비소성 준설토의 침강-압밀 거동 특성

박윤균,박병수,정길수,유남재 江原大學校 産業技術硏究所 2004 産業技術硏究 Vol.24 No.A

A series of column test with a silty marine soil mixed with Jumunjin Standard Sand were performed to investigate the characteristics of settling and consolidation of non-plastic dredged soils. Column tests were carried out by using the separable column to measure the grain size distribution of consolidated layer. Column tests were performed with changing the mixing ratio of Jumunjin Standard Sand to the silty marine soil, initial water content of slurry and initial height of slurry. Height of interface of slurry was monitored during tests and grain size distribution tests were carried out after finishing tests. Influencing factors on the particle segregation, eventually to the characteristics of settling and consolidation of non-plastic soil, were analyzed on the thesis of test results. As results of column tests, the mixing ratio of sand to the silty marine soil and the initial water content of slurry were known to affect the characteristics of settling and consolidation resulted in significant particle segregation of slurry. Initial height of slurry was found not to affect seriously to particle segregation.

구내방사선사진의 프랙탈 분석을 이용한 골다공증 예측

박금미,정연화,나경수 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.1

Purpose : The purpose of this study was to investigate whether the fractal dimension and radiographic image brightness of periapical radiograph were useful in predicting osteoporosis. Materials and Methods : Ninety-two postmenopausal women were classified as normal, osteopenia and osteoporosis group according to the bone mineral density of lumbar vertebrae and periapical radiographs of both mandibular molar areas were taken. The ROIs of 358 areas were selected at periapical and interdental areas and fractal dimension and radiographic image brightness were measured. Results : The fractal dimension in normal group was significantly higher than that in osteoporosis group at periapical ROI (P<0.05). The radiographic image brightness in normal group was higher than that in osteopenia and osteoporosis group. There was significant difference not only between normal and osteopenia group (P<0.05) but also within osteopenia and osteoporosis group (P<0.01) at periapical ROI. Significant difference was observed not only between normal and osteopenia group but also between normal and osteoporosis group at interdental ROI (P<0.01). Positive linear relationship was weakly shown at Pearson correlation analysis between fractal dimension and radiographic image brightness. BMD significantly correlated with fractal dimension at periapical ROI (P<0.01), and BMD and radiographic image brightness significantly correlated at both periapical and interdental ROIs (P<0.01). Conclusion : This study suggests that the fractal dimension and radiographic image brightness of periapical ROI may predict BMD.

인공위성 자료에 의한 홍수흔적분석의 타당성 검증에 관한 연구

박병욱,최윤수 안성산업대학교 1997 論文集 Vol.29 No.2

The objective of this paper is to evaluate methodology that uses satellite data for analysis of flood damaged area. We performed land cover classification using satellite data that were acquired at two weeks after the floodwater recession, and verified accuracy by comparison with the analyzed output to field survey results. The results show that analyzed output are corresponded with field survey very well. and also, some areas that had been missed in field survey were found. Therefore we can prove that the suggested method is more accurate and effective for mapping inundated areas of floodplains than field survey that would be held a few month later.

GLE의 영어 교과과정

박상수,정윤걸 釜山外國語大學校 語文學硏究所 1999 外大語文論集 Vol.14 No.-

The students who study in GLE(=Globalized and Localized experts) program must have a good command of English, especially in speaking and listening when they complete whole courses. In order to achieve this aim successfully the English curriculum for the GLE should be organized systematically as well as the intellectual faculties of the students, teaching methods and the beginning age of English teaming should be considered seriously We researched the learning theories of a foreign language and the four functional skills of language and proposed a few hints that the students in the GLE keep in mind while they learn English. The results obtained from this paper are summarized as follows: 1. The students who study in the GLE can effectively improve the ability of the command of English not through the way of language acquisition but through the way of language learning because they began to learn English at middle school days. In fact at the age of over 12 or 13 the language acquisition faculty has grown and consequently the value of linguistic parameters has already been set. 2. When the students in the GLE learn English, the emphasis should be laid on the improvement of speaking and listening ability primarily and then reading and writing ability should be developed. 3. It is necessary that the students understand the British and American social and cultural properties fully. As a particular language is the product of the social and cultural life of a certain language group, language learning always includes the understanding of the social and cultural properties of the people who use the target language.

Headspace Sampler와 Gas Chromatography를 이용한 방향족 화합물의 무차원 헨리 상수 측정

박수진,임화윤,박소진 한국화학공학회 2004 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.42 No.1

방향족화합물의 무차원 헨리상수(Air/Water 분배계수 : K_(aw))를 headspace sampler(HSS)와 gas chromatography(GC)를 이용하여 318.15-355.15 K 온도 범위에서 온도를 변화시키며 측정하였으며, 이 방법으로 시료와 평형 및 채취, 분석 과정에 있어서 용질의 휘발로 인한 오차와 수작업에 의한 측정 오차를 최소한으로 줄이고자 하였다. HSS내 평형용기의 기상과 액상조성은 GC의 피크면적과 물질수지 식으로부터 계산하였으며, 이 관계식을 이용하여 benzene을 비롯한 몇 개의 방향족 화합물의 무차원 헨리상수를 온도별로 측정하였고 문헌값과 비교하여 방법의 신뢰성을 확인하였다. 또한 온도와 무차원 헨리상수의 함수관계를 통해 온도에 따른 무차원 헨리상수 값을 유추하는 방법의 가능성을 살펴보았다. Dimensionless Henry's law constants of aromatic compounds in water were measured at various temperatures between 318.15-355.15K using a headspace autosampler with a gas chromatography. This measuring system prevent, sample losses due to volatilization from equilibration, sampling, and chemical concentration analysis by a high precision headspace sampler and gives relatively accurate results. Dimensionless Henry's law constant is calculated by thermodynamic relation and the mass balance with gas chromatographic peak area. Different equilibrium concentration in gas phase was made by using different gas-liquid volume ratio in sample vial. The temperature dependence of dimensionless Henry's law constant was correlated with the classical van't Hoff equation as a function of temperature. The extrapolated data at 298.15K from correlated equation were compared with available literature data in order to test this method.

동일한 시료에 대한 국내 기관간의 STR 분석결과 비교 : STR 유전자좌 분석법의 표준화 설정을 위하여

박종태,신경진,양윤석,우광만,이숭덕,이승환,이정빈,정연보,조승희,한길로,한면수,홍승범 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

This paper described a collaborative exercise intended to see what kinds of short tandem repeat (STR) loci are used in different DNA typing laboratories in Korea and to compare their results for the demonstration whether uniformity of DNA profiling results from different laboratory could be achieved in Korea Laboratories were asked to test five tissue DNAs using methods routinely used in each laboratory and to report the results to the coordinating laboratory. The exercise demonstrated that each laboratory was using different STR loci for the typing with different STR numbers,2 VNTRS,36 STRs and amelogenin in total, and the direct comparison of the results from all the laboratory for the 18 loci could not be done as only one laboratory submitted typing results. Among 21 loci for which several laboratories submitted typing results, results for 14 loci were the same and results for the other 7 loci were different depending on the participating laboratory. D1S80, F13A01, D16S539, D21S11, D18S51, D3S1744 were the loci with different typing results. Even in the cases where commercial kits were used, the results were not the same depending on the machines used, that is the capillary electrophoresis or the gel based electrophoresis. The reason for the different results, points about the standardization of the methods arid the profiling data were described.

藥鍼用蜂毒液이 黑色腫細胞에 미치는 抗癌效果에 對한 分子生物學的 硏究

朴贊烈,南相水,金昌煥,李栽東,姜成吉,李潤浩,安秉哲 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

To study anti-cancer effect and molecular biological mechanism of bee venom for aqua-acupuncture, the effects of bee venom on cell viability, apoptosis, and cell cycle were analyzed using MTT assay, tryphan blue assay, [3H]thymidnine release assay, flow cytometric analysis, activity of caspase-3 protease activity assay, and immunocytometric analysis of PCNA. To explore whether anti-cancer effects of bee venom are associated with the transcriptional control of gene expression, quantitative RT-PCR analysis of apoptosis- and cell cycle-related genes was performed. The obtained results are summarized as follows: 1.The MTT assay demonstrated that cell viability was decreased by bee venom in a dose-dependant manner. 2.Significant induction of apoptosis was identified using tryphan blue assay. [³H]thymidine release assay, and flow cytometric analysis of sub G₁fraction. 3.In analysis of caspase-3 protease activity, the activity had increased significantly, in a dose-dependant manner. 4.Quantitative RT-PCR analysis of the apoptosis-related genes showed that Bcl-2 and Bcl-X□ were down-regulated whereas Bax was up-regulated by bee venom treatment. 5.In flow cytometric analysis of cell cycle and immunocytometric analysis of PCNA expression, cell numbers of G₁phase was increased by a dose-dependant manner. 6.In quantitative RT-PCR analysis of the cell cycle-related genes, p21, p27, and p57 were increased, while Cyclin D1, CDK4, c-Myc, c-Fos, and Histone H3 were decreased. In contrast, there were no remarkable changes in expression levels of CDC2 and c-Jun.

Effect of Ionizing Radiation on Rat Tissue: Proteomic and Biochemical Analysis

Park*, Eui‐,Chul,Yoon, Jong‐,Bok,Seong*, Jin‐,Sil,Choi, Kyoung‐,Soo,Kong, Eung‐,Sik,Kim, Yun‐,Jeong,Park, Young‐,Mee,Park, Eun‐,Mi Taylor Francis 2006 Preparative biochemistry & biotechnology Vol.36 No.1

<P>Reactive oxygen species (ROS), generated by ionizing radiation, has been implicated in its effect on living tissues. We confirmed the changes in the oxidative stress markers upon irradiation. We characterized the changes in the proteome profile in rat liver after administering irradiation, and the affected proteins were identified by MALDI-TOF-MS and ESI-MS/MS. The identified proteins represent diverse sets of proteins participating in the cellular metabolism. Our results demonstrated that proteomics analysis is a useful method for characterization of a global proteome change caused by ionizing radiation to unravel the molecular mechanisms involved in the cellular responses to ionizing radiation.</P>

가르친다는 것(Teaching)의 세 가지 접근

박수연 이화여자대학교 교육과학연구소 2001 교육과학연구 Vol.32 No.1

이 논문에서는 가르친다는 것(교수:teaching)에 대한 세 가지 접근을 가지고 교사의 교수 역할을 이론적으로 분석하고 이에 따른 비평을 하였다.가르친다는 것을 (1) 관리자로서의 접근; (2) 치료자로서의 접근; 그리고 (3) 자유주의자로서의 접근으로 설명을 하였다.이 접근들은 각각 교사를 (1) 가장 효과적인 기술을 이용하여 학생들의 학습이 이루어지게 하는 사람으로; (2) 학생들을 개인적으로 자라게 하고 자기실현, 자기수용에 도달하게 하는 인정 있는 사람으로; 그리고 (3) 학생들을 무지와 편견으로부터 자유롭게 하고, 자율적이며 합리적이며 도덕적으로 발전시켜 주는 사람으로 보게 한다.이 세 가지 접근은 가르친다는 것이 무엇인가라는 개념 이해에 도움을 주며 개념 이해는 실제 상황에서 개인적, 교육적 문제 그리고 윤리적 문제를 해결하는 데 응용될 수 있는 중요한 역할을 한다. 이 연구는 실제 가르치는 위치에서 이 접근들을 유용하게 적용할 수 있는지에 대한 논의도 시도하였다.현실적으로 교사는 어떤 때에는 관리자가 될 수 있고 다른 때에는 치료자가 될 수 있으며, 또 다른 때에는 자유주의자가 될 수 있다는 것이다.사실상, 교수 상황이 그렇게 해야 될 수밖에 없을 때도 있게 된다는 것이다.학생들이 학교에서의 경험으로부터 가능한 한 가장 많이 얻을 수 있게 하기 위하여 이 세 가지 접근을 어느 정도 통합해야 할 것이다. This article analyzes teaching on the basis of three new approaches.The three approaches on which this theoretical analyzation is based include the executive approach, the therapist approach and the liberationist approach.The executive approach views the teacher as an executor, a person charged with bringing about certain learnings, using the best skills and techniques available.Contemporary research on the effects of teaching and learning is very important to this approach.The therapist approach views the teacher as an empathetic person charged with helping individuals grow personally and reach a high level of self-actualization, understanding and acceptance.Humanistic psychology and existential philosophy underwrite this view, which focuses on students' developing their own selves as authentic persons through personally meaningful educational experiences.The liberationist approach views the teacher as a liberator, a freer of the individual's mind and a developer of well-rounded, autonomous, rational and moral human beings.The classical idea of a liberal education underwrites the contemporary mainstream version of this approach. This conceptual understanding is significant in that it stimulates teachers to think about ways to conceive their teaching role.How teachers conceive of their teaching role has a great effect on what they do as a teacher.What a teacher thinks teaching is determines what kind of teacher he is going to be.Conceptual understanding also helps teachers when they make practical applications and face personal, pedagogical and moral educational issues. This study also discusses how teachers can apply the theoretical conceptions in practical situations in teaching.A teacher can, for example, be an executive at times, a therapist at others, a liberationist at still others.In fact, there seem to be situations in teaching that call on a teacher to do that.This study suggests that in order to let students gain to the fullest extent possible from their experiences at school, teachers must try to integrate these three approaches to certain degrees.

특수 언어발달 장애 환아의 임상 및음향음성학적 특성연구

김연희,박세훈,신용일,김찬양,김현기,김정수 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.1