An Optimized Computation Offloading and Resource Allocation Strategy in Mobile Edge Computing Using Deep Reinforcement Learning

Yu Qiao,Md. Shirajum Munir,Choong Seon Hong 한국정보과학회 2022 한국정보과학회 학술발표논문집 Vol.2022 No.06

Boosting Federated Learning Convergence with Prototype Regularization

Yu Qiao,Huy Q. Le,Choong Seon Hong 한국정보과학회 2023 한국정보과학회 학술발표논문집 Vol.2023 No.6

Comparing eight types of ginsenosides in ginseng of different plant ages and regions using RRLC-Q-TOF MS/MS

Yu-Lin Dai,Meng-Dan Qiao,Peng Yu,Fei Zheng,Hao Yue,Shu-Ying Liu 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.2

Background: This article aims to compare and analyze the contents of ginsenosides in ginseng ofdifferent plant ages from different localities in China. Methods: In this study, 77 fresh ginseng samples aged 2e4 years were collected from 13 differentcultivation regions in China. The content of eight ginsenosides (Rg3, Rc, Rg1, Rf, Rb2, Rb1, Re, and Rd) wasdetermined using rapid resolution liquid chromatography coupled with quadrupoleetime-of-flighttandem mass spectrometry (RRLC-Q-TOF MS/MS) to comparatively evaluate the influences of cultivationregion and age. Results: Ginsenoside contents differed significantly depending on age and cultivation region. The contentsof ginsenosides Re, Rc, Rg1, Rg3, and Rf increased with cultivation age, whereas that of ginsenoside Rb1peaked in the third year of cultivation. Moreover, the highest ginsenoside content was obtained fromChangbai (19.36 mg/g) whereas the lowest content was obtained from Jidong (12.05 mg/g). Ginseng fromJilin Province contained greater total ginsenosides and was richer in ginsenoside Re than ginseng of thesame age group in Heilongjiang and Liaoning provinces, where Rb1 and Rg1 contents were relatively high. Conclusion: In this study, RRLC-Q-TOF MS/MS was used to analyze ginsenoside contents in 77 ginsengsamples aged 2e4 years from different cultivation regions. These patterns of variation in ginsenosidecontent, which depend on harvesting location and age, could be useful for interested parties to chooseginseng products according to their needs.

Mesenchymal stem cell-derived exosome mir-342-3p inhibits metastasis and chemo-resistance of breast cancer through regulating ID4

Yu Shuyao,Zhou Yuhui,Niu Ligang,Qiao Yan,Yan Yu 한국유전학회 2022 Genes & Genomics Vol.44 No.5

Background: The mesenchymal stem cell-derived exosome (MSCs-exo) carrying microRNAs have been proved to regulate tumor biological activities. Clarifying molecular mechanism and identifying predictive microRNAs will be of great value in anti-tumor therapy improvement. Objective: We aimed to investigate the regulatory role of microRNA-342-3p (miR-342-3p) in MSCs-exo on breast cancer. Methods: Breast cancer tissues and cell lines were used to evaluate miR-342-3p expression in patients with or without lymph node/distal organ metastasis. The impact of MSCs-exo expression on tumor cell chemo-resistance and invasion/migration was measured. Dual-luciferase reporter gene assay was applied to identify binding site. Inhibitor of differentiation 4 (ID4) siRNA and miR-342-3p inhibitor transfection was conducted to further explore the miR-342-3p/ID4 axis on chemo-resistance and metastasis of breast cancer cells. Results: Breast cancer cells revealed significantly lower level of miR-342-3p in patients with metastatic diseases. miR-342-3p suppressed invasive and chemo-resistant behavior of breast cancer tumor cells. Binding site between miR-342-3p and ID4 was proved. ID4 could reverse the influence of miR-342-3p on chemo-resistance. The tumor inhibition effect of IDA siRNA in vivo was also identified. Conclusions: This study demonstrated that miR-342-3p acted as potential tumor suppressor by inhibiting metastasis and chemo-resistance of breast cancer cells through targeting ID4. This study might provide potential therapy targets for the treatment of breast cancer.

Analysis of Genetic Diversity of Japanese Plum Cultivars Based on RAPD, ISSR, and SSR Markers

Yu Shan Qiao,Jing Gui Fang,Yu Cong,Zhen Zhang 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

Surgical management of inflammatory bowel disease in China: a systematic review of two decades

( Qiao Yu ),( Ren Mao ),( Lei Lian ),( Siew Chien Ng ),( Shenghong Zhang ),( Zhihui Chen ),( Yanyan Zhang ),( Yun Qiu ),( Baili Chen ),( Yao He ),( Zhirong Zeng ),( Shomron Ben-horin ),( Xinming Song 대한장연구학회 2016 Intestinal Research Vol.14 No.4

Background/Aims: The past decades have seen increasing incidence and prevalence of inflammatory bowel disease (IBD) in China. This article aimed to summarize the current status and characteristics of surgical management for IBD in China. Methods: We searched PubMed, Embase, and Chinese databases from January 1, 1990 to July 1, 2014 for all relevant studies on the surgical treatment IBD in China. Eligible studies with sufficient defined variables were further reviewed for primary and secondary outcome measures. Results: A total of 74 studies comprising 2,007 subjects with Crohn`s disease (CD) and 1,085 subjects with ulcerative colitis (UC) were included. The percentage of CD patients misdiagnosed before surgery, including misdiagnosis as appendicitis or UC, was 50.8%±30.9% (578/1,268). The overall postoperative complication rate was 22.3%±13.0% (267/1,501). For studies of UC, the overall postoperative complication rate was 22.2%±27.9% (176/725). In large research centers (n>50 surgical cases), the rates of emergency operations for CD (P =0.032) and in-hospital mortalities resulting from both CD and UC were much lower than those in smaller research centers (n≤50 surgical cases) (P =0.026 and P <0.001, respectively). Regarding the changes in CD and UC surgery over time, postoperative complications (P =0.045 for CD; P =0.020 for UC) and postoperative in-hospital mortality (P =0.0002 for CD; P =0.0160 for UC) both significantly improved after the year 2010. Conclusions: The surgical management of IBD in China has improved over time. However, the rates of misdiagnosis and postoperative complications over the past two decades have remained high. Large research centers were found to have relatively better capacity for surgical management than the smaller ones. Higher quality prospective studies are needed in China. (Intest Res 2016;14:322-332)

Prototype Helps Federated Learning: Towards Faster Convergence

Yu Qiao,Seong-Bae Park,Sun Moo Kang,Choong Seon Hong 한국정보과학회 2022 한국정보과학회 학술발표논문집 Vol.2022 No.12

Comparing eight types of ginsenosides in ginseng of different plant ages and regions using RRLC-Q-TOF MS/MS

Dai, Yu-Lin,Qiao, Meng-Dan,Yu, Peng,Zheng, Fei,Yue, Hao,Liu, Shu-Ying The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.2

Background: This article aims to compare and analyze the contents of ginsenosides in ginseng of different plant ages from different localities in China. Methods: In this study, 77 fresh ginseng samples aged 2-4 years were collected from 13 different cultivation regions in China. The content of eight ginsenosides (Rg₃, Rc, Rg₁, Rf, Rb₂, Rb₁, Re, and Rd) was determined using rapid resolution liquid chromatography coupled with quadrupole-time-of-flight tandem mass spectrometry (RRLC-Q-TOF MS/MS) to comparatively evaluate the influences of cultivation region and age. Results: Ginsenoside contents differed significantly depending on age and cultivation region. The contents of ginsenosides Re, Rc, Rg₁, Rg₃, and Rf increased with cultivation age, whereas that of ginsenoside Rb₁ peaked in the third year of cultivation. Moreover, the highest ginsenoside content was obtained from Changbai (19.36 mg/g) whereas the lowest content was obtained from Jidong (12.05 mg/g). Ginseng from Jilin Province contained greater total ginsenosides and was richer in ginsenoside Re than ginseng of the same age group in Heilongjiang and Liaoning provinces, where Rb₁ and Rg₁ contents were relatively high. Conclusion: In this study, RRLC-Q-TOF MS/MS was used to analyze ginsenoside contents in 77 ginseng samples aged 2-4 years from different cultivation regions. These patterns of variation in ginsenoside content, which depend on harvesting location and age, could be useful for interested parties to choose ginseng products according to their needs.

중국 내 학원에서의 한국어 학습자의 학습 실태 분석

교우박 ( Yu Bo Qiao ) 고려대학교 한국어문교육연구소 2011 한국어문교육 Vol.9 No.-

1992년 중·한 수교 이후, 한국 드라마의 유입과 한류 열풍으로 중국 각지에서 한국어 학원이 우후죽순처럼 생겨났다. 한국어 학원 교육은 대학교의 한국어정규교육에 비해 그 수가 많고 분포지역이 넓으며 학습자가 다양하고 학습동기도 다양해, 전국의 한국어학원 학습자를 통합적으로 분석하기는 어렵다. 이 때문에. 본고에서는 중국 한 도시의 한국어학원 학습자를 대상으로 하여 무작위 설문조사를 했다. 설문내용은 크게 세 부분으로 나눌 수 있다. 첫 번째 부분은 학습자의 개인정보이다. 이 부분을 통해 학원에서 한국어를 학습하는 학습자의 성별, 나이, 직업 및 수업 이외의 한국어 학습시간 등 주요 특징을 살펴보고자 한다. 두 번째 부분은 학습동기 유형이다. Gardner & Lam bert는 사회언어학적인 시각에서 학습동기를 통합적인 동기(integrative movation)와 도구적인 동기(instrumental motivation)로 나누었다. 본고에서는 학습동기의 이런 분류를 근거로 하여 학원에서 한국어를 학습하는 학습자들의 학습동기를 살펴보고자 한다. 세 번째 부분은 학습 방식이다. 이 부분에서는 학원에서 한국어를 학습하는 학습자들이 선호하는 수업 외 시간의 학습방식을 생활적 방식과 학교적 방식 두 가지로 나누어 살펴보고자 한다. 이 연구의 결과가 중국 내의 한국어 학원에서 공부하는 한국어학습자들의 학습상황을 밝혀, 중국 내 한국어학원의 설립과 발전에 도움이 되기를 바란다. In 1992 China and South Korea established diplomatic relationship which paved the path for the cultural communication between them. Since then "Korean Wave" culture rushed to China along with the acceptance and favor of Korean dramas among Chinese, meanwhile Korean language institutes have mushroomed. However compared to formal Korean language education units Korean language institutes have the following characteristics: large numbers, wide spread, diversity of study motivation and personal situations. Given these reasons; it is imperative to complete statistical analysis on study motivations of language learners in China. Hence this research focuses on a study on Korean language enthusiast learners in a city in China via sampling survey in terms of three aspects. First, individual personal information including gender, age, occupation and study time to find out the basic features of enthusiast learners in Korean language institutes. Second, learning motivation patterns: referring to Gardner & Lam bert`s theory of study motivation in social linguistics contexts. Korean language enthusiast learners` motivation falls into the following two types: integrative motivation and instrumental motivation. Third, study patterns: this parts involves research on learners` study patterns during their spare time which will be divided into survival pattern and academic pattern. This study aims to improve comprehension of the study situation of Korean language enthusiast learners` in China and therefore attributing to the development of Korean language institutes.

중국의 한국어『정독』과목에 대한 요구 분석 -졸업 진로에 대한 요구를 중심으로

교우박 ( Yu Bo Qiao ) 한국문법교육학회 2011 문법 교육 Vol.14 No.-

Korean Language Education has been classified into Minor Language Education at universities in China. Differs from Major Language Education such as English, Korean Language Education however, has unique difficulties including shorter educational time duration, as well as larger educational planned duties. Besides, students have to face lingual influences from Mandarin, English, and even local languages and languages from ethnic groups. Even though, the social reality requires Korean Language students achieving similar advanced level compare with those whom major in English after undergraduate school. One of the most significant questions for discussion in Korean Language Education studies, therefore, should emphasize the way of co-existence of improving teaching efficiency and ensuring quality teaching content. As the subject occupies the largest time duration in Korean Language Education, Intensive Reading therefore, has gained significant impact on improving teaching quality as well as efficiency. In order to improve the efficiency and practicability of Korean Language Education, this article would accurately demonstrate the contents in need for intensive readings, by conducting series of survey researches from students of Korean Language Education from terms of 2007, 2008, and 2009, respectively.