중소기업형 통합일정관리 모듈의 개발

양성민,유대훈,송경동,강주선 경성대학교 생산기술연구소 1996 생산기술연구지 Vol.3 No.-

This research is performed for the purpose of helping small and medium enterprises in Pusan Korea through developing a Total Scheduling Module(TSM) considering their practical environments. The TSM consists of four sub-modules : a basic information sub-modules, a marketing information sub-module, an inventory control sub-module and a production control sub-module. And the TSM is developed for Network version under Client/Server environment.

중소기업 효율성 향상을 위한 품질정보시스템 (Quality Information System) 개발

양광모,전현정,박주식,강경식 明知大學校 産業技術硏究所 2003 産業技術硏究所論文集 Vol.22 No.-

Abstract - The biggest difficulty the small and small business currently face is not to have the effective operation of management system that is the computerization of management, and the problem is the small and medium-sized company can not afford the expenses caused by maintaining and operating such huge man-powers and facilities. Therefore, in this study, we try to develope the Quality Information System allowing the effective outflow and management of information through the availability lf viewing and managing the information by the level by menas of setting the log-in levels for the operation of information, easy revision or medification in the changed structure and new assignment made and followed by the modularization of program. For the accomplishment of above purpose, the material coding work or process allowing the easy classification of materials by emplyees of the company through the in-house standardization of material classifying standard is the foundation for the fast data processing so, it must be achieved first. And also, the purpose of this study is for inducement of the production management and quality control operated by companies to the computerization and automation, and we try to develop the DB Design allowing the realtime monitoring the ordered quantity to quantity to be delivered and output through a unit of PC and the increased consequence with the other works by monitoring the output at the site through the central PC instead of the system monitoring the output at the site by the manager for accomplishment of this purpose.

B2B 환경 제조업의 공급업체에 대한 SCM 구축

양광모,류도희,박주식,강경식 明知大學校 産業技術硏究所 2002 産業技術硏究所論文集 Vol.21 No.-

Today's environment of enterprise is changing. They have to face customers' demands with the right product, the right service and supply them at the right time. And also cut down logistics and inventory cost and bring up the profit as much as they can. This means the change of petting enterprise first in importance to putting customer first in importance. therefore to correspond to customer's demand, shorting lead time is becoming a essential condition. The answer to this changes of environment is supply chain management. In this study, we use Goldratt's drum-buffer-rope scheduling in between manufacturer and supplier. And when shortage of inventory occur, search for the supply chain's CCR. Pressing CCR leer more production, and supply inventory from logistic center to guide for inventory buffing. using logistic warehouse between manufacturer and supplier, can execute function of buffer.

활성화된 마그네슘을 이용한 Michael 반응에 관한 연구

맹주양,김명희,강현구 순천향대학교 기초과학연구소 2000 순천향자연과학연구 논문집 Vol.6 No.1

The Most powerful tools in the synthetic organic chemists arsenal are organometallic compounds and metal mediated transformations. We reported a general approach for highly reactive metal powder by reducing metal salt in tetrahydrofuran solvents using lithium as reducing agents. Organometallic compound was generated by reaction of metal powder with organo compounds and then it was reacted with α ,β -unsaturated ketone. We synthesized 3-(4-chlorophenyl ) -1- (2-thienyl)ethylpropenoate, ethyl- (2-cyano) -3- (thienyl ) -propenoate and ethyl-(2-cyano)-3-(4-chlorophienyl)-propenoate, which are α , β -unsaturated ketone derivations. Magnesium chloride react with Li+Naph-r to give activated magnesium. The synthesized activated magnesium metal reacted with sec-Butylmagnesium chloride and n-Butylmagnesium bromide to give alkyl magnesiumhalide. The active amyl magnesium derivation reacted with the synthesized α , β-unsatruated ketone to give product.

후방불안정성을 동반한 요추 추간판 탈출증에서 Graf 고정술후 발생한 합병증 분석

박주태,신영식,양정호,민강우 영남대학교 의과대학 1998 Yeungnam University Journal of Medicine Vol.15 No.1

본 포항성모병원 정형외과에서는 1991년 5월부터 1995년 12월까지 척추불안정성과 관련된 요추부질환 중 연성고정술을 시행한 145례 중 문제점이 발생된 22례를 분석하여 다음과 같은 결론을 얻었다. 1. 총 145례 중 22례(15.1%)에서 연성고정술로 유발되는 문제점을 발견하였다. 2. 문제점으로 주위분절의 불안정성 증가 10례, 추간판 간격의 감소 8례, 척추경 나사못의 해리 3례, Graf band의 파열이 1례였다. 3. 추간판 간격의 감소 8례 중 초기 질환의 원인으로 추간판이 파열된 경우가 6례로 의의있는 소견을 보였다. 이상과 같은 문제점이 관찰되었으나 주위분절의 불안정성 증가 및 척추경 나사못의 해리는 견고한 고정술에 비해 그 빈도가 낮은 것으로 보이며, 추간판 간격의 감소의 경우 역시 단순 수핵 제거술후 발생된 추간판 간격의 감소보다 빈도가 적었으나, 보다 장기간의 추시 및 계속적인 관찰과 연구가 필요할 것으로 사료된다. The Graf stabilization has been introduced in treating lumbar spinal disorder associated with posterior instability. This study reviewed some problems of the Graf instrumentation as a soft stabilizer. The purpose of this study is to analyse the problems of the soft stabilization in spinal instability. We reviewed 145 cases which were operative treatment using the Graf instrument for lumbar spinal disorder associated with posterior instability at our department from May, 1991 to Dec, 1995. The mean follow up periods was 29 months ranging from 24 months to 6 years 8 months. Of the 145 cases,22 cases were showed the problem. The diagnostic method were simple x-ray, flexion-extension lateral stress view and CT scan. Results were as follows: Adjacent segmental instability was 10 cases(6.9%), disc space narrowing was 8 cases(5.5.%), screw loosening was 3 cases(2.1%) and breakage of the Graf band was 1 case(0.6%). The problems of the soft stabilization were adjacent segmental instability, disc space narrowing, screw loosening, and breakage of the graf band. But the rate of adjacent segmental instability and disc space narrowing was lower than other lumbar spinal instrumentation.

Hippocampal CA 2-3 부위의 Ubiquitin 양성 Neuritic Thread와 대뇌피질 Lewy Body와의 관계

양기화,양기승,강충구,성주호 대한병리학회 1995 Journal of Pathology and Translational Medicine Vol.29 No.5

SCM을 위한 ATP 모델링에 관한 연구

진동주,양광모,박주식,강경식 明知大學校 産業技術硏究所 2002 産業技術硏究所論文集 Vol.21 No.-

최근 기업활동의 자재구매, 제조, 보관 및 운송, 유통/판매까지 포함한 공급체인 전체에 대해 통합관리가 중요한 과제로 부각되고 있다. 현대의 고객들은 제품이나 납기, 품질과 같은 부문에서 높은 서비스를 받고 싶어한다. 이에 따라 오늘 날의 대부분의 기업들은 고도의 기술을 요하는 정보시스템의 도입과, POS, Data Mining 등과 같은 기술들을 이용하고 고객의 요구사항들을 적시, 적소에서 파악하여 고객이 요구하는 상품과 서비스를 공급하기 위하여 최선의 노력을 다하고 있다. 최초의 공급자로부터 소비자까지 상품이 전달되는 과정 중에서 재고와 물류기용은 모든 비용의 대부분을 차지하고 있다. 이에 대한 비용을 줄이려고 하는 것이 공급체인관리(SCM)의 기본적인 목적이라 하겠다. 이에 본 논문에서는 공급체인관리(SCM)에 대한 개념과 배경, 필요성 등을 정리하고 주요 SCM solution에서 제공하는 기능 및 사용된 방법론을 분석하여 이를 바탕으로 주문 접수 시 주문물량의 가능납기를 산정하기 위한 입력데이터, 고려요소, 연산절차 등을 포함한 ATP(Available to Promise) 모델을 제시한다.

Ceftazidime의 임상적 연구 : 과립구 감소환자에서의 감염증에서 Piperacillin-Tobramycin 병합요법과의 비교연구 Ceftazidime or Piperacillin plus Tobramycin and the Possible Modifications Required for a Successful Outcome

최강원,배현주,김양수,김성민,박선양,김병국,김노경,우준희 대한화학요법학회 1990 대한화학요법학회지 Vol.8 No.1

In a randomized, prospective study, ceftazidime monotherapy was compared with a combination of piperacillin and tobramycin for the treatment of infection in febrile granulocyto penic cancer patients. The subjects consisted of 40 patients with acute leukemia or solid tumor who developed fever and other signs of infections after induction chemotherapy or bone marrow transplantation. 21 patients were randomized to the piperacillin plus tobramycin combination, while 19 patients were allocated to ceftazidime monotherapy. Initial granulocyte count, duratation of granulocytopenia, infection days and granulocyte count on therapeutic responsewere all comparable in both treatment groups. On 72 hour assessment, success (with or with-out modification) rate according to NCI criteria was 100% in ceftazidime and 95% in combination group. Success according to EORTC criteria was 26% and 48% respectively. On posttreatment assessment, success rate according to MCI criteria was 91% in ceftazidime group and 70% in combination group, while one according to EORTC was 33% and 40% respectively. There was no statistical significance between the two success rates. The superinfection was more commonly seen in the combination group, esp. by resistant E. coli, even though the difference was not significant.

관해유도 항암요법을 받는 백혈병 환자에서 진균 감염증의 예방 : 무작위 배정법과 이중 눈가림법에 의한 Fluconazole과 Nystain의 효과에 관한 다기관 공동연구 A Randomized, Double-blind, Multicenter Trial to Compare Fluconazole with Nystatin

최강원,오명돈,배현주,백경란,박선양,김병국,신완식,강문원,진종률,박종원,김춘추,김동집,한지숙,민유홍,이선주,고윤웅 대한화학요법학회 1993 대한화학요법학회지 Vol.11 No.2

Fluconazole의 진균 감염증 예방 효과와 안전성에 관하여 3개 대학병원에서 관해유도화학요법을 받는 급성 백혈병환자를 대상으로 무작위 배정법과 너도나도 누가림법에 의하여 연구하였다. 모두 62명의 환자에게 fluconazole(100㎎ bid) 또는 nystatin(1,000,000IU/day)을 무작위로 투여하였다. 투약은 관해유도화학요법과 같은 날짜에 시작하여 호중구수가 1,000㎣이상으로 회복되거나 진균 감염증이 확인되거나 의심되어 Amphotericin-B를 시작하거나, 약과 관련된 부작용이 나타날 때까지 계속하였다. 진균 colonization은 fluconazole군에서 감소하였으나 nystqatin군에서는 증가하였다, 표재성 진균감염증으로 nystatin군에서 C. albicans 진균혈증 1례와 C.parasilosis 진균혈중 1례가 발생하였다. 경험적 항진균요법으로 Amphotericin-B를 투여한 경우는 fluconazolerns 34명중 7례(21%), nystatinrns 28명중 10례(36%)였다(p<0.05). Fluconazole군과 nystatin군 사이에 부작용이나 사망률에 차이는 없었다. 결론적으로, fluconazole은 관해유도화학요법을 받는 급성 백혈병환자에서 진균의 colonization을 줄이는데 효과적이고 안전한 항진균제이다. We made a randomized, double-blind, multicenter trial to compare the efficacy and safety of fluconazole with nystatin for prevention of fungal infections in patients with acute leukemia. Sixty-two adult undergoing remission induction chemotherapy for cute leukemia were enrolled. Patients were randomly assigned to receive either fluconazole (100㎎ bid) or nystatin(1,000,000IU×6/day) with corresponding placebo. The study drug was started in initiation of chemotherapy and continued until recovery of neutrophil counts(>1,000/㎣), development of proven or suspected invasive fungal infection, or the occurrence of drug-related toxicity. Fungal colonization decreased in fluconazole(F) group, however increased in nystain(n) group. Superficial fungal infection occurred in 1 of 34 F group, whereas invasive fungal infection developed in 3 of 28 N group. Empirical amphotericin-B therapy was given in 7 of 34(21%) F group and 10 of 28(36%) N group(p>0.05). The incidence of drug-related side effects and overall moratlity were similar in both study groups.

형광백혈구 안저촬영술에서 플로레신 염색의 안정성과 형광림프구의 분리

김윤희,강필성,김강주,양연식,김재덕 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.1

Recently, retinal blood flow has been studied with several methods, targeted dye delivery method, fluorescent vesicle system, laser Doppler velocimetry, acridine orange staining method. Authors presented a new method, fluorescein leukocyte angiography using a scanning laser ophthalmoscope which include external staining of leukocyte with fluorescein dye and reintroduce the fluorescent leukocyte into the blood flow. Authors tried to check security of external fluorescein staining of leukocytes and separation of fluorescent lymphocytes from whole blood and supernatant fluid using Ficoll-Paque, with cell viability, leukocyte recovery rate and erythrocyte contamination rate. There was no significant difference in cell viability, leukocyte recovery rate and erythrocyte contamination rate between fluorescein staining group and non-staining group. Fluorescent lymphocytes could be separated from whole blood and supernatant solution after gravity sedimentation with 6% hetastarch and the gravity sedimented group had low erythrocyte contamination rate than whole blood group(p≤0.05). In conclusion, external fluorescein staining procedure of leukocyte during fluorescein leukocyte angiography could be performed without cell injury compared to non-fluorescein staining group and fluorescent lymphocyte could be separated from whole blood and supernatant fluid after gravity sedimentation.