BDB, 탄닌산 및 트립신處置赤血球를 使用한 E1 tor vibrio의 血球凝集反應에 關한 硏究 : BDB, 탄닌산 및 트립신처치적혈구를 사용한 E1 tor vibrio의 혈구응집반응에 관한 연구

박수연 부산의대 1973 부산의대잡지 - 부산대학교 의과대학 Vol.13 No.1

밸런스 운동이 경도인지장애 여성 노인의 인지기능 및 신체기능에 미치는 영향

박수연 한국스포츠학회 2022 한국스포츠학회지 Vol.20 No.3

This study was conducted to investigate the effect of balance exercise on cognitive and physical functions of elderly women with mild cognitive impairment for 12 weeks. The Subjects who participated in the study (67.76±6.32yr; n=24) were only those who were found to have mild factor disorder using the Montreal Cognitive Assessment-Korean (MoCA-K) Korean version. The balance exercise conducted in this study was divided into balance aerobic exercise and balance resistance exercise for 12 weeks and exercise intensity and exercise time were programmed by applying the principle of incremental load and considering the characteristics of elderly women with mild cognitive impairment. Significant differences were found in weight and BMI factors according to the balance exercise for 12 weeks, and significantly differences were found as a results of a cognitive evaluation test using MoCA-K. Also, a significant improvement effect was found in the general posture factor among the factors of the balance test, and a significantly improved result was also shown in the chair standing test. Based on these results, it was found that balance exercise for 12 weeks can have a positive effect on the cognitive and physical functions of elderly women with mild cognitive impairment. 이 연구는 경도인지 장애를 가진 노인 여성을 대상으로 12주간의 밸런스 운동을 진행하여 밸런스 운동에 따른 인지기능과 신체 기능에 미치는 효과성을 알아보고자 실시되었다. 연구에 참여한 연구대상자(67.76±6.32세; n=24)는 한국판 몬트리올 인지평가 (Montreal Cognitive Assessment-Korean: MoCA-K)로 경도인자 장애로 판명된 대상자만을 대상으로 하였다. 이 연구에서 진행한 밸런스 운동은 밸런스 유산소성 운동과 밸런스 저항성 운동으로 구분하여 12주간 진행되었으며, 운동 강도와 운동 시간은 점증부하의 원리를 적용하고 경도인지장애를 가진 노인 여성의 특성을 고려하여 밸런스 운동프로그램을 진행하였다. 12주간의 밸런스 운동에 따른 체중과 BMI 요인에서 유의한 차이가 나타났고, MoCA-K를 활용한 인지 평가검사 결과 유의한 차이가 나타났다. 또한, 균형검사 요인 중 일반자세 요인에서 유의한 향상 효과가 나타났고, 하체 근력 및 근지구력 검사(의자 일어서기)에서도 유의하게 향상된 결과를 보였다. 이러한 결과를 토대로 12주간의 밸런스 운동이 경도인지 장애를 가진 노인여성의 인지기능 및 신체기능에 긍정적인 효과성이 발현될 수 있음을 알 수 있었다.

혈액투석 환자에서 혈행을 통한 파종성 감염으로 발생한 칸디다 관절염 1예

박수연,권용환,김석원,장동원,정연오,손민수,차란희 대한노인병학회 2014 Annals of geriatric medicine and research Vol.18 No.2

Candida is a rare cause of infectious arthritis, and it can be found in infants and immunocompromised patients. Patients with maintenance hemodialysis are prone to opportunistic infections because of altered immunity, and frequent exposures to health-care associated infections. Herein, we report a case of candida arthritis of right shoulder with precedingfungemia in patients with maintenance hemodialysis. The diagnosis is based on the isolation of Candida Tropicalis from blood and synovial fluids of the shoulder joint. The patient has received intravenous fluconazole and arthroscopic surgical debridement. We then changed the fluconazole into amphotericin B due to the abnormal signs in the liver function tests, although the fluconazole successfully controlled fungemia and arthritis. To the best of our knowledge, this is the first case of candida arthritis in patients with maintenance hemodialysis in South Korea.

[작품론] ‘고요’를 읽다

박수연 천년의시작 2018 (계간)시작 Vol.17 No.2

간행위원회에 보내는 글 : 클립을 이용한 교감신경 차단술이 자율신경계 기능에 미치는 영향

박수연,안원식 대한마취과학회 2006 Korean Journal of Anesthesiology Vol.51 No.1

3D 체표면 변화분석과 동작적합성에 따른 여성 로드바이크웨어 하의 패턴 설계 연구

박수연,김경희 한복문화학회 2019 韓服文化 Vol.22 No.3

현재 우리나라는 대체 휴일과 주 5일 근무제가 시행되면서 여가를 즐기는 사람들의 수도 늘어나면서 사이클을 즐기는 클럽과 동호인 수는 해마다 증가하고 있다. 국내 스포츠웨어 및 아웃도어 업계에서는 자전거 의류라인을 출시하며 사이클 전문 스포츠웨어 브랜드를 런칭하고 있는 추세이다. 이러한 문화 현상에 따라 성별 및 연령에 따른 보다 전문적인 의복 생산이 시급하며 국내 바이크웨어 시장이 확대되어 가는 시점에서 주행동작에 따른 신체 변화를 고려한 기능적인 의복 패턴 설계가 필요하다. 연구 방법은 로드바이크 주행자 중에서 30∼34세 여성을 대상으로 예비조사를 실시한 후, 바이크웨어의 현재 착용 브랜드 및 하의 선호도와 불편사항 등을 파악하였다. 또한 로드바이크 라이딩 경력이 1년 이상인 사람 중에서 기술표준원이 제시한 30∼34세 성인여성 표준체형의 오차범위 내에 해당하는 피험자를 선정하였다. 각 피험자는 A, B, C, D 4종의 비교복을 착용한 상태에서 정자세와 바이크에 올라타는 자세를 비롯한 로드바이크 주행자세를 각각 5분간 실시하여 평가 결과가 가장 우수한 비교복의 패턴을 기본 패턴으로 사용하였다. 또한, 선정된 기본패턴을 수정, 보완하여 실험복을 제작하였고 3D 스캔 데이터와 동작분석을 통하여 각 부위의 신장 및 수축을 고려하여 기본 패턴의 절개라인과 식서방향, 패턴의 구조 등을 변형한 실험복을 제작하였다. 실험복에 대한 평가는 동작적합성 평가로 패턴의 적합성 여부를 검증하였고, 뇌파 분석을 통하여 쾌적성이 우수함을 증명하였다. 본 연구는 이상의 결과를 바탕으로 로드바이크의 주행동작에 따른 운동적합성과 맞음새가 우수한 로드바이크웨어 하의 패턴을 제시함으로써 보다 세분화되고 전문적인 스포츠웨어 시장이 성장할 수 있는 패턴 설계에 대한 기초자료를 제공하고자 한다 The alternative holidays and 5-day workweek have contributed to the increase in the number of people who enjoy cycling leisure life such as joining the sports clubs every year. Therefore, domestic sports and outdoor industry have rushed to launch cycling clothing lines with new brands specializing in cycling sportswear. This rapid change Also, an increasing number of female bike riders as part of their leisure life has boosted the sales of cycling wear and gear. In this research, adult females who were aged 30 to 34 and enjoy riding road bikes were surveyed as part of a preliminary study to find out about their cycling clothing brands, preference for cycling pants, and complaints. Among those who had been riding road bikes for at least a year, 3 subjects whose body types corresponded to the standard for women aged 30 to 34 prescribed by the Korean Agency for Technology and Standards within the margin of error were selected. Based on the results of the preceding studies, the present study measured 3D scan data to determine the variation in the body surface for each motion of the subjects riding road bikes. Next, the subjects put on the selected comparison wears A, B, C, and D, and performed basic cycling motions for five minutes to compare the clothing samples, where the best rated pattern was selected and used as the basic pattern. In addition, based on the extension and contraction of each body part found in the analysis of body surface, the cutting lines, selvage and structure of the basic pattern were transformed to make a pair of experimental pants for cycling. The first mobility test and the second EEG analysis found the final pattern fitted and showed the best performance. The proposed pattern for road cycling pants offers superior mobility and fits well on the body. The present findings provide some reference data conducive to the growth of more segmented and specialized sports wear market and the healthier leisure life of women.

갑상선기능저하증 환자 一例에 관한 臨床報告

박수연,김홍진,김종한,최정화,Park, Su-Yeon,Kim, Hong-Jin,Kim, Jong-Han,Choi, Jung-Hwa 대한한방안이비인후피부과학회 2001 한방안이비인후피부과학회지 Vol.14 No.2

I researched clinically one patient with Hypothyroidism who was hospitalized in DongShin Univ Shunchun Oriental Hosp. from the 4th, November, 2000 to the 13th, December, 2000. The results were obtained as follows. 1. Hypothyroidism corresponds to edema of instep (浮腫), consumption (虛勞), infantile retardation of walking (行遲), retardation in speech (語遲), inactivity of Yang-Qi(결양증). It is caused to deficiency of both Qi and blood (氣血兩虛), insufficiency of Yang of the spleen and kidneys (脾腎陽虛), decline of the fire from the vital gate (命門火衰), deficiency of yang of the heart and kidneys (心腎陽虛) 2. In internal medication, it was thought that Yi qi bu xue tang(益氣補血湯). Shao yin ren Bu zhong yi qi tang(少陰人補中益氣湯), Jia wei ta bu tang (加味大補湯) were effective. 3. In acupunture therapy, zu san li(足三里), san yin jiao(三陰交), Ren ying (人迎), Fu tu (扶突), Tian tu(天突) were used frequently and in moxibustion therapy. qi hai(氣海), zhong wan(中脘). Guan yun(關元) were used for Hypothyroidism.

전립선암 치료를 위한 세기조절 양성자 로버스트 치료계획

박수연,김종식,박주영,박원,주상규,Park, Su Yeon,Kim, Jong Sik,Park, Ju Young,Park, Won,Ju, Sang Gyu 대한방사선치료학회 2013 대한방사선치료학회지 Vol.25 No.1

목 적: 양성자선의 유효비정 변화와 환자 자세의 재현성을 고려한 로버스트(robust-IMPT) 세기조절양성치료와 플레인 세기조절양성자치료(plain-IMPT) 계획과 광자선 세기조절방사선치료(photon-IMRT, step & shoot) 계획의 선량분포 특성을 비교, 분석하고자 한다. 대상 및 방법: 다섯 명의 전립선암 환자를 대상으로 표적에 70 Gy를 조사하도록 photon-IMRT (7문, step & shoot)와 plain-IMPT (2문, 4문, 7문) 및 robust-IMPT (유효 비정 오차 ${\pm}5%$ & 환자 자세 오차 0.5 cm 적용) 치료계획을 수립했다. 세 가지 치료계획으로 얻은 선량 분포 비교를 위해 PTV에 대한 선량조형지수(Conformity Index, CI), 선량균등지수(Homogeneity Index, HI) 및 최대선량, 최소선량, 평균선량과 OAR에 대한 선량-체적을 평가했다. 결 과: 모든 환자에 대해 photon-IMRT, plain-IMPT, robust-IMPT에서 PTV의 평균 최대선량은 각각 76.75 Gy (109.6%), 71.92 Gy (102.7%), 72.09 Gy (103%)였으며, 평균 최소선량은 68.21 Gy (97.4%), 68.89 Gy (98.42%), 68.13 Gy (98.13%)였으며, 전체 평균선량은 각각 71.02 Gy (101.4%), 71.32 Gy (100.4%), 70.75 Gy (101%)였다. PTV에 대한 CI 및 HI 값은 plain-IMPT가 photon-IMRT와 robust-IMPT에 비하여 1.02, 1.00으로 가장 낮았다. 또한, 정상장기에 있어 plain-IMPT가 photon-IMRT에 비하여 대부분 낮은 선량 분포를 보였으며, robust-IMPT 적용 시 정상 장기에 대한 선량 분포가 다소 변동의 폭은 있었지만 photon-IMRT에 비하여 대체로 낮은 선량 분포를 보였다. 결 론: 전립선암의 IMPT 치료 시 정확한 유효비정의 오차와 환자 자세 재현성오차를 고려한 robust-IMPT를 적용한다면 plain-IMPT의 선량학적 불확도를 줄이고 photon-IMRT에 비해 효과적인 치료를 제공할 수 있을 것이다. Purpose: The aim of this study is to evaluate the dosimetric properties of robust planning strategy for plain intensity-modulated proton therapy (IMPT) taking into account of the uncertainties of effective proton range and set up error as compared to photon intensity-modulated radiation therapy (photon-IMRT) in prostate cancer treatment. Materials and Methods: The photon-IMRT (7 beams, step & shoot), plain-IMPT (2, 4, and 7 portals), and robust- IMPT plans, which was recalculated the plain-IMPT based on the uncertainties of range error (${\pm}5%$) and set up error (0.5 cm), were evaluated for five prostate cancer patients prescribed by 70 Gy/35 fractions. To quantitatively evaluate the dose distributions, several parameters such as maximum dose, minimum dose, mean dose, conformity index (CI), and homogeneity index (HI) for PTV as well as dose-volume index of VxGy for OARs were calculated from dose-volume histograms. Results: Robust-IMPT showed superior dose distributios in the PTV and OARs as compared to plain-IMPT and photon-IMRT. Like plain-IMPT, robust-IMPT were resulted in dose fluctuation around OARs, while better homogeneity and conformity in PTVs and lower mean dose in OARs as compared to photon-IMRT. Conclusion: In consideration with the effective range correction and set up movement using robustness in IMPT plan, the dosimetric uncertainties from plain-IMPT could substantially reduce and suggest more effective solutions than photon-IMRT in prostate cancer treatment.

마우스肝 構造에 對한 組織學的 및 組織化學的 硏究

朴秀淵 中央醫學社 1940 中央醫學 Vol.9 No.2

As the structural unit of the hepatic tissue, Wepfer (1664) and Malpighi (1666) termed the parenchymal units attached to the intrahepatic portal venules hepatic acini by the macroscopic dissection. Kiernan (1883) associated the three-dimensional structural unit of the liver with its secretory function. Brissaud and Sabourin (1886) reported the area of the hepatic parenchymal tissue draining into a bile duct in the portal trigone as the secretory unit of the liver. Mall (1906) proposed that the columnar structure around the portal field was the portal unit; he was supported by Arey (1932) and Opie (1944). Rappaport et al. (1954) defined the small irregular morular parenchymal tissue mass attached to the portal terminal venules accompanying with the intrahepatic arteries and bile duct in the livers of dogs and house rabbits as the structural and functional unit, of the liver, and called it the simple liver acinus. Rappaport (1958) termed the hepatic parenchymal tissue consisting of the simple liver acini around the preterminal portal vessel in man the complex acinus and the larger parenchymal tissue of the- simple liver and complex acini formed around the portal stem the acinar agglomerate. Recently the studies of the liver concerning the function of it in the histological and histochemical fields were carried out by many authors. Padykula (1953) reported that the patterns of distribution of hepatic mitochondria, Golgi apparatus and glycogen in various mammals, and the secretion of bile were associated with enzyme activity of hepatic succinic dehydrogenase in the histochemical way. Additionally he described the fact that his result was similar with them presented by Deane (1944), and Seligman and Rutenberg (1951). The technique, as presented by Wachstein and Meisel (1957), outlines bile canaliculi sharply and completely with the histochemical way of adenosine triphosphatase (ATP-ase) and diphosphatase (ADP-ase), as well as bile ducts, endothelium, and fibrous tissue, and can thus be effectively used as special stain for canaliculi, as well as an indicator of liver cell function. Smith and Coote (1863) studied the impairment of succinic dehydrogenase and other enzymes in the rat's liver given carbon tetrachloride in their histochemical study. Schumacher (1957) studied the action of respiratory enzymes; succinic dehydrogenase, cytochrome oxidase, triphosphopyridine nucleotide diaphorase and diphosphopyridine diaphorase in the livers of the horse, pig and cattle, and observed that the distribution was identical with the earlier reports on the former enzymes, but that it was in direct contrast to the former 2 enzymes in that the latter 2 enzymes were generally distributed to the pericentral area around the central vein. The author has attempted this experiment in order to study the hepatic structural and function unit of the mouse by observing the histological and histochemical or functional characters of the hepatic cells in different parts of hepatic lobule in the points; the distribution of mitochondria (2) the enzyme activity of succinic dehydrogenase (3) the enzyme activities of adenosine triphosphatase and diphosphatase, (4) the enzyme activities of diphosphopyridine nucleotide (NADH,) diaphorase and triphosphopyridine nucleotide (NADPH,) diaphorase, to accomplish the transfer of hydrogen from the reduced coenzymes to the cytochrome system and to other metabolic processes, and (5) the enzyme change of succinic dehydrogenase and histochemical change of hepatic glycogen of the mouse given carbon tetrachloride.

외벽마감재에 따른 병원건축물 배색 이미지 만족도 연구 ( A Study about a Degree of Coloring Image Satisfaction to Hospital Architecture According to Exterior Finishing Material )

박수연,박성진,이청웅 대한건축학회 2002 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.22 No.2