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        21세기 지식기반 사업을 벤처디자인 전문회사 창업시뮬레이션 연구 : Centering around the Case of the Establishment of a Venture Enterprise, KDI(Kim, Kyung-Hun Design Institute) 벤처기업 KDI(김경훈디자인연구소) 창업 사례를 중심으로

        김경훈 한국비쥬얼디자인학회 1999 한국디자인포럼 Vol.4 No.-

        In the 21st century knowledge-and-information-oriented age, individual diversity is emphasized, and information acquisition and consumption levels are heightened. This trend of the times refuses to accept the mass production system centering around the competition in price. In consequence, inevitably does come the age of value created in which quality goods are produced by the multikind and small quantitiy production system. Design along with information and communication as 21st century knowledge-based business is gaining ground as a main factor national competitiveness is dependent upon in this age. Accordingly, the purpose of this study is to analyze the process and realities of the establishment of a firm specialized in venture design, both one of knowledge-based business and one factor which decides whether in the knowledge-and-information-oriented age, the millennium, our country will gain ground as one of the leading countries in the world or it will set in the west just like the twilight of the 20th century, and try to pave the way to promote the establishment of design venture required by this age. In a knowledge-based economic society, working methods are more important than working hours, and technical knowledge is more important than general knowledge. Desire for self-achievement is to be stronger than unilateral sense of loyalty to an organization. For the country in which there are many men of great originality who can enhance value added through incessant self-improvement, self-development and self -reformation can secure competitiveness among nations in the upcoming century.

      • KCI등재

        Mechanical Antiallodynic Effect of Intrathecal Nefopam in a Rat Neuropathic Pain Model

        김경훈,변경조,김희영,백승훈,신상욱,구성태 대한의학회 2015 Journal of Korean medical science Vol.30 No.8

        Nefopam has a pharmacologic profile distinct from that of opioids or other antiinflammatory drugs. Several recent studies demonstrate that nefopam has a mechanism of action similar to those of anti-depressants and anticonvulsants for treating neuropathic pain. The present study investigates the mechanical antiallodynic effect of nefopam using immunohistochemical study and western blot analysis in a rat neuropathic pain model. Twenty-eight male Sprague-Dawley rats were subjected to left fifth lumbar (L5) spinal nerve ligation and intrathecal catheter implantation, procedures which were not performed on the 7 male Sprague-Dawley rats in the sham surgery group (group S). Nefopam, either 10 or 100 μg/kg (group N10 or N100, respectively), and normal saline (group C) were intrathecally administered into the catheter every day for 14 days. The mechanical allodynic threshold of intrathecal nefopam was measured using a dynamic plantar aesthesiometer. Immunohistochemistry targeting cluster of differentiation molecule 11b (CD11b) and glial fibrillary acidic protein (GFAP) was performed on the harvested spinal cord at the level of L5. Extracellular signal-regulated kinase 1/2 (ERK 1/2) and cyclic adenosine monophosphate response element binding protein (CREB) were measured using western blot analysis. The N10 and N100 groups showed improved mechanical allodynic threshold, reduced CD11b and GFAP expression, and attenuated ERK 1/2 and CREB in the affected L5 spinal cord. In conclusion, intrathecal nefopam reduced mechanical allodynia in a rat neuropathic pain model. Its mechanical antiallodynic effect is associated with inhibition of glial activation and suppression of the transcription factors’ mitogen-activated protein kinases in the spinal cord.

      • KCI등재

        국산밀 품질 향상을 위한 지역별 재배 현황 및 원맥 특성 평가 2 : 농가 수집 원맥 특성 평가

        김경훈,강천식,서용원,우선희,허무룡,추병길,이춘기,박광근,박철수 韓國作物學會 2013 한국작물학회지 Vol.58 No.3

        국산밀을 재배하는 전국 175농가를 대상으로 2년 동안 농업형질과 원맥 특성을 조사 한 결과, 간장, 수장, 경수와이형주율은 년차간 차이를 나타내었다. 시비량이 많았던 남부지역에서 재배된 밀의 간장이 중북부 지역 보다 길었으며, 추비시기는 간장에 영향이 없었지만, 3월 중순 이후에늦게 추비를 준 농가의 수장은 다른 농가에 비하여 길었으나 경수는 감소하였다. 추비 횟수는 농업형질에 영향을 미치지 않는 것으로 나타났다. 농업형질과 마찬가지로 원맥특성도 연차간 변이가 있었으며, 남부지역에서 재배된 밀은중북부지역에서 재배된 밀에 비하여 천립중이 높았으며, 리터중은 낮았으며, 전라북도는 다른 지역에 비하여 낮은 회분 함량과 높은 단백질 함량을 나타냈으며, 전라남도는 다른 지역에 비하여 높은 회분 함량을 나타내었다. 추비시기가 리터중에는 영향을 주었지만 천립중과 회분 및 단백질함량에는 영향을 주지 않았으며, 추비 횟수도 원맥 특성에영향이 없는 것으로 나타났다. 시비량에 따라 간장이 증가하고, 천립중과 단백질 함량이 증가하였으며, 수장과 회분함량은 시비량과 부의 상관을 나타내었다. 단백질 함량은천립중과 정의 상관을 나타내었지만 회분 함량은 천립중 및리터중과 부의 상관을 나타내었다. 간장이 증가할수록 천립중은 증가하고 리터중은 감소하였으며, 수장은 천립중과 부의 상관을 나타내었다. 시비량이 간장 및 원맥 특성에 영향을 미치기 때문에 품종별 용도에 맞는 밀 품종을 재배하기위해서는 적정 시비기술에 대한 농가 지도가 필요하다. 또한, 국산 밀의 생산성 증진과 품질 향상 및 균일성 확보를위해서는 용도별 가공적성에 적합한 품종에 대한 집단 재배단지를 조성하고 철저한 생산 관리와 체계적인 수확 후 관리 구축에 대한 종합적인 고려가 있어야 할 것이다. Agronomic characteristics and grain properties of Korean wheat of 175 farmers in nationwide for two years, 2010/2011 and 2011/2012, were evaluated to support basic data for improving grain quality of Korean wheat and enhancing Korean wheat consumption. Agronomic characteristics, including culm length, spike length, number of spike/m 2 and rate of off-type plant, and grain properties, including 1000 kernel weight, test weight, moisture, ash and protein content, were influenced by year and location. Number of spike/m 2 , test weight, moisture, ash and protein content of wheat cultivated in 2011 were higher than those of 2012 and culm length, spike length, rate of off-type plant and 1000 kernel weight of 2012 were higher than those of 2011. Wheat cultivated in southern part of Korea showed higher culm length and 1000 kernel weight and lower test weight than those of northern part of Korea. Spike length, number of spike/m 2 and test weight were reduced by additional fertilization after mid of March, although there was no significant difference between date of additional fertilization and grain properties. Cultivated wheats in Jeollabuk-do showed lower ash content and higher protein content than those of other provinces and cultivated wheats in Jeollanam-do exhibited higher ash content than that of other provinces. As amount of fertilization increased, culm length, 1000 kernel weight and protein content increased and spike length and ash content were decreased, although date of additional fertilization did not effect on agronomic characteristics and grain properties. Amount of fertilization was positively correlated with 1000 kernel weight and protein content (r = 0.159, P < 0.05 and r = 0.212, P < 0.01, respectively) and was negatively correlated with ash content (r = -0.185, P < 0.05). Thousand kernel weight was negatively correlated with ash content (r = -0.226, P < 0.01) and positively correlated with protein content (r = 0.207, P < 0.01). Ash content increased as test weight and culm length decreased and 1000 kernel weight was influenced by culm and spike length (r = 0.397, P < 0.001 and r = -0.205, P < 0.01, respectively).

      • 터어보機械 回轉翼에서 亂動後流의 數値解析

        金炅勳,安光憲 慶熙大學校 1983 論文集 Vol.12 No.-

        The wakes of turbomachinery rotor blade are turbulent, three dimensional, and are subjected to curvature and rotation effects. The objective of this study is to predict the development of such wakes and compare the predictions with the existing data. A finite difference precedure in employed in the numerical analysis of the wake utilizing the continuity, momentum, and turbulence closure equation in the rotating curvilinear and non-orthogonal coordinate system. The effects of curvature and rotation on the turbulence structure are accounted for with this turbulence closure model. The predictions from the present turbulence model agree well with the mean velocity and the turbulence wake data.

      • 軸流流體機械의 性能向上에 關한 基礎的 硏究(Ⅰ)

        金鍾億,金炅勳 弘益大學校 1984 弘大論叢 Vol.16 No.2

        This paper reports the measurement and prediction of the three dimensional flow field in the turbomachinery passage operating with air as the test medium. The experimental investigations included measurement of the three components of mean velocity, turbulent characteristics at locations inside the turbomachinery passage utilizing a X type hot-wire probe connected to a scanning pulse generator, data-recorder, an analog digital convertor and a microcomputer. Analytical investigations were used the equation of the three dimensional inviscid flow.

      • 鉛直圓柱에서의 飽和蒸氣의 層流 膜凝縮의 線形安定理論

        金京勳 金烏工科大學校 1984 論文集 Vol.5 No.-

        The linear of laminar film condensation along inner or outer surface of a vertical tube of circular section is considered. An analytical expression for neutral stability curve is derived for infinitesimal sinusoidal disturbances of long wavelength on the basic steady flow. Results indicate that the interfacial of mass and heat tends to stabilize the flow but the curvature effect destabilizes.

      • 포텐샬 모델에 의한 저에너지에서의 C(α,γ)O 반응분석

        김병택,김경훈 順天大學校 1991 論文集 Vol.10 No.1

        The radiative capture reaction has been analyzed using the one dimensional potential model on the basis of the direct capture mechanism. We calculated the phase sifts of p- and d-wave and the astrophysical S factors of E1 and E2 transition at low energies using this model. We could have seen that the calculated phase shifts agree well with the experimental values. Otherwise the behavior of the astrophysical S factors of E1 transition at low energies didn't coincide very well with the experimental one, which would be improved by the radiative capture theory for te deformed nuclei using the two dimensional potential model.

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