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자울약침액(紫菀藥鍼液)의 폐유(肺兪) 처치(處置)가 Type I Hypersensitivity에 미치는 영향
권혁상,송춘호,Kwon, Hyuk-Sang,Song, Choon-Ho 대한침구의학회 2006 대한침구의학회지 Vol.23 No.5
Objectives : We studied the effects of Radix Asteris herbal acupuncture solution (RAHAS) on the type I hypersensitivity. Methods : In vivo, we measured compound 48/80 induced active systemic anaphylactic shock, anti-DNP IgE induced passive cutaneous anaphylaxis (PCA) and acetic acid induced microvascular permeability using ICR mice. In vitro, we showed effects on cytotoxicity and ${\beta}$-hexosaminidase release from RBL-2H3 cells. Results : In vivo, RAHAS pretreatments at $BL_{13}$ and optional points inhibited active systemic anaphylactic shock induced by compound 48/80 and microvascular permeability increased by acetic acid. PCA was only inhibited by RAHAS pretreatments at $BL_{13}$. In vitro, RAHAS treatments inhibited ${\beta}$-hexosaminidase release. Conclusion : These results suggest that RAHAS may be beneficial in the prevention of type I hypersensitive inflammatory response.
반지련 약침 추출물의 RBL-2H3 세포 탈과립과 염증매개물질 분비 억제 효과
권혁상 ( Hyuk Sang Kwon ),송춘호 ( Choon Ho Song ) 경락경혈학회 2012 Korean Journal of Acupuncture Vol.29 No.3
Objectives : Scutellaria barbata has been widely used in oriental medicine used for treatment of acute and chronic inflammatory diseases. In this study, to investigate the protective effect of Scutellaria barbata on type I allergic response, we determined whether Scutellaria barbata inhibits early or late allergic responses. Methods : To assess the effect of Scutellaria barbata Pharmacopuncture Extract(SB) in RBL-2H3 cells, we investigated the levels of the markers of degranulation such as β-hexosaminidase and histamine, inflammatory mediator such as IL-4, TNF-α, PGE2 and cysLT, and mRNA expression of cytokines and enzymes. In addition, we determined the levels of intracellular ROS by DCFH-DA assay and the free radical scavenging activity by DPPH method. Results : We found that SB suppressed the release of β-hexosaminidase and histamine and the production of IL-4, TNF-α, PGE2 and cysLT in RBL-2H3 by the antigen stimulation. SB also significantly inhibited the enzyme mRNA expressions, such as HDC2, COX-1, COX-2, 5-LOX and iNOS2, along with reduced cytokine mRNA expressions, such as IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-13, TNF-α and GM-CSF in RBL-2H3. In addition, SB suppressed the levels of intracellular ROS. Conclusions : Our results indicate that SB protects against type I allergic response and exert an anti-inflammatory effect through the inhibition of degranulation, inflammatory mediator release and mRNA expression of cytokines and enzymes.
군중 속의 그리스도: 추상화를 통해 본 예술의 기독교적 의미와 가능성
권혁상(Hyuk Sang Kwon) 한신대학교 신학사상연구소 2018 신학사상 Vol.0 No.183
이 논문은 기독교 신앙과 예술의 관계에 대해 고찰한다. 통상 특정한 주제들을 다루는 예술 작품들만이 기독교적 의미를 갖는 것으로 여겨지는 경우가 많다. 그러나 본고는 일군의 현대 신학자들의 주장을 토대로 예술 자체에 내재한 신앙적 함의와 가능성을 조명한다. 즉, 물질을 매개로 감각에 작용하는 예술 작품들은 그 자체로 감상자에게 성육신과 창조의 의미를 상기시키고 고취시킬 수 있는 가능성이 있음을 주장한다. 나아가 본고는, 기독교에서 이해하는 성령의 역할에 입각하여, 추상적인 방식으로 그려진 시각 미술들이 가질 수 있는 신앙적 가능성에 대해서도 고찰한다. 마지막으로, 서예적 추상이라는 기법으로 그려진 서세옥의 그림들을 사례 삼아 추상적 예술이 성육신을 중심으로 하는 기독교적 세계관을 강화하고 고취하는 양상을 구체적으로 살펴본다. 전반적으로 본고는 진리를 비담화적인 방식으로 담아낼 수 있는 예술이 담화를 넘어 결국 존재와 양상으로 자신의 신앙을 드러내야 할 기독교 신자들에게 필요하다는 것을 주장한다. This article examines the Christian significance of the arts. Questioning some conventional approaches to the concept of Christian art, the article sheds light on some Christian implications that can be found in artistic works, no matter what the theme or message they may have; it argues that artistic works intrinsically have a potential to draw the viewers to the realization and appreciation of the Christian truth of incarnation and creation, especially owing to the physical and sensory dimension they have. Based on the Christian understanding of the Holy Spirit, this article also explores how artistic works which have abstract form and color can be relevant to Christian faith. Finally, it ponders over some abstract paintings of Korean calligraphy, in order to show how such works can arouse the Christian understanding of the human, and thereby inspire the Christian world-view in us. It concludes that art is worthy of more attention from Christians whose goal is to embody their faith and knowledge by their image and existence.
제2형 남자 당뇨병환자에서 비만과 비비만에 따른 아디포넥틴의 혈중 농도와 다중결합체의 차이
장상아 ( Sang Ah Chang ),손호영 ( Ho Young Son ),이정민 ( Jung Min Lee ),손태서 ( Tae Seo Sohn ),권혁상 ( Hyuk Sang Kwon ),손현식 ( Hyun Shik Son ),윤건호 ( Kun Ho Yoon ),김희승 ( Hee Seung Kim ),차봉연 ( Bong Yun Cha ),이광우 ( K 대한당뇨병학회 2007 Diabetes and Metabolism Journal Vol.31 No.3
계층화 분석법(Analytic Hierarchy Process)을 활용한 한의사 업무량 산출
임병묵,권혁상,한창호,신병철,Lim, Byung-Mook,Kwon, Hyuk-Sang,Han, Chang-Ho,Shin, Byung-Cheul 대한예방한의학회 2009 대한예방한의학회지 Vol.13 No.1
Background: The resource-based relative value scale has been applied to Korean medicine services as part of the National Health Insurance, yet the proper scoring method for physician's work needs to be developed. Objectives: To measure physician's work for Korean medicine services using Analytical Hierarchy Process(AHP) and to compare results abstracted by AHP with those by Magnitude Estimation method. Methods: We developed the AHP questionnaires for Korean Medicine services and administered it to 12 Korean medicine insurance experts. Weighted scores were calculated and were converted into physician's work scores. Results: In AHP measurement, the physician's work scores for acupuncture activities, especially special acupunctures, far increased, while those for diagnosis and basic consultations decreased. Variations in the scores enlarged. Conclusions: As an alternative, AHP method can be considered for measuring the physician's work for Korean medicine services with careful management of scoring variation.