Reliability Evaluation Technique for Electrical Distribution Networks Considering Planned Outages

Bo Hu,Xiao-Hui He,Kan Cao 대한전기학회 2014 Journal of Electrical Engineering & Technology Vol.9 No.5

The reliability evaluation of the electrical distribution networks (EDN) requires sufficient consideration of the effects of planned outages. The planned outages of the EDN can be divided, by outage models and their effects on the reliability into two major categories: by equipment and by feeder. After studying the characteristics of different categories of planned outages, this paper expands the classification of load points by outage time from 4 types to 7 types and defines corresponding reliability parameters for the different types. By using the section algorithm, this paper proposes a reliability evaluation technique of EDN considering equipment random failures and two categories of planned outages. The proposed technique has been applied to the RBTS-BUS6 test system and some practical EDNs in China. The study results demonstrate that the proposed technique is of higher practical value and can be used for evaluating the reliability performance of EDN more efficiently considering the planned outages.

Study of the Correlation of Plasma Resonance and the Refractive Index to Dielectric Dispersion in the Complex Plane

Xiao-Yong Zhou,Yan Shen,Er-Tao Hu,Jian-Bo Chen,Yuan Zhao,Ming-Yu Sheng,Jing Li,Yu-Xiang Zheng,Hai-Bin Zhao,Liang-Yao Chen,Wei Li,Xun-Ya Jiang,이영백,David W. Lynch 한국광학회 2013 Current Optics and Photonics Vol.17 No.1

Based on the dispersive feature of the dielectric function of noble metals and the wave vector conservation in physics, both the plasma effect and the complex refractive index, which are profoundly correlated to the complex dielectric function and permeability, have been studied and analyzed. The condition to induce a bulk or a surface plasma in the visible region will not be satisfied, and there will be one solution for the real and the imaginary parts of the refractive index, restricting it only to region I of the complex plane. The results given in this work will aid in understanding the properties of light transmission at the metal/dielectric interface as characterized by the law of refraction in nature.

Characterizations of Ru/ZnO catalysts with different Ru contents for selective hydrogenation of crotonaldehyde

Bo Li,Meng-Fei Luo,Geng-Shen Hu,Ling-Yun Jin,Xiao Hong,Ji-Qing Lu 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.1

Ru catalysts supported on ZnO with different Ru contents were prepared by an impregnation method and were applied to the vapor-phase selective hydrogenation of crotonaldehyde. The catalysts were characterized by X-ray powder diffraction (XRD), NH3 temperature-programmed desorption (NH3-TPD),transmission electron microscopy (TEM) and temperature-programmed oxidation (TPO). It was found that with increasing Ru contents in the Ru/ZnO catalysts, the activity (TOF), surface acidity amount and deactivation rate increased and the selectivity to crotyl alcohol increased first and then decreased. The 3Ru/ZnO catalyst showed the highest selectivity to crotyl alcohol (up to 88.0%) for the hydrogenation of crotonaldehyde. The initial TOF values of the catalysts depended on the strength of surface acidity and the Ru particle sizes. The more Lewis acid sites made catalysts deactivate more easily. It was assumed that the deactivation was due to the formation of organic compounds deposition and poison effect of CO strongly adsorbed on the Ru atoms.

Augmenter of Liver Regeneration Alleviates Renal Hypoxia-Reoxygenation Injury by Regulating Mitochondrial Dynamics in Renal Tubular Epithelial Cells

Xiao-hui Liao,Rui-ting Long,Jun-bo Peng,Li-li Huang,Gui-ping Jiang,Yue-juan Liao,Hang Sun,Yu-dong Hu 한국분자세포생물학회 2019 Molecules and cells Vol.42 No.12

Mitochondria are highly dynamic organelles that constantly undergo fission and fusion processes that closely related to their function. Disruption of mitochondrial dynamics has been demonstrated in acute kidney injury (AKI), which could eventually result in cell injury and death. Previously, we reported that augmenter of liver regeneration (ALR) alleviates renal tubular epithelial cell injury. Here, we gained further insights into whether the renoprotective roles of ALR are associated with mitochondrial dynamics. Changes in mitochondrial dynamics were examined in experimental models of renal ischemia-reperfusion (IR). In a model of hypoxia-reoxygenation (HR) injury in vitro, dynamin-related protein 1 (Drp1) and mitochondrial fission process protein 1 (MTFP1), two key proteins of mitochondrial fission, were downregulated in the Lv-ALR + HR group. ALR overexpression additionally had an impact on phosphorylation of Drp1 Ser637 during AKI. The inner membrane fusion protein, Optic Atrophy 1 (OPA1), was significantly increased whereas levels of outer membrane fusion proteins Mitofusin-1 and -2 (Mfn1, Mfn2) were not affected in the Lv-ALR + HR group, compared with the control group. Furthermore, the mTOR/4E-BP1 signaling pathway was highly activated in the Lv-ALR + HR group. ALR overexpression led to suppression of HR-induced apoptosis. Our collective findings indicate that ALR gene transfection alleviates mitochondrial injury, possibly through inhibiting fission and promoting fusion of the mitochondrial inner membrane, both of which contribute to reduction of HK-2 cell apoptosis. Additionally, fission processes are potentially mediated by promoting tubular cell survival through activating the mTOR/4E-BP1 signaling pathway.

Reliability Evaluation Technique for Electrical Distribution Networks Considering Planned Outages

Hu, Bo,He, Xiao-Hui,Cao, Kan The Korean Institute of Electrical Engineers 2014 Journal of Electrical Engineering & Technology Vol.9 No.5

The reliability evaluation of the electrical distribution networks (EDN) requires sufficient consideration of the effects of planned outages. The planned outages of the EDN can be divided, by outage models and their effects on the reliability into two major categories: by equipment and by feeder. After studying the characteristics of different categories of planned outages, this paper expands the classification of load points by outage time from 4 types to 7 types and defines corresponding reliability parameters for the different types. By using the section algorithm, this paper proposes a reliability evaluation technique of EDN considering equipment random failures and two categories of planned outages. The proposed technique has been applied to the RBTS-BUS6 test system and some practical EDNs in China. The study results demonstrate that the proposed technique is of higher practical value and can be used for evaluating the reliability performance of EDN more efficiently considering the planned outages.

High expression of keratin 6C is associated with poor prognosis and accelerates cancer proliferation and migration by modulating epithelial–mesenchymal transition in lung adenocarcinoma

Hai‑Bo Hu,Xiao‑Ping Yang,Pei‑Xia Zhou,Xin‑Ai Yang,Bin Yin 한국유전학회 2020 Genes & Genomics Vol.42 No.2

Background Lung adenocarcinoma (LUAD) is a more frequent subtype of lung cancer and most cases are discovered in the late stages. The proliferation and metastasis of LUAD are pivotal for disease progression. Despite unremitting deeper understanding of LUAD biology, the mechanisms involved in the proliferation and metastasis of LUAD remain unclear. The objective of our article was to inquiry the expression and the function of keratin 6C (KRT6C) in LUAD cells. Methods First, the expression level and prognostic value of KRT6C in LUAD tissues were analyzed on the basis of the data acquired from TCGA database. Through qRT-PCR, the expression level of KRT6C on LUAD cell lines (A549, H1299, PC-9) and human normal lung cell line MRC-5 was tested. After that, CCK8 and colony formation assays was utilized to detect cell proliferation. In addition, to explore the influence of KRT6C on LUAD migration and invasion ability, scratch wound healing and transwell assays were utilized. Through western blotting, the protein expression levels of KRT6C, PCNA, E-cadherin, N-cadherin, Snail and Vimentin were detected. Results The outcomes revealed that KRT6C was highly expressed in LUAD tissues and cell lines. Besides, elevated level of KRT6C was related to worse prognosis in LUAD patients. Ablation of KRT6C restrained proliferation, migration and invasion of A549 cells. KRT6C deficiency augmented the expression of E-cadherin as well as reduced the expression of N-cadherin, Snail and Vimentin. Conclusion Above all, these consequences indicated that depletion of KRT6C suppressed A549 cell proliferation, migration and invasion, which might be achieved by regulating EMT. In general, KRT6C is identified as a potential therapeutic target for LUAD.

Development of a Method Based on Surface Enhanced Laser Desorption and Ionization Time of Flight Mass Spectrometry for Rapid Identification of Klebsiella pneumoniae

Daiwen Xiao,Yongchang Yang,Hua Liu,Hua Yu,Yingjun Yan,Wenfang Huang,Wei Jiang,Weijin Liao,Qi Hu,Bo Huang 한국미생물학회 2009 The journal of microbiology Vol.47 No.5

A method based on surface enhanced laser desorption and ionization time of flight mass spectrometry (SELDI-TOF MS) was developed for the rapid identification of Klebsiella pneumoniae by directly applying bacterial colonies without further protein extraction. A total of 40 K. pneumoniae and 114 other related microorganisms isolated clinically were analyzed by SELDI-TOF MS. An identification model for K. pneumoniae was established by artificial neural networks (ANNs) with classification accuracy of 100%. The model was blindly tested with 43 K. pneumoniae and 53 control bacteria again. The results showed that the model was successful with accuracy of 96.9%, sensitivity of 100% and specificity of 94.3%. This strategy is potential for rapid identification of K. pneumoniae.

Cancer Prediction Based on Radical Basis Function Neural Network with Particle Swarm Optimization

Yan, Xiao-Bo,Xiong, Wei-Qing,Hu, Liang,Zhao, Kuo Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18

This paper addresses cancer prediction based on radial basis function neural network optimized by particle swarm optimization. Today, cancer hazard to people is increasing, and it is often difficult to cure cancer. The occurrence of cancer can be predicted by the method of the computer so that people can take timely and effective measures to prevent the occurrence of cancer. In this paper, the occurrence of cancer is predicted by the means of Radial Basis Function Neural Network Optimized by Particle Swarm Optimization. The neural network parameters to be optimized include the weight vector between network hidden layer and output layer, and the threshold of output layer neurons. The experimental data were obtained from the Wisconsin breast cancer database. A total of 12 experiments were done by setting 12 different sets of experimental result reliability. The findings show that the method can improve the accuracy, reliability and stability of cancer prediction greatly and effectively.

Percutaneous catheter drainage for abscess after surgery

Wen-Bo Zhu,Xiao-Hui Zhao,Hai-Liang Li,Chen-Yang Guo,Quan-Jun Yao,Xiang Geng,Ke Zhao,Hong-Tao Hu 소화기인터벤션의학회 2022 International journal of gastrointestinal interven Vol.11 No.4

Percutaneous abscess drainage (PAD) has been proven to be a safe, effective, and widely used technique for the treatment of patients with abscesses after gastrointestinal surgery. The indications for PAD are expanding and most postoperative abscesses of the gastrointestinal tract are susceptible to PAD. PAD uses various imaging methods, including ultrasound, computed tomography, and several safe and reliable catheter insertion methods.

An Arabidopsis SUMO E3 Ligase, SIZ1, Negatively Regulates Photomorphogenesis by Promoting COP1 Activity

Lin, Xiao-Li,Niu, De,Hu, Zi-Liang,Kim, Dae Heon,Jin, Yin Hua,Cai, Bin,Liu, Peng,Miura, Kenji,Yun, Dae-Jin,Kim, Woe-Yeon,Lin, Rongcheng,Jin, Jing Bo Public Library of Science 2016 PLoS genetics Vol.12 No.4

<P>COP1 (CONSTITUTIVE PHOTOMORPHOGENIC 1), a ubiquitin E3 ligase, is a central negative regulator of photomorphogenesis. However, how COP1 activity is regulated by post-translational modifications remains largely unknown. Here we show that SUMO (small ubiquitin-like modifier) modification enhances COP1 activity. Loss-of-function siz1 mutant seedlings exhibit a weak constitutive photomorphogenic phenotype. SIZ1 physically interacts with COP1 and mediates the sumoylation of COP1. A K193R substitution in COP1 blocks its SUMO modification and reduces COP1 activity in vitro and in planta. Consistently, COP1 activity is reduced in siz1 and the level of HY5, a COP1 target protein, is increased in siz1. Sumoylated COP1 may exhibits higher transubiquitination activity than does non-sumoylated COP1, but SIZ1-mediated SUMO modification does not affect COP1 dimerization, COP1-HY5 interaction, and nuclear accumulation of COP1. Interestingly, prolonged light exposure reduces the sumoylation level of COP1, and COP1 mediates the ubiquitination and degradation of SIZ1. These regulatory mechanisms may maintain the homeostasis of COP1 activity, ensuing proper photomorphogenic development in changing light environment. Our genetic and biochemical studies identify a function for SIZ1 in photomorphogenesis and reveal a novel SUMO-regulated ubiquitin ligase, COP1, in plants.</P>