뇌사판정에서 두개경유도플러초음파의 유용성

권병주,권지현,김욱주 대한신경과학회 2015 대한신경과학회지 Vol.33 No.2

민중운동(民衆運動)과 민중혁명론(民衆革命論)에 대한 비판적(批判的) 고찰(考察)

권병주 국방대학교 안보문제연구소 1988 국방연구 Vol.31 No.1

라틴아메리칸 댄스 경기종목별 운동강도 추정

권병주(Byoung Ju Kwon),오윤선(Youn Sun Oh) 한국사회체육학회 2007 한국사회체육학회지 Vol.0 No.30

The purpose of this study was to predict the intensity of each item in Latin American dances and display the scientific exercise prescription to the dancers for the dance competition. Dance sports players(n=12) were tested with physical fitness test and cardiopulmonary exercise test(Bruce protocol). The heart rate, VO2 max, and energy consumption were measured during the simulated competition(Rumba, Cha Cha Cha, Jave, Samba, Paso Doble). The physical fitness test results showed significant differences. The sit and reach test in woman players was significantly higher than that in man player. Back strength in man players(127.25±16.13) were higher than that in woman players(75.83±11.26). cardiopulmonary exercise test(Bruce protocol) displayed that VO2 max, VE max, HR max, exercise time, and VO2 at VT in man players were significantly higher than those in woman players. In order to get the data of heart rate and relative intensity of exercise during the simulated competition, the heart rate was measured in each competition item. Players got the enough rest time in each item during measuring the heart rate. The heart rate and relative intensity of exercise did not show any significant difference. However, the relative intensities of Cha Cha Cha and Rumba in woman players was higher than those in man players. The relative intensities of Samba and Paso Doble in woman players were higher than those in man players. The relative intensity of Jave showed significant difference between man and woman players. Dance players performed one dance item for 1minutes 30 seconds, got the 10 seconds of rest time and performed next dance item. The recovering heart rate of Rumba at 50 seconds in man players(111.17±11.41) was significantly higher than that in woman players. The heart rate in each item and recovering heart rate did not show any significant differences between man and woman players. No significant difference was found for man and woman players in lactin acid cardiopulmonary exercise test(Bruce protocol). Dance sports is a non-aerobic exercise performed during one minute 30 seconds. However, five items were performed for 9minutes during the simulated competition. Dance sports may be an aerobic exercise as the results of the energy consumption and the heart rate during the simulated competition. Therefore, dance trainers may give the guidance of physical fitness improvement programs throughout the analysis of physical fitness, not only support the adaptation of the dance routine.

A Micro-Costing Analysis of Flexible Bronchoscopic Intubation in a Korean Tertiary Hospital

제의모,권병주,정희교,장철호,이한길,구성욱 한국보건의료기술평가학회 2022 보건의료기술평가 Vol.10 No.1

Objectives: To evaluate the per-procedure cost of flexible bronchoscopic intubation in relation to the monetary value of the practice expense relative value units (RVUs) of the procedure. Methods: A micro-costing analysis of flexible bronchoscopic intubation was performed in the anesthesiology and pain medicine department of a Korean tertiary hospital over the fiscal year 2019. Cost records were collected and then categorized into three cost components: depreciation of reusable flexible bronchoscopes and video equipment, reprocessing, and repairs. The per-procedure cost was calculated by dividing the total annual cost by the annual number of flexible bronchoscopic intubations performed. The resulting per-procedure cost was then compared to the monetary value of the practice expense RVUs of the procedure. Considering that the annual procedural volume would significantly impact per-procedure costs and overall profitability, a deterministic sensitivity analysis (DSA) was conducted. Results: In total, 748 flexible bronchoscopic intubations were performed during the fiscal year. Total annual costs for depreciation of the bronchoscopes and video equipment, reprocessing, and repair were US$ 31,921, US$ 22,268, and US$ 22,948 respectively. The calculated per-procedure cost of the flexible bronchoscopic intubation in the period was US$ 103.1 while the fee listed in the fee schedule and the monetary value of the practice expense RVUs of the procedure were US$ 69.9 and US$ 52.2 respectively. Therefore, the procedure was performed at a loss over the period: the amount that the subject department lost with respect to the practice expense RVUs totaled as much as US$ 38,039. The DSA demonstrated that the procedure would remain unprofitable even if twice the volume of procedures were performed over the same duration (n=1,500). Conclusion: The findings suggest that HIRA’s determination of the practice expense RVUs of the procedure may have been underestimated and thus in need of review and recalculation to achieve adequate compensation. The per-procedure cost would vary by procedural volume and site of practice which indicates that a further multicenter study is required to confirm the study’s findings.

소프트웨어 활용 체외진단 의료기기의 관리 및 규제 개선: 국내외 규제 비교를 통한 국내 규제 개선 방안

임수연,권병주 대한의용생체공학회 2024 의공학회지 Vol.45 No.4

This study compares and analyzes domestic and international regulations on the application of software in In Vitro Diagnostic (IVD) medical devices, proposing improvements for South Korea. The research examines regulatory sta- tuses in Europe, the United States, and Australia, identifying differences in regulatory approaches and definitions. Despite varying methods, all countries recognize the importance of software, though the regulatory scope differs. Considering the current domestic regulations, systematic improvements are essential for sustainable growth. This study suggests regula- tory enhancements and draft guidelines, emphasizing the need for ongoing monitoring and stakeholder input to develop practical solutions.

Enhanced Cellular Responses of Vascular Endothelial Cells on Poly-γ-Glutamic Acid/PU Composite Film Treated with Microwave-Induced Plasma at Atmospheric Pressure

박봉주,권병주,강재경,이미희,한인호,김정구,박종철 한국고분자학회 2011 Macromolecular Research Vol.19 No.6

Poly-γ-glutamic acid (γ-PGA), which is produced by microbial fermentation, is a biodegradable, hydrophilic and non-toxic biomaterial. γ-PGA has many carboxyl groups that makes it a polyanionic biopolymer with swelling ability, biocompatibility and anticoagulant activity. On the other hand, few studies have examined the effect of γ-PGA on the cellular activity of human umbilical vein endothelial cells (HUVECs). The present study evaluated the effects of γ-PGA and fabricated γ-PGA/PU composite films on the attachment and proliferation of HUVECs after treatment with microwave plasma at atmospheric pressure. The results confirmed that γ-PGA is capable of increasing the proliferation and differentiation of HUVECs to form capillary tubes with enhanced alignment and organization. Moreover, the microwave plasma modified γ-PGA/PU composite film was more hydrophilic and the surface roughness was enhanced. In addition, the attachment and proliferation of the HUVECs were increased by the plasma treatment. These results suggest that γ-PGA and surface modified γ-PGA/PU composite can be applied as bioactive and biocompatible materials in vascular tissue engineering but further testing of γ-PGA and γ-PGA/PU composite films will be needed to confirm the potential effects for use in vascular applications.

의료기기 통합정보를 활용한 건강보험심사평가원과 식품의약품안전처의 정보 연계 방안

임수연,정현주,권병주 건강보험심사평가원 2024 HIRA RESEARCH Vol.4 No.1

Nitrogen Grafting onto Polycarprolactone by a Simple Surface Modification with Atmospheric Pressure Glow Discharge (Ar-APGD) and Promoted Neonatal Human Fibroblast Growth

한인호,박종철,권병주,Barbora Vagaska,김봉진,강재경,이미희,김학희,Kang-Kyun Wang,김용록,안준성,이지민,현채영,정재환,임수진 한국고분자학회 2011 Macromolecular Research Vol.19 No.11

Plasma surface modifications of polymer scaffolds using biomolecules such as oxygen, nitrogen, and other active grafting molecules have been studied to enhance biological responses such as cell attachment, spreading,and proliferation. According to the reports, nitrogen grafting requires corrosive or mixture gas environment, or post treatment. This study aimed to evaluate a simple atmospheric pressure plasma surface modification in order to graft nitrogen derivatives and to promote biological responses. In this study, a polycarprolactone (PCL) film was modified within 10 min by argon atmospheric pressure discharge (Ar-APGD). Excited argon atoms, nitrogen atoms,oxygen atoms, and hydroxyl functional groups were observed from the optical emission spectra of the discharge. Decreased carbonyl functional groups and ether functional groups were observed; notably, immobilized nitrogen was observed on the PCL surface after the Ar-APGD treatment. Promoted neonatal Human Dermal Fibroblast (nHDF) growth patterns were observed on the Ar-APGD-treated surface.

Effects of direct current electric-field using ITO plate on breast cancer cell migration

김민성,이미희,권병주,서혁진,구민아,류경은,김도현,박종철 한국생체재료학회 2014 생체재료학회지 Vol.18 No.3

Background: Cell migration is an essential activity of the cells in various biological phenomena. The evidence that electrotaxis plays important roles in many physiological phenomena is accumulating. In electrotaxis, cells move with a directional tendency toward the anode or cathode under direct-current electric fields. Indium tin oxide, commonly referred to as ITO has high luminous transmittance, high infrared reflectance, good electrical conductivity, excellent substrate adherence, hardness and chemical inertness and hence, have been widely and intensively studied for many years. Because of these properties of ITO films, the electrotaxis using ITO plate was evaluated. Results: Under the 0 V/cm condition, MDA-MB-231 migrated randomly in all directions. When 1 V/cm of dc EF was applied, cells moved toward anode. The y forward migration index was -0.046 ± 0.357 under the 0 V/cm and was 0.273 ± 0.231 under direct-current electric field of 1 V/cm. However, the migration speed of breast cancer cell was not affected by direct-current electric field using ITO plate. Conclusions: In this study, we designed a new electrotaxis system using an ITO coated glass and observed the migration of MDA-MB-231 on direct current electric-field of the ITO glass.

선별적 적용을 통한 의료기기 공급내역보고 제도 개선 연구

정현주,임수연,김주완,장원석,권병주 대한의용생체공학회 2023 의공학회지 Vol.44 No.5

The objective of this study is to identify the selective application targets for reporting on details of supply of class 1 and 2 medical devices as part of the improvement of the reports on details of supply of medical device system, and to analyze its effectiveness. Therapeutic materials covered by health insurance and secondhand medical devices were chosen based on the transparency of health insurance coverage and the management of medical device distribution. As a result, approximately 85% of groups can be excluded from the reporting requirements compared to reporting all items under Class 1 and 2 medical devices. This is expected to enhance the efficiency of supply report- ing tasks. Additionally, the information on supply details managed by the regulatory authority can be utilized for sta- tistical analysis and periodic monitoring, serving as fundamental data for the development of medical device-related policies and research in the field of medical devices.