법정에서의 구술심리 현황과 활성화 방안

이세인 ( Se In Lee ) 고려대학교 법학연구원 2009 고려법학 Vol.0 No.52

According to a lawyer survey conducted by the author, it was possible to divide the different opinions of the lawyers regarding in-court oral argument into two categories. One group of lawyers said that although they want to make oral argument actively in court, the court is not awarding enough opportunity. The other group said that the court is forcing them to make oral argument when they do not want to make them. The lawyers have different thoughts about oral argument because their personalities, the circumstances they work in, and the cases they handle are different. The important thing is that the court should provide the lawyers who want to make oral argument enough opportunity. If it is true that oral argument provides positive effect in trial proceedings, the lawyers who make good oral arguments will succeed in legal society, but the lawyers who cannot make good oral arguments will not be able to play leading roles. It is up to the lawyers to choose to make oral argument, and the court should give enough opportunity to the lawyers who choose to make oral argument. Since each court has its own way of leading oral argument at present, the court should provide guide to the parties on how to prepare their oral arguments. Moreover, there are things to be changed or improved in Korean trial practice in order to encourage oral argument. Trial must be concentrated into one to two days, leading questions in witness examination should be limited, and court record should contain exact content of the oral argument. Also, more time for each trial hearing should be provided by increasing number of judges and court employees. Oral argument provides procedural satisfaction to the parties and helps to reach a conclusion through finding of facts. In order to achieve these objectives through oral argument, prosecutors, attorneys, judges and court staff must cooperate and work together. The author hopes that the new law school system in Korea helps the future lawyers to improve their oral presentation skills and to have positive attitude about making oral argument in court.

Screening with the Korean Version of the Mood Disorder Questionnaire for Bipolar Disorders in Adolescents: Korean Validity and Reliability Study

Se-Hoon Shim,Jong-Hun Lee,Jye-Heon Song,Beomwoo Nam,Bo-Hyun Yoon,Ha-young Jin,Hyung-Mo Sung,Jong Hyun Jeong,Sae-Heon Jang,Duk-In Jon,Young Sup Woo,Won-Myong Bahk 대한정신약물학회 2018 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.16 No.3

Objective: This study aimed to evaluate the validity and reliability of a Korean version of the Mood Disorder Questionnaire-Adolescent version (K-MDQ-A) as a screening instrument for bipolar disorders in adolescents. Methods: One hundred two adolescents with bipolar disorders and their parents were recruited from November 2014 to November 2016 at 7 training hospitals. One hundred six controls were recruited from each middle school in two cities of South Korea. The parent version of the original MDQ-A was translated into Korean. The parents of all participants completed the K-MDQ-A. The diagnoses of bipolar disorders were determined based on the Korean version of K-SADS-PL. The test-retest reliability with a 10-month interval was investigated in 33 bipolar adolescents. Results: K-MDQ-A yielded a sensitivity of 0.90 and a specificity of 0.92 when using a cut-off score of endorsement of 5 items, indicating that symptoms occurred in the same time period and caused moderate or serious problems. The internal consistency of the K-MDQ-A was good. The correlations between each item and the total score ranged from 0.40 to 0.76 and were all statistically significant. Factor analysis revealed 3 factors that explained 61.25% of the total variance. The mean total score was significantly higher in bipolar adolescents (7.29) than in controls (1.32). The Pearson correlation coefficient for the total test-retest score was 0.59 (p<0.001). Conclusion: The K-MDQ-A completed by parents showed the excellent validity and reliability and may be a useful screening tool for adolescents with bipolar disorders attending in- and outpatient psychiatric clinics.

Power Generation Using Magnetic Nanofluids in Millimeter-Sized Channel With In-Phase Mode of Magnetization

In-Ho Kim,Jong-Chul Lee,Sangyoup Lee,Geun-Young Jeong,Se-Hee Lee IEEE 2015 IEEE transactions on magnetics Vol.51 No.11

<P>Magnetic nanofluids (MNFs) are an interesting energy harvesting source. In this paper, the flow energy harvesting was experimentally and numerically investigated in a millimeter-sized channel using an externally applied permanent magnet to control the magnetizing direction of the magnetic nanoparticles (MNPs). Oil- or water-based MNF includes a certain percentage of magnetized nanoparticles and has unique features that vary with the strength of the external electromagnetic field. When the MNF flows through a cross-sectional area of the coil loop, the electromotive force can be obtained by following Faraday's law, because the MNPs act as permanent magnets. When the MNFs are used for flow energy harvesting, the main issue is the in-phase mode alignment of the MNPs magnetization with the coil loop. Without the in-phase mode, the electric power cannot be generated, because the net magnetization of the MNF is zero. Most of the previous research works, however, have not considered it. Thus, to implement this mode, we proposed an externally applied magnetic field generated by a cylindrically shaped permanent magnet. Short and closed Teflon tubing with a 1.5 mm inner diameter, containing the MNF, was located inside long silicon tubing and moved along the positive and negative directions by a pump. Then, the generated voltages were measured, and exhibited similar results to those obtained analytically. In the same way, we calculated and experimentally tested a chain type of Teflon tubing.</P>

자기기록식 3일간의 24시간 회상법의 신뢰도 연구 : 서울지역 중년 자원자를 대상으로

이미숙,우미경,김성애,오세인,곽충실 대한지역사회영양학회 2003 대한지역사회영양학회지 Vol.8 No.4

This study examined the reproducibility of nutrient intakes estimated by the 24-hour recall method in a prospective cohort study (Longitudinal study of aging and health monitoring of Korean elderly) of middle-aged volunteer subjects (42 males and 49 females) in the Seoul area. The three-day 24-hour recall was administered twice at an interval of approximately 6 months. The first data were collected and a corrective procedure was performed by interviewing of the subjects and a trained dietitian. The second data were collected by mail from the subjects without the performance of any corrective procedure. The mean age of the subjects was 53.5 ± 9.6 for the males and 52.2 ± 8.9 for the females. The subjects who had above college education were 95% in the case of the males and 60% in the case of the females. The characteristics of the male subjects in this study were that they were highly educated and held professional jobs and were from the middle or upper class. Comparing the first and second 24-hour recall data, the second data showed relatively lower intakes of all nutrients, except vitamin A, vitamin B₁ and cholesterol. There was no difference in the nutrients of the first and the second data with respect to vitamin A, vitamin B₁ and cholesterol in the males and calcium, iron, sodium, vitamin A, vitamin B₁, vitamin B₂ and cholesterol in the females. This data may indicate that the 24 hour recall method without a dietitian's help may result in lower reporting of the subject's intakes. The men had a tendency to remember less than the women. Pearson's correlation coefficients with unadjusted nutrient intakes values were ranged from 0.24 to 0.66. When energy intake was adjusted, there was a slight increase (from 0.26 to 0.71). Intra-class correlation coefficients with nutrient-unadjusted values ranged from 0.22 to 0.66, and the energy-adjusted values were ranged from 0.23 to 0.69. The weighted kappa statistical values ranged from 0.10 to 0.40. On the average, 46.3% of the subjects who were found in the lowest quartile of the nutrient intake levels based on the first 24-hour recall, were in the lowest quartile based on the second 24-hour recall. Therefore, there was a low reproducibility between the first and the second 24-hour recall. We should examine the factors influencing low reproducibility. Also, strategies should be developed to maximize the reliability of the assessment, with regard to portion-size training and telephone validation.

Comprehensive Evaluation of the NeoBase 2 Non-derivatized MSMS Assay and Exploration of Analytes With Significantly Different Concentrations Between Term and Preterm Neonates

Lee Beomki,Heo Won Young,Kim Jee Ah,Lee Hyun-Seung,Hwang Narae,Park Hyung-Doo,Sung Se In,Chang Yun Sil,Park Won Soon,Lee Soo-Youn 대한진단검사의학회 2023 Annals of Laboratory Medicine Vol.43 No.2

Background: Despite the popularity of the NeoBase 2 Non-derivatized MSMS assay (PerkinElmer, Turku, Finland), there are no reports of its comprehensive evaluation, including the ability to distinguish transient tyrosinemia of the newborn (TTN) from tyrosinemia type 1 (TYR 1) using succinylacetone (SUAC). No newborn screening (NBS) cutoffs for preterm neonates in the Korean population have been suggested. We evaluated the NeoBase 2 assay and identified analytes requiring different cutoffs in preterm neonates. Methods: Residual NBS dried blood spot samples and proficiency testing (PT) materials of the Newborn Screening Quality Assurance Program and the Korean Association of External Quality Assessment Service were used. Precision, accuracy, limit of detection (LOD), lower limit of quantification (LLOQ), linearity, recovery, carryover, and performance of SUAC were evaluated. Cutoffs were determined, and analytes requiring different cutoffs in preterm neonates were investigated. Results: Mean CVs for within-run and between-day precision were within 15%. Accuracy analysis indicated high agreement with in-house derivatized assay results and results of other PT participants. All analytes demonstrated acceptable LOD, LLOQ, and linearity. Recoveries were acceptable, except for SUAC. Carryover was negligible. Cutoffs were established for all analytes; Tyr, adenosine, and C20:0-lysophosphatidylcholine required different cutoffs in preterm neonates. Differential diagnosis of TYR 1 and TTN was successful with simultaneous Tyr and SUAC measurement. Conclusions: The NeoBase 2 assay demonstrated satisfactory performance. The additional analytes provide a wider diagnostic coverage, and the simultaneous measurement of Tyr and SUAC is efficient in excluding TYR 1. The new cutoffs for preterm neonates may decrease false-positive rates, without compromising diagnostic sensitivity.

Low-Dose Persistent Organic Pollutants Impair Insulin Secretory Function of Pancreatic β-Cells: Human and In Vitro Evidence

Lee, Yu-Mi,Ha, Chae-Myeong,Kim, Se-A,Thoudam, Themis,Yoon, Young-Ran,Kim, Dae-Jung,Kim, Hyeon-Chang,Moon, Hyo-Bang,Park, Sungmi,Lee, In-Kyu,Lee, Duk-Hee American Diabetes Association 2017 Diabetes Vol.66 No.10

<P>Low-dose persistent organic pollutants (POPs), especially organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), have emerged as a new risk factor for type 2 diabetes. We evaluated whether chronic exposure to low-dose POPs affects insulin secretory function of beta-cells in humans and in vitro cells. Serum concentrations of OCPs and PCBs were measured in 200 adults without diabetes. Mathematical model-based insulin secretion indices were estimated by using a 2-h seven-sample oral glucose tolerance test. Insulin secretion by INS-1E beta-cells was measured after 48 h of treatment with three OCPs or one PCB mixture. Static second-phase insulin secretion significantly decreased with increasing serum concentrations of OCPs. Adjusted means were 63.2, 39.3, 44.1, 39.3, 39.7, and 22.3 across six categories of a summary measure of OCPs (P-trend = 0.02). Dynamic first-phase insulin secretion remarkably decreased with increasing concentrations of OCPs among only insulin-sensitive individuals (P-trend = 0.02); the insulin levels among individuals with high OCPs were approximate to 30% of those with low OCPs. Compared with OCPs, PCBs showed weaker associations. The decreased insulin secretion by INS-1E beta-cells was observed for even 1 pmol/L OCP. The data from human and in vitro cell experiments suggest that chronic exposure to low-dose POPs, especially OCPs, can induce pancreatic beta-cell dysfunction.</P>

한우 난소에서의 angiogenin분포와 mRNA발현에 관한 연구

이흥식,이인세,강태천,서제훈,송승훈 대한해부학회 1999 Anatomy & Cell Biology Vol.32 No.1

간경변증 환자의 정신과적 특성 및 아임상적 간성뇌병증 진단을 위한 연구 : 인지기능 및 유발전위를 중심으로 Cognitive Functions and Evoked Potentials

유승호,이소영,김진세,변관수,정인과 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.5

연구목적 : 본 연구는 명백한 간성뇌병증이 없는 간경변증 환자에서 불안, 우울기분 및 삶의 질 등 정신과적 특징과 신경심리학적인 결손의 양상을 밝히기 위해서 고안되었다. 그리고 아임상적 간성뇌병증의 평가에서 체성감각 유발전위 검사의 역할을 연구하고자 하였다. 방 법 : 간경변증으로 진단된 41명의 환자군과 정상 대조군 31명을 대상으로 하였다. 이들에서 우울기분 및 불안을 평가하기 위해 Beck Depression Inventory와 State & Trait Anxiety Inventory를 시행하였고 삶의 질의 평가를 위해 Health-related Quality of Life Questionnaire를 시행하였다. 또한 어휘검사, 숫자외우기 검사, 토막짜기 검사, 숫자기호 바꿔쓰기 검사 및 선로잇기 검사 A와 B 등 간단하지만 포괄적인 인지기능검사를 시행하였다. 또한 41명의 환자군 중에서 인지기능검사 결과에 의거하여 분류된 13명의 아임상적 간성뇌병증군(SHE군)과 11명의 아임상적 간성뇌병증이 아닌 간경변증 환자군(non-SHE군) 그리고 8명의 정상 대조군에서 체성감각 유발전위를 측정하였다. 결 과 : 간경변증 환자는 정상인에 비해서 우울기분과 특성불안이 유의하게 증가하였다. 또한 건강과 관련된 일상생활의 삶의 질의 수준이 정상인보다 저하되었고, 특히 주의력과 각성이 요구되는 행동에서 수행이 저하되었다. 또한, 간경변증 환자는 숫자기호 바꿔쓰기 검사와 선로잇기 검사에서 정상 대조군보다 저하된 수행을 나타내었다. 또한 이러한 인지기능검사를 통해서 진단한 아임상적 간성뇌병증군에서 6개월 추적조사를 하였을 때, 명백한 간성뇌병증의 빈도가 아임상적 간성뇌병증이 아닌 군보다 유의하게 높았다. 체성감각 유발전위 소견은 N65 잠복기와 N20-N65 IPL의 경우 SHE군, non-SHE군 및 정상 대조군 사이의 유의한 차이가 있었다. 특히 N65는 SHE군만이 정상 대조군과 유의한 차이가 있었고 N95는 숫자기호 바꿔쓰기 검사 및 선로잇기 검사 A와 유의한 상관관계가 있었다. 결 론 : 간경변증 환자에게 우울 및 불안 등 정서적인 어려움에 대한 실제적인 관리 및 삶의 질을 높일 수 있는 치료적 접근이 고려되어야 하겠다. 또한 숫자기호 바꿔쓰기 검사와 선로잇기 검사가 아임상적 간성뇌병증의 조기 진단에 민감하고 유용한 도구로 생각되어 간경변증 환자에서 정례적으로 적용시키는 것이 간경변증 환자의 관리에 도움을 줄 수 있을 것으로 생각된다. 마지막으로, 본 연구에서의 체성감각 유발전위 소견은 간경변증 환자에서 아임상적 간성뇌병증 환자의 진단 및 연구에 중요한 의미를 지닌다고 생각된다. Objectives : This study was designed to elucidate the psychiatric characteristics and nature of the neuropsychological deficits associated with subclinical hepatic encephalopathy(SHE) in patients with non-alcoholic liver cirrhosis. And also the authors prospectively studied the role of somatosensory evoked potentials(SEP) in the assessment of SHE. Methods : Beck Depression Inventory(BDI) for measuring depression, State Trait Anxiety Inventory(STAI) for measuring anxiety, and Health-related Quality of Questionnaire(HQLQ) for measuring quality of life were administered the 41 non-encephalopathic liver cirrhosis patients(NELC) group and 31 carefully matched normal controls. And a prospective study to compare the performance of NELC group and normal controls on a short but comprehensive cognitive tests was conducted. After several cognitive, NELC group was divided into two groups, SHE group and non-SHE group by results of digit symbol substitution test(DSST) and/or trail making test(TMT) A and B. And then median nerve evoked cortical responses in 13 SHE patients group, 11 non-SHE patients group, and 8 normal controls were recorded for latencies of N13, P16, N20, P25, N30, P45, N65, and P95. And also responses for N13-N20 interpeak latency(IPL) and N20-N65 IPL were recorded. Results : There were significant differences between the NELC group and normal controls on BDI, trait anxiety scales in STAI, and almost all HQLQ except for the cognitive function, social interaction and life satisfaction(p<0.05). The NELC group exhibited poor performance in DSST, TMT A and TMT B compared with normal controls(p<0.05). As 17 NELC patients had abnormal cognitive test results, 41.5% of cirrhotic patients had SHE. In SEP assessment, NELC group with SHE and without SHE had higher N20-N65 IPL and only NELC group with SHE had higher N65 latency compared with normal controls(p<0.05). Conclusion : This study suggests that the patients with liver cirrhosis exhibit relatively selective deficits in complex attentional and fine motor skills, with preservation of general intellectual ability, memory, language and visuospatial perception. DSST, TMT A and TMT B seem to be useful screening tests for the detection of SHE. And also it is expected that late components and N20-N65 IPLs of SEP are helpful in the assessment of SHE.

랫드 위를 지배하는 뇌내 calcitonin gene-related peptide 세포에 관한 면역조직화학적연구

이흥식,이인세,강태천,이봉희 대한해부학회 1997 Anatomy & Cell Biology Vol.30 No.2

사범대학 학생들의 진로상담 네트워크 분석:

신세인(Shin Se in),이준기(Lee Jun Ki) 학습자중심교과교육학회 2015 학습자중심교과교육연구 Vol.15 No.9

사회연결망은 대학생들의 진로 탐색 및 준비 과정에서 결정적인 사회적 자본으로 작용한다. 이 연구의 목적은 대학생들의 진로 상담 네트워크의 구조를 파악하는 것 으로 사범대학 생물교육 전공 학생들의 사례를 중심으로 하였다. 연구 참여자는 사 범대학 생물교육 전공 대학생 53명으로 1학년이 11명, 2학년이 14명, 3학년이 12명, 4학년이 16명이다. 사회네트워크 분석 방법을 통하여 참여 학생들의 진로 상담 네트 워크를 구조적으로 분석하였으며, 학생의 개인적인 특성을 고려하여 네트워크 구조 의 의미를 심층적으로 해석하였다. 연구결과 학생들의 네트워크는 학년과 진로방향 에 따라 나누어진 하위집단으로 구성되었으며 일부 학생들은 하위집단 간 정보 전 달에 중요한 역할을 함이 확인되었다. 또한 교직 외의 다른 진로를 결정한 소수의 학생들은 네트워크에서 고립된 하위집단을 구성하였다. 학생들의 진로 상담 네트워 크 파악은 기존의 수직적 진로지도를 넘어 학생들의 사회적 자본을 고려한 수평적 진로지도를 하는데 구체적 자료를 제시할 수 있다는 점에서 그 의의가 있다. The social network serves as a crucial social capital in the students career exploration and preparation. The purpose of this study is to explore the structure of the college students career counseling network through an example of Teachers College students majoring in Biology Education. Fifty three college students(11 first grade students, 14 second grade students, 12 third grade students, 16 fourth grade students) was participated in this study. Using social network analysis, we analyze students participation in structured career counseling network, consider the personal characteristics of the students through observation and in-depth interviews were interpreting the meaning of the network structure. According to the result, students’career counseling network was comprised of sub-groups divided according to grade some students career direction and it was confirmed that plays an important role in information transfer between sub-groups. In addition, a small number of students determined the teaching career other than isolated sub-groups were configured on the network. Career counseling network is that students understand the significance, in that it can offer concrete data to a horizontal career guidance, taking into account the students social capital beyond the traditional vertical career guidance.