Oral Wound Healing Effects of Acai Berry Water Extracts in Rat Oral Mucosa

강미현,김배환 한국독성학회 2018 Toxicological Research Vol.34 No.2

The objective of this study was to determine the oral wound healing effects of acai berry water extracts (ABWE) in rat oral mucosa. To estimate the anti-oxidative effects of ABWE, the contents of phenolic compounds, and DPPH (1,1-diphenyl-2-picryl hydrazyl) and ABTS (2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)) abilities were evaluated. Wound healing effects of ABWE were tested following 6-day exposure after induction of wound by applying 50% acetic acid to oral mucosa of Sprague-Dawley rats. Macroscopic and histopathological analyses were performed to determine wound healing effects of ABWE. Sodium fusidate (20 mg/g) was used as positive control. ABWE showed significantly high antioxidant effects in all assays, although its potency was weaker than the positive control. From day 3 after treatment, wound healing effects of ABWE were observed in oral mucosa. These wound healing effects were also consistent with histopathological evaluation results. Taken together, these results indicate that ABWE might have potential as an oral wound healing agent in the future.

Short-Term Complications of Percutaneous Endoscopic Gastrostomy according to the Type of Technique

강미현,김재영 대한소아소화기영양학회 2014 Pediatric gastroenterology, hepatology & nutrition Vol.17 No.4

Purpose: The method of percutaneous endoscopic gastrostomy (PEG) tube placement can be divided into the pull and introducer techniques. We compared short-term complications and prognosis between patients who underwent the pull technique and two other types of introducer techniques, the trocar introducer technique and T-fastener gastropexy technique. Methods: Twenty-six patients who underwent PEG were enrolled in this study. We retrospectively investigated the age, sex, body weight, weight-for-age Z-score, underlying diseases, PEG indications, complications, duration of NPO (nil per os), pain control frequency, and duration of antibiotic therapy. The patients were classified into three groups according to the PEG technique. The occurrence of complications was monitored for 10 weeks after the procedure. Results: The age, sex, body weight, and weight-for-age Z-score were not significantly between the three groups. Most patients had cerebral palsy and seizure disorders. Dysphagia was the most common indication for PEG. Major complications occurred in 5 (50%), 4 (66.7%), and 0 (0%) patients in group I, II, and III, respectively (p=0.005). Further, peristomal infection requiring systemic antibiotic therapy occurred in 2 (20%), 3 (50%), and 0 (0%) patients in group I, II, and III, respectively (p=0.04). There was no significant difference between the groups with respect to minor complications, duration of NPO, pain control frequency, and duration of antibiotic therapy. Conclusion: The results indicate that the T-fastener gastropexy technique was associated with the lowest rate of major complications.

일부 치과위생사들의 감정노동, 소진, 직무만족 및 이직의도의 융합 연구

강미현,장선주 한국융합학회 2017 한국융합학회논문지 Vol.8 No.8

본 연구에서 치과위생사를 대상으로 감정노동이 직무만족과 이직의도에 미치는 영향을 분석하고, 감정노동 수준에 따른 직무만족도와 이직의도의 변화정도를 파악하고자 실시하였다. 연구는 대전, 대구 지역에 근무 중인 치과위생사 300명을 대상으로 2016년 4월부터 2016년 11월 까지 조사하였으며, 292명의 자료를 최종 분석 대상으로 하였다. 그 결과 감정노동과 소진은 모든 문항은 양(+)의 연관성으로 나타나, 감정노동이 높을수록 소진은 높게 나타났고(P<.01), 직무만족은 음(-)의 연관성이 나타나 감정노동이 낮을수록 직무만족이 높게 나타났다(P<.01). 또한 이직의도에서 감정노동은 양(+)의 연관성이 나타나 감정노동이 높을수록 이직의도도 높게 나타났다(P<.05). 따라서 치과위생사들의 감정노동을 해소하기 위하여 소진 경험정도와 직무 스트레스를 낮추고 보상과 복지혜택을 늘리는 방안이 모색 되어야한다. Abstract The purpose of this study is to analyze the changes in job satisfaction and turnover intention according to the level of Emotional labor and the mediating effect in dental hygienists. The survey was performed from April, 2016 to November, 2016 against 300 dental sanitarian working in Daejeon and Daegu district and a total of 292 people's data was made an object for final analysis. As a result of it, the emotional labor and exhaustion showed positive relationship and thus as the emotional labor is high, exhaustion was high(P<0.1), and the job satisfaction was negative and thus as the emotional labor is low, the job satisfaction was high(P<0.1) Also, the emotional labor in the turnover intention was positively related and thus as the emotional labor is high, the turnover intention was high(P<0.5). Thus, a scheme to lower the job stress and the exhaustion experience degree and increase the compensation and welfare benefits in order to solve the emotional labor of the dental sanitarian.

비스마르크시대 포젠지역을 중심으로 한 폴란드 정책

강미현 부산경남사학회 1997 역사와 경계 Vol.33 No.-

회원작품 - 삼시세끼하우스

강미현,Kang, Mihyun 대한건축사협회 2017 建築士 Vol.578 No.-

다가구 주택 지하층 거주실태

강미현,김은경,류영신,이정아,이혜정,황희정 연세대학교 생활과학대학 1994 婦學 Vol.27 No.-

건축설계 실무과정에서 디자인 프로세스의 적용에 관한 연구

강미현,김소라,신병욱 한국농촌건축학회 2022 농촌건축 : 한국농촌건축학회논문집 Vol.24 No.3

This study aims to find out how architectural designers applied the design process and what content is applied in the practical process of architectural design in Korea, and to improve it if there is a problem. So the study is carried out by investigating 13 architects(Including one person who wants to keep his work private) with extensive experience in architectural design. The architects were questioned on how and what content the design process was used for their representative works that had been designed. And interviews and field surveys were conducted on other matters to be improved. The survey was conducted from November 2021 to July 2022. According to the conclusion of this study, First, Most architects were applying the design process in the architectural design practice. These are caused by an impact on education, but there was also an aspect of preparation in terms of guidelines such as the Architects Association and storage rights. Second, Although the design process differed in each name and phase, it was generally carried out in the order of the start phase, the planning work phase, the basic design phase, the intermediate design phase, the implementation quarterly, and construction. Third, The step-by-step work of the design process differed slightly depending on the architect, but counseling and contract work were mainly performed at the start-up phase, and field surveys, legal investigations, and case studys were conducted at the planning phase. In the basic design phase, some contents related to architectural programming, basic drawings, images, and models were used as main work contents. In the intermediate design phase, secondary contents such as licensed books and facility facilities were the main tasks. In the implementation design phase, detailed maps and various frost facilities were finally inspected. Since then, construction and supervision have been carried out in the order of progress. Forth, As for the contents to be improved in the future, the architect's ability, the designer's knowledge of the overall architecture, the design supervision system, and the expansion of time for the initial design process were answered.

Skin Wound Healing Effects and Action Mechanism of Acai Berry Water Extracts

강미현,최승혜,김배환 한국독성학회 2017 Toxicological Research Vol.33 No.2

The purpose of this study was to investigate the wound healing effect of acai berry water extracts (ABWE) and a possible underlying mechanism involved in its action using various in vitro and in vivo models. The wound healing effect of ABWE was evaluated by migration assay using HS68 fibroblast cells. In addition, its effect on mRNA expression of procollagen, fibronectin, and MMP-1 was determined. Moreover, the wound healing effect of ABWE was evaluated in in vivo wound models through macroscopic and microscopic observation. In addition, mRNA expression levels of wound related genes were determined. Results revealed that ABWE was not cytotoxic. It increased migration of HS68 fibroblast cells. ABWE increased mRNA expression levels of fibronectin but decreased the mRNA expression levels of MMP-1. ABWE also showed significantly potent wound healing effect in vivo based on macroscopic and histopathological observation and mRNA expression evaluation for wound related genes. Taken together, our results indicated that ABWE might have potential as a wound healing agent.

비스마르크시대 식민주의 이데올로그들의 활동과 영향

강미현 동선사학회 1997 성신사학 Vol.14ㆍ15 No.-

회원작품 - 꿈을 꾸는 가(家)

강미현,Kang, Mihyeon 대한건축사협회 2021 建築士 Vol.627 No.-