퇴원한 정신분열병 환자의 외래 통원 치료에 미치는 요인

박기국,원승희,김상헌,김휘동,강병조 대한생물치료정신의학회 1998 생물치료정신의학 Vol.4 No.2

목적 : 저자는 외래 통원 치료를 지속적으로 받는 환자들과 중단한 환자들의 현황을 조사 비교했다. 그리고 외래 통원 치료를 지속적으로 받는 환자들 중 투약 약물 종류에 따른 치료 순응도에 영향을 미칠 수 있는 변인들을 비교했다. 연구 대상과 방법 : 첫 번째 1997년 4월 1일부터 1998년 4월 30일 동안 퇴원한 정신분열병 환자 140명을 대상으로 자료를 조사한 후 분석했다. 두 번째 1998년 5월 18일부터 1998년 6월 17일까지 한달 동안 외래를 방문한 후 순응도 요인에 관한 설문지의 항목을 작성한 46명 환자의 자료를 분석했다. 결과 : 외래 통원 치료를 지속적으로 받는 환자군과 통원 치료를 중단한 환자군을 비교했을 때, 성별, 연령, 교육 수준, 결혼 여부, 직업, 종교, 정신분열병 아형, 발병 연령, 유병 기간, 입원 횟수, 복용 약물들의 하루 총복용 횟수에서 통계학적으로 의미 있는 차이는 없었다. 퇴원 당시 clozapine을 투약했던 환자들에서 외래 치료지속율이 가장 높게 나타났다. 외래 통원 치료를 받는 환자들의 투약 약물 종류군에 따라 경제적 곤란도, 교육 수준, 유병 기간, 입원 횟수에서 유의한 차이가 있었다. 약물 종류군(clozapine, risperidone, typical anti-psychotics)에 따라 경제 상태, 향후 기대 치료 기간, 약물에 대한 인식도, 약물 효과에 대한 기대, 현재 약의 부작용, 약물의 부작용 경험도, 성별, 연령, 결혼 여부, 직업, 종교, 정신분열병 아형, 발병 연령, 1일 약물 복용 총 횟수의 차이가 없었다. 결론 : 클로자핀 약물을 투약한 환자들이 다른 종류의 항정신병 약물 투약 환자들에 비해 외래 통원 치료를 지속적으로 받는 비율이 높았다. Objectives : The authors compared the status of discharged schizophrenics between who are continuously followed and who are not in the treatment. Also we compared compliance factors among administered drug groups of the follow-up schizophrenics. Methods : First, we surveyed and analysed one hundred-four schizophrenics after discharge. Second, we analysed the questionnaires which were written by the forty-six follow-up patients who were asked about compliance factors. Results : There were no significant differences between patients who are continuously follow-up and who are not in the treatment on sex, age, educational level, marriage, occupation, religion, subtypes of schizophrenia, age of onset, duration of illness, admission rate, and complexity of drug administration methods Clozapine administered group had higher follow-up rate than that of other antipsychotics(rispendone and typical antipsychotics) administered groups among the discharged schizophrenics. Among the follow-up patients, there were significant differences between atypical antipsychotics patients and typical antipsychotics patients on economic difficulty, educational level, duration of illness, admission rate. There were no significant differences on the other of demographic and psychiatric characteristics. Conclusion : Clozapine administered group had higher follow-up rate than that of ther antipsychotics administered groups among the discharged schizophrenics.

열처리 조건이 시금치의 이화학적 특성 및 영양 조성에 미치는 효과

이지선, 황인국, 유선미, 민상기, 김광일, 조연지, 최미정 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.1

This study investigated the effect of thermal treatment (blanching) conditions on the physicochemical and nutritional properties of spinach. For thermal treatments, fresh spinach was treated by three blanching methods including boiled water, steam and pan frying treatments. At the varying time intervals of treatments, pH, color, shear force, proximate composition, organic acid content, peroxidase activity and microbial counts were evaluated. The pH of all treatments tended to increase with increasing blanching time, however, no significant differences among treatments were obtained. The shear force of spinach decreased with blanching time, particularly hot water treatment showed the rapid decrease in the shear force of spinach. The lightness of spinach showed similar pattern with shear force. For proximate compositions, the highest moisture content was found in hot water treatment, while crude protein and ash were highest in steam treatment. Due to the usage oil, pan frying treatment involved in the highest lipid content. The organic acid content treatment was in the order of hot water, pan frying and steam treatment. The thermal treatments attributed to low total plate count of spinach. In addition, thermophilic bacteria, coliform, mold and yeast were not detected in all thermal treatments. Peroxidase activity was lowered by applied thermal treatments. Based on the results, the best blanching condition for spinach was found in steam treatment for 60 s where the spinach showed the minimal changes in physicochemical and nutritional properties of spinach.

생성 요약 향상을 위한 가중치 문맥 벡터 기반 BART 모델

조성국(Sung-Guk Jo),온병원(Byung-Won On) 한국정보기술학회 2021 한국정보기술학회논문지 Vol.19 No.10

An abstractive summary is a short text containing only salient information from the original text. In our work, given an original text, the Extractor first classifies whether each sentence is salient or not. Then, in fine-tuning BART, by a weight, scaling the context vectors of the encoder corresponding to the salient sentences can give the effect of clustering by increasing the margin between two clusters - One contains salient sentences and the other non-salient ones. Consequently, our modified BART model can show high performance by learning these clustering patterns. Our experimental results show that BART using the proposed method improves up to 3% in ROUGE score and 0.2% in BERT score.

문맥 벡터 군집화를 통한 BART 모델의 생성 요약 향상 방안

조성국(Sung-Guk Jo),온병원(Byung-Won On) 한국정보기술학회 2021 Proceedings of KIIT Conference Vol.2021 No.11

생성 요약을 위한 사전학습된 시퀀스 투 시퀀스 모델의 기존 학습 방법은 원본 텍스트의 중요 문장과 중요하지 않은 문장을 고려하지 않는다. 본 논문에서는 추출기를 통해 원본 텍스트에서 중요한 문장과 그렇지 않은 문장에 대한 정보를 얻어내고, 이를 바탕으로 BART의 인코더 문맥 벡터를 군집화하는 방안을 제안한다. 그리고 제안 방안을 통해 중요 문장과 그렇지 않은 문장에 대한 패턴을 학습한 BART가 기존 방식보다 높은 성능을 보이는 것을 비교 실험을 통해 확인했다. The existing training method of a pre-trained sequence-to-sequence model for abstractive summarization does not consider salient and non-salient sentences in the original text. In this paper, we propose a method to obtain information about salient and non-salient sentences from the original text through an extractor, and to cluster BART"s encoder context vectors based on this information. In addition, it was confirmed through comparative experiments that BART, which learned patterns for salient and non-salient sentences through the proposed method, showed higher performance than the existing method.

Single-Stage Posterior Subtotal Corpectomy and Circumferential Reconstruction for the Treatment of Unstable Thoracolumbar Burst Fractures

Jo, Dae-Jean,Kim, Ki-Tack,Kim, Sung-Min,Lee, Sang-Hun,Cho, Myung-Guk,Seo, Eun-Min The Korean Neurosurgical Society 2016 Journal of Korean neurosurgical society Vol.59 No.2

Objective : To illustrate the technique of single-stage posterior subtotal corpectomy and circumferential reconstruction for the treatment of unstable thoracolumbar burst fractures and to evaluate the radiographical and clinical outcomes of patients treated using this technique. Methods : 16 consecutive patients with unstable thoracolumbar burst fractures were treated with single-stage posterior subtotal corpectomy and circumferential reconstruction. The mean patient age was 54.8 years. The mean follower up period was 25 months. Five patients suffered from T12 fractures, 10 from L1, 1 from L2. The segmental kyphosis, neurologic status, visual analogue scale for back pain was evaluated before surgery and at follow up. Results : The segmental kyphotic angle improved from 18.5 degrees before surgery to -9.2 degrees at the last follow up. The mean correction angle was 28.9 degrees. The mean surgical time was 255 minutes, and a mean intraoperative blood loss was 1073 mL. Intraoperative complications included two dural tears, and a superficial wound infection. There were no other severe complications. The mean visual analog scale of back pain decreased from a mean value of 6.6 to 2 at the last follow up. Conclusion : The single-stage posterior subtotal corpectomy and circumferential reconstruction achieved satisfactory kyphosis correction with direct visualization of the circumferentially decompressed spinal cord, as well as good fusion with less blood loss and complications. It is a safe and reliable surgical treatment option for unstable thoracolumbar burst fractures.

자궁경부의 선암종에서 Polymerase Chain Reaction에 의한 Human Papillomavirus DNA 16/18의 검색

이상숙,박남조,윤종국 대한병리학회 1995 Journal of Pathology and Translational Medicine Vol.29 No.4

The Incidence and Management of Dural Tears and Cerebrospinal Fluid Leakage during Corrective Osteotomy for Ankylosing Spondylitis with Kyphotic Deformity

Jo, Dae-Jean,Kim, Ki-Tack,Lee, Sang-Hun,Cho, Myung-Guk,Seo, Eun-Min The Korean Neurosurgical Society 2015 Journal of Korean neurosurgical society Vol.46 No.4

Objective : To present the incidence and management of dural tears and cerebrospinal fluid leakage during corrective osteotomy [Pedicle Subtraction Osteotomy (PSO) or Smith-Petersen Osteotomy (SPO)] for ankylosing spondylitis with kyphotic deformity. Methods : A retrospective study was performed for ankylosing spondylitis patients with fixed sagittal imbalance, who had undergone corrective osteotomy (PSO or SPO) at lumbar level. 87 patients were included in this study. 55 patients underwent PSO, 32 patients underwent SPO. The mean age of the patients at the time of surgery was 41.7 years (21-70 years). Of the 87 patients, 15 patients had intraoperative dural tears. Results : The overall incidence of dural tears was 17.2%. The incidence of dural tears during PSO was 20.0%, SPO was 12.5%. There was significant difference in the incidence of dural tears based on surgical procedures ( PSO vs. SPO) (p<0.05). The dural tears ranged in size from 12 to $221mm^2$. A nine of 15 patients had the relatively small dural tears, underwent direct repair via watertight closure. The remaining 6 patients had the large dural tears, consequently direct repair was impossible. The large dural tears were repaired with an on-lay graft of muscle, fascia or fat harvested from the adjacent operation site. All patients had a successful repair with no patient requiring reoperation for the cerebrospinal fluid leak. Conclusion : The overall incidence of dural tears during PSO or SPO for ankylosing spondylitis with kyphotic deformity was 17.2%. The risk factor of dural tears was complexity of surgery. All dural tears were repaired primarily using direct suture, muscle, fascia or fat graft.

Prebiotics/Probiotics Mixture Induced Changes in Cecal Microbiome and Intestinal Morphology Alleviated the Loperamide-Induced Constipation in Rat

Min Guk Kim,Kyungae Jo,Kyoungwon Cho,Sung Sun Park,Hyung Joo Suh,Ki-Bae Hong 한국축산식품학회 2021 한국축산식품학회지 Vol.41 No.3

The aim of this study was to investigate the effect of a mixture of multi-strain probiotics and prebiotics on loperamide-induced constipation in Sprague-Dawley rats. A multi-strain probiotics alone (loperamide-induced group with multi-strain probiotics mixture group; Lop-Pro) and a mixture of multi-strain probiotics and prebiotics (loperamide-induced group with multi-strain probiotics and prebiotics mixture group; Lop-Pro/Pre) were administered orally after inducing constipation. The fecal water content was significantly higher (by 42%) in the Lop-Pro/Pre group (33.5%) than in the loperamide-induced group (Lop) (23.7%) (p<0.05). The intestinal mucosal thickness, crypt cell area, and interstitial cells of Cajal area were significantly higher in the Lop-Pro/Pre group compared to the Lop group by 16.4%, 20.6%, and 42.3%, respectively. Additionally, the total short-chain fatty acid content was significantly increased in the Lop-Pro and Lop-Pro/Pre groups by 56.4% and 54.2%, respectively, compared with the Lop group. The Lop-Pro and Lop-Pro/Pre groups recovered loperamide-induced alteration in Bacteroidetes and Verrucomicrobia abundance among intestinal microbiota, whereas the Lop-Pro/Pre group recovered Akkermansia, Lactobacillus, Clostridium, Bacteroides, and Oscillibacter abundance. Moreover, the relative abundance of Oscillibacter and Clostridium was significantly different in the Lop-Pro/Pre group compared to the Lop group. Collectively, administration of synbiotics rather than multi-strain probiotics alone is effective in alleviating constipation.

스마트그리드 환경에서의 에너지 관리 및 리스크 기반 통합 전력계획

문국현(Guk-Hyun Moon),조형철(Hyung-Chul Jo),김영욱(Young-Wook Kim),주성관(Sung-Kwan Joo) 한국통신학회 2012 한국통신학회 학술대회논문집 Vol.2012 No.6

MMC-세라믹 적층배열 연구 및 모듈화를 통한 방호구조 설계

박상원(Sang Won Park),지정환(Jung Hwan Ji),조일국(Il Guk Jo),이민형(Minhyung Lee) 대한기계학회 2018 大韓機械學會論文集A Vol.42 No.8

LS-DYNA를 이용한 수치해석과 탄도충격시험을 통해, 압축강도가 높은 세라믹 타일을 낮은 밀도에 비해 높은 강도를 갖는 금속복합소재(MMC)로 감싸 전체적인 질량효율을 높이는 방호적층구조 배열연구를 수행하였다. SiC/A356, SiC/Al7075, B₄C/Al7075의 세 가지 금속복합소재를 사용한 적층배열에서 질량비에 따른 방호성능을 비교하여, 최적의 배열을 조사하였다. 또한 다중 피탄에 유효한 아머 시스템을 개발하기 위해 모듈형 세라믹 타일 구조에 대한 효과를 연구하였다. 세라믹 타일의 크랙으로 인해 주변부로 전파되는 방호성능의 저하를 방지하기 위해 세라믹 타일의 크기에 따른 방호성능의 감소정도를 조사하였다. 이를 방호구조 모듈화 설계 가이드라인으로 활용 가능할 것이다. A combined numerical analysis with LS-DYNA and ballistic impact test was carried out to develop an improved armor system by encapsuling high-strength ceramic tile with metal matrix composite (MMC) material. The MMC is a good candidate in terms of mass efficiency since it is lightweight but still shows high strength. In order to examine its protection performance, three MMCs (SiC/A356, SiC/Al7075, B₄C/Al7075) were tested in a laminated arrangement. In addition, the modular system was examined. This system is designed to prevent the degradation in protection performance due to crack propagation in multiple shot scenarios. To do this, several simulations were performed by changing the tile size in modularization.