키넥트 센서를 이용한 고령자 대상의 선자세 균형능력 평가

양승태(Seung-Tae Yang),강동원(Dong-Won Kang),서정우(Jeong-Woo Seo),김대혁(Dae-Hyeok Kim),김태호(Tae-Ho Kim),최진승(Jin-Seung Choi),탁계래(Gye-Rae Tack) 대한전기학회 2017 전기학회논문지 Vol.66 No.2

Portable low-cost Kinect sensor was used to analyze standing balance ability of the elderly. Eighty subjects who can walk alone and have a normal cognitive level participated in this experiment. Based on Berg Balance scale (BBS) test with 52 points, subjects were divided into Healthy older (HO: 46 persons, BBS: 53.80 ± 1.19) and Impaired older (IO: 34 persons, BBS: 49.06 ± 2.03) group. Each subject performed 30 seconds four different standing balance tests (EO: Eyes Open, EC: Eyes Close, EOf: Eyes Open on foam, ECf: Eyes Close on foam). Five variables (Mean distance, Range of distance, Root mean square, Mean velocity, 95% ellipse area) were calculated from the hip joint center movement of Kinect sensor. Results showed that there were significant differences between groups for four different standing tests. Calculated variables from kinect sensor showed significant correlation with BBS score. Especially, mediolateral mean distance, mediolateral root mean square, mediolateral range of distance and 95% ellipse area showed discriminative ability for all tests. Mean values of variables of IO were higher than those of HO, which means the decreased balance ability in IO compared with HO. Therefore, it was possible to estimate simple balance assessment of the elderly using portable low-cost Kinect sensor.

대장암 환자에서의 담즙 암태아성 항원(CEA)

김종우,박용태,정철운,권성원,장항석,손석우,안대호,이경포 대한대장항문학회 2000 Annals of Coloproctolgy Vol.16 No.6

복부기형혈관의 문맥-체순환 단락으로 유발된 만성 후천성 간뇌 퇴행중 1례

김대현,김종국,차재관,김상호,김재우 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

Unity 3D Engine을 이용한 3D FPS 게임

박대호, 박동원, 안성옥, 김수균, 이현우 배재대학교 공학연구소 2012 공학논문집 Vol.14 No.1

Emerging and one complete game engine, Unity 3D Engine by the FPS genre of games were produced. Unity 3D Engine to provide several features in the production of the game, basically, terrain making, Unity 3D Engine from collision, particle effects and AI of the enemies is set to create a game using only one genre FPS not be enough to be an element of fun to think that the basic framework of the FPS genre adventure genre of games by adding the elements of the game more fun.

체성감각 유발전위중 Nl8 Far-field 전위의 비강인두를 통한 접근

김대현,차재관,김상호,김재우 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

신증후출혈열 백신 한타박스 접종자에서의 면역반응 및 항체지속 기간에 관한 연구

우영대,주용규,이호왕 대한감염학회 1998 감염 Vol.30 No.4

목 적 : 우리나라에서 한탄바이러스와 서울 바이러스에 의하여 발생하는 신증후출혈열을 예방하기 위하여 1990년 개발된 한타박스는 현재 상용화되어 있다. 한타박스가 시중에서 상용화되어 사용된 역사가 짧으므로, 예방접종자에서 항체지속기간에 관한 연구는 미흡한 실정이다. 본 연구에서는 신증후출혈열 예방백신인 한타박스를 접종한 사람들에서의 항체 특히 중화항체양전율과 항체지속기간을 조사하고자 하였다. 방 법 : 아산생명과학연구소에 근무하는 61명의 연구원들을 대상으로 신증후출혈열 예방백신인 한타박스를 한달간격으로 2회 기본접종하였다. 예방백신을 접종하기 전 대상자들이 혈청을 채취하여 한탄바이러스와 서울바이러스에 대한 항체음성임을 형광항체법과 중화항체법으로 확인하였다. 한타박스를 기본접종한 한달 후 및 일년 후 그리고 기본 접종한지 일년이 경과하여 1차 부스터 접종을 한 한달 후 및 2년여가 경과한 후와 2차 부스터 접종 한달 후의 백신접종자에서의 항체양성율 및 항체가를 간접면역형광항체법(IFA), 고비중입자응집반응(HDPA) 및 플라크감소 중화시험(PRNT) 등으로 비교 측정하여 배신접종자에서의 항체양성율, 형광항체가 및 중화항체가와 면역지속기간을 조사하였다. 결 과 : 1) 신증후출혈열 백신인 한타박스를 2회 기본접종을 하고 한달 후 혈청을 채취한 21명에서의 IFA, HDPA와 PRNT방법에 의한 항체양성율은 각각 20/21 (95.2%), 19/21 (90.5%), 14/21 (66.7%)이었으며, 평균 항체역가는 각각 262,248,120이었다. 2) 기본접종 1면 후 혈청을 채취한 40명에서의 IFA, HDPA와 PRNT방법에 의한 항체양성율은 저하되어 각각 25/40 (62.5%), 18/40 (45.0%) 그리고 9/40 (22.5%)이었으며 평균 항체역가는 각각 92,41,24.5 이었다. 3) 부스터접종이 효과를 조사하여 본 결과 기본접종 1년후 채혈한 14명에서의 IFA와 PRNT방법에 의한 항체양성율은 7/14 (50.0%), 3/14 (21.4%)이었으며 평균 항체역가는 각각 100.6, 47.1 이었다. 1차 부스터 접종 한 14명중 1개월후 채혈한 8명의 IFA와 PRNT방법에 의한 항체양성율은 8/8(100%), 8/8(100%)이었으며 평균 항체역가는 각각 852,182.5 이었다. 1차 부스터 접종한 20개월후 채혈된 12명의 항체양성율은 11/12 (91.7%), 9/12 (75.0%)이었으며 평균 항체역가는 각각 296, 33.3 이었고, 2차 부스터 접종한 3개월 후 채혈한 7명의 항체양성을율은 7/7 (100%), 6/7(85.7%)으로 항체 평균역가는 각각 548,46 이었따. 기본접종 1년후 1차부스터접종을 실시한 1개월후 채혈한 8명의 항체역가와 2차부스터접종을 실시한 한달후 채혈한 7명의 항체역가를 형광항체법과 중화항체법으로 조사한 결과 뚜렷한 항체역가의 증가를 나타내는 기왕성면역반응을 볼 수 있었다. 결 론 : 백신접종자에서 한탄바이러스에 대한 항체를 높게 유지하기 위해서는 2회의 기본접종과 기본접종 1년후 추가접종이 필요하며, 추가접종후 최소한 2년간은 항체가 지속적으로 유지된다는 사실을 증명하였다. Background : Hantavax™ was developed and has been used for prevention of hemorrhagic fever with renal syndrome caused by Hantaan and Seoul virus since 1990 in Korea. Since Hantavax™ has short usage history, the duration of antibodies persistancy in vaccinees was not well studied. Methods : Hantavax™ was inoculated to 61 people who work at Asan Institue for Sciences twice subcutaneously at one month interval according to the manufacturer's recommendation. Antibody titers of vaccinees were measured at 1∼4 months or 1 year after primary basic vaccination and a month, 1∼2 years after booster vaccination by indirect immunofluorescent assay (IFA), High density particle agglutination assay (HDPA), and plaque reduction neutralization test (PRNT). Results : Serconversion of twentyone vaccinees on 1∼4 months after primary vaccination were 20/21 (95.2%), 19/21 (90.5%) and 14/21 (66.7%) whose geometric mean antibody titers were 262,248,120; Forty vaccinees on one year after primary vaccination were 25/40 (62.5%), 18/40 (45.0%), 9/40 (22.5%) whose geometric mean antibody titers were 90,56,24 by IFA, HDPA, PRNT, respectively. Seroconversion of eight vaccinees on one month after booster vaccination were 11/12 (91.7%), 9/12 (75.0%) whose mean antibody titers were 296,33, and seven vaccinees on 3 months after second booster vaccination were 7/7 (100%), 6/7 (85.7%) whose mean antibody titers were 54,946 by IFA, PRNT, respectively. Conclusion : The boost vaccination is necessary at 12 months after primary basic vaccination of Hantavax™ for maintaining high level of antibodies against of Hantaan virus, and antibodies persist at least two years.

치근단 절제술 시행 2년 후의 치근단 병소 치유 증례

손호현,박정기,최대우 全北大學校 齒醫學硏究所 1985 전북치대논문집 Vol.3 No.1

A 27-year-old Korean woman presented with intermittent dull pain at the periapical area of the maxillary right lateral incisor. At the periapex of the tooth radiolucency was observed. Clinical examination revealed the open pulp chamber, foul, odor, slight mobility and tenderness to percussion. Diagnosis was made as periapical granuloma secondary to pulp necrosis. Conventional root canal therapy was done and the canal were sealed permanently with gutta-percha and zinc oxide-eugenol sealer and finally apicoectomy was performed. Twenty-two months later, standard periapical film of the tooth showed the increasing periapical radiopacity suggesting bon regeneration. Any clinical symptoms were abscent and the maxillary right lateral incisor functioned normally.

용접 근로자의 혈액 및 요중 망간 농도

현대우,안선희,김강윤,최호춘 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4

Blood and urine samples were taken from 447 welders exposed to manganese containing welding fumes and 127 office workers not exposed to welding fumes as a control. The air samples were analyzed by flame atomic absorption spectrophotometer(Varian 30A, Australia), and blood and urine samples were analyzed by flameless atomic absorption spectrophotometer(Z-8100, Hitachi, Japan). Data were evaluated in accordance with type of industry, smoking habits, and work duration. The results obtained were as follows: 1. The limit of detection(LOD) levels of manganese in blood and urine were 0.11㎍/100㎖ and 0.14㎍/ι, respectively. Our results of manganese concentration were shown within ±2 standard deviation which was the upper and lower warning limit(UWL or LWL) on quality control chart. 2. The airborne concentrations of manganese in welding workplaces were 0.067㎎/㎥ showing differences by type of industry; 0.017㎎/㎥ in automobile assembly and manufacturing industries, 0.084㎎/㎥ in steel heavy industries and 0.180㎎/㎥ in shipyards. 3. The blood manganese concentrations showed differences by type of industry showing the highest values of 1.70㎍/100㎖ in shipyards, 1.24㎍/100㎖ in automobile assembly and manufacturing industries and 1.111㎍/100㎖ in steel heavy industries. Urinary manganese concentration corrected by urinary creatinine concentrations was 0.34㎍/g creatinine in automobile assembly and manufacturing industries, 0.43㎍/g creatinine in steel heavy industries and 0.48㎍/g creatinine in shipyards. There were no difference urinary manganese concentrations by type of industry. 4. The overall blood manganese concentration was 1.26㎍/100㎖, and urinary manganese concentration was 0.35㎍/g creatinine in welders. In contrast to these values, blood and urinary manganese concentrations were lower in control group showing 0.73㎍/100㎖,, and 0.28㎍/g creatinine, respectively. 5. Smoking habits did not seem to affect on blood and urinary manganese concentrations both in welders and office workers. 6. Blood manganese concentrations were significantly higher in welder who had worked longer than 10 years than in welder who had worked less than 10 years. 7. The blood manganese concentrations were significantly correlated to airborne manganese concentrations(r=0.318, n=64), work duration(r=0.425, n=538), and cumulative exposure indices(CEI) (r=0.354, n=64).

薄板의 加工性에 미치는 異方性에 관한 硏究(Ⅰ)

徐大敎,金東哲,禹鎬吉 충남대학교 공업교육연구소 1981 論文集 Vol.4 No.1

This study is concerned with the anisotropy which affects the workability of several different sheet metals. To do this, authors studied the earing through the deep drawing process, using the results which were obtained by studying the effect of the anisotropy of sheet metal in tensile yielding. The results through this study are as follows; 1) The corresponding maximum errors of the theoretical and experimental results in steel, brass, and aluminum plates in tensile yielding are 16%, 6%, and 5% respectively. 2) The earing of steel, brass and copper plates whose thickness are 0.62㎜ are two or three times as high as those of corresponding plates whose thickness are 0.34㎜. 3) The assumption of costa is satisfied in steel plate, but it is not satisfied in brass plate. It is hoped that the results of this study will be made reference to other works of sheet metal.

Cyanobacterium Synechocystis PCC6803 내에서 Bacillus thuringiensis subsp. morrisoni PG-14 cryIVD 유전자의 발현

이대원,박현우,진병래,정영호,박영목,강석권 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.2

미생물 살충제로 사용되고 있는 B. thuringiensis를 모기유충방제에 적용하기 위한 시도는 B. thuringiensis가 수서생태계에서 부유하지 못하고 가라앉으며, 생활환을 이루지 못한다는 문제점으로 인해 적용에 어려움이 있다. 따라서 본 연구는 모기유충에 강한 독성을 갖는 B. thuringiensis subsp. morrisoni PG-14의 cryIVD 유전자를 모기유충의 먹이인 cyanobactrium에 도입하기 위하여 발현벡터 pCYASK 5-1을 제작하고, cyanobacterium Synechocystis PCC6803에 형질전환시켜, 세포내에서 cryIVD 유전자의 발현과 뇌염모기에 대한 독성을 조사하였다. 그 결과 형질전환체 내에서 cryIVD 발현은 immunoblot 분석을 통해 B. thuringiensis subsp. morrisoni PG-14에서 발현된 단백질과 같은 분자량으로 발현되는 것을 확인하였으며, 모기유충에 대한 형질전환체의 독성은 1.40×10^6 cells/ml 농도에서 약 80%의 치사율을 나타내었다. Bacillus thuringiensis subsp. morrisoni PG-14 is a gram-positive soil bacterium producing mosquitocidal parasporal inclusions composed of several crystal proteins. Among these crystal protein genes, cryIVD gene is one of major component which has 72 kDa in size. However, these parasporal inclusions sink quickly from the surface of water where mosquito larval feeding occurred. To develope mosquitocidal cyanobacterium, therefore, we constructed the expression vector, pCYASK 5-1 harboring cryIVD gene. The expression vector, pCYASk5-1 was transformed into the cyanobacterium Synechocystis PCC6803 reported as a natural mosquito larval food source and the transformants were selected with kanamycin. Expression of cryIVD gene in transformant was characterized by SDS-polyacrylamide gel electrophoresis (PAGE) and immunoblot analysis. The mosquitocidal activity of a transformant was determined electrophoresis (PAGE) and immunoblot analysis. The mosquitocidal activity of a transformant was determined with Culex tritaeniorhynchus. The results showed that the transformed cyanobacterium is toxic to mosquito larvae and will be expected as a potential agent that is used for mosquito control.