성인 지역사회 폐렴의 원인 미생물에 대한 전향적 다기관 연구 : Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi

김민자,정희진,손장욱,심희선,박대원,박승철,우준희,강재명,김유겸,신완식,김양리,이환종,김지희 대한감염학회 2001 감염 Vol.33 No.1

Background : Despite rigorous investigations, the etiology of community-acquired pneumonia remains unknown in about 50% of hospitalized patients. The diagnosis of the etiological agent is becoming more challenging and more critical as number of newer pathogens have been recognized in recent years. In the 3-year period prospective study we investigated adult patients with community-acquired pneumonia for Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi as potential etiologic agents. Methods : A prospective multicenter study was performed from May 1997 to April 2000. A total of 431 patients with community-acquired pneumonia under the inclusion criteria were examined for specific microbial diagnosis; sputum culture and PCR, and serologic teats including indirect immunofluorescence antibody (IFA) test for Legionella, and hemagglutination tests for Leptosoira, Hantaan virus and O. tsutsugamushi. Etiologic diagnosis was determined on the basis of the review of case record forms and specific laboratory diagnostic criteria. Results : During the study period a total of 385 sputum and 283 serum samples were examined. Legionella pneumonia was diagnosed in 2.3% (10/431) of the cases examined : 1.4% cases with PCR-positive (5/367) and 2.1% with positive IFA test (6/283). Leptospirosis and scrub typhus were diagnosed in 0.4% (1/252) and 2.0% (5/252), respectively. All 5 cases with scrub typhus occurred in late fall, and rash or eschar was not found. None of cases was Hantaan virus infection. Conclusion : The results suggest that Legionella, Leptospira, and O. tsutsugamushi should be considered in the etiologic diagnosis and empirical antibiotic therapy of community-acquired pneumonia. (Korean J Infect Dis 32:24∼31, 2001)

다발성 대장암 간전이 환자의 간절제를 위한 새로운 시도

주종우,김형철,임철완,신응진,조규석,유기원,송옥평,홍대식,박성진,조준희,이혜경,김희경,권계원,고은석 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Multiple bilobar liver matastases (MBLM) are the main cause of low resectability in the colon cancer liver metastases. The authors experienced one case of initially non-resectable colon cancer liver metastases. He was curatively and safely treated with a two-stage hepatectomy using the new method of future remnant liver volume growing. A 54-year-old man was referred to our department with the sigmoid colon cancer combined with MBLM, which were checked in two small metastatic lesions in the left lobe and five large sized lesions in the right lobe in the computed tomogram (CT). A laparoscopic assisted anterior resection was primarily performed. We performed the 1^(st) stage hepatectomy 3 weeks after the colon resection. Intra-operative Ultrasonogram (US) found 9 small superficial metastatic lesions in the left lobe. All that lesions were completely removed by non-anatomical wedge resection. An occlusion ballon catheter was placed in the right portal vein through a small branch of the inferior mesenteric vein at that time. The future remnant liver volume was sufficiently increased 3 weeks after the 1^(st) hepatectomy. A right hepatectomy was safely performed 22 days after the 1^(st) hepatectomy. The patient received a regional chemotherapy (interleukin2 based immuno-chemotherapy through hepatic artery) for 4 months, then received 9 cycles of systemic chemotherapy (biweekly Oxaliplation, leucovorin, plus 5-fluorouracil) without any recurrence evidence.

인트라넷을 기반으로 한 구매 시스템의 설계 및 구현

김창근,김완규,김흥준 진주산업대학교 2000 산업과학기술연구소보 Vol.- No.7

As the uses of WWW are growing, the uses of internet and intranet are growing too. Many companies put into operation the computerization of job processing using the intranet. However, in the majority of the cases, intranets are limited by bulletins board, information floor and chatting room in the function. In this paper, internet shopping mall typed Procurement system based on intranet is designed and implemented.

CORBA 클라이언트/서버 구조의 자바 통합 개발 환경의 설계 및 구현

김완수,김흥준,박순규 진주산업대학교 2000 산업과학기술연구소보 Vol.- No.7

Today, most of the well-known software development tools and methods faced with problems of scalability, modularity, granularity, and maintenance. These problems result in the fact that these tools and methods are standalone. In this paper, we propose a design and implementation of software development environment for Java application based upon CORBA-based Client/Server model. Proposed model has facilities to overcome a problem caused by updates and its distribution and is possible to overcome problems of scalability, modularity and granularity because it based upon Client/Server model.

보강재의 형상이 평판의 고유진동수에 미치는 영향에 관한 연구

金泰玩,姜俊洙,表東根 弘益大學校 科學技術硏究所 1995 科學技術硏究論文集 Vol.6 No.-

An analysis is presented for the free vibration of a cantilever plate. For this papers, there are compared with the stiffener, I-shape and T-shape of the plate. The method is applied to cantilever plate with stiffened plate, I-shape and T-shape, and the natural frequencies and mode shapes of vibration are calculated numerically, given the results and confirmed experimentally.

개불(Ureshis unicinctus) 受精卵의 卵割類型과 形態形成에 關한 硏究

김완종,최준섭,신길상 순천향대학교 기초과학연구소 1995 순천향자연과학연구 논문집 Vol.1 No.2

The present study was carried out to examine the early embryogenesis of Urechis unicinctus in terms of its cleavage pattern and morphogenesis. The first sign of fertilization was the appearance of fertilization membrane, which was 20㎛ in maximum thickness. The cleavage pattern was equal holoblastic in early stage and partial unequal cleavage in later stage. There appeared the cavity in blastula, and then cilia which were derived from the peripheral blastomeres, activated the motility of the larva. Ultrastructures of cleaving zygote included microvilli on free cell surface, numerous nuclear pores of nucleus, well developed rough endoplasmic reticulum, Golgi complex and mitochondria in the cytoplasm. In addition, yolk granules and vesicles were also distributed in the cytoplasm. Cytokinesis was followed by the karyokinesis, through the formation of the cleavage furrow. Morphogenesis of Urechis unicinctus is summarized by the serial equal holoblastic cleavages, the cell movements, and the formations of a blastocoel and cilia.

치수생활력 검사를 위한 Laser Doppler flowmeter의 이용

김영진,남순현,김현정,서완종 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.3

저자는 본 병원에 내원한 환자중 미완성치구근단을 가지고 있으며 외상받은 치아 및 자가이식치아를 대상으로 기존의 치수생활력 검사방법과 더불어 LDF를 이용한 검사방법을 통해 다음과 같이 요약할 수 있다. 1. 치수 생활력 유무를 판단함에 있어 현재까지 널리 사용된 전기치수검사, 냉검사등의 방법은 치수 내 신경발달 정도 및 피검자의 주관에 의해 반응이 다르게 나타나는 경우가 많다. 2. 이에 반해 LDF를 이용한 치수생활력 검사방법은 위음성 및 위양성 반응의 빈도가 낮아 신뢰도가 높으며 비교적 조기에 치수생활력을 특정할 수 있는 우수한 방법이다. Various diagnostic methods, such as electric pulp test, cold test, cavity etc, have been used to determine the pulp vitality. At least two or more methods should be used with supplemental information to diagnose each case because using one method doesn't provide sufficient accuracy. These conventional methods have depended on nervous responses, but laser Doppler Flowmeter determines the pulp vitality by measuring pulpal blood flow. In this case, we tested the vitality of the traumatized teeth with incomplete root apices and autotransplanted teeth with conventional methods and Laser Doppler Flowmeter . Conventional methods. such as electric pulp test and cold test can produce various responses according to the development state of the pulpal nerve and the sensory threshold of the patient. but ,laser doppler Flowmeter has a lower false response rate than other pulp vitality test methods and it can determine the vitality somewhat earlier than the other method.

비유기중의 소유방염에 대한 항균펩타이드(Buforin Ⅱb)의 효능실험

김인송,권성균,임형준,이완규 한국수의공중보건학회 2002 예방수의학회지 Vol.26 No.3

Recently, a novel antimicrobial peptide including Buforin II has been emphasized to kill multi-drug resistant bacteria and avoid promoting multi-drug resistance. This study evaluated the efficacy of an antimicrobial peptide (Buforin IIb) on bovine mastitis. Based on the Minimum inhibitory concentration(MIC, 4 g/ml) of Buforin IIb, syringes were made five concentration(MIC×10, ×50, ×100, ×300, and ×500). Thirty three cows(38 quarters) with bovine mastitis were selected using California mastitis test and grouped in dependant on drug concentration and treatment duration. Each group treated by intramammary infusion twice a day for 3 5 days. The milk samples of 5 groups were aseptically collected from quarters at 0, 3, 7 and 14 days, and 2 groups were collected at 0, 5, 9 and 14 days after first treatment. Collected samples were used for bacterial culture and somatic cell count. Bacterial number(log_(10) mean CFU/ml) was decreased in dependant on drug concentration and extending treatment duration. In group D(MIC×300), bacterial number was decreased from 4.59±0.10(day 0) to 2.89±1.37(day 3), 4.04±0.33(day 7), and 4.19 ± 0.10(day 14), respectively(p 0.05). Bacterial number of B2(MIC×50, 5 days treated) is decreased, approximately 10%, than group B1(MIC×50, 3 days treated). Somatic cell count of group D was slightly decreased from 11,100(×10³)(day 0), to 7,386(×10³)(3 day), 6,886(×10³)(day 7), and 9,661(×10³)(day 14). Staphylococcus spp., was the most common isolate, was bacteriologically cured 100% by Buforin IIb treatment. Overall results indicate that Buforin IIb could have possibility to cure bovine mastitis, if higher concentration over experimental concentration were treated with extending treatment duration.

생리식염수 전기분해에 의한 세균 오염된 콘택트렌즈의 살균

김완석, 박준오, 최영기, 이영민, 김형규, 차은종, 김석용 충북대학교 동물의학연구소 2007 Journal of Biomedical and Translational Research Vol.8 No.1

본문참고

汚物收去車輛의 最適 route設定에 관한 硏究

金正子,李相玩 동아대학교 환경문제연구소 1980 硏究報告 Vol.4 No.1

This study is considered for the rationalization of collection transportation system by the technique of O.R. To improve the present environmental public pollution condition, selecting a sample model, investigating and analyzing it's distribution route, we could determine optimum route to garbage collection vehicles. Actually, by the result of application to Young-Do district, we could reduce 5㎞ per day in distance and it's all expenditures concerned with time and transportation. But, for realization of this study, we have to consider traffic system.