제초제 Paraquat의 독성에 미치는 용존 산소의 영향

윤현숙,이묘일,이혜정 효성여자대학교 가정대학 학도호국단 1985 家政大論集 Vol.4 No.-

제초제 paraquat는 S. cerevisiae에 독성을 나타내었으며 독성의 크기는 산소공급 상태에 크게 의존하였다. 즉 균체를 진탕하면서 0.3M paraquat로 4시간 처리한 결과 생존률이 33.4%에 불과하였으나 정치배양으로 처리한 경우에는 85.2%가 생존하였다. 균주의 진탕, 정치배양의 배양법 차이에 따른 생존률의 차이는 5% 미만으로서 산소공급이 원활한 상태에서 paraquat의 독성이 더욱 증가되었다. To understand the effect of oxygen on toxicity of a herbicide paraquat, exponeotiallygrowing cells of the Sacckaromyces cerevisiae were exposured to 10^-3M paraquat. It wascontinued for four hours at 30℃ with or without agitation for air supply. The cells revealed a 33.4% of survival when they were expousured to the herbicidewith vigorous shaking. However, they showed a 85.2% of survival when they exposuredwithout shaking. The content of oxygen soluble in the cultural medium was remarkablydecreased from 38ppm to 8ppm during for four hours of cultivation of the cells withshaking and without exposure to the herbicide. On contrastly to it, little change inoxygen content was found by the herbicide treatment. It was clear from the results that toxicity of the paraquat was enhenced byconcomitant presence of oxygen.

순차 컴비네이터를 기반으로 하는 병렬 그래프 리덕션

徐正勳,鄭盛允,尹英雨 嶺南大學校 工業技術硏究所 1992 연구보고 Vol.20 No.1

This study discusses the graph reducer to improve the execution speed of functional languages. We develop the G-machine compiler which translates serial combinator to a sequence of instructions. The SubMiranda, which is a subset of the Miranda, is chosen as a test language. The implemented G-machine compiler translates serial combinator to an intermediate code, G-code, and then does macro-expansion to create a target code, C-code.

과도 절삭에서의 절삭 공정 시뮬레이션

고정훈,조동우,윤원수,김주한 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

In most of the existing mechanistic models, the cutting process simulation is often restricted to a single path machining operation under a fixed cutting condition. Complex cutting processes such as die or mold manufacturing, however, are performed under two- or three-dimensional multiple tool paths. Since the tool paths in CNC machining are composed of line and arc segments, transient cuts are frequently occured due to the multiple paths. Even in steady cuts, the width of cut is varied with each segment. In this regard, this paper deals with the development of process simulation system for transient cuts, where continuously changing cutting configuration is computed, and then the cutting forces are predicted.

열화조건하의 시멘트 혼입 폴리머계 방수재의 내피로성

송훈,도정윤,소양섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

Polymer-modified paste-applied membrane waterproofing materials has been used as waterproofing materials, e.g. for basement and water tank due to both simple handling and excellent workability. However, as for the polymer-modified paste-applied membrane waterproofing materials, the durability is easy to be degraded by the occurrence and propagation of crack. An aim of this study is to make clear performance of the polymer-modified paste-applied membrane waterproofing materials of which performances are improved through this study. PAE and EVA show the result to be markedly dependent on the condition and period of deterioration. Presence of reinforcement causes the influence to the physical properties of waterproofing materials. In addition, a reinforcement effect of non-woven fabric on cracking can be expected.

정신분열증 환자와 우울증 환자의 MMPI-2 프로파일

고윤화,손용훈,윤정흠,오상우,이귀행,박민철 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

Background: Minnesota multiphasic personality inventory-2(MMPI-2) is superior to its predecessor in differential diagnosis. this study was to investigate MMPI-2 profiles of the patients with schizophrenia and depression and to discriminate among two groups. Methods: The sample consisted of 35 patients with schizophrenia(male 24, female 11), 35 patients with depression(male 18, female 17) diagnosed by the diagnostic and statistical manual of mental disorders(DSM-IV) for schizophrenia & depression at department of neuropsychiatry in WonKwang University from January 2005 to December 2007. The data from the results were analyzed statistically by t-test and discriminant analysis. Results: The results were as follows. First, according to t-test results the comparison of schizophrenia patients and depression patients in MMPI-2 among two groups showed significant differences; the validity scales: F, F(P); The clinical scales: D, Pa; The restructured clinical scales: Rcd(dem), RC4, RC6, RC8; The content scales: ANX, DEP, BIZ; The supplementary scales: AGGR, PSYC, Mt, GF, O-H. Second, as a results discriminant analysis, BIZ, D were significant predictors in distinguishing patients with schizophrenia from patients with depression. Third, probability to be discriminated schizophrenia in schizophrenia was 91.4%, probability to be discriminated depression in depression was 85.7%. Conclusion: Finally, we remind readers that although the MMPI-2 may prove to be useful in the task of differential diagnosis, it should be used only in combination with other patient information. 배경: MMPI-2는 감별진단에서 기존의 MMPI 보다 더 우수하다. 본 연구는 정신분열증 환자와 우울증 환자의 MMPI-2 프로파일과 두 집단을 판별하는 연구를 하였다. 방법: 2005년 1월부터 2007년 12월까지 원광대학교 병원 신경정신과에서 정신분열증과 우울증으로 진단된 정신분열증 환자 35명(남성 24명, 여성 11명), 우울증 환자 35명(남성 18명, 여성 17명)이 본 연구에 참여하였다. 자료는 t-검증과 판별분석으로 분석하였다. 결과: 결과는 다음과 같다. 1. t-검증 결과, 두 집단간 유의미한 차이를 보인 척도들로는 타당도 척도에서 F, F(P) 척도, 임상척도에서 D, Pa, 척도, 재구성 임상척도에서 Rcd(dem), RC4, RC6, RC8척도 였다. 내용척도에서는 ANX, DEP, BIZ척도 였으며 보충척도에서는 AGGR, PSYC, MT, GF O-H척도 였다. 2. 판별 분석 결과로서, 정신분열증과 우울증을 구별하는데 가장 유의한 예언요소는 BIZ, D척도로 나타났다. 3. 판별함수를 통한 진단율은 정신분열증을 정신분열증으로 판별해주는 정확도는 91.4%였고, 우울증을 우울증으로 판별해주는 정확도는 85.7%였다. 결론: 본 연구 결과를 통해서 MMPI-2가 두 집단을 감별하는데 유용하다고 증명되었을지 모르지만 더욱 정확하게 감별하기 위해서 환자의 기타 정보를 사용해야 할 것이다.

혼합형 자가면역성용혈성빈혈과 동반된 Evans 증후군 1례

선길홍,윤찬영,박상곤,박경희,우정주,한경택,김진화,김영훈,정춘해,박치영 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Evans syndrome is defined as a simultaneous or sequential occurrence of autoimmune hemolytic anemia and autoimmune thrombocytopenia. Autoimmune hemolytic anemia (AIHA) is usually induced by IgG warm autoantibody or cold-active IgM antibodies reacting specifically with antigens associated with a patient's RBC. AIHA is a fairly uncommon disorder, with estimates of the incidence at 1 to 3 cases per 100,000 per year. Mixed-type AIHA is a relatively uncommon form of AIHA, with studies noting the incidence of 7-8% among cases of AIHA. We experienced a patient, 46-year-old woman who was diagnosed having a very rare clinical presentation of mixed warm and cold antibody mediated Evans syndrome. She was treated with corticosteroid therapy only and has been maintaining a complete response for 15 weeks. 저자들은 혼합형의 자가면역성 용혈성 빈혈과 자가면역성 혈소판 감소증이 동시에 발생한 혼합형 Evans 증후군으로 진단하고 스테로이드 요법 후 혈액학적으로 회복된 상태로 15주가 지난 현재 steroid 5 mg/일 까지 감량한 상태에서 추적 관찰 치료중인 46세 여자 환자를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

화재시 제연 및 피난을 위한 기능성 차압 조절장치 개발에 관한 연구

정기창,김정훈,이정윤 한국안전학회 2004 한국안전학회지 Vol.19 No.1

The smoke and toxic gases generated fi-om the building fires are proved to cause human death. Therefore, the necessity and significance of smoke control have been emphasized, and lots of studies for developing improved smoke management system have been carried out. In this study, the experiments were conducted to evaluate a function and performance in newly developed smoke management system using mechanical pressurization. As a result of this experiment, the differential pressure was 4OPa--60Pa and the air velocity through the door was 0.7m/s between safety zone and fire zone. The functional pressure control equipment which could make proper pressure and maintain differential pressure between safety zone and fire zone was developed And it will give a lot of helps to evacuation activity for peoples in building and fire fighting.

공사중 도로점용에 따른 교통특성에 관한 연구

김갑수,도윤정,전종훈 영남대학교 지역발전연구소 2003 영남지역발전연구 Vol.32 No.-

도로운영과 관리의 효율성 측면에서 볼 때, 도로를 점용하여 공사를 시행하는 것은 차량의 소동 뿐만 아니라 안전문제와 밀접하게 관련되어 있다. 따라서, 도로점용공사구간의 부적절한 관리는 안전이나 운영의 악화를 초래하는 주된 원인이 될 수 있다. 최근 도로의 유지관리 개념의 중요성이 대두되어 도로의 유지보수 관련작업이 잦아지고, 도로 외적인 공공시설의 설치 작업이 빈번하게 발생하고 있어, 도로를 점유하는 경우는 앞으로도 증가할 것으로 예상되므로 이에 대해 체게적이고 합리적인 해결방안이 강구되어야 한다. 본 연구에서는 공사 중 도로를 점유하는 유형을 분류하고 공사구간의 교통특성을 중심으로 도로점유유형에 따른 지체도를 분석하여 교통지체를 최소화할 수 있는 방안을 제시하기 위한 기초자료로 활용하는 것을 목적으로 한다.

백서에서 Depulpin®과 Formocresol에 대한 치수와 치근단 조직의 반응

문형인,김선호,황윤찬,오병주,황인남,김선헌,정선와,윤창,오원만 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.4

One fifth dilution of formocresol is usually for pulpotomy of the primary teeth and emergency pulpotomy of the permanent teeth. However, the use of formaldehyde has been subjected to criticism because it may be absorbed into the blood stream and become distributed systemically, it may also alter the pulp tissue rendering it immumologically active, and have carcinogenic potential. Recently Depulpin®(VoCo., Germany) gains popularity as a devitalizing agent during root canal therapy in spite of high concentration of 49% paraformaldehyde because it facilitate devitalization of pulp and make root canal therapy easier. But there have been not enough publications about the reaction of pulp and periapical tissue caused by Depulpin. This study was performed to evaluate the histological changes in pulp and periapical tissue of rats after pulpotomy using formocresol and Depulpin and to elucidate the toxic effects of these agents. Thirty six Sprague-Dawley rats were anesthetized by intraperitoneal injection of ketamine. Maxillary first molar teeth were used for pulpotomy with formocresol and Depulpin. Rats were sacrificed after 2 days, 4 days, 1 week, 2 weeks, 3 weeks and 4 weeks respectively. Specimens were histologically observed by light microscope changes in pulp and periapical tissue. The obtained results were as follows. 1. Formocresol group A zone of fixed tissue, in which odontoblasts could clearly be defined, was present directly underneath the pulpotomy dressing in almost all teeth of this group. This was followed by an area of necrotic tissue which resembled dried out fibrous tissue with no cellular detail except some pyknotic nuclei. In the specimens of after 2 days, 4 days, 1 week, 2 weeks in which vital tissue was present. it was separated from the fibrous area by a zone of inflammation. In the specimens of after 3 weeks and after 4 weeks, inflammatory infiltrate was in the periodontal ligament adjacent to the apical foramina of the teeth. 2. Depulpin® group The area of necrotic tissue which had no cells and fibers , was present adjacent to the dressing. This was followed by dried out fibrous tissue with no cellular details except some pyknotic nucleli. A short stump of vital pulp with odontoblasts was present at the end of the canal after 2 days. Inflammatory infiltrate was in the periodontal ligament after 4 days and after 1week. Severe root resorption and necrosis of periapical tissue opposite the root resorption site were defined after 2 weeks and after 3 weeks. Periapical lesion which consist of necrotic tissue surrounded by a fibrous connective wall. was found after 4 weeks. The results indicated that Depulpin can cause more adverse reaction to the dental pulp and periapical tissue than formocresol, and further studies are needed for its clinical use with safety.

Neuroprotective Effect of Coreopsis laceolata Extract Against Oxidative Stress Induced Apoptosis in PC12 Cells

Yun Jeong Ji(지윤정),Ji Yeon Lee(이지연),Jeong Yong Park(박정용),Hyung Don Kim(김형돈),Dong Hwi Kim(김동휘),Seung Eun Lee(이승은),Gwi Young Jang(장귀영),Je Hun Choi(최재훈),Su Ji Choi(최수지),Kyung Hye Seo(서경혜) 한국약용작물학회 2019 한국약용작물학회 학술대회논문집 Vol.2019 No.1