體力章制度의 關心度比較에 關한 調査硏究 : 馬山市 男子高等學校 進學, 比進學者를 中心으로 Comparison of advancing to higher education and onadvancing highe education for the boy high school, Masan-si

鄭民煥,李錫南,朴昌植,丁小鳳,金成根 경희대학교 체육과학연구소 1978 體育學論文集 Vol.6 No.-

In the result of the research on the interests to the physical strength code system of boy high school (Comparison) of advancing to higher education and nonadvancing to higher education), it was possible to deduce the following conclusion and the suggestions from the theoretical background and the assumptions mentioned above forwarded by this research. 1. The understanding in the system of P.S.C. in inefficient. 2. The system failed to provide to one's strengh buiding 3. The training for P.S.C. is always not practiced consistently but being exercised on the immediate of inspection. 4. The understanding on the itemized purpose of its inspection is relatively low. 5. The inspection has something to do with the entrance examination and conderned because of the directive score points. 6. The inspection system failed to show a fairness and a lot of contradictions have been pointed out in the course of its execution. 7. In a comparison of advancing to higher education and nonadvanoing to higher education, the latter has not considered a special necessity. 8. The relative importance for the entrance examination by current inspection of P.S. has shown as fitted one. 9. It is not well comed to practice only in the training of P.S.C. at the assigned time to P.S. From the above conclusion, the following suggestions are required. 1. It is required that the system of P.S.C. is to be equally alotted to the all physical curriculum so that the guidance with the possitive plans be undertaken in the ordinal time. 2. It should not be limited of the system of P.S.C. in reflecting to the result of entrance examination for the boys of advancing to higher educations, and but considered in the dimension of national aspects, and the systematic backing policy enabling to exercise with a interest to the system of P.S.C even for the group of non-advancing for higher education be necessary. 3. A objectivity making the inspection thorough and correct in the course of execution, of the system of P.S.C. is required. 4. The fairness of inspection should be maintained by a sufficient training in advance for the staffs of the physical strength inspection and the inconsistencies should be developed. 5. The items of sport(Swiming, physical exercise, shooting etc.) beside the items of current P.S. inspection is recommended to be added. In the end, by strengthening the grade of current P.S. inspection, it is necessary to let people know that it Is very hard to get a special grade without a consistent effort in ordinary day.

Towards high performance unique microstructures of Co₉S₈//CoFe₂O₄ for asymmetric supercapacitor

Patil, S.J.,Lokhande, A.C.,Park, J.S.,Kim, J.H.,Kim, Y.B.,Choi, B.C.,Park, S.H.,Jung, S.H.,Lee, D.W. Elsevier 2018 Journal of industrial and engineering chemistry Vol.61 No.-

<P><B>Abstract</B></P> <P>Herein, we have proposed asymmetric supercapacitor device to achieve empirical electrochemical performance based on binder-free Co<SUB>9</SUB>S<SUB>8</SUB> and CoFe<SUB>2</SUB>O<SUB>4</SUB> electrodes. The unique architecture and porous surface of the prepared electrodes were analyzed using electron microscopy and Brunauer–Emmett–Teller technique. Electrochemical properties of Co<SUB>9</SUB>S<SUB>8</SUB> and CoFe<SUB>2</SUB>O<SUB>4</SUB> electrode were employed in a three-electrode cell-configuration that exhibits a capacitance of 817 and 1203Fg<SUP>−1</SUP>, respectively. Co<SUB>9</SUB>S<SUB>8</SUB>//CoFe<SUB>2</SUB>O<SUB>4</SUB> asymmetric supercapacitor reveals a high capacitance of 79.11Fg<SUP>−1</SUP> with 28.88Whkg<SUP>−1</SUP> energy density and superior cyclic stability over 2500 cycles (∼87%). These results suggest that prepared electrodes have a great potential for practical applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Unique-microstructures of C<SUB>o9</SUB>S<SUB>8</SUB> and CoFe<SUB>2</SUB>O<SUB>4</SUB> electrodes were prepared. </LI> <LI> C<SUB>o9</SUB>S<SUB>8</SUB>//CoFe<SUB>2</SUB>O<SUB>4</SUB> supercapacitor exhibits an energy density of 28.88Whkg<SUP>−1</SUP>. </LI> <LI> The assembled Co<SUB>9</SUB>S<SUB>8</SUB>//CoFe<SUB>2</SUB>O<SUB>4</SUB> supercapacitor delivers a superior rate capability. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>The Ragone plot shows the electrochemical performance of the Co<SUB>9</SUB>S<SUB>8</SUB>//CoFe<SUB>2</SUB>O<SUB>4</SUB> asymmetric supercapacitor device, and inset shows the BET surface area plot.</P> <P>[DISPLAY OMISSION]</P>

Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ^ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis

Dal Rhee, S.,Kim, C.H.,Seon Park, J.,Hoon Jung, W.,Bum Park, S.,Youn Kim, H.,Hwan Bae, G.,Jan Kim, T.,Young Kim, K. North-Holland ; Elsevier Science Ltd 2012 european journal of pharmacology Vol.691 No.1

Carbenoxolone is the 3-hemisuccinate of glycyrrhetinic acid, the active principal of licorice (Glycyrrhiza glabra). It was reported that carbenoxolone improved glucose tolerance with increased insulin sensitivity in mice with high fat diet-induced obesity. In the present study, we elucidated the protective effect of carbenoxolone in fatty liver animal models of C57BL/6-Lep<SUP>ob/ob</SUP> mice through inhibition of hepatic lipogenesis and apoptosis. In addition, the potential mechanisms by which carbenoxolone could exert such protection were elucidated. Carbenoxolone was daily administrated by gavage for 28 days in C57BL/6 and C57BL/6-Lep<SUP>ob/ob</SUP> mice. Carbenoxolone prevented the plasma triglyceride and free fatty acid accumulation associated with the reduction of the expression of sterol regulatory element binding protein-1c, liver X receptor, fatty acid synthase and acethyl-CoA carboxylase in the livers of C57BL/6-Lep<SUP>ob/ob</SUP> mice. Carbenoxolone also prevented hepatic injury through anti-apoptotic action in the livers of C57BL/6-Lep<SUP>ob/ob</SUP> mice, accompanied by increased Bcl-2 expression and suppressed Bax and cytochrome c expression. As a mechanism, increased inflammatory cytokine expressions were inhibited by carbenoxolone in the fatty livers of C57BL/6-Lep<SUP>ob/ob</SUP> mice. Furthermore, carbenoxolone inhibited free fatty acid (oleate/palmitate) induced reactive oxygen species formation and reversed free fatty acid induced mitochondrial membrane depolarization in HepG2 cells. Carbenoxolone prevents the development of fatty liver by inhibiting sterol regulatory element binding protein-1c expression and activity with an anti-apoptotic mechanism via the inhibition of inflammatory cytokine and reactive oxygen species formation in the livers of C57BL/6-Lep<SUP>ob/ob</SUP> mice. It is suggested that carbenoxolone prevents the development and progression of fatty liver disease in patients with insulin resistance.

Characterization of Insertional Variation of Porcine Endogenous Retroviruses in Six Different Pig Breeds

Jung, W.Y.,Yu, S.L.,Seo, D.W.,Jung, K.C.,Cho, I.C.,Lim, H.T.,Jin, D.I.,Lee, Jun-Heon Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.10

Pigs may need to be exploited as xenotransplantation donors due to the shortage of human organs, tissues and cells. Porcine endogenous retroviruses (PERVs) are a significant obstacle to xenotransplantation because they can infect human cells in vitro and have the potential for transmission of unexpected pathogens to humans. In this research, 101 pigs, including four commercial breeds (23 Berkshire, 13 Duroc, 22 Landrace and 14 Yorkshire pigs), one native breed (19 Korean native pigs) and one miniature breed (10 NIH miniature pigs) were used to investigate insertional variations for 11 PERV loci (three PERV-A, six PERV-B and two PERV-C). Over 60% of the pigs harbored one PERV-A (907F8) integration and five PERV-B (B3-3G, B3-7G, 742H1, 1155D9 and 465D1) integrations. However, two PERV-A loci (A1-6C and 1347C1) and one PERV-B locus (B3-7F) were absent in Duroc pigs. Moreover, two PERV-C loci (C2-6C and C4-2G) only existed in Korean native pigs and NIH miniature pigs. The results suggest that PERV insertional variations differ among pig breeds as well as among individuals within a breed. Also, the results presented here can be used for the selection of animals that do not have specific PERV integration for xenotransplantation research.

The Use of Collagen Content as Determined by Spectral Domain Polarization-Sensitive Optical Coherence Tomography to Assess Colon Anastomosis Healing in a Rat Model

Son, K.H.,Jeong, H.-W.,Jung, W.-W.,Kim, H.-S.,Lee, S.K.,Kim, K.T.,Ahn, C.B.,Park, K.Y.,Kim, B.-M.,Lee, S.H. S. Karger AG 2014 European surgical research Vol.52 No.1

<P>Abstract</P><P><B><I>Background/Purpose:</I></B> Many studies have been undertaken to prevent anastomosis leakage of the colon, and several methods have been used to assess anastomosis healing, such as measurement of bursting pressure or hydroxyproline (a marker of collagen) content at the anastomosis site. However, these methods are inappropriate for comparing anastomosis healing at two time points in the same animals. In the present study, we measured the collagen level by spectral domain polarization-sensitive optical coherence tomography (SD-PS-OCT) to assess anastomosis healing. <B><I>Methods:</I></B> Sprague-Dawley rats were divided into groups C (saline-administered controls; study group) and M [a 5-fluorouracil (5-FU)-administered experimental group]. Immediately after end-to-end anastomosis of the colon, SD-PS-OCT images of anastomoses were taken (baseline). Animals were administered saline or 5-FU for 7 days. On the 7th postoperative day, SD-PS-OCT images were acquired, a histopathologic exam was performed, and hydroxyproline levels as well as mRNA expressions of collagen-1 and collagen-3 were measured at the anastomosis site. <B><I>Results:</I></B> Fibroblast proliferation and inflammatory cell infiltration were greater in group C than in group M. The mRNA expressions of collagen-1 and collagen-3 were substantially higher in group C. Hydroxyproline levels were higher in group M than in group C. Though collagen levels measured by SD-PS-OCT at 7 days were elevated compared with baseline in group C, no such changes were observed for group M. <B><I>Conclusion:</I></B> Collagen levels at the colon anastomosis site, measured with SD-PS-OCT, were not increased at 7 days postoperatively versus baseline when 5-FU was injected, but were increased in saline-treated controls. The measurement of collagen content by SD-PS-OCT was found to provide a good means of assessing anastomosis healing, because it allows in situ assessment of collagen contents at baseline and during the postoperative period.</P><P>© 2014 S. Karger AG, Basel</P>

비주얼 C++을 이용한 재료역학 해석 프로그램 개발

이상순(S.S. Lee),서성삼(S.S. Seo),이승철(S.C. Lee),허윤(Y. Hur),정해영(H.Y. Jung) 대한기계학회 2001 대한기계학회 춘추학술대회 Vol.2001 No.3

The computer program as a supplemental tool for a mechanics of materials course has been developed using visual C++. A unique feature of this computer program is that it is suitable for engineering students at the sophomore/junior level and for students who are totally new to the computer programing. Solutions to problems are given in both graphical and numerical forms. This program provides a learning environment where students can focus on understanding and solving various problems rather than typing cumbersome expressions and checking numerical errors.

Studies on the Detection of mecA Gene and Distribution of Enterotoxin Genes in Pathogenic Staphylococci Isolated from Korea Using Molecular Biologic Technique

Whang, S. C.,Lee, D. H.,Ryu, J. R.,Jung, S. K. 高麗大學校 倂設 保健大學 保健科學硏究所 1997 保建科學硏究論集 Vol.6 No.1

본 연구에서는 입상 검체에서 발견되는 병원성 포도상구균(S. aureus)과 methicillin 내성 포도상구균(MRSA)에서 각각 nurc과 mecA 유전자, 장독소인 enterotoxin A에서 enterotoxin E를 encoding하는 유전자들과 toxic shock syndrome toxin(tst) 유전자를 빠르개 탐지하고 독소형의 국내·외의 역학적인 분포를 조사하기 위하여 multiplex PCR을 수행하였다. 210개의 MRSA에서 두 개의 균주가 mecA 유전자 음성을 보인 것을 제외하고 모두 nuc유전자와 mecA유전자 양성을 나타냈다. 이 중 10개(80.5%)가 한 게 흑은 그 이상의 장독소에 대한 유전자를 지니고 있었으며 다른 41개 균주(19.5%)는 장독소 유전자에 대해 양성을 나타내지 않았다. 장독소A 유전자(sea)는 분리균 중 50.5%(n=105)에서 유전자가 중폭되었고 seb는 14.료쏭(n=30), sec는 23.3% (n=49), sed는 10.0%(n=21) 그리고 tst는 12.4%(n=26)가 증폭되었다. 58개의 균주들(27.68)은 두 개 이상의 장내독소 유전자가 증폭되었다. 가장 많이 나타난 독소 조합군은 sea와 seb로 26개 균주(12.4%)에서 발견되었으며 다음으로 빈번한 조합은 sec와 tst로 14균주(6.7%)로 나타났다. 210개 중 109개의 균주는 서울 지역에서 분리된 것이었고 101개는 부산 지역에서 분리된 균이었다. 부산지역에서 장내독소 A 유전자(sea)의 발생율은 서울에서보다 두 배 더 높게 나타났다(57.1% 대 23.6%). 그러나 장내독소 c유전자(sec)와 d유전자(sed)는 서울 지역에서 각각 23.6%와 17.9%로 비슷하게 나타난 반면에 부산 지역에서는 각각 2.0% 미만으로 거의 무시할 수 있을 정도로 낮게 나타났다. 한국의 장독소 형별 검출을 외국과 비교하면 장독소A의 검출빈도가 가장 높은 것은 같으나 차순으로 빈도가 높은 것이 외국의 경우 b유전자인데 반하여 한국에서는 c유전자로 실험결과 나타났다. 또한 한국에서의 d유전자 검출빈도가 b유전자 보다 높아 주된 유행형인 a유전자를 제외한 기타 독소형의 분포는 국가간 또는 지역간에도 차가 있는 것으로 결론지을 수 있다. In this study we attempted multiplex PCR for rapid detection of genes for nuc, mecA. enterotoxin A to E and TSST-l(tst) in bacterial lysates extracted from human strains of S aureus. In 210 isolates of methicillin-resistant Staphylococcus aureus (MRSA), all strains showed both nuc gene and mecA gene positive except two strains that showed only nuc gene positive. One hundred sixty nine(80.5%) of 210 MRSA isolates tested produced one or more toxins. Other 41(19.5%) isolates did not produce any of the toxins. Enterotoxin A gene(sea) was amplified in 50.5%(n=105) of the isolates, enterotoxin B(seb) in 14.3%(n=30), enterotoxin C(sec) in 23.3%(n=49), enterotoxin D(sed) in 10.0%(n=21) and TSST-l(tst) in 12.4%(n=26). Fifty eight strains(27.6%) amplified more than two enteroxin genes. The most common combination of toxin gene was sea and seb, which was found in 26(12.4%) strains, and the next frequent combination was sec and tst in 14(6.7%) strains from 210 isolates among which 109 MRSA strains tested were isolated in Seoul area and 101 in Pusan area. The frequency rate of enterotoxin A in Pusan was twice higher than that of Seoul with 57.1% to 23.6%. But the frequency rates of enterotoxins C and D genes in Seoul area are analogous with relatively narrow margin while those rates in Pusan area were almost negligible with less than 2% each. Apparent difference of enterotoxin type distribution was also found between the countries. Beside enterotoxin A which was most predominantely found in both European countries and Korea, enterotoxin C was the subsequently prevalent type of toxin in Korea instead of enterotoxin b which was found as the second most prevalent enterotoxin in some European countries

한우 c-fos 유전자의 염기서열 및 발현분석

유성란,정행진,정기철,이준헌,조규완,최재관,나기준,상병찬 한국동물자원과학회 2003 한국축산학회지 Vol.45 No.6

Cellular FOS(c-fos) protein is a transcription factor that forms heterodimers mostly with c-jun family and stimulates the transcription of genes containing AP-1 regulatory elements. This c-fos expression can control growth and differentiation of various precursor cells including myoblasts. The controls by c-fos gene have been identified for affecting skeletal muscle fiber traits which are the key determinants of meat quality in pigs. As a first step for identifying the relationship between c-fos gene and meat quality traits in cattle, we fully sequenced 1,443 bp of Hanwoo c-fos mRNA and analyzed expression patterns from various organs and muscle tissues. The sequence identities of Hanwoo c-fos with that of human, pig and mouse showed 89.8%, 93.3% and rib muscle from 7 organs and 9 different parts of muscles investigated. These results presented here can be used as a valuable marker for meat quality related traits in cattle with further verification.

혈청 Creatine Kinase측정 표준화에 관한 연구(Ⅵ)

이창규,이승관,조경진,정수경,박종성,박상숙,류정록,남현철,김상섭,김석수,장철수,최명재 高麗大學校 倂設 保健大學 保健科學硏究所 1998 保健科學論集 Vol.24 No.1

In European countries or Japan they made an attempt for the standardization of assays in AST, ALT, ALP, CK, LD and GGT 10 years ago. For the actualization of the trial, they managed to succeeded in development of certified reference material and enzyme reference material. And they are now forecasting the unification of test results produced differently under the respective situatons. Then, through the highly developed communication system, someone can access any test results whenever or whereever only if they want to. It means that we can expect much greater improvements in medical services through the information exchanges. In this study the authors tried to ascertain the interchangeability comparing the obtained results of the CK tests between two general hospitals. Fortunately, the data got in the internal QC programs came to fall within the normal tolerances. The reference intervals for the CK test were different accarding to the chosen reagents and the results from the pooled serum were also shown differently each other. However, from the two hospitals, we could get glucose K factors, upon which the measurements were obtained and compared. Using K factors we measured the CKs, then we multiply the CK values by correction coefficients. We could found that the two results were showing good coincidence in the comparison. The main purpose of the standardization of enzyme assays is the creation of a new unified value which can be expressed differently otherwise. Using the standardized values we can exploit the data everywhere, reduce the medical costs from repeated or duplicated tests, save the foreign exchanges preventing the diversification of impart connections.

Arbitrarily Primed PCR을 이용한 한국에서 유행하는 황색포도상구균의 분자유전형에 대한 연구

황선철,이창규,이승관,이동호,정수경,최현일,윤건석,정운원,윤효숙 高麗大學校 倂設 保健大學 保健科學硏究所 1998 保健科學論集 Vol.24 No.1

Eighty methicillin-resistant Staphylococcus aureus(MRSA) isolates were typed by applying arbitrarily primed-PCR(AP-PCR) method to clarify their distribution of molecular genetical characteristics. Among 40 gentamicin resistant strains of MRSA(GR-MRSA), 33 isolates drawn on the dendrogram fell into a single cluster at the similarity level of 90% when primer S₁ was used. However, with the primer S₂, 24 out of 40 strains fell into a single cluster at the similiarity 90%. In the meantime, 22 out of 40 strains amplified fell into a single cluster at the similarity of 90% when the primer E₂ was used. From the combined data obtained, it can be statistically said that 65.8% of GR-MRSA isolates are related with genetical characteristics. In 40 gentamycin susceptible MRSA(GS-MRSA) strains, 18, 19 and 13 strains drawn on the dendrogram fell into a single cluster at a similiarity level of 90% with the primers S₁, S₂ and E₂, respectively. From the combined data obtained by the three above AP-PCR profiles, it can be concluded that 41.7% of GS-MRSA isolates showed high relatedness genetically.