우심방을 침범한 거대 비호지킨씨 림프종 1예

강상범,진승원,이은경,박용현,최용호,김용주,박준철,김재형,홍순조,최규보,권종범,원용순,박건,이은희 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

문화콘텐츠 창작소재로서의 고전문학의 가치에 관한 연구

김용범 한국언어문화학회 ( 구 한양어문학회 ) 2002 한국언어문화 Vol.22 No.-

Kim Yong Bum. 2002. A study on the value of classical literature as the subject matter of culture contents. This study is a research to define the value of coassical novel as the subject matter of culture contents and to grope for high value added of korean culture contents industry. For this purpose, I looked about an instance of a project of an archetype of korean culture's construction. Then I researched relation classical novel contents and information technology. So, I proposed several courses that classical novel is modernized. I hope this article shows the right read for competitive powerful culture industry.

항정신병약물 사용 중인 정신분열병 환자에서 올란자판으로의 교체 방법에 관한 연구(II) : Comparison of Safety 안전성 비교

안용민,권용실,권준수,민성호,박두병,양문정,소형석,송종호,신윤식,우행원,유범희,이홍석,정한용,한창환,김용식 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.5

연구목적: 이 다기관 공동임상연구는 사용 중인 항정신병약물을 ’직접 교체 방법’또는 ’시작-감량 교체 방법’중 한 가지 방법으로 올란자핀으로 교체한 후, 안정성 측면에서 두 교체 방법 간의 비교와 교체후의 변화를 관찰하기 위한 것이다. 방법: 국내 13개 병원의 입원 및 외래에 내원한 환자들 중 ICD-10 지단기준으로 정신분열병에 해당되며, 임상적으로 항정신병약물 교체가 필요한 환자를 대상으로 하였다. 두 가지 교체 방법 중 한 가지를 무작위로 피험자에 적용하였으며, ’직접 교체 방법’에 배정된 경우에는 사용중인 항정신병약물을 일시에 중단하고 10㎎의 올란자핀을 바로 투여하였고, ’시작-감량 교체 방법’에 배정된 경우는 10㎎의 올란자핀 투여하고 2주에 걸쳐서 기존 약물을 감량하여 중단하였다. 올란자핀 사용기간은 총 6주이며, 용량은 5∼20㎎ 범위로 제한하였다. 한정성 평가를 위해서 체중, 생명징후, 자발적인 이상반응 복, 실험실 검사 그리고 Simpson-Angus Scale(SAS), Barnes akathisia rating scale(BARS), Abnormal involuntary movement scale(AIMS). Liverpool University neuroleptic side effect rating scale(LUNSERS)등을 이용하였다. 결과: 총 103명의 정신분열병 환자를 대상으로 하였다. 사용한 올란자핀의 용량, 벤조디아제핀의 병용률, 탈락률과 탈락 사유, 자발적인 이상반응 보고, 생명징후, 실험실 검사 그리고 대부분의 부작용 척도 상에서 임상적으로 의미 있는 차이를 두 교체 방법간에 발견하지 못하였다. 다만 AIMS의 감소는 ’직접 교체 방법’군에서 보다 적었고, 항콜린제의 병용률은 ’시작-감량 교체 방법’군에서 보다 많았다. 기저 상태에서 전체 피험자의 SAS와 BARS 점수는 각각 3.5점과 1.8점이었으며 70% 이상의 피험자가 고프로락틴 혈증을 보였다. 올란자핀으로 교체한 후, SAS, BARS, AIMS 점수의 유의한 감소가 있었으며 고프로락틴 혈증을 보인 피험자 분율도 약 30%이하로 감소하였다. 그러나 교체 방법과 상관없이 올란자핀 교체 후 유의한 체중 증가가 있었다. 결론: 이 연구를 통해 교체 방법에 관계없이 비교적 안전하고 용이하게 올란자핀으로 교체 할 수 있음을 알 수 있었다. 그리고 기존 항정신병약물을 올란자핀으로 교체함으로써 일부 부작용들을 줄일 수 있음을 간접적으로 관찰할 수 있었다. 하지만 이 연구는 여러 제한점과 문제점을 지니고 있기 때문에 보다 체계적인 연구를 통해 검정이 필요하리라 생각된다. Objectives: This multicenter clinical trial involving 13 hospital sites compared the safely of switching to olanzapine between ’direct switching method’ and ’start-tapering switching method’. Method: This study included both inpatients and outpatients who fulfilled the criteria for schizophrenia as defined in the ICD-10, and were in need to be appropriate for switching antipsychotics. Subjects were randomly assigned to one of the two switching methods. For ’direct switching method’group, previous antipsychotics were abruptly discontinued and 10㎎ of olanzapine was administered, and previous antipsychotics was gradually tapered for 2 weeks. Olanzapine was used for 6 weeks and the dose was adjusted within the range of 5-20㎎. The safety of switching to olanzapine was measured with vital sings including body weight, adverse events reported spontaneously, laboratory tests, and various scales such as Simpson-Angus Scale(SAS), Barnes Akathisia Rating Scale(BARS). Abnormal Involuntary Movement Scale(AIMS), and Liverpool University Neuroleptic Side Effect Rating Scale(LUNSERS). Results: 103 patients were switched to olanzapine in this study. The comparison between two switching methods did not show any significant difference in the dosage of olanzapine used, the concomitant use of benzodiazepine, the rate and reasons of drop-out, the adverse events, vital signs, laboratory tests, and most scales for measuring side-effects. However, the decrease in AIMS scores was significantly lower in ’direct switching method’ group, and the concomitant use of anticholinergics was comparatively greater in ’start-tapering switching method’ group. At baseline, SAS and BARS scores were 3.5 and 1.8 points respectively, and more than 70% of the subjects showed hyperprolactinemia. After switching to olanzapine, SAS, BARS, and AIMS scores were significantly decreased and the proportion of the patients with hyperprolactinemia was also decreased to less than 30%. However significant weight gain after the treatment of olanzapine was observed regardless of switching method. Conclusion: This study may suggest that switching to olanzapine can be done with relatively high safety regardless of switching methods and olanzapine can significantly decrease some side-effects induced by other antipsychotics.

담석증과 당뇨병

강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),김경희(Kyung Hee Kim),황용(Yong Hwang),김용범(Yong Bum Kim),이원영(Won Yung Lee) 대한소화기학회 1985 대한소화기학회지 Vol.17 No.2

N/A Most authorities agree the higher incidence of gallstones among diabetic patient. Although many reports on gallstones or diabetes mellitus have been published, and actual correlation between gallstones and diabetes mellitus remains obscure. The purpose of this reports is to know the incidence of gallstone in diabetics and of diabetics in the patients with gallstone. Authors studied prospectively and clinically the diabetics in a group of 173 patients with gallstones and gallstone in a group of 98 diabetic patients who were admitted to Yonsei University Yong-Dong Hospital for the same period of April 1983 to May 1984. The results obtained are summarized as follow: The incidence of gallstone to general admission patients is 1.5% and the prevalence of diabetes mellitus to total in-patients is 0.8% The gallstone was found in 11.0% of diabetics and were diabetic 19.4% of patients with gallstones. The age of peak incidence of gallstones is 5th decade and female was more prevalent than male with the ratio of 1.37:1. The age of peak incidence of diabetes mellitus is 6 th decade and female is less prevalent with the ratio of 0.72:l.3, The most common characteristic finding of patients of gallstones with diabetes mellitus is symptomless(42.1%)4, There is no significant difference in serum levels of cholesterol and triglyceride between diabetic and non-diabetic groups or with and without gallstones. 5. Comparative study on location of stones revealed, 72.8% in gallbladder only, 12.7% in common bile duct only, 4. 6% in intrahepatic duct only, and remainders in multiple site. There is no significant difference in terms of location of stone between diabetic and nondiabetic group.

뇌 아밀로이드 혈관병과 고혈압성 뇌출혈의 감별에 있어서 Apolipoprotein Eε4와 점상 출혈 분포의 유용성

김용범,이광호,이수주,나덕렬,조수진,정진상,이원용 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

춘천지역 도시열섬의 특성과 대기질에 미치는 영향

이종범,김용국,김태우 江原大學校 附設 環境硏究所 1994 環境硏究 Vol.11 No.-

An observational study of urban heat is1and was carried out using field data obtained during 6 day in May and August 1992 in Chunchon(Population size 180,000). Air temperature was measured at 04 points along two sampling routes by thermisters attached to cars, Both routes cover urban and rural area and across the center of urban area, Continuous observation of air sonde was performed to clarify heights of nocturnal boundary layer(NBL) at the center of urban area. Surface meteorological observations were performed at both urban and rural site. This study showed that heat island Phenomena was obvious1y observed at the urbanized area during the night time With low wind Speed. The average NBL heights extended to about 100 meters, but varied with meteorological conditions. After sunset the air temperature decreased with time at both sites and cooling rate at the urban site was Heater than the rural site. The maximum heat island intensity was 7.5°C at 21 LST May 4. Using the two meteorological data gets obtained from urban and rural sites, the air Pollutant concentration was calculated by Gaussian plume model which can obtain not only horizontal distribution of concentration but also vertical distribution. The result indicated that the concentration resulted from urban meteorological data set was lower than that from rural meteorological data set. It was also calculated that the air pollutant extended to higher level in urban meteorological data set than that in rural meteorological data set.

하수 Sludge cakes에 함유된 중금속 분석에 관한 연구

현용범 서울保健大學 1986 論文集 Vol.6 No.1

수영이 비만 여중생들의 혈중 렙틴농도, 지질수준과 체지방률과 미치는 영향

곽용순,김문희,김기범,박온서 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.2

This study was to varify the effects of swimming on leptin level, lipid components (TC, TG, LDL-C, HDL-C) and percent body fat in girl's middle school students during 12 weeks. The subjects of study were divided into obese women group (n=9) and control group (n=9) randomly selected. Exercise intensity of swimming in this study was HRmax 50~80%, exercise duration 50min per day, exercise frequency during 12 weeks. Statistical method for data processing produced mean and SD of total variable. To analyze difference between groups and plasma variables level had executed 2×3 ANOVA. This study was given conclusion as follows: In exercise group, we showed that plasma HDL-C was increased but plasma leptin, TG and LDL-C were decreased during 12wks swimming. Also, %fat were decreased during 12wks swimming.

우리나라 도시지역의 SO₂건성침적 플럭스 산출

이종범,김용국,박일환 江原大學校 附設 環境硏究所 2001 環境硏究 Vol.18 No.-

This study was carried out estimating the dry deposition flux of SO₂at eight urban areas in Korea during one year of 1999. To calculate the deposition flux, deposition velocities were calculated by turbulence parameters estimated from routine meteorological data. Also, hourly averaged SO₂ concentrations which calculated from air pollution monitoring data of each city were used. The dry deposition velocities were mostly higher in the coastal areas than the other areas, which would be caused by relatively strong wind. And, they were high in the daytime because of turbulence activitie. The deposition flux SO₂ is mainly related to the atmospheric concentration. The annual average SO₂ concentration and the deposition flux were 22.62ppb and 1510.52g/㎢/hr at pusan respectively. Also, the flux was higher in winter than other season, which was a significant contribution of exhausted fuel for heating. While the deposition velocity was high to 0.688㎝/sec at Yosu in case of strong wind and small cloud cover, the deposition flux was high to 1597.4g/㎢/hr at pusan in case of weak wind and small cloud cover.

대학교수의 생활체육 참여와 직무만족의 관계

이용식,오연풍,이범제 師範大學 體育硏究所 1997 서울大學校 體育硏究所論集 Vol.18 No.1

The purpose of this study was to examine relation of participation in sport for all and job satisfaction of professors. The subjects of the study were 119 professors who worked at "S" university located in seoul. A questionnaire was designed to measure relation of participation in sport for all and job satisfaction. The questionnaire consisted of three main sections: (a) sochi-demographic characteristics, (b) questions concerning participation in sport for all, (c) job satisfaction. The reliability coefficients of the questionnaire was .7549. The data were analysis with covariance analysis and multiple classification analysis. Results obtained from this research are as follows: 1. Participation in sport for all has positive effect on job satisfaction. 2. The degree (frequency, duration, intensity) of participation in sport for all has no effect on job satisfaction.