사람 腦를 使用한 Thromboplastin 製造에 關한 實驗的 硏究

鄭在泓,宋文源 계명대학교 醫科大學 病理學敎室同門會 1987 樂山 鄭在泓 敎授 頌喜 紀念論文集 Vol.S No.-

1. The author has tried to prepare a standard thromboplastin for the determination of prothrombin time utilizing relatively fresh child human brain obtained at the time of autopsy, through acetone treatment. 2. A 13. 5 second thromboplastin extract, slightly slower than. the 12 second commercially available Difco product, was successfully prepared. 3. No influence on prothrombin time is’ noted when the thromboplastin solution is extracted from the powdered thromboplastin at the temperature, between 45 0C and 550 C. However, definite prolongation is observed when the extraction is made at above 600 C. 4. It appears that the optimal concentrations of powdered thromboplastin for the preparation of thromboplastin solution lie between 300 mg and 500 mg. 5. An attempt was made to prepare a slower acting thromboplastin sensitive at the level of therapeutic range, using rabbit brain and lung extract in equal parts, with uncertain success. 6. It is felt that the prospect of preparing a satisfactory fast acting standard thromboplastin is good, judging from the knowledge acquired through this experimentation. At this time, .however, we are unable to draw any specific conc1usion concerning the preparation of a sensitive slower acting thromboplastin from the rabbit.

血中 Ammonia 微量定量에 있어서 pH 및 Alkali 媒劑가 測定値에 미치는 影響에 對한 硏究

鄭在泓 계명대학교 醫科大學 病理學敎室同門會 1987 樂山 鄭在泓 敎授 頌喜 紀念論文集 Vol.S No.-

An attempt was made to determine the origin of artifactual blood ammonia formed in the shed blood; Experimentation, with blood specimens from more than 400 healthy individuals, was carried out over a period of four and a half years, utilizing two popular microdiffusion blood ammonia methods, those of Seligson and Conway. The actions of several alkali [pstassium carbonate, carbonate-bicarbonate mixture and borate-sodium hydroxide (with a pH of 9 to 11.4)] were compared by placing them in the diffusion apparatus with specimens of blood. It was found that the ammonia concentration tended to be higher with increasing pH and vice versa lowering with decreasing pH. While occasional extremely implausible results were obtained in experiments using the potassium carbonate and carbonate-bicarbonate mixture, on the other hand, no such aberrations were observed with borate-sodium hydroxide. Within the pH range, from 9 to 10.1, the yield of ammonia when plotted against the pH of the blood-alkali mixture showed a straight line. Increasing beyond 10, resulted in an asymptomatic character of diffusion curve. For these reasons, borate-sodium hydroxide reagent which results in a pH of 10.1 in the presence of blood, is selected as the choice of weak alkali media for the determination of true blood ammonia. The author has to abandon his earlier thought that aberrations in ammonia analyses can be largely attributed to faulty technique in collecting and handling blood. Careful control of these techniques resulted in some lowering of the ammonia concentration, but failed to prevent the more serious aberrations encountered. In search for clarification of the origin of extra ammonia, studies were carried out by experimenting with glutamine, both in aqueous solutions and following mixture with blood. The results suggest that non-protein glutamine is an unlikely source of extra ammonia. The only other plausible source of the extra ammonia liberated from blood, therefore, seemed to be the blood proteins, Accordingly, the action of various alkaline reagents on plasma albumin, globulin and on whole blood was tested, after prolonged dialysis to remove preformed ammonia. Ammonia was released from each of the protein solutions used. However, the action of borate in this release was less pronounced than that of the carbonate-bicarbonate mixture. This latter mixture, in turn, liberated substantially less ammonia than did potassium carbonate. Therefore, it is concluded that the origin of artifactual ammonia may be traced to the decomposition of protein by the action of alkali. The author has revised the method of measuring blood ammonia in such a way as to avoid spontaneous production of ammonia from blood proteins. The technique involves the use of sodium borate buffer at a pH of 10.8±0.2, which, when mixed with blood, results in a pH of 10.1 The adequacy of this technic is well proven by the satisfactory results obtained in a large number of recovery studies. The technique described, applied to venous specimens that were collected in EDTA tubes and promptly analyzed, was used to study a group of 16 healthy persons, 20 to 25, male, with no history of previous liver involvement. The mean blood ammonia was 0.42 μg./ml. expressed as N. The lowest value was 0.21, the highest, 0.61, with standard deviation of ± 0.124.

정확한 환자 확인을 위한 의료생체인식기술

정재홍,이경배 대한자기공명기술학회 2022 대한자기공명기술학회지 Vol.32 No.1

This study discusses medical biometrics for accurate patient identification in the medical field. It first provides information concerning the definition, classification, and types of biometrics. It then reviews recent relevant research regarding information technology and types of medical biometric recognition technology that use biological signal and medical imaging. Finally, the current status of the medical environment is examined, along with the types of biometrics applied in medical fields. We believe that medical biometrics for patient identification will be gradually introduced into the medical field. Our study can be used to understand medical biometrics for accurate patient identification and utilized as primary data for research.

칼슘의 첨가에 따른 라면의 조직감과 관능적 특성

정재홍 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.3

칼슘의 첨가가 밀가루의 아밀로그래프에한 호화 성질과 파리노그래프에 의한 반죽 성질을 조사하였고, 칼슘을 첨가하여 제조한 라면의 조직감과 관능적 특성에 미치는 영향을 검토하기 위하여 밀가루에 대하여 1.0%∼3.0%를 사용하여 라면을 제조한 뒤 면의 조직 특성, 조리시험을 측정하고 관능검사를 평가하였다. 칼슘의 첨가는 아밀로그래프의 호화개시 온도를 지연시켰으며, 최고 점도를 감소시켰다. 패리노그래프의 흡수율과 반죽의 안정도는 칼슘의 첨가에 의해 증가되었다. 칼슘을 첨가하여 제조한 라면의 층밀림 압출력과 경도는 대조구보다 높게 측정되었다. 3.0%의 칼슘을 첨가하여 제조한 라면의 무게 증가는 대조구 보다 높게 나타났으나, 부피 증가는 오히려 낮게 나타났다. 용출량의 변화는 칼슘의 첨가량에 따라 약간 감소하는 경향을 보였다. 요오드 정색도는 모든 시료가 2.12∼2.22으로 유사하게 나타났다. 칼슘을 첨가하여 제조한 라면의 관능 검사 결과는 비교적 좋은 점수를 얻었다. 이 결과에서 알 수 있듯이 라면 제조시 칼슘의 첨가량은 3.0%의 수준이 효과가 큰 것으로 평가되었다. In an attempt to evaluate the effects of calcium on paste or gelatinization properties by amylograph and mixing properties by farinograph of wheat flour, and on viscosity property, cooking quality, textural and sensory properties of Ramyon were examined. The contents of calcium used were from 1.0% to 3.0% based on flour weight. The viscosity property of wheat flour with calcium was increased the initial pasting temperature but the amylograph peak viscosity were decreased in vice versa. The farinography absorption, stability and breakdown were increased by calcium. The shear extrusion force and hardness of Ramyon manufactured with calcium were shown much higher value than those of control. At cooking quality examination of Ramyon manufactured with calcium, weight of cooked Ramyon was increased but volume was decreased . Extraction amounts of Ramyon manufactured with calcium during cooking were much smaller than those of control. These changes will provided many advantages in the preparation of Ramyon. The I_2 reaction value of Ramyon manufactured with calcium and control were shown to almost same values. Sensory properties of cooked Ramyon which was manufactured with calcium showed quite acceptable. Based on the cooking and sensory evaluation test, addition of 3.0% calcim to wheat flour may be suitable for processing Ramyon.

타액선에 생긴 점막표피 암종 2예 보고

김선영,채종민,정재홍 啓明大學校 醫科大學 1986 계명의대학술지 Vol.5 No.1

Mucoepidermoid carcinoma is characterized by the presence of squamous cells, mucus-secreting cells and cells of intermediate type. And degree of histologic differentiation is highly important prognostically. The grading used is : low, intermediate and high degree. However, appropriate terminology and classification for the mucoepidermoid carcinoma and clinical behavior together the criteria for histological grading have continued to be controversial. Recently, the authors experienced two cases of mucoepidermoid carcinoma, intermediate degree, in the right parotid gland and right submandibular gland. Herein, we are presenting our experiences and literatures are reviewed.

家兎의 創傷에 塗布한 各種 Biological Dressing의 比較觀察

李悳熙,河芝耘,李永吉,姜振聲,鄭在泓 大韓成形外科學會 1979 Archives of Plastic Surgery Vol.6 No.1

The principal objectives of treating open infected wound or burns are the early removal of necrotic tissue and adequate wound coverage constituting variable methods of temporary biological dressings. Temporary biological dressings are essential and life saving for large skin defects until permanent repair with autografts or isograft can be instituted. Since early times, several attempts of variable temporary biological dressings were used for wound coverage which included allografts and xenografts, some successful, some unsuccessful. We used healthy rabbits in the study of comparing biological dressings. The backs of 20 rabbits were shaved and each rabbit had 6 wounds measuring 3×3cm. The rabbit were divided into 2 groups, group Ⅰ had split thickness defects and group Ⅱ had full thickness skin defects. By using aseptic technique, through an abdominal incision, rabbit amniotic membrane was obtained from the placenta, the membrane was cleansed with sterile isotonic saline solution and 0.025% sodium hypochlorite solution for sterilization prior to being applied on each wound. Human amniotic membrane was obtained from placenta by easily peeling it from the chorion and was prepared by the same method as the rabbit amniotic membrane.

Relevant Reduction Effect with a Modified Thermoplastic Mask of Rotational Error for Glottic Cancer in IMRT

정재홍,정주영,조광환,류미령,배선현,문성권,김용호,최보영,서태석 한국물리학회 2017 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.70 No.3

The purpose of this study was to analyze the glottis rotational error (GRE) by using a thermoplastic mask for patients with the glottic cancer undergoing intensity-modulated radiation therapy (IMRT). We selected 20 patients with glottic cancer who had received IMRT by using the tomotherapy. The image modalities with both kilovoltage computed tomography (planning kVCT) and megavoltage CT (daily MVCT) images were used for evaluating the error. Six anatomical landmarks in the image were defined to evaluate a correlation between the absolute GRE () and the length of contact with the underlying skin of the patient by the mask (mask, mm). We also statistically analyzed the results by using the Pearson’s correlation coefficient and a linear regression analysis (P < 0.05). The mask and the absolute GRE were verified to have a statistical correlation (P < 0.01). We found a statistical significance for each parameter in the linear regression analysis (mask versus absolute roll: P = 0.004 [P < 0.05]; mask versus 3D-error: P = 0.000 [P < 0.05]). The range of the 3D-errors with contact by the mask was from 1.2% - 39.7% between the maximumand no-contact case in this study. A thermoplastic mask with a tight, increased contact area may possibly contribute to the uncertainty of the reproducibility as a variation of the absolute GRE. Thus, we suggest that a modified mask, such as one that covers only the glottis area, can significantly reduce the patients’ setup errors during the treatment.

Flash를 활용한 자연과 WBI의 설계 및 구현

정재홍,한상태,이철환 한국스쿨넷학회 2000 학술발표 논문집 Vol.2000 No.1

광학적 기법에 의한 Frost 두께 측정방법의 개발 ( Development of Frost Thickness Measurement Method Using Optical Technique )

정재홍,윤상열,김경천 대한기계학회 2001 대한기계학회 춘추학술대회 Vol.1 No.4

사람腦를 使用한 Thromboplastin 製造에 關한 實驗的 硏究

鄭在泓,宋文源 최신의학사 1963 最新醫學 Vol.6 No.6