http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Chen, P.,Tian, Q.,Baek, S.J.,Shang, X.L.,Park, A.,Liu, Z.C.,Yao, X.Q.,Wang, J.Z.,Wang, X.H.,Cheng, Y.,Peng, J.,Shen, A.G.,Hu, J.M. WILEY‐VCH Verlag 2011 Laser physics letters Vol.8 No.7
<P><B>Abstract</B></P><P>Early and differential diagnosis of Alzheimer's disease (AD) is a problem that puzzled many doctors. Reliable markers in easy‐assembling samples are of considerable clinical diagnostic value. In this work, laser Raman spectroscopy (LRS) was developed a new method that potentially allows early and differential diagnosis of AD from the platelet sample. Raman spectra of platelets isolated from different ages of AD transgenic mice and non‐transgenic controls were collected and analyzed. Multilayer perceptron networks (MLP) classification method was used to classify spectra and establish the diagnostic models. For differential diagnosis, spectra of platelets isolated from AD, Parkinson’s disease (PD) and vascular dementia (VD) mice were also discriminated. Two notable spectral differences at 740 and 1654 cm<SUP>–1</SUP> were revealed in the mean spectrum of platelets isolated from AD transgenic mice and the controls. MLP displayed a powerful ability in the classifying of early, advanced AD and the control group, and in differential diagnosis of PD and advanced AD, as well as VD and advanced AD. The results suggest that platelet detecting by LRS coupled with MLP analysis appears to be an easy and accurate method for early and differential diagnosis of AD. This technique could be rapidly promoted from laboratory to the hospital. (© 2011 by Astro Ltd., Published exclusively by WILEY‐VCH Verlag GmbH & Co. KGaA) (© 2011 by Astro Ltd., Published exclusively by WILEY‐VCH Verlag GmbH & Co. KGaA)</P>
Fabrication of Nitrogen Doped p-ZnO and ZnO Light-Emitting Diodes on Sapphire
Y. M. Lu,Z. P. Wei,D. Z. Shen,Z. Z. Zhang,B. Yao,B. H. Li,J. Y. Zhang,D. X. Zhao,X. W. Fan,Z. K. Tang 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.5
Nitrogen-doped p-type ZnO thin films were grown on c-plane sapphire (Al2O3) substrates by plasma-assistant molecular beam epitaxy, where O2 and N2 were introduced via a RF plasma source simultaneously. In situ optical emission spectra of the plasma were employed to monitor the chemical species in the active gas sources, one of the most important growth parameters. By adjusting the growth parameters, we confirm the optimal condition for p-type doping growth. The reproducible p-type ZnO thin films have the hole concentration (NA −ND) up to 1.0 × 1018 cm−3 and the resistivity of 6 cm. A ZnO LED was fabricated by depositing undoped n-type ZnO on the p-type layer. Electroluminescence spectra centered about 430 nm were obtained even at 350 K.
Ling, Y.H.,Zhang, X.D.,Yao, N.,Ding, J.P.,Chen, H.Q.,Zhang, Z.J.,Zhang, Y.H.,Ren, C.H.,Ma, Y.H.,Zhang, X.R. Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.2
To investigate the genetic diversity of seven Chinese indigenous meat goat breeds (Tibet goat, Guizhou white goat, Shannan white goat, Yichang white goat, Matou goat, Changjiangsanjiaozhou white goat and Anhui white goat), explain their genetic relationship and assess their integrity and degree of admixture, 302 individuals from these breeds and 42 Boer goats introduced from Africa as reference samples were genotyped for 11 microsatellite markers. Results indicated that the genetic diversity of Chinese indigenous meat goats was rich. The mean heterozygosity and the mean allelic richness (AR) for the 8 goat breeds varied from 0.697 to 0.738 and 6.21 to 7.35, respectively. Structure analysis showed that Tibet goat breed was genetically distinct and was the first to separate and the other Chinese goats were then divided into two sub-clusters: Shannan white goat and Yichang white goat in one cluster; and Guizhou white goat, Matou goat, Changjiangsanjiaozhou white goat and Anhui white goat in the other cluster. This grouping pattern was further supported by clustering analysis and Principal component analysis. These results may provide a scientific basis for the characteristization, conservation and utilization of Chinese meat goats.
Feng, Y.,Yang, X.J.,Wang, Y.B.,Li, W.L.,Liu, Y.,Yin, R.Q.,Yao, J.H. Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.5
Immune stress is the loss of immune homeostasis caused by external forces. The purpose of this experiment was to investigate the effects of immune stress on the growth performance, small intestinal enzymes and peristalsis rate, and mRNA expression of nutrient transporters in broiler chickens. Four hundred and thirty-two 1-d-old broilers (Cobb500) were randomly assigned to four groups for treatment; each group included nine cages with 12 birds per cage. Group 1 = no vaccine (NV); Group 2 = conventional vaccine (CV); group 3 = lipopolysaccharide (LPS)+conventional vaccine (LPS); group 4 = cyclophosphamide (CYP)+conventional vaccine (CYP). The results demonstrated that immune stress by LPS and CYP reduced body weight gain (BWG), feed intake (FI), small intestine peristalsis rate and sIgA content in small intestinal digesta (p<0.05). However, the feed conversion ratio (FCR) remained unchanged during the feeding period. LPS and CYP increased intestinal enzyme activity, relative expression of SGLT-1, CaBP-D28k and L-FABP mRNAs (p<0.05). LPS and CYP injection had a negative effect on the growth performance of healthy broiler chickens. The present study demonstrated that NV and CV could improve growth performance while enzyme activity in small intestine and relative expression of nutrient transporter mRNA of NV and CV were decreased in the conditions of a controlled rational feeding environment. It is generally recommended that broilers only need to be vaccinated for the diseases to which they might be exposed.
Fabrication of p-Type Nitrogen-Doped MgZnO by Depressing N-Related Donors
B. Yao,Z. P. Wei,Y. F. Li,D. Z. Shen,Y. M. Lu,Z. Z. Zhang,B. H. Li,C. J. Zheng,X. H. Wang,J. Y. Zhang,D. X. Zhao,X. W. Fan,Z. K. Tang 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.5
Wurtzite nitrogen-doped MgZnO (MgZnO:N) films were grown on c-plane sapphire by using plasma-assisted molecular beam epitaxy with radical NO as the oxygen source and nitrogen dopant. P-type conduction of MgZnO:N was obtained by decreasing the donor defects ((N2)O, VO, etc.) through annealing, revealing a hole concentration of 6.1 × 1017 cm−3 and a mobility of 6.42 cm2/Vs. Furthermore, as-grown p-type films with a hole concentration of 1 × 1017 cm−3 and a mobility of 3 cm2/Vs were obtained by decreasing the (N2)O double donor defect through control of the plasma conditions. ZnMgO:N/ZnO p-n junctions were obtained by using these p-type films. ode-like, rectifying I-V characteristics with a threshold voltage of about 5 V and a different reverse leakage current were observed at room temperature.
Development of the 3.7 GHz LHCD System on HL-2A
B. Lu,M. Huang,H. Zeng,X. Y. Bai,X. H. Mao,Z. H. Lu,J. Liang,Z. H. Kang,M. W. Wang,K. Feng,H. Wang,C. Wang,J. Q. Wang,S. Wei,T. Yao,Y. N. Bu,J. Feng,G. Y. Cheng,S. D. Song,D. H. Xia,J. Rao 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.8
A 2 MW-3.7 GHz lower hybrid current drive (LHCD) system is under development for physicsexperiments on the HL-2A device. The RF Power is generated by four TH2103A klystron amplifiersand propagates in the TE10 mode through WR284 waveguides. The transmission lines with a lengthof 20 m to 30 m are pressurized with 2 bars of nitrogen to decrease the possibility of arcing. Thelauncher, based on the passive-active multi-junction (PAM) concept, has been developed and iscurrently being realized. It was designed for a power spectrum peaked at Nk = 2.75 with goodcoupling properties over a wide range of plasma parameters. The four klystrons are fed by ahigh-voltage power supply (HVPS) based on the pulse step modulation (PSM) concept with a fastswitch-off time of less than ten μs. This system is expected to be in operation within 1 years and willexplore many international thermonuclear experimental reactor (ITER) related LH experiments inthe following years.
Zhang, X.,Shi, L.,Li, X.,Sheng, Q.,Yao, L.,Shen, D.,Lu, Z.R.,Zhou, H.M.,Park, Y.D.,Lee, J.,Zhang, Q. Society for Bioscience and Bioengineering, Japan ; 2014 Journal of bioscience and bioengineering Vol.117 No.6
Understanding the mechanism of inhibition of α-glucosidase (EC 3.2.1.20) is clinically important because of the involvement of this enzyme in type 2 diabetes mellitus. In this study, we conducted inhibition kinetics of α-glucosidase with Ca<SUP>2+</SUP> and 10-ns molecular dynamics simulations. We found that direct binding of Ca<SUP>2+</SUP> to the enzyme induced structural changes and inhibited enzyme activity. Ca<SUP>2+</SUP> inhibited α-glucosidase in a mixed-type reaction (K<SUB>i</SUB> = 27.0 +/- 2.0 mM) and directly induced the unfolding of α-glucosidase, which resulted in the exposure of hydrophobic residues. The simulations suggest that thirteen Ca<SUP>2+</SUP> ions may interact with α-glucosidase residues and that the Ca<SUP>2+</SUP> binding sites are associated with the structural changes in α-glucosidase. Our study provides insight into the mechanism of the Ca<SUP>2+</SUP>-induced structural changes in α-glucosidase and the inhibition of ligand binding. These results suggest that Ca<SUP>2+</SUP> could act as a potent inhibitor of α-glucosidase for the treatment of type 2 diabetes mellitus.