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Park, Jun-Young,Moon, Dong-Il,Bae, Hagyoul,Roh, Young Tak,Seol, Myeong-Lok,Lee, Byung-Hyun,Jeon, Chang-Hoon,Lee, Hee Chul,Choi, Yang-Kyu IEEE 2016 IEEE electron device letters Vol.37 No.7
<P>A shift in threshold voltage caused by total ionizing dose (TID) is problematic in the MOSFET, especially in aerospace applications. Unlike traditional methods to minimize damage from TID, in this letter, a novel electro-thermal annealing method to cure the TID-induced damage is demonstrated for the first time. In this concept, the conventional hardening or shielding techniques are not used. In a gate-all-around MOSFET structure, dual gate electrodes were employed as an embedded nanowire heater to generate localized Joule heat, which can anneal insulating layers, including gate oxide and spacer. With the Joule heat, trapped positive charges produced by the TID were neutralized within 200 ms. A damaged device with a radiation-induced threshold voltage shift was repaired to the level of a fresh pristine device.</P>
조용현 ( Yong Hyun Cho ),신광일 ( Kwang Il Shin ),김선희 ( Sun Hee Kim ),이동현 ( Dong Hyun Lee ),김형탁 ( Hyung Tak Kim ),김상인 ( Sang In Kim ),전석호 ( Seok Ho Jeon ),이현석 ( Hyun Seok Lee ) 경희대학교 경희의료원 2018 慶熙醫學 Vol.33 No.1
In this case report, we aimed to report a total spinal block, an unusual complication. Total spinal anesthesia is a well documented serious life threatening complication which results from an attempted spinal or epidural analgesia. We had an accidental total spinal anesthesia associated with a cranial nerve paralysis and an eventual unconsciousness during spinal block. We experienced successful recovery from anesthesia without any adverse effect. We report our clinical experience, including brief review of the relevant literature.
원발성 간암 환자에서 간동맥 색전술 시행 후 위십이지장 병변의 발생과 관련된 인자
김성국,조재현,정준모,최정일,최용환,전성우,권영오,탁원영,김용주,하승수,염헌규 대한소화기내시경학회 2000 Clinical Endoscopy Vol.20 No.3
Background/Aims: Gastroduodenal lesions such as erosions and ulcers are less infrequent complications after transcatheter arterial embolization (TAE) procedures. This study was conducted to clarify the incidence and associated factors of post-TAE gastroduodenal lesions. Methods: Cases involving 142 patients with unresectable hepatocellular carcinoma (HCC) who underwent TAE during 70 months were retrospectively analyzed. Endoscopic examinations were performed before and after TAE. Patients were classified into two groups depending upon whether gastroduodenal lesions developed or not. Results: New gastroduodenal lesions developed in 32 of 142 patients (22.5%) within 3 months of TAE. Of these, 14 patients (9.9%) developed upper gastrointestinal bleeding. There were no significant differences in clinical and biochemical characteristics between the two groups (p>0.05). There was also no significant difference in catheter selection level, tumor type, number of TAE, use of gelform between the two groups (p>0.05). wever, the cases involving large tumor size (>8 cm) and angiographical abnormalities of hepatic arteries including atypical branching, vascular tortuosity, spasms or intimal dissection during the procedure, infusion of embolizing materials adjacent to vessels supplying the stomach or duodenum, had more post-TAE gastroduodenal lesions. These two factors were found to significantly affect the development of post-TAE gastroduodenal lesions by multivariate analysis (p<0.05). Conclusions: The major factors associated with the development of post-TAE gastroduodenal lesions are large tumor sizes and angiographical abnormalities of hepatic arteries. Upper gastrointestinal endoscopy should be performed as follow-up examinations in these patients.
( Ahmed Abdal Dayem ),( Soo Bin Lee ),( Kyeongseok Kim ),( Kyung Min Lim ),( Tak-il Jeon ),( Ssang-goo Cho ) 생화학분자생물학회(구 한국생화학분자생물학회) 2019 BMB Reports Vol.52 No.5
Breakthroughs in stem cell technology have contributed to disease modeling and drug screening via organoid technology. Organoid are defined as three-dimensional cellular aggregations derived from adult tissues or stem cells. They recapitulate the intricate pattern and functionality of the original tissue. Insulin is secreted mainly by the pancreatic β cells. Large-scale production of insulin-secreting β cells is crucial for diabetes therapy. Here, we provide a brief overview of organoids and focus on recent advances in protocols for the generation of pancreatic islet organoids from pancreatic tissue or pluripotent stem cells for insulin secretion. The feasibility and limitations of organoid cultures derived from stem cells for insulin production will be described. As the pancreas and gut share the same embryological origin and produce insulin, we will also discuss the possible application of gut organoids for diabetes therapy. Better understanding of the challenges associated with the current protocols for organoid culture facilitates development of scalable organoid cultures for applications in biomedicine. [BMB Reports 2019; 52(5): 295-303]
정재열 ( Jae-yeol Cheong ),함세영 ( Se-yeong Hamm ),김광구 ( Kwang-koo Kim ),이충모 ( Chung-mo Lee ),전항탁 ( Hang-tak Jeon ),옥순일 ( Soon-il Ok ) 대한지질공학회 2016 지질공학 Vol.26 No.3
해안지역의 염수침입은 지하수내 다양한 지화학 성분들에 의해서 탐지될 수 있다. 그러나 불충분한 지하수 자료는 염수침입의 인지를 어렵게 한다. 확률밀도함수는 제한된 수질자료를 이용하여 더 넓은 범위의 확률적 예측이 가능하며 특성화된 확률밀도 분포 도출을 통하여 해안지역의 염수침입을 효과적으로 판단할 수 있다. 본 연구에서는 부산시의 해안지역 지하수, 해안유출수, 하천수의 화학성분에 대해서 확률통계기법을 적용함으로써 염수침입을 평가하였다. 이 연구에 의해서, 해수 중에 농도가 높은 항목인 Na+, Mg²+, K+, SO₄²-, Cl- 은 염수의 영향유무 판별의 유용한 지시자인 것으로 판명된다. 한편, 지하수, 해안유출수 및 하천수에서 유사한 확률분포형태를 보이는 항목인 Si⁴+, Fe2+, NO₃-., PO₄³-은 염수영향에 대한 지시자로서 적당하지 않은 것으로 판단된다. Saltwater intrusion in coastal regions can be detected by using numerous geochemical constituents in groundwater. However, insufficient numbers of groundwater data can often make us difficult to interpret saltwater intrusion. Probability statistics technique enables statistical prediction using a limited numbers of water quality data for a wider range and can make to effectively evaluate saltwater intrusion through a characterized distribution of probability. This study evaluated saltwater intrusion by applying probability statistics to the chemical constituents in groundwater, coastal discharge, and stream water in the coastal areas of Busan City. By the result of the study, it is proven that Na+, Mg²+, K+, SO₄²-, and Cl-, abundantly contained in seawater, are valuable indicators for evaluating saltwater intrusion. On the other hand, it is judged that Si⁴+, NO₃-, Fe2+, and , PO₄³-, showing sim-ilar probability distribution in groundwater, coastal discharge, and stream water, are not appropriate indicators for the detection of saltwater intrusion.