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      • KCI등재

        Experimental Study of the Runaway Current in the J-TEXT Tokamak

        Y. H. Luo,Z. Y. Chen,X. Q. Zhang,D. W. Huang,W. Jin,Y. H. Huang,Y. Tang,J. C. Li,R. H. Tong,W. Yan,G. Zhuang 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.64 No.3

        Major plasma disruptions in tokamaks often generate runaway currents, which contain electronswith energies of several tens of megaelectron-volts (MeV). These currents can cause substantialdamage when control is lost and the current hits the limiters or the vessel wall. The interactionbetween the runaway electrons and the impurities inside the plasma results in soft X-ray emission,which can provide detailed information about the runaway generation process and the confinementof runaway electrons. A vertical soft X-ray array at the top of Joint Texas Experimental Tokamak(J-TEXT) was used to study the runaway beams resulting from major disruptions. Runawayelectron production and confinement of runaway current were observed by using soft X-ray images.

      • Logarithmically completely monotonic functions and Gurland's ratio for the gamma function

        Y. J. Wei,S. L. Zhang,C. P. Chen 장전수학회 2007 Advanced Studies in Contemporary Mathematics Vol.15 No.2

        Two logarithmically completely monotonic functions involving gamma function are proved. As an application, bounds for the ratio T(x;y) = ( x)(y)= 2((x+y)=2) is established and the corresponding result by J. D. keckic and P. M.Vasic is refined.

      • SCISCIESCOPUS

        Tailoring the defects and carrier density for beyond 10% efficient CZTSe thin film solar cells

        Li, J.,Kim, S.,Nam, D.,Liu, X.,Kim, J.,Cheong, H.,Liu, W.,Li, H.,Sun, Y.,Zhang, Y. North-Holland ; Elsevier Science Ltd 2017 Solar energy materials and solar cells Vol.159 No.-

        The defects states and carrier density of CZTSe absorber layers are two of the crucial factors that decide the photovoltaic performance of CZTSe thin film solar cells. Fine tailoring the defects and carrier density is a key to push the power conversion efficiency of CZTSe solar cells to a more competitive level. In this work, the phase properties, defect states, and carrier density of CZTSe thin film are well controlled by fine tuning the ratio of Zn/Sn in the range from 0.75 to 1.27. Capacity-Voltage measurements and Admittance Spectroscopy are used to characterize the carrier density, depletion region width, and defect states of the CZTSe solar cells. The results indicate that the defects states and carrier density of CZTSe layer are very sensitive to the ratio of Zn/Sn. Combining experimental results and numerical simulation, the statistic regularities of the photovoltaic parameters of the CZTSe solar cells with different ratios of Zn/Sn is well explained. The increase of V<SUB>OC</SUB> of CZTSe solar cells with the ratio of Zn/Sn is related to both the increased carrier density and the decreased deep level defects states. The decline of J<SUB>SC</SUB> of the Zn-rich solar cells is caused by both the shrunken depletion region width and a large barrier caused by ZnSe phase. This barrier is the cause for a low fill factor in the Zn-rich solar cells. Overall, the CZTSe solar cells with a stoichiometric ratio of Zn/Sn=1.02 have favorable defects property and carrier density, thus resulting in the highest photovoltaic efficiency of 10.21%.

      • The ameliorating effect of 1-palmitoyl-2-linoleoyl-3-acetylglycerol on scopolamine-induced memory impairment via acetylcholinesterase inhibition and LTP activation

        Jeon, S.J.,Kim, B.,Park, H.J.,Zhang, J.,Kwon, Y.,Kim, D.H.,Ryu, J.H. Elsevier/North-Holland Biomedical Press 2017 Behavioural brain research Vol.324 No.-

        In the present study, we investigated whether 1-palmitoyl-2-linoleoyl-3-acetylglycerol (PLAG), a component of antlers of Cervus nippon Temminck, would have memory-ameliorating properties against cholinergic blockade-induced memory impairment in mice. In the passive avoidance task to investigate the effects of PLAG on long-term memory, PLAG (10mg/kg, p.o.) administration ameliorated scopolamine-induced memory impairment. PLAG also reversed the impairments of working memory in the Y-maze task and spatial memory as shown in the Morris water maze. To identify the mechanism of the memory-ameliorating effect of PLAG, acetylcholinesterase (AChE) inhibition assay and the Western blot analysis were conducted. In the AChE inhibition assay, PLAG inhibited the AChE activity in mice and PLAG increased the expression levels of phosphorylated CaMKII, ERK, and CREB in the hippocampus. Additionally, long-term potentiation (LTP) of synaptic strength occurred by PLAG treatment in the hippocampal cultures. Overall, the present study suggests that PLAG reversed memory deficits in an animal model and that it affects biochemical pathways related to learning and memory.

      • KCI등재

        Ultimate strength behavior of steel-concrete-steel sandwich beams with ultra-lightweight cement composite, Part 2: Finite element analysis

        Jia-Bao Yan,J.Y. Richard Liew,Min-Hong Zhang 국제구조공학회 2015 Steel and Composite Structures, An International J Vol.18 No.4

        Ultra-lightweight cement composite (ULCC) with a compressive strength of 60 MPa and density of 1,450 kg/㎥ has been developed and used in the steel-concrete-steel (SCS) sandwich structures. This paper investigates the structural performances of SCS sandwich composite beams with ULCC as filled material. Overlapped headed shear studs were used to provide shear and tensile bond between the face plate and the lightweight core. Three-dimensional nonlinear finite element (FE) model was developed for the ultimate strength analysis of such SCS sandwich composite beams. The accuracy of the FE analysis was established by comparing the predicted results with the quasi-static tests on the SCS sandwich beams. The FE model was also applied to the nonlinear analysis on curved SCS sandwich beam and shells and the SCS sandwich beams with J-hook connectors and different concrete core including ULCC, lightweight concrete (LWC) and normal weight concrete (NWC). Validations were also carried out to check the accuracy of the FE analysis on the SCS sandwich beams with J-hook connectors and curved SCS sandwich structure. Finally, recommended FE analysis procedures were given.

      • A Phase 3 Evaluation of Daclatasvir plus Asunaprevir in Treatment-Naive Patients with Chronic HCV Genotype 1b Infection

        ( L. Wei ),( F. Wang ),( M. Zhang ),( J. Jia ),( A.A. Yakovlev ),( W. Xie ),( E.Z. Burnevich ),( J. Niu ),( Y.J. Jung ),( X. Jiang ),( M. Xu ),( X. Chen ),( Q. Xie ),( J. Li ),( J. Hou ),( H. Tang ),( 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

        Background/Aims: Treatment-naive GT 1b-infected patients from mainland China, South Korea and Russia were assessed for SVR at follow-up week 12 (SVR12) after receiving daclatasvir (60 mg, QD) and asunaprevir (100 mg, BID) (DCV+ASV). Methods: Patients were randomized 3:1 to receive DCV+ASV (24 weeks; immediate treatment [IM]) or 12 weeks of placebo followed by DCV+ASV (24 weeks; placebo-deferred treatment [PD]). The primary endpoint was to evaluate SVR12 in the IM arm to the historical rate for peginterferon/ribavirin (70%). Secondary endpoints included overall safety and safety comparisons between the treatment arms during the first 12 weeks. Results: 207 patients were randomized to IM (n=155) or PD (n=52); Asian (86%), female (59%), IL28B CC genotype (68%) and median age 49 (range 18-73) years; cirrhosis (13%), HCV RNA ≥6x106 IU/mL (53%). SVR12 in the IM arm was 92% and broadly unaffected by most baseline factors assessed (Figure); SVR12 was higher in patients without (96%) baseline NS5A-L31M/V or Y93H polymorphisms. There were 6 virologic breakthroughs, 6 relapses and 1 detectable HCV RNA at end-of-treatment in the IM arm. Safety was mostly comparable between the two arms during the first 12 weeks. The most frequent adverse events (AEs; ≥5%) during DCV+ASV (24 weeks) treatment in both arms were aminotransferase, bilirubin and INR elevations, hypertension, fatigue and respiratory tract infections; the most frequent treatment-emergent grade 3/4 laboratory abnormalities were aminotransferase (≤4.5%) and hematologic, lipase and total bilirubin abnormalities (≤2%); one patient (IM) discontinued DCV+ASV for aminotransferase elevations, nausea and jaundice (all reversible); one patient PD) discontinued DCV+ASV for a fatal AE unrelated to treatment. Conclusions: These data demonstrate that DCV+ASV is a highly efficacious and well tolerated treatment for treatment-naive HCV GT 1b-infected patients. Those treated immediately with DCV+ASV achieved a 92% SVR12 rate which was unaffected by factors known to attenuate response to interferon.

      • SCISCIESCOPUS

        THE TAIWANESE-AMERICAN OCCULTATION SURVEY PROJECT STELLAR VARIABILITY. II. DETECTION OF 15 VARIABLE STARS

        Mondal, S.,Lin, C. C.,Chen, W. P.,Zhang, Z.-W.,Alcock, C.,Axelrod, T.,Bianco, F. B.,Byun, Y.-I.,Coehlo, N. K.,Cook, K. H.,Dave, R.,Kim, D.-W.,King, S.-K.,Lee, T.,Lehner, M. J.,Lin, H.-C.,Marshall, S. American Institute of Physics 2010 The Astronomical journal Vol.139 No.5

        <P>The Taiwanese-American Occultation Survey (TAOS) project has collected more than a billion photometric measurements since 2005 January. These sky survey data—covering timescales from a fraction of a second to a few hundred days—are a useful source to study stellar variability. A total of 167 star fields, mostly along the ecliptic plane, have been selected for photometric monitoring with the TAOS telescopes. This paper presents our initial analysis of a search for periodic variable stars from the time-series TAOS data on one particular TAOS field, No. 151 (R.A. = 17<SUP>h</SUP>30<SUP>m</SUP>6<img entity='fs' SRC='http://ej.iop.org/icons/Entities/fs.gif' ALT='fs' ALIGN='BASELINE' />7, decl. = 27°17'30'', J2000), which had been observed over 47 epochs in 2005. A total of 81 candidate variables are identified in the 3 deg<SUP>2</SUP> field, with magnitudes in the range 8 < R < 16. On the basis of the periodicity and shape of the light curves, 29 variables, 15 of which were previously unknown, are classified as RR Lyrae, Cepheid, δ Scuti, SX Phonencis, semi-regular, and eclipsing binaries.</P>

      • KCI등재

        R&D Status of High-current Accelerators at IFP

        J. J. Deng,J. S. Shi,W. P. Xie,L. W. Zhang,K. Z. Zhang,S. P. Feng,J. Li,M. Wang,Y. He,L. S. Xia,Z. Y. Dai,H. T. Li,L. Wen,S. F. Chen,X. Li,Q. G. Lai,M. H. Xia,Y. C. Guan,S. Y. Song,L. Chen 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.61

        High-current accelerators have many important applications in Z-pinches, high-power microwaves, and free electron lasers, imploding liners and radiography and so on. Research activities on Zpinches, imploding liners, radiography at the Institute of Fluid Physics (IFP) are introduced. Several main high-current accelerators developed and being developed at IFP are described, such as the Linear Induction Accelerator X-Ray Facility Upgrade (LIAXFU, 12 MeV, 2.5 kA, 90 ns), the Dragon-I linear induction accelerator (20 MeV, 2.5 kA, 60 ns), and the Primary Test Stand for Z-pinch (PTS, 10 MA, 120 ns). The design of Dragon-II linear induction accelerator (20 MeV, 2.5 kA, 3 × 60 ns) to be built will be presented briefly.

      • Inhibitory effect of fenofibrate on neointima hyperplasia via G<sub>0</sub>/G<sub>1</sub> arrest of cell proliferation

        Lee, J.J.,Yu, J.Y.,Zhang, W.Y.,Kim, T.J.,Lim, Y.,Kwon, J.S.,Kim, D.W.,Myung, C.S.,Yun, Y.P. North-Holland ; Elsevier Science Ltd 2011 european journal of pharmacology Vol.650 No.1

        We have previously reported that fenofibrate displayed a potent antithrombotic effect by the inhibition of platelet aggregation. The present study was designed to investigate the effects of fenofibrate on the neointimal hyperplasia and its possible molecular mechanism. Neointimal hyperplasia was measured in balloon-inflated-induced vascular injury model of male Sprague-Dawley rats and cell proliferation was measured in primary cultured rat aortic vascular smooth muscle cells (VSMCs). Fenofibrate-treated group showed a significant reduction in neointimal formation (0.07+/-0.04mm<SUP>2</SUP>) from the control (0.13+/-0.04mm<SUP>2</SUP>). Fenofibrate significantly inhibited platelet-derived growth factor (PDGF)-BB-induced cell counting and [<SUP>3</SUP>H]-thymidine incorporation into DNA. Fenofibrate suppressed the PDGF-BB-inducible progression through G<SUB>0</SUB>/G<SUB>1</SUB> to S phase of cell cycle. Moreover, fenofibrate inhibited not only phosphorylation of retinoblastoma (Rb) protein and expression of cyclin D/E, CDK 2/4 and proliferating cell nuclear antigen (PCNA) proteins but also mitogen-activated protein kinase (MAPK) signaling pathways such as ERK ½, p38 and JNK phosphorylation. In conclusion, the present study demonstrates that fenofibrate significantly inhibits neointimal formation via G<SUB>0</SUB>/G<SUB>1</SUB> arrest of PDGF-BB-induced cell proliferation in association with the inhibition of MAPK, which resulted in the downregulation of expressions of cyclin D/E, CDK 2/4 and PCNA proteins, suggesting that fenofibrate may be useful for individuals with a high risk of thrombotic or cardiovascular diseases.

      • SCIESCOPUSKCI등재

        Dietary Requirement of True Digestible Phosphorus and Total Calcium for Growing Pigs

        Ruan, Z.,Zhang, Y.-G.,Yin, Y.-L.,Li, T.-J.,Huang, R.-L.,Kim, S.W.,Wu, G.Y.,Deng, Z.Y. Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.8

        Sixty healthy growing pigs ($Duroc{\times}Landrace{\times}Yorkshire$ with an average BW of 21.4 kg) were used to determine the true digestible phosphorus (TDP) requirement of growing pigs on the basis of growth performance and serum biochemical indices. Pigs were assigned randomly to one of five dietary treatments (12 pigs/diet), representing five levels of TDP (0.16%, 0.20%, 0.23%, 0.26% and 0.39%). There were three replications per treatment, with four pigs (2 barrows and 2 gilts) in each replication (2 pigs/pen) A randomized-block design was used, with pen as the experimental unit. Experimental diets were formulated to provide the 5 TDP levels with a total calcium (Ca) to TDP ratio of 2:1, and offered to pigs at 5% BW for 28 d. The total Ca contents of the five diets were 0.33, 0.38, 0.45, 0.51 and 0.79%, respectively. During the 28-d experimental period, the ADG of pigs was affected by dietary TDP levels as described by Equation 1: y = $-809,532x^4+788,079x^3-276,250x^2+42,114x-1$,759; ($R^2$ = 0.99; p<0.01; y = ADG, g/d; x = dietary TDP, %). The feed:gain ratio for pigs was affected by dietary TDP levels as described by Equation 2: y = $3,651.1x^4-3,480.4x^3+1,183.8x^2-172.5x+10.9$ ($R^2$ = 0.99; p<0.01; y = feed:gain ratio; x = dietary TDP, %). Total P concentrations in serum were affected by dietary TDP levels as described by Equation 3: y = $-3,311.7x^4+3,342.7x^3-1,224.6x^2+195.6x-8.7$ ($R^2$ = 0.99; p<0.01; y = total serum P concentration and x = dietary TDP, %). The highest ADG (782 g/d), the lowest feed:gain ratio (1.07), and the highest total serum P concentration (3.1 mmol/L) were obtained when dietary TDP level was 0.34%. Collectively, these results indicate that the optimal TDP requirement of growing pigs is 0.34% of the diet (e.g., 5.1 g/day for a 30-kg pig that consumed 1.5 kg feed daily) at a total Ca to TDP ratio of 2:1.

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