65세 이상의 노령층에서 고지혈증의 위험요인

김용배,장원기,황보영,김화성,안규동,이병국,이용진,김세훈,김승수,김승훈,김영록,김웅빈,이성수 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

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납 노출 근로자들에서 ALAD 및 VDR의 다형질성이 조혈기능 지표에 미치는 영향

이성수,김남수,김진호,김용배,황보영,김화성,안규동,이병국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Objectives: This study was conducted with new workers who entered lead industries from 1992 to 2001 to evaluate the genetic susceptibility of ALAD (δ-aminolevulinic acid dehydratase) and VDR (vitamin D receptor) gene on health effect of lead exposure. Methods: Among the subjects of the database of lead industries at the Soonchunhyang University Institute of Industrial Medicine, only new workers were selected for this study. The total of eligible workers for this category was 3,540 workers, including non lead exposed workers of same lead industries. From stored blood in specimen bank of Soonchunhyang University, genotype of ALAD and VDR were measured using PCR method. Variables for this study were blood lead as an index of lead exposure, ZPP (zinc protoporphyrin in blood), urine ALA (δ-aminolevulinic acid), and hemoglobin as an index of hematopoietic effect of lead. Information on sex, job duration, and weight were collected for personal information. The data were analyzed using SAS (version 8.2) with descriptive analysis of t-test and multiple regression analysis. Results: Among 3,540 new employed study subjects during period of 1992-2001, 3,204 workers (90.5%) had ALAD genotype 1-1, while 336 workers (9.5%) had variant type of ALAD (1-2 or 2-2). For VDR genotype, 2,903 workers (89.7%) out of total tested 3,238 workers were belonged to type bb and 335 workers (10.5%) were type bB or BB. The distribution of genotype of ALAD and VDR were not different according to the job duration in male workers, but were different in female workers. The effect of ALAD and VDR genotype on blood lead were positively significant in the analysis of all cumulative data of new employed workers for 10 years. The effect of VDR genotype on blood lead were stronger than that of ALAD While the variant ALAD gene made decrease of mean ZPP and ALA in urine after controlling for blood lead and other covariate, the variant VDR gene made increased the mean ZPP and ALA in urine in all cumulative data analysis and cross sectional analysis by job duration. For hemoglobin, ALAD and VDR genotype did not affect the mean value. Conclusions: From the above our results, we found that ALAD and VDR genotype exerted significant effect in various way. We confirmed that the finding of a cross sectional study of protective effect of variant ALAD on the effect blood lead on blood ZPP in our retrospective study design. It was found that VDR did not exert protective effect for lead exposure as the variant ALAD did.

연쇄중합효소반응을 이용한 태아성별진단

이희섭,김용신,김화선,김정중,김원신 원광대학교 생명공학연구소 1996 생명공학연구소보 Vol.4 No.1

For sex determination by the PCR method, oligoprimers to Y-chromosome gene, DYZ1, SRY, and AMGL were synthesized and genomic DNA was extracted from male and female placenta for the control use. DYZ1 represented 154 bp single band to 0.001pg/ml male genomic DNA but did not represent 154 bp band in female genomic DNA, SRY represented 341 bp band to 1 pg/ml male genomic DNA but did not represent 341 bp band in female genomic DNA, and AMGL represented 977 and 788 bp double band to 1 pg/ml male genomic DNA and 977 bp single band to 1 pg/ml female genomic DNA in 2% agarose gel electrophoresis stained with ethidium bromide. DYZ1 was 1,000-fold sensitive than SRY and AMGL. DYZ1 and SRY could not identify the PCR failure from female but AMGL identified. To increase the sensitivity, the dual amplification of AMGL was performed and the sensitivity increased to 1,000-fold. During the dual amplification of female genomic DNA mixed with male genomic DNA, 0.00125pg/l, 1:400 part male genomic DNA contamination represented double bands as male. In 2 cases of 46, XY female, DYZ1 and AMGL amplification represented male band but SRY amplification did not represent male band. It was suggested that SRY gene was deleted in two 46, XY female cases. for fetal sex determination, PCR with DYZ1, SRY, and AMGL was performed in 10 cases of chorionic villi and 15 cases of amnionic cells. By the comparison with karyotyping result, fetal sex determination was achieved successfully in all 23 samples using PCR of SRY and AMGL but false result was detected in 3 cases(13%) using DYZ1. According to our results, it was concluded that DYZ1 was 1,000-fold sensitive than SRY and AMGL but could not be used because of its false results, and AMGL and SRY must be used concomitantly for precise sex determination.

경련성 환아 부모들의 인식에 대한 연구

이경화(Kyoung Hwa Lee),서은숙(Eun Sook Suh),김영창(Yong Chang Kim),김창휘(Chang Hwi Kim),이동환(Dong Whan Lee) 대한소아신경학회 1996 대한소아신경학회지 Vol.3 No.2

Convulsive disorder is the most part of the pediatric neurologic disease. As far as the treatment of convulsive disorder concerned, we must consider familys' understanding, and the close cooperation between the epileptic child, parents, and doctors. We compared to Kim's report in 1985, to study the change of parents of epileptic children thinking. A prospective study was undertaken the analysis of 100 epileptic children parents visited to the pediatric dept, of Soonchunhyang university hospital from May to July, 1995. Psychological assessment, questionnaires which contains 17 items were given them, and these items were compared to Kims report in 1985 The results were as follows: 1) Parents of epileptic children answered convulsive disorder has influenced to children growth and development( 60.8% in 1985, 65.0% in 1995 ). 2) For asking the causes of children disease, 40.5% of them in 1985 and 50.0% of them in 1995 answered to uncertain, but only 7.8% of them in 1985 and 7.0% of them in 1995 answered to relation with familial inheritance. 3) The feelings at time of the diagnosis were gloomy or uncomfortable: 52.3% in 1985, 38.0% in 1995 and shameful 28.1% in 1985, 9.0% 1995. parents had belived in the epilepsy was treatable disease: 41.0% in 1995. 4) According to the this survey, patients explained reasons why their children take the medication increased from 23.5% in 1985 to 65.0% in 1995. 5) Only family, knew that their children had the convulsive disorder about 50.3% in 1995 and 22.0% in 1995. Family, patients and other people except family knew that their children had the convulsive disorder about 6.5% in 1985 and 43.0% in 1995. 6) The parents opinion and expectation toward the medical doctors were that they wanted to get full explanation for the disease 81.0% in 1985 and 35.1% in 1995, and others were explantation about toxicity and side effects of the medication and advises for the childrens life and activities.

축산분뇨 혐기소화 잔재물의 특성 및 초지 적용성 평가

김승민(Seung Min Kim),정웅기(Woong-gi Jung),성용주(Yong Joo Sung),안희권(Hee-Kwon Ahn),김동성(Dong Sung Kim),윤도현(Do-Hyun Yoon),김동섭(Dong-Seop Kim1),정광화(Hwa Gwang Jung) 한국펄프·종이공학회 2014 펄프.종이기술 Vol.46 No.3

근로관계와 경영권의 법적성질에 관한 연구

金龍華,金範基 호남대학교 2005 호남대학교 학술논문집 Vol.26 No.1

Employment relations are established on the basis of an employment contract in principle, closely related each other and at the same time are legal relations that bind mutually. Furthermore, a management right and unityㆍcollective action right are mutually restricted relations. With the realization of democratization of labor-management relations, the use of the right has been developed into accepting mutual limitation. Although unity action was only activity of citizens' collective expression in the level of civil laws, it could have legal approval of special protective exemption in an aspect of labor laws through an amendment to a principle of civil laws. Its objective is to secure criminal and civil exemption of union activity and to prohibit unifair labor action, which is originally implied in the constitution. Accordingly, interpretation theory that distinguishes unity action from the beginning cannot be accepted. It is because both a strike and unity action by agreement pursue a common goal to realize the value of right to live. Employment relations are formed on the basis of the mutual rightㆍobligation of employer and employee. While employees have the obligation to provide agreed labor in employment relations, an emloyer has a claim to provide labor against employees in principle. Employer's right to use or dispose employees' labor as a company manager for the purpose of business can be acquired by contract with employees. There is no way to dispose such labor in employer's own right free from such contract relations. Employees should obey employer's command and order in the process of providing labor and follow manager's measures to maintain management facilities and order. In the words, employees should provide labor according to employer's right to command labor that is specific indication of a claim to provide labor, and at tne same time observe management order based on employer's right to own management facilities and to control facilities. On the other hand, the concept of a management right is employer's own right. Although a precedent admits it as a legal right, it cannot be admitted as a right based on the positive law. But its scope of execution as a decision making right reserved to an employer also is limited to legal matters. While some deny the existence of a management right on the basis of its fail to prescibe specifically in constitution or laws like the trade union right, others argue that a management right should be admitted as a nature right because an organizational consistency must be maintained with the management of a property right, considering that constitution ensures it as a property right. Manger's right of management is economic power that controls land, labor, wealth, or company production and may be understood as a series of right of property operation that a manger(capitalist) owns means of production, combines them organizationally, and conduct production activity. Moreover, today a capital has been separated from management. Managers should be responsible for company's environment and have the function to fulfill the responsibility as their own right. Some argue that it is managers' exclusive decision matters that do not need to discuss in collective bargaining, which is called a management right. Such a management right is company's own function and governs labor-managemant relations. However, the problem is whether there is manger's management right correspondent to employees' labor right. While the trade union right is expressly stipulated in the text of constitution or labor relations laws, a management employment relations and its relations with a management right, and the legal meaning and nature of a management right, which is very important in the right of the establish modern characteristics of labor-management right and the concept of a management right that meets in reailty.

클로렐라가 카드뮴-유인 rat 혈중지질의 변화와 간장해에 미치는 영향

김용호,이용우,이소진,박화진 한국노화학회 1998 한국노화학회지 Vol.8 No.3

모험기업의 라이프 싸이클 단계별 재무전략

김재명,오정화,손재영,최용훈 강원대학교 석재복합신소재제품연구센터 1997 석재연 논문집 Vol.2 No.-

본 논문은 신제품의 사업화와 관련한 모험기업의 라이프 싸이클 단계별 재무전략, 특히 자금조달 전략에 관해 연구하였다. 특히 금융상품의 유형과 특성을 자본원천별로 분석하고, 이에 기초하여 모험기업의 성장단계별 자금조달전략을 제시하였다. 본 논문은 라이프싸이클을 4단계로 나누고, 각 단계별 재무특성과 자금원천의 특성을 고려하여 라이프싸이클 단계별 자금조달원천 행렬표를 제시하였다. 이에 따르면 모험기업은 라이프싸이클 단계별로 개인저축, 에인젤, 모험자본, 동업자, 기업공개, 그리고 잉여금 등의 지분자본원천과 회사채, 거래신용, 자산기초금융, 은행이나 보험회사 차입, 그리고 정책지원자금 등 부채자본원천을 중첩하여 자본조달원천으로 사용할 수 있음을 보여주고 있다. This paper discusses the relationships between stage of development in venture business life cycles and financial strategies. The paper selectively examines the study by reviewing the characteristics of the various finacial instruments on the basis of the cash flows of venture business life cycles. I suggested the source of capital matrix combining the various sources of capital. At each stage, the venture businessess should raise the funds by using the various combinations of sources of equity financing and debt financing.

전상회계 전자교재(e-Textbook) 개발에 관한 연구

김소형,정용화 한국직업능력개발원 2003 직업능력개발연구 Vol.6 No.1

This study researched to apply a accounting education method of the future that to consider college environment. The research model was completed to be analysis a concept, strong-weakness of e-Book & e-Text Book, environment factor for development of accounting e-textbook. The contents development used to the effect of animation and made the simple design. It was to be purposed to study an important accounting knowledge fast. The accounting e-textbook was made to use the PC and internet explore for convenient the students. This method learn anywhere the computer accounting program.

빈랑자 추출물의 염색성 및 기능성에 관한 연구

김지선,조용석,최순화 대한가정학회 2003 Family and Environment Research Vol.41 No.7

Recently there has been interested in the use of natural dyes in textile applications. Generally natural dyes can exhibit better biodegradability and have a higher compatibility with the environment. In this study, cotton wool and silk fabrics were dyed with alkali extract of Arecae semen using various mordants, and their dyeabilities were discussed. Additionally the fastness to washing, perspiration, light, rubbing, and drycleaning and UV-B protection rate were also investigated. Cotton, silk and wool fabrics dyed with alkali extract of Arecae semen were colored in reddish yellow tint. The optimum dyeing condition of the colorants extracted from the Arecae semen was three repeated dyeing at 95℃ for 1.5hrs. The dyed fabrics by using mordanting methods improved the fastness to washing, perspiration and drycleaning, but the fastness to light and rubbing were not increased. The UV-B protection rate of the wool fabrics were increased by dyeing with extract of Arecae semen.