하천 만곡률과 홍수량에 따른 수면경사도 산정

최한규,이문희,백효선 강원대학교 산업기술연구소 2006 産業技術硏究 Vol.26 No.B

In this research, we made a one and two-dimensional analysis of numerical data collected from the bend curvature of a bended river section. According to the result from the numerical analysis, the inflow & output angle caused a water level deviation which increased with an increase of the flood discharge. From the water level deviation of our two-dimensional numerical model, we obtained the maximum slope of 6.67% when the inflow and output angle was 105 degrees and the flood discharge was 500 CMS. As for the right side, the differences with the one-dimensional numerical model were reduced when the angle was more than 90˚. As for the left side the differences were reduced when the angle was more than 105˚. For a river with more than 90 degrees bend curvature, a hydraulic experiment would be more appropriate than a numerical analysis.

하천 만곡률과 홍수량에 따른 수면경사도 산정

최한규,이문희,백효선 강원대학교 산업기술연구소 2006 産業技術硏究 Vol.26 No.A

In this research, we made a one and two-dimensional analysis of numerical data collected from the bend curvature of a bended river section. According to the result from the numerical analysis, the inflow & output angle caused a water level deviation which increased with an increase of the flood discharge. From the water level deviation of our two- dimensional numerical model, we obtained the maximum slope of 6,67% when the inflow and output angle was 105 degrees and the flood discharge was 500 CMS. As for the right side, the differences with the one-dimensional numerical model were reduced when the angle was more than 90˚. As for the left side the differences were reduced when the angle was more than 105˚. For a river with more than 90 degrees bend curvature, a hydraulic experiment would be more appropriate than a numerical analysis.

구강악안면영역의 3차원 CT 영상 재형성시 역치 및 불투명도에 대한 연구

최문경,이삼선,허경회,이원진,최순철 대한구강악안면방사선학회 2009 Imaging Science in Dentistry Vol.39 No.1

Purpose : This study was designed to determine a proper threshold value and opacity in three-dimensional CT volume rendering of oral and maxillofacial area. Materials and Methods : Three-dimensional CT data obtained from 50 persons who were done orthognatic surgery in department of oral and maxillofacial radiology of Seoul National University retrospectively. 12 volume rendering post-processing protocols of combination of threshold (100HU, 150HU, 221HU, 270HU) and opacity (58%, 80%, 90%) were applied. Five observers independently evaluated image quality using a five-point range scale. The results were analyzed by receiver operating characteristic curves, ANOVA and Kappa value. And three oromaxillofacial surgeons chose the all images that they thought proper clinically in the all of images. Results : Analysis using ROC curves revealed the area under each curve which indicated a diagnostic accuracy. The highest diagnostic accuracy appear with 100HU and 58% opacity. and the lowest diagnostic accuracy appear with 221HU and 58% opacity that are being used protocol in department of oral and maxillofacial radiology of Seoul National University. But, no statistically significant difference was noted between any of the protocols. And the number of proper images clinically that chosen by three oromaxillofacial surgeons is the largest in the cases of protocol 8 (221HU, opacity 80%) and protocol 11 (270HU, opacity 80%) in one after the other. Conclusion : Threshold and opacity in volume rendering can be controled easily and these can be causes of making an diagnostic accuracy. So we need to select proper values of these factors.

하악과두에 발생한 호산구육아종

최문경,허경회,이원진,오성욱,이삼선 대한구강악안면방사선학회 2008 Imaging Science in Dentistry Vol.38 No.1

The present study reports a case of eosinophilic granuloma of the mandibular condyle. Eosinophilic granulomas on the mandibular condyle are very rare, but there are several common clinical and radiographic presentations. The clinical presentations involve swelling on preauricular area, limitation of opening, TMJ pain, etc. The radiographic presentations involve radiolucent lytic condylar lesion with or without pathologic fracture. Sometimes new bone formations are observed. The purpose of the article is to add new cases to the literatures.

물림변형과 간섭을 고려한 평치차의 치형수정

심문보,최연선 成均館大學校 科學技術硏究所 1999 論文集 Vol.50 No.1

Gear plays an important role for the power transmission of a machine. The rotation of driven gear should be that of the driving gear with the proportion of the gear ratio. However, the deviations between them are resulted from the deflections due to transmission error, which leads to vibrations and noise during gear meshing. Transmission error is defined as the difference of the rotation between driving and driven gear due to teeth deformation, which also causes an interference during meshing. The interference is one of severe causes of the vibration and noise of gear driving system. In this study, a tooth flank modification is suggested for the prevention of the interference by numerical simulation of gear meshing. The compliance of gear tooth and transmission error are calculated for the tooth modification. The interference due to transmission error is predicted numerically and the quantity of tooth flank modification is calculated to remove the interference.

인도네시아 지진해일에 대한 의료지원보고

조수형,김선표,최웅지,김성중,조남수,이준영,문성표 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

An unprecedented magnitude of disaster, Tsunami, washed away Southeast Asia, on December 26, 2004. and more than 200,000 peoples were killed by the disaster. Staffs of our hospital visited Indonesia for voluntary medical supports from January 12, to January 21, 2005. We summarize here our 10 days' experiences in Indonesia.

개질 아스팔트 혼합물의 변형강도 측정 연구

김광우,도영수,이기호,조문진,최선주 강원대학교 부설 석재복합신소재 제품연구센터 2004 석재연 논문집 Vol.9 No.-

본 논문은 아스팔트 혼합물의 소성변형 저항성과 상관성이 높은 특성치를 찾고자 Kim test를 개발하여 현재 적용성 연구결과를 다루고 있다. 이 논문은 새로운 강도특성치인 변형강도(S_(D))를 개발하는 Kim, test 연구의 4단계 연구 결과이다. 13 mm 골재(편마암, 화강암)와 입도(밀입도, 갭입도) 5가지 폴리머로 제조한 8가지 바인더로 두 가지 입도에서 소성변형 저항성이 다른 32가지 혼합물을 만들었다. 슬래브(305㎜×305㎜×62㎜)공시체를 제조하여 한쪽은 Kim, test를 수행하기 위하여 18 cm정도로 잘라서 코어를 3개 채취하고 다른 한쪽은 12cm크기로 하여 반복주행시험을 실시하였다. Kim, test는 하중봉 3(0.75), 4(1.0)을 사용하였다. W/T시험으로부터 최종 침하 깊이와 동적안정도의 두 가지 소성변형 계수를 각 혼합물별로 구했다. 각 하중봉과 골재별, 입도별로 S_(D)와 소성변형 계수간의 통계적 상관관계 분석을 수행한 결과 S_(D)와 소성변형 계수와의 결정계수가 매우 높게 (R²>0.95) 나타났다. 하중봉 4(1.0)이 3(0.75)보다 다소 높은 상관성을 보였다. 향후 Kim test실험에서 하중봉 4(1.0)을 사용하고 4단계 방법을 이용한다면 소성변형 특성치인 침하깊이(DR)와 동적안정도(DS)와의 상관성이 매우 큰 시험법이 될 것이다. 또한 변형강도의 파괴 메커니즘은 콘크리트의 펀칭파괴와 유사하여 콘크리트의 전단강도 추정식을 근거로 아스팔트 콘크리트의 재료 특성에 적합한 추정식 계수 ◁ 원문 수식 참조 ▷ 를 얻었다. 이 식을 이용한다면 아스팔트 콘크리트가 견딜 수 있는 임계하중을 변형강도에 근거하여 추정할 수 있을 것이다. This study shows predictability of rut parameters of modified and unmodified asphalt concretes based on the deformation strength (S_(D)) which is calculated from the maximum load, deformation and size variables of loading head under simple static loading. This paper is the result of latest studies, phase 4 which is a part of Kim, Test studies for developing a new strength property for asphalt concrete. Two aggregates, gneiss and granite, two gradations, dense-graded, gap-graded, with maximum, size of 13mm and eight binders using different contents of five polymers (RLDPE, RHDPE, LDPE, SBS, SBR) were used to produce 32 different mixtures. A slab (305㎜×305㎜×62㎜) was cut into two pieces(18cm and 12cm width) and three 10cm cores were taken for S_(D) test from the larger piece and wheel tracking test was performed on the smaller piece. Kim test was performed using loading head 4(1.0), 3(0.75). Two rut parameters, depth of rut and dynamic stability, from the rut depth-cycle curve from a WT test were obtained for each mixture. Statistical analysis were performed for each loading head, aggregate, and gradation to find out correlation between S_(D) values and each rut parameter. The analysis results showed that S_(D) had high R² (over 0.95) on the average with rut parameters. The loading head 4(1.0) showed R² better than 3(0.75). It is concluded that S_(D) is the property that has excellent predictability for rut parameter of asphalt concretes. An equation, ◁ 원문 수식 참조 ▷ was obtained based on the equation of concrete shear load creating punching failure and current test data, because the failure mechanism of S_(D) is similar to punching failure of concrete. In the equation, P is shearing force creating punching effect, b is length of perimeter of punching area and d is depth of specimen. If this formula is used, a critical load for deformation failure will be predicted based on the S_(D).

Helicobacter pylori-derived outer membrane vesicles stimulate interleukin 8 secretion through nuclear factor kappa B activation

( Mun Sun Choi ),( Eun Young Ze ),( Jae Yong Park ),( Tae-seop Shin ),( Jae Gyu Kim ) 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.4

Background/Aims: Bacteria-derived outer membrane vesicles (OMVs) are commonly associated with various biological activities and functions. Helicobacter pylori-derived OMVs are thought to contribute to pathogenesis. This study aimed to investigate the effects of H. pylori-derived OMVs. Methods: H. pylori strains were isolated from patients with gastritis, gastric ulcer, or gastric cancer using endoscopic biopsy. The U-937, AGS, and MKN-45 cell lines were exposed to H. pylori and H. pylori-derived OMVs. The expression of interleukin 8 (IL-8) messenger RNA (mRNA) was assessed using reverse transcription-polymerase chain reaction (RT-PCR) and real-time RT-PCR, and IL-8 secretion was analyzed using enzyme-linked immunosorbent assay. Nuclear factor kappa B (NF-κB) activation was evaluated by Western blotting. Results: H. pylori and H. pylori-derived OMVs induced the expression of IL-8 mRNA and protein. Importantly, the bacteria induced higher IL-8 mRNA and protein expression than the OMVs. IL-8 expression was induced to different levels in response to H. pylori-derived OMVs from hosts with different gastric diseases. Western blotting revealed the increased phosphorylation and reduced degradation of inhibitor of NF-κB alpha in cells exposed to OMVs. Conclusions: H. pylori-derived OMVs may aid the development of various gastric diseases by inducing IL-8 production and NF-κB activation.

Expression of vascular endothelial growth factor receptor-3 mRNA in the rat developing forebrain and retina

Choi, Jeong-Sun,Shin, Yoo-Jin,Lee, Ji-Yeon,Yun, Hou,Cha, Jung-Ho,Choi, Jae-Youn,Chun, Myung-Hoon,Lee, Mun-Yong Wiley Subscription Services, Inc., A Wiley Company 2010 Journal of comparative neurology Vol.518 No.7

<P>Vascular endothelial growth factor receptor (VEGFR)-3, a receptor for VEGF-C and VEGF-D, is expressed in neural progenitor cells, but there has been no comprehensive study of its distribution in the developing brain. Here, the temporal and cell-specific expression of VEGFR-3 mRNA was studied in the developing rat forebrain and eye. Expression appeared along the ventricular and subventricular zones of the lateral and third ventricles showing ongoing neurogenesis as early as embryonic day 13 but was progressively down-regulated during development and remained in the subventricular zone and rostral migratory stream of the adult forebrain. VEGFR-3 expression was also detectable in some differentiating and postmitotic neurons in the developing cerebral cortex, including Cajal-Retzius cells, cortical plate neurons, and subplate neurons. Expression in the subplate increased significantly during the early postnatal period but was absent by postnatal day 14. It was also highly expressed in nonneural tissues of the eye during development, including the retinal pigment epithelium, the retinal ciliary margin, and the lens, but persisted in a subset of cells in the pigmented ciliary epithelium of the adult eye. In contrast, there was weak or undetectable expression in the early neural retina, but a subset of retinal neurons in the postnatal and mature retina showed intense signals. These unique spatiotemporal mRNA expression patterns suggest that VEGFR-3 might mediate the regulation of both neurogenesis and adult neuronal function in the rat forebrain and eye. J. Comp. Neurol. 518:1064–1081, 2010. © 2009 Wiley-Liss, Inc.</P>

Enhanced Expression of SOCS-2 in the Rat Hippocampus after Transient Forebrain Ischemia

Choi, Jeong-Sun,Shin, Yoo-Jin,Lee, Ji-Yeon,Choi, Jae-Youn,Cha, Jung-Ho,Chun, Myung-Hoon,Lee, Mun-Yong Mary Ann Liebert 2009 JOURNAL OF NEUROTRAUMA - Vol.26 No.11