Protective Effects of N-acetylcystenine and Selenium against Doxorubicin Toxicity in Rats

Yeo-sung Yoon,Sun-don Kim,Min-hye Lee,Heung-shik S.Lee,In-se Lee,Je-kyung Sung,Eun-sung Park 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

Effects of N-acetylcysteine and Selenium against Doxorubicin Toxicity in RatsEun-sung Park, Sun-don Kim1, Min-hye Lee, Heung-shik S. Lee, In-se Lee, Je-kyung Sung and Yeo-sung Yoon*

급성 호흡곤란 증후군으로 발현된 폐결핵 1례

윤여준,박성우,이준혁,장안수,박춘식 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Pulmonary tuberculosis as a cause of the acute respiratory distress syndrome is quite rare. The diagnosis of acute respiratory distress syndrome due to pulmonary tuberculosis is difficult because of the diversity of radiological patterns. The ability to identify patients at risk for the acute respiratory distress syndrome is important if therapies are to be developed to prevent the disorder. We experienced a young female compliants with mild fever, dyspnea who diagnosed pulmonary tuberculosis 1 months ago. She stoped anti-tuberculosis medication 2 day because confirmation of drug fever and after then sudden aggravated dyspnea. The clinical course of this case is similar with presentaion of ARDS. We started antituberculosis medication with steroid, which result in good prognosis.

분심기음의 항암작용 및 면역기능에 관한 연구

여대원,김진성,윤상협,류봉하,류기원 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

This study was performed to investigate the effect of Bunsimgieum on antitumor effect after sarcoma-180 cells transplantation into peritoneal cavity or left groin and immune responses on the depressed immunity induced by methotrexate in mice. The Bunsimgieum extract of 10㎎/㎏ was orally administered 14 days for antitumor effects and 21 days for immune responses. 50% inhibitory concentration(IC_(50)) of SUN-1, SUN-C4. and SUN-396 cancer cell, mean sunvival days and body weight of tumor bearing mice, and growth of tumor mass for antitumor effect; delayed type hypersentivity, hemagglutinin titer, hemolysis titer, rosette forming cells, natured killer cell activity, lymphocyte transformation. productivity of interleukin-2 and phagocytic activity for their immune responses were measured in ICR mice. Significance in antitumor effect is noted in the enlongation of mean life days and inhibition of tumor growth(p<0.01 respectively). Significance of immune responses is also noted in hemolysis titer, lymphocyte transfumotion IL-2 productivity, phagocytic activity, and natural killer cell activity at E/T ratio 100 : 1(p<0.01, respectively). Significant in rosette cell formation was seen dosage of 20㎎/㎏(p<0.01) However, Difference of body weight as antitumor effect, delayed type hypersensitivity, and hemagglutinin titer were not shown significantly. According to the above results, it could be suggested that Bunsimgieum has prominent antitumor and immunity enhancing effect.

상악골에 발생한 악성섬유성조직구종의 치험례

이상철,김여갑,류동목,이백수,윤옥병,신민철 大韓顎顔面成形再建外科學會 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.1

越鞠丸과 七氣湯이 白鼠의 實驗的 胃潰瀁에 미치는 影響

尹泰汝,文相元 대한본초학회 1988 大韓本草學會誌 Vol.3 No.1

Wolgukwhan and Chilkitang have been applied to the abdominal pain and neurosis caused by the disharmony of circulation of vital energy. This studies were undertaken in an attempt to investigate the effect of secreting volume of gastrie juice, gastric acidity and gastric ulcer induced by Shay's ulceration, stress in rats. The results were as follows. 1. Wolgukwhan and Chilkitang showed a significant inhibitory effects on on the secreting volume of gastric juice, gastric acidity in rats, and Chilkitang revealed better results than Wolgukwhan. 2. In the case of the ulcer index of Shay's ulceration in rats Wolgukwhan and Chilkitang were decreased, and Wolgukwhan showed remarkable antiulceration effect than Chilkitang. 3. The effect of Wolgukwhan and Chilkitang on gastric ulcer inuced by stress in rats were shown a significant anti-ulceration, and Chilkitang was more effective than Wolgukwhan. According to above results, Wolgukwhan and Chilkitang were assumed to be effective on neurogenic gastric ulcer.

상아질 결합제가 컴포머의 불소유리에 미치는 영향에 관한 연구

윤여상,김종수,권순원,김용기 대한소아치과학회 2001 大韓小兒齒科學會誌 Vol.28 No.2

본 연구의 목적은 와동 충전시 충전재와 지질 사이에 개재되는 상아질 결합제가, 수복물에서 유리되는 불소가 와동 벽으로 침투하는 과정에 어떠한 영향을 주는지를 조사함이었고, 부가적으로 레진 강화형-글라스 아이오노머 시멘트의 접착에도 상아질 결합제를 도포하는 것이 체질과의 결합력을 강화시킬 수 있는지에 대해 평가하고자 하였다. Fuji II LCR와 Dyract APR를 선정하여 상아질 결합제의 도포 여부에 따른 불소 유리량 측정과 전단 결합 강도도를 비교분석하였으며, 치질 내로의 불소 침투 양상은 교환 시기에 있는 재2유구지에 Fuji II LCR와 Dyract APR를 충전하고 3주내에 발거하여 EPMA필 분석하였다. 상아질 결합제는 불소 유리량을 현저하게 감소시키는 것으로 나타났으며(p<0.05) Fuji II LCR의 경우 상아질 결합제의 도포가 결합강도를 증가시키지 못하였다. EPMA분석결과 상아질 결합제는 충전재로부터 유리되어 나오는 불소가 치질 내로 확산되는 것을 방해하는 것으로 확인되었다. It is well known that glass-ionomer cement and compomer can release fluoride which can inhibit the progresion of dental caries. The purposes of thins study were to evaluate whether the fluoride from fluoride-containing ailing materials can penetrate the dentin bonding adhesive and the dentin bonding adhesive can increase the bond strength of resin-modified glass lonomer. The amount of fluoride release from resin-modified glass lonomer and compomer was measured during 28 days of period find statistically analyzed by t-test. The bond strength of each material with/without dentin bonding adhesive was measured and also statistically analyzed by t-test. The distribution of fluoride from each material into the tooth was explored by electron probe microanalysis system (EPMA). The expenmental teeth used were second primary molars about to exfoliate. The amount of fluoride from each material was diminished by dentin bonding adhesive during 28 days(p<0.05) and the bond strength was not increased by dentin adhesive in resin-modified glass ionomer. The bond strength of group VI was not detectable. The distribution of fluoride from earth material into teeth was according to dentino-enamel junction and dispersed into pulp from pulpal floor. The widest distribution was shown in resin-modified glass ionomer cement filled without the application of dentin bonding adhesive.

STI571 (Glivec^(�))에 의하여 빠른 치료 반응을 보인 불응성 Gastrointestinal stromal tumor

윤경원,이제중,김여경,황호인,이병환,조상희,정익주,김형준 全南大醫大 2001 전남의대학술지 Vol.37 No.4

공구마멸 감시에 음향방출 신호를 이용하기 위한 연구

윤종학,여만구,김상헌 한국공작기계학회 1996 한국생산제조학회지 Vol.5 No.3

This study is focused on the prediction of appropriate tool life by clarifying the correlation between progressive tool wear and AE(Acoustic Emission) signals, while cutting stainless steel by end mill on te machining center. The results of this study were that RMSAE tends to increase linearly along with the incrase of the cutting speed, and it was more sensitive to depth of cut than to the variation of feed rate at the same cutting conditions, and RMSAE increases around 0.21mm flank wear hereby AE-HIT also increases. AE signals depend upon tool wear and fracture from the above results. Therefore, the AE signals can be utilized in order to monitor the tool condition.

북한이탈주민에 대한 정착교육 평가 및 방향

윤여상 대구대학교 사회과학연구소 2004 社會科學硏究 Vol.12 No.1

북한이탈주민들은 하나원 교육과 정부의 정착지원 체계에 대하여 대체로 만족감을 보이고 있다. 그러나 북한이탈주민의 생활환경은 매우 좋지 않은 것으로 나타난다. 특히 남한사회 적응의 가장 중요한 부분을 차지하는 경제적응과 심리적응은 상대적으로 낮은 상태이다. 북한이탈주민 정착을 위한 정책의 주요 사항은 입국증가에 대한 대처능력 확보, 초기 정착의 고비용 저효율 시스템 개선, 자립정착 의지 제고로 요약될 수 있다. North Koreans in South Korea are mostly expressing satisfaction towards government's resettlement and support system as well as Hanawon training. But life standards of North Koreans in South Korea indicate poor situation. In particular, economic and mental adjustment which take very important portions of their adjustment in South Korea are in relatively low level. Major issues for North Korean resettlement policy are reinforcement of ability to manage increasing arrival of North Koreans, improving high-cost low-efficiency system for early resettlement, and promotion of self-reliance in resettlement.

사용후핵연료 차세대관리공정 장비의 내방사선 요건 분석

김성영,송태길,윤지섭,정운관,여화연 조선대학교 에너지.자원신기술연구소 2003 에너지·자원신기술연구소 논문지 Vol.25 No.1

For hot operation of advanced spent fuel conditioning process(ACP), the analysis of radiation-resistant Requirements effect and the system design process are required to design equipment to operate to operate reliably in a gamma radiation environment such as hot cell. To analysis the effects of radiation for ACP, we used the SCALE codes which were certified by Nuclear Regulatory Commission(NRC). The source term was calculated which reflects the features of target nuclear fuels using ORIGEN-S, a module of the SCALE code, and the gamma dose rates were calculated by using the QADS modules, considering the geometry of process equipment respectively. the results are shows that the value was maximum 3.03 ㏉/h from the rod storage box in hot cell, maximum 0.6 ㏉/h from the metallizer, and maximum 72.0 ㏉/h from the vol-oxidizer. Considering those values, the design methods for shielding and repositioning the major equipments and components should be induced, and, the preventive maintenance for components before failure actually occurs should be minimized the effects of radiation.