilation condition. This was indicated that outdoor air pollutants could affect the vehicle air quality inside in case metropolitan cities such as Daegu. The urban vehicle concentrations inside of benzene, toluene, m,p-xylene, $NO_2$ and RSP with air cleaning device were higher than those without air cleaning device. This means that the use of air cleaning device equipped with activated carbon filter, which was used in this study, in the interior of vehicles could be expected to reduce the vehicle occupants exposure to air pollutants effectively. In batch type reactor of laboratory scale, removal efficiencies of air cleaning device used were $97.0\%,\;95.7\%,\;94.6\%\;and\;85.5\%$ respectively in benzene, toluene, m,p-xylene and $NO_2$.

사람 교모세포종 A172 세포에서 Cisplatin에 의한 세포고사의 유도

김대원,김태영,박종태,김종문,Kim, Dae Won,Kim, Tae Young,Park, Jong Tae,Kim, Jong Moon 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.1

This study was designed to investigate the mechanism of cell death after cisplatin treatment in human glioblastoma A172 cells. Cis-diamminedichloroplatinum(Cisplatin) demonstrated cytostatic or cytotoxic effects on A172 cells in a dosedependent manner. Cisplatin-mediated cytotoxity in A172 cells was revealed as an apoptosis characterized by high molecular weight DNA fragmentation by agarose electrophoresis as well as nuclear fragmentation by Hoechst staining. Cisplatin also resulted in the activation of caspase 3-like protease as well as poly(ADP-ribose) polymerase(PARP) cleavage. Interestingly, the anti-apoptotic Bcl2 protein was degraded and furthermore, expression of p53 protein was increased by cisplatin in a time-dependent manner. Taken together, these results suggest that anticancer drug, cisplatin induces the apoptotic death of human glioblastoma A172 cells via the activations of caspase 3-like protease, degradation of anti-apoptotic Bcl2 protein and increase in the expression of p53.

JPEG2000 정지영상을 위한 블록 에너지 기반 적응적 이산 웨이블릿 변환

김대원,Kim, Dae-Won 한국융합신호처리학회 2007 융합신호처리학회 논문지 (JISPS) Vol.8 No.1

본 논문에서는 웨이블릿 변환에 기반을 둔 JPEG2000 정지영상의 압축 시도 시 웨이블릿 변환을 decomposition 하는 레벨과 이를 구성하는 블록의 활성도를 내포하는 에너지에 기반 하여 그 양에 따라 적응적으로 계수 변환 후 복원시 효율적 자원 관리를 통하여 복잡도를 감소시키고 계산량을 줄이는 적응식 DWT 변환 기법을 제안하였다. 수많은 멀티미디어 응용 분야 또는 서비스 중의 하나인 디지털 카메라의 핵심 분야를 차지하고 있는 정지영상 압축 분야에서의 최첨단 기술을 꼽으라면 단연 JPEG2000 표준을 이용한 압축, 전송의 응용 분야이다. JPEG2000 기반의 정지영상압축 전송 표준의 핵심을 이루고 있는 웨이블릿 변환은 기존의 JPEG 표준에 사용된 이산 코사인 변환의 약점인, 복원 시 나타나는 블록킹 문제를 해결한 대안이다. 적응식 DWT 변환을 거친 정지영상이 복원된 후 일반적인 과정의 웨이블릿 변환 후 복원된 영상간의 MSE(Mean Square Error), PSNR(Peak Signal to Noise Ratio), 0의 계수의 개수 등을 비교하여 본 연구에서 제안된 에너지 기반의 적응적 웨이블릿 변환의 우수성을 연산 속도를 계산함으로써 검증하였다. The proposed algorithm in this paper is based on the wavelet decomposition and the energy computation of composed blocks so the amount of calculation and complexity is minimized by adaptively replacing the DWT coefficients and managing the resources effectively. We are now living in the world of a lot. of multimedia applications for many digital electric appliances and mobile devices. Among so many multimedia applications, the digital image compression is very important technology for digital cameras to store and transmit digital images to other sites and JPEG2000 is one of the cutting edge technology to compress still images efficiently. The digital cm technology is mainly using the digital image compression features so that those images could be efficiently saved locally and transferred to other sites without any losses. JPEG2000 standard is applicable for processing the digital images usefully to keep, send and receive through wired and/or wireless networks. The discrete wavelet transform (DWT) is one of the main differences to the previous digital image compression standard such as JPEG, performing the DWT to the entire image rather than splitting into many blocks. Several digital images m tested with this method and restored to compare to the results of conventional DWT which shows that the proposed algorithm get the better result without any significant degradation in terms of MSE & PSNR and the number of zero coefficients when the energy based adaptive DWT is applied.

25 Vitamin D3 측정에 있어서 화학발광미세입자 측정법과 화학발광면역 측정법 간의 비교 및 고찰

김대원,이정희,정안나,서소연,Kim, dae-won,Lee, jung-hee,Jung, an-na,Seo, so-yoen 대한핵의학기술학회 2015 핵의학 기술 Vol.19 No.2

Purpose Vitamin D to Anti- Rickets both steroid compounds showing activity, By acting on bone tissue secretary and the key to maintain serum Ca homeostasis. The blood level of vitamin D is the largest in D3 that the concentration of the metabolite is reflected in the holding state of vitamin D in vivo. Sunlight to change the 7-dehydrocholesterol in the skin and through the skin to D3, In the liver in combination with the D2 and D3 D4 changes. The Radioimmunoassay(RIA) method is measuring the D 3, the sensitivity can be measured also difficult trace substance to measure the normal test because it is very sensitive, but recently, a check is possible, for the Total D3 in Chemimicroparticle immunoassay(CMIA) or Chemiluminescent immunoassay(CLIA) measuring using microparticle RIA and CMIA(Architect i2000SR) / use the CLIA(DXI-800) method to compare and evaluate the correlation between the tests in the same test items. Materials and Methods Commissioned from January 2014 to March 2015 patients were enrolled in a total of 273 people. 29 out of 273 people conducted by RIA were compared with CMIA, 244 patients were compared with CLIA. Using reagents and equipment were used RIA(Diasource), CMIA(Architect i2000SR, Abbott Diagnostics) / CLIA( Unicel DXi-800, Beckman coulter). Results Correlation of the RIA and CLIA was a R2 = 0.1844 (y = 0.7303x + 3.9005), and the correlation of RIA CMIA is R2 = 0.2762 (y = 0.8862x + 4.56) respectively. (According to statistics, during the same period RIA is Deficiency 4.31%, Insufficiency 90.53%, Sufficiency 5.16%, was Excess 0%, CLIA / CMIA is Deficiency 17.02%, Insufficiency 75.91%, Sufficiency 7.03%, indicating the distribution of 0.03 % Excess) Conclusion Serum vitamin D and parathyroid hormone that show an inverse relationship, the level above which are not parathyroid hormone and vitamin D reduced the increase. The density is different for each study, at most 20 is reported to be the maximum between 30 ng / ml. In Korea it requires a proposed standard of vitamin D deficiency, reference to the WHO lack the case more than 10ng/ml, 20ng/ml and defined by the lack of, if not more than, the IOM, but looking at 12ng/ml or less to the normal to lack, at least 20ng/ml, the reference do not match the deficit under 20ng/ml, 21-29ng/ml relative lack between, was also defined as a sufficient condition for more than 30ng/ml. Although not statistically is between RIA and CLIA two ways to vitamin D levels change according to season match, when seasonally seen in summer as commonly known (April to September), winter (October to March) relative to the increase measured than it was found. Finally, the study on the correlation between the two methods have been expected to result in a consistent and apply the same view high reference value on the graph is difficult. However, there may be differences between the test equipment and methods, and could be especially the case of RIA method using an organic solvent is difficult to compare different methods and correlated view similar trend in vitamin D deficiency and quarterly aspect ratio.

The Clinical Outcomes after Embryo Transfer (ET) on Day 2 and Day 5 or Subsequent ET on Day 2-5, 2-6, 2-7, 3-5 and 4-7 in In Vitro Fertilization-ET Cycles

김대원,박기상,송해범,이택후,전상식,Kim, Dae-Won,Park, Kee-Sang,Song, Hai-Bum,Lee, Taek-Hoo,Chun, Sang-Sik The Korean Society for Reproductive Medicine 2003 Clinical and Experimental Reproductive Medicine Vol.30 No.1

연구목적: 일반적으로 IVF-ET에서 가장 높은 임신율을 얻는 방법은 5 day ET (배반포기 배아 이식)이지만 장기간 배양이 적절하지 못한 경우에는 $2{\sim}4$일째에 ET를 실시하고 나서 $5{\sim}7$일째에 배반포기에 도달한 배아를 재이식 (SET)하여, SET의 효용성에 대하여 조사하고자 실시하였다. 연구재료 및 방법: 48주기의 환자에서 회수한 난자와 수정란은 10%와 20% hFF가 첨가한 DMEM에서 이식 직전까지 각각 공배양하였다. 채란 2일 (group I, day 2 ET), 5일째 이식 (group II, day 5 ET) 또는 재이식 (group III, SET; 2-5, 2-6, 2-7, 3-5, 4-7일)을 실시하면서 수정률, 할구분할률 및 임신율을 각각 비교하였다. 결과에 대한 통계 분석을 SAS (version 6.2)를 이용한 Duncan's Multiple Range Test를 이용하여 p값이 0.05 보다 작을 때 통계적으로 유의차가 있는 것으로 하였다. 결 과: 수정률은 group II (90.5%)가 다른 군에 비하여 높게 (p<0.05) 나타났다 (group I: 80.6%; group III: 82.9%). 할구분할률은 군간에 차이가 없었다 (수정란 당 $93.3{\sim}99.1%$). 임상적 임신율은 group II와 III (각각 58.3%)가 group I (33.3%) 보다 높게 나타났다. 그러나 처리군이 적어서 통계적인 차이는 없었다. 결 론: 배반포기 배아를 단독 이식하는 것이 임신율을 높일 수 있는 최선의 방법으로 나타났지만, 채란수가 적거나 수정률이 저조한 경우에는 $2{\sim}4$일째에 ET를 실시한 후 여분의 배아를 배반포기까지 배양한 다음 $5{\sim}7$일에 재이식 (SET)하면 blastocyst ET에서 나타날 수 있는 이식 자체의 실패를 방지할 수 있으면서 임신율을 높일 수 있는 이식 기법이 될 것이다.

Glass fiber 제조설비의 기술 동향

김대원,김종수,강희신,Kim, Dae-Won,Kim, Jong-Su,Gang, Hui-Sin 재료연구소 2007 機械와 材料 Vol.19 No.3

제 1 형 신경섬유종증과 동반된 교육종

김대원,박종태,김종문,김태영,Kim, Dae Won,Park, Jong Tae,Kim, Jong Moon,Kim, Tae Young 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.2

A rare case of gliosarcoma with neurofibromatosis type I is presented. The patient was a 33-year-old woman who had headache and vomiting for one week. Multiple neurofibromas over her whole body with many cafeau- lait spots were present since childhood. At admission, she had no focal neurological deficit and ophthalmologic examination revealed bilateral Lisch nodules. Brain CT and MRI revealed a heterogeneously enhancing mass in the left fronto-parietal region with marked peritumoral edema and mass effect. The tumor was removed gross totally and a gliosarcoma was diagnosed histopathologically. Post operative course was uneventful with resolution of symptom, followed by radiotherapy with 60 Gy. A brief overview is given of this rare case together with the pertinent literature.

공동주택 연도별 단열기준 강화에 따른 에너지소요량 비교 연구

김대원,정광섭,김영일,김성민,Kim, Dae-Won,Chung, Kwang-Seop,Kim, Young-Il,Kim, Sung-Min 한국에너지학회 2013 에너지공학 Vol.22 No.2

에너지사용은 우리생활과 밀접한 관계성을 유지하고 있다. 사계절이 뚜렷한 우리나라로서는 건물분야에 냉,난방이 필수품처럼 여겨지는 세대에 살고있어 에너지 사용과 유지에 새로운 트렌드를 요구하고 있다. 이에따라 정부는 신축 및 기존건축물의 에너지효율 개선을 위해서 단열기준을 지속적으로 강화하여 에너지절감을 꾀하고 있다. 공동주택의 에너지효율 분석중 가장 중요한 요소가 열관류율이며 그값은 외피면적비에 대한 창면적비에 따라 난방에너지 요구량이 큰차이를 보여주고 있다. 그러므로 지속적인 효율개선 정책과 외피면적에 대한 창면적비의 규제가 필요한 시점이라 생각한다. Energy consumption is closely related to our lives. As Korea has four seasons, heating and cooling system is considered as essential facilities for the residential buildings. Accordingly, the government has continuously strengthened the design criteria to improve energy for new and existing building to save energy. The most important factor in the energy efficiency analysis for apartment is the heat transmission coefficient, and the value is significantly different as the heating energy amount is greatly different according to the window area ratio versus facade area ratio. Therefore, it is time to conduct continuous set-up for goal to enhance efficiency and restriction on window area ratio versus facade area ratio.

Traffic Analysis of a CAN-based Control System

김대원,Kim, Dae-Won Institute of Korean Electrical and Electronics Eng 2001 전기전자학회논문지 Vol.5 No.1

This paper deals with an architecture of network-based control system using the CAN(Controller Area Network) protocol and its traffic analysis. It is difficult to determine an optimal network-based control architecture for a specific AGV(Autonomous Guided Vehicle) system with a manipulator arm. The fixed number of periodic messages to be occurred is pre-defined in the system. To determine whether the proposed system architecture is effective or not, we perform traffic analysis for the real-time communication of all messages. Through simulations, the range of transmission speed is found satisfying required conditions and the permissible number of additional sensors is investigated for improving the system performance, when the sampling periods of analog sensors are determined under fixed condition that the transmission speed is over 500Kbps.

산업용 로봇 기술의 현황 및 전망

김대원,이범희,Kim, Dae-Won,Lee, Beom-Hui 재료연구소 1993 機械와 材料 Vol.5 No.3