Gradient doping simulation of perovskite solar cells with CH3NH3Sn1−xPbxI3 as the absorber layer

Yang Qingchen,Yang Sui,Xi Tingting,Li Hongxing,Yi Jie,Zhong Jianxin 한국물리학회 2022 Current Applied Physics Vol.44 No.-

In this study, we built a perovskite solar cells(PSCs) model with a Au/CuSCN/CH3NH3Sn1-xPbxI3/TiO2/FTO glass structure using the SCAPS program and use polynomial fitting to obtain the relationship between the conduction/valence bands of CH3NH3Sn1-xPbxI3 and the x value, which is more complex and accurate than that in any previous research. The influences of thickness, electron and hole mobilities, relative permittivity, effective conduction band density, effective valence band density, and the value of x on the solar cell performance are analyzed. Furthermore, we simulate the situation where the doping concentration changes with the absorption layer depth of the device and a special bandgap is formed. The power conversion efficiency of the device improves from 19.96% to 20.52%, with an open-circuit voltage of 0.776 V, a short-circuit current of 33.79 mA/cm2, and a filling factor of 77.39% when double gradient doping is performed. The application value of gradient doping in the device absorption layer is obtained.

Starfy Cat Princess

Tingting Yang 한국콘텐츠학회 2023 ICCC International Digital Design Invitation Exhib Vol.2023 No.5

Zearalenone exposure affects the Wnt/β-catenin signaling pathway and related genes of porcine endometrial epithelial cells in vitro

Song Tingting,Yang Weiren,Huang Libo,Yang Zaibin,Jiang Shuzhen 아세아·태평양축산학회 2021 Animal Bioscience Vol.34 No.6

Objective: Zearalenone (ZEA) has estrogen-like effects. Our previous study has shown that ZEA (0.5 to 1.5 mg/kg) could induce abnormal uterine proliferation through transforming growth factor signaling pathway. To further study the other regulatory networks of uterine hypertrophy caused by ZEA, the potential mechanism of ZEA on porcine endometrial epithelial cells (PECs) was explored by the Illumina Hiseq 2000 sequencing system. Methods: The PECs were treated with ZEA at 0 (ZEA0), 5 (ZEA5), 20 (ZEA20), and 80 (ZEA80) μmol/L for 24 h. The collected cells were subjected to cell cycle, RNA-seq, real-time quantitative polymerase chain reaction, immunofluorescence, and western blot analysis. Results: The proportion of cells in the S and G2 phases decreased (p<0.05), but the proportion of cells in the G1 phase increased (p<0.05) in the ZEA80 treatment. Data analysis revealed that the expression of Wnt pathway-related genes, estrogen-related genes, and mitogen-activated protein kinase pathway-related genes increased (p<0.05), but the expression of genetic stability genes decreased (p<0.05) with increasing ZEA concentrations. The relative mRNA and protein expression of WNT1, β-catenin, glycogen synthase kinase 3β (GSK-3β) were increased (p<0.05) with ZEA increasing, while the relative mRNA and protein expression of cyclin D1 (CCND1) was decreased (p<0.05). Moreover, our immunofluorescence results indicate that β-catenin accumulated around the nucleus from the cell membrane and cytoplasm with increasing ZEA concentrations. Conclusion: In summary, ZEA can activate the Wnt/β-catenin signaling pathway by upregulating WNT1 and β-catenin expression, to promote the proliferation and development of PECs. At the same time, the up-regulation of GSK-3β and down-regulation of CCND1, as well as the mRNA expression of other pathway related genes indicated that other potential effects of ZEA on the uterine development need further study. Objective: Zearalenone (ZEA) has estrogen-like effects. Our previous study has shown that ZEA (0.5 to 1.5 mg/kg) could induce abnormal uterine proliferation through transforming growth factor signaling pathway. To further study the other regulatory networks of uterine hypertrophy caused by ZEA, the potential mechanism of ZEA on porcine endometrial epithelial cells (PECs) was explored by the Illumina Hiseq 2000 sequencing system.Methods: The PECs were treated with ZEA at 0 (ZEA0), 5 (ZEA5), 20 (ZEA20), and 80 (ZEA80) μmol/L for 24 h. The collected cells were subjected to cell cycle, RNA-seq, real-time quantitative polymerase chain reaction, immunofluorescence, and western blot analysis.Results: The proportion of cells in the S and G2 phases decreased (p<0.05), but the proportion of cells in the G1 phase increased (p<0.05) in the ZEA80 treatment. Data analysis revealed that the expression of Wnt pathway-related genes, estrogen-related genes, and mitogen-activated protein kinase pathway-related genes increased (p<0.05), but the expression of genetic stability genes decreased (p<0.05) with increasing ZEA concentrations. The relative mRNA and protein expression of WNT1, β-catenin, glycogen synthase kinase 3β (GSK-3β) were increased (p<0.05) with ZEA increasing, while the relative mRNA and protein expression of cyclin D1 (CCND1) was decreased (p<0.05). Moreover, our immunofluorescence results indicate that β-catenin accumulated around the nucleus from the cell membrane and cytoplasm with increasing ZEA concentrations.Conclusion: In summary, ZEA can activate the Wnt/β-catenin signaling pathway by up-regulating WNT1 and β-catenin expression, to promote the proliferation and development of PECs. At the same time, the up-regulation of GSK-3β and down-regulation of CCND1, as well as the mRNA expression of other pathway related genes indicated that other potential effects of ZEA on the uterine development need further study.

Primary Invasive Mucinous Adenocarcinoma of the Lung: Prognostic Value of CT Imaging Features Combined with Clinical Factors

Wang Tingting,Yang Yang,Liu Xinyue,Deng Jiajun,Wu Junqi,Hou Likun,Wu Chunyan,She Yunlang,Sun Xiwen,Xie Dong,Chen Chang 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.4

Objective: To investigate the association between CT imaging features and survival outcomes in patients with primary invasive mucinous adenocarcinoma (IMA). Materials and Methods: Preoperative CT image findings were consecutively evaluated in 317 patients with resected IMA from January 2011 to December 2015. The association between CT features and long-term survival were assessed by univariate analysis. The independent prognostic factors were identified by the multivariate Cox regression analyses. The survival comparison of IMA patients was investigated using the Kaplan-Meier method and propensity scores. Furthermore, the prognostic impact of CT features was assessed based on different imaging subtypes, and the results were adjusted using the Bonferroni method. Results: The median follow-up time was 52.8 months; the 5-year disease-free survival (DFS) and overall survival rates of resected IMAs were 68.5% and 77.6%, respectively. The univariate analyses of all IMA patients demonstrated that 15 CT imaging features, in addition to the clinicopathologic characteristics, significantly correlated with the recurrence or death of IMA patients. The multivariable analysis revealed that five of them, including imaging subtype (p = 0.002), spiculation (p < 0.001), tumor density (p = 0.008), air bronchogram (p < 0.001), emphysema (p < 0.001), and location (p = 0.029) were independent prognostic factors. The subgroup analysis demonstrated that pneumonic-type IMA had a significantly worse prognosis than solitary-type IMA. Moreover, for solitary-type IMAs, the most independent CT imaging biomarkers were air bronchogram and emphysema with an adjusted p value less than 0.05; for pneumonic-type IMA, the tumors with mixed consolidation and ground-glass opacity were associated with a longer DFS (adjusted p = 0.012). Conclusion: CT imaging features characteristic of IMA may provide prognostic information and individual risk assessment in addition to the recognized clinical predictors.

Performance study of g-C3N4/carbon black/BiOBr@Ti3C2/MoS2 photocatalytic fuel cell for the synergistic degradation of different types of pollutants

Guo Huilin,Yu Tingting,Zhao Lei,Qian Jun,Yu Jiahe,Zhang Yu,Teng Yongyue,Zhu Chunshui,Yang Tao,Chen Wenbin,Gong Picheng,Jiang Cuishuang,Gao Changfei,Yang Bing,Yang Chenyu 한국탄소학회 2023 Carbon Letters Vol.33 No.3

In this study, a bipolar visible light responsive photocatalytic fuel cell (PFC) was constructed by loading a Z-scheme g-C3N4/carbon black/BiOBr and a Ti3C2/MoS2 Schottky heterojunction on the carbon brush to prepare the photoanode and photocathode, respectively. It greatly improved the electron transfer and achieved efficient degradation of organic pollutants such as antibiotics and dyes simultaneously in two chambers of the PFC system. The Z-scheme g-C3N4/carbon black/BiOBr formed by adding highly conductive carbon black to g-C3N4/BiOBr not only effectively separates the photogenerated carriers, but also simultaneously retains the high reduction of the conduction band of g-C3N4 and the high oxidation of the valence band of BiOBr, improving the photocatalytic performance. The exceptional performance of Ti3C2/MoS2 Schottky heterojunction originated from the superior electrical conductivity of Ti3C2 MXene, which facilitated the separation of photogenerated electron–hole pairs. Meanwhile, the synergistic effect of the two photoelectrodes further improved the photocatalytic performance of the PFC system, with degradation rates of 90.9% and 99.9% for 50 mg L−1 tetracycline hydrochloride (TCH) and 50 mg L−1 rhodamine-B (RhB), respectively, within 180 min. In addition, it was found that the PFC also exhibited excellent pollutant degradation rates under dark conditions (79.7%, TCH and 97.9%, RhB). This novel pollutant degradation system is expected to provide a new idea for efficient degradation of multiple pollutant simultaneously even in the dark.

A Dual Functional Ti-Ga Alloy: Inhibiting Biofilm Formation and Osteoclastogenesis Differentiation via Disturbing Iron Metabolism

Fupeng Li,Kai Huang,Jinbing Wang,Kai Yuan,Yiqi Yang,Yihao Liu,Xianhao Zhou,Keyu Kong,Tao Yang,Jian He,Chunjie Liu,Haiyong Ao,Fengxiang Liu,Qian Liu,Tingting Tang,Shengbing Yang 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Background Although biomedical implants have been widely used in orthopedic treatments, two major clinical challenges remain to be solved, one is the bacterial infection resulting in biofilm formation, and the other is aseptic loosening during implantation due to over-activated osteoclastogenesis. These factors can cause many clinical issues and even lead to implant failure. Thus, it is necessary to endow implants with antibiofilm and aseptic looseningprevention properties, to facilitate the integration between implants and bone tissues for successful implantation. To achieve this goal, this study aimed to develop a biocompatible titanium alloy with antibiofilm and anti-aseptic loosening dual function by utilizing gallium (Ga) as a component. Methods A series of Ti-Ga alloys were prepared. We examined the Ga content, Ga distribution, hardness, tensile strength, biocompatibility, and anti-biofilm performance in vitro and in vivo. We also explored how Ga3+ ions inhibited the biofilm formation of Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and osteoclast differentiation. Results The alloy exhibited outstanding antibiofilm properties against both S. aureus and E. coli in vitro and decent antibiofilm performance against S. aureus in vivo. The proteomics results demonstrated that Ga3+ ions could disturb the bacterial Fe metabolism of both S. aureus and E. coli, inhibiting bacterial biofilm formation. In addition, Ti-Ga alloys could inhibit receptor activator of nuclear factor-κB ligand (RANKL)-dependent osteoclast differentiation and function by targeting iron metabolism, then suppressing the activation of the NF-κB signaling pathway, thus, showing their potential to prevent aseptic loosening. Conclusion This study provides an advanced Ti-Ga alloy that can be used as a promising orthopedic implant raw material for various clinical scenarios. This work also revealed that iron metabolism is the common target of Ga3+ ions to inhibit biofilm formation and osteoclast differentiation.

The effect of thymosin-β4 on the wound healing of rat gingival tissues

Tingting Zhu,Kyung Mi Son,Hee Chul Park,Ji Hyun Kwon,Hyeong-Cheol Yang 대한치과재료학회 2013 대한치과기재학회 학술대회 Vol.2013 No.4

Identification and Characterization of a New Alkaline SGNH Hydrolase from a Thermophilic Bacterium Bacillus sp. K91

( Tingting Yu ),( Junmei Ding ),( Qingxia Zheng ),( Nanyu Han ),( Jialin Yu ),( Yunjuan Yang ),( Junjun Li ),( Yuelin Mu ),( Qian Wu ),( Zunxi Huang ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.4

est19 is a gene from Bacillus sp. K91 that encodes a new esterase. A comparison of the amino acid sequence showed that Est19 has typical Ser-Gly-Asn-His (SGNH) family motifs and could be grouped into the SGNH hydrolase family. The Est19 protein was functionally cloned, and expressed and purified from Escherichia coli BL21(DE3). The enzyme activity was optimal at 60°C and pH 9.0, and displayed esterase activity towards esters with short-chain acyl esters (C2-C6). A structural model of Est19 was constructed using phospholipase A1 from Streptomyces albidoflavus NA297 as a template. The structure showed an α/β-hydrolase fold and indicated the presence of the typical catalytic triad Ser49-Asp227-His230, which were further investigated by site-directed mutagenesis. To the best of our knowledge, Est19 is a new member of the SGNH hydrolase family identified from thermophiles, which may be applicable in the industrial production of semisynthetic β-lactam antibiotics after modification.

Men in charge of “real” work and women the office “housework” : Chinese policewomen in the postsocialist era

Tingting Liu,Lijing Yang 이화여자대학교 한국여성연구원 2021 Asian Journal of Women's Studies(AJWS) Vol.27 No.4

This qualitative study seeks to contribute to studies on the gender division of labor by examining how Chinese policewomen cope with the still-socialist or danwei style of human resource management. In the post-socialist market reform era, the police department has gone through significant changes, undertaking greater economic monitoring and social service functions, including more office work, with an increasing emphasis on the harmonious relationship between the police and public or service-oriented work. These changes have led to a larger number of policewomen, but have not led to a more equitable division of labor due to the persistence of familial norms of womanhood and the enduring police service performance evaluation system that prioritizes crime-fighting tasks over public-service duties. Against this backdrop, we find that policewomen display a certain degree of flexibility, utilizing certain feminine traits in their community service work while maintaining a non-feminine and physically robust outlook.

The Novel Efficient Dual-field FIPS Modular Multiplication

( Tingting Zhang ),( Junru Zhu ),( Yang Liu ),( Fulong Chen ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.2

The modular multiplication is the key module of public-key cryptosystems such as RSA (Rivest-Shamir-Adleman) and ECC (Elliptic Curve Cryptography). However, the efficiency of the modular multiplication, especially the modular square, is very low. In order to reduce their operation cycles and power consumption, and improve the efficiency of the public-key cryptosystems, a dual-field efficient FIPS (Finely Integrated Product Scanning) modular multiplication algorithm is proposed. The algorithm makes a full use of the correlation of the data in the case of equal operands so as to avoid some redundant operations. The experimental results show that the operation speed of the modular square is increased by 23.8% compared to the traditional algorithm after the multiplication and addition operations are reduced about (s²-s)/2, and the read operations are reduced about s²-s, where s=n/32 for n-bit operands. In addition, since the algorithm supports the length scalable and dual-field modular multiplication, distinct applications focused on performance or cost could be satisfied by adjusting the relevant parameters.