[논문]예비 과학교사의 방사선에 대한 개념 및 인식조사

강연수,안정근 釜山大學校 師範大學 科學敎育硏究所 2010 科學敎育硏究報 Vol.37 No.-

A Survey of Pre-service Science Teacher's Perception and Conceptions of Radiation

정신병원 간호사의 공정성 지각과 조직몰입이 이직의도에 미치는 영향

정수미,민순,강명근,류소연,박종,김기순 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Objectives: The purpose of this study was to identify the influence of equality perception and organizational commitment on turnover intention of jobs among psychiatric hospital nurses. Method: Data were collected by questionnaire survey among 158 nurses working in 10 psychiatric hospitals from August 1st to September 30th. 2004. Results: The degree of turnover intention of jobs was significantly different by marital status, religion, qualification of psychiatric specialized nursing, monthly income and the location of hospitals. The correlation analysis showed that the turnover intention of jobs decreased as the equality perception and the organizational commitment increased. The hierachical multiple regression analysis showed that significantly related variables with turnover intention of jobs were religion, monthly income, equality perception and organizational commitment. The model explanation power was 53.1%. Conclusion: Because the equality perception explained 53.1% of variance of turnover intention among psychiatric nurses and organizational commitment was related with the turnover intention of nurses at psychiatric hospitals, activation strategy of organization must include the promotion strategy of equality perception and organizational commitment to decrease turnover intention of jobs among nurses.

한글과 한자를 이용한 스트룹 과제에서의 간섭 효과

조증열,유경순,김길님,이수란 慶南大學校 人文科學硏究所 1998 人文論叢 Vol.11 No.-

Comparative double blind test에 의한 抗아메바劑 Ro7-0207(Tiberal), Metronidazole 및 Dehydroemetine의 治效成績의 比較

李午政,全鍾暉,朴弼遠,朴壽泳 대한감염학회 1974 감염 Vol.6 No.1

Introduction New and better substances are still being sought for the treatment of amoebiasis. The aim of this trial is to assess the effectiveness and tolerance of Tiberal and oral dehydroemetine in patients with oligosymptomatic (or mild) intestinal amoebiasis comparing with that of metronidazole which are known to be an active amoebicide. Selection of cases. Lately, classical symptomatic amoebiasis accompanying mucus-bloody stool and tenesmus could be seldom experienced at urban areas in this country. At here the majority of intestinal amebiasis is manifested by loose stools containing mucus, pus or blood (rare), and also by a rapid response to antibioties, but with frequent episods of recurrence caused by diet-failure or alcohol drinking. Among 187 cases of mild enterocolitis which were suspected as being mild intestinal amoebiasis clinically, authors selected amoeba-positive 60 cases and additional 7 cases which were included later in this clinical trial study. The 7 drop-outs in the original study were replaced by these additional 7 cases. The clinical trials were carried out at the St. Mary's Hospital, Catholic Medical College, Seoul, Republic of Korea. During 12 month (April 25, 1973-May 17, 1974), we treated 60 cases of so-called oligosymptomatic amoebiasis with above mentioned three amoebicides. 60 ambulatory cases suffering from mild GI troubles were admitted into the trial (liable to recurrent diarrhoeal stools including mucus, or pus with tenesmus, and also to lower abdominal discomfort of mild pain) those were suspected clinically as having intestinal amoebiasis with carriers of E. histolytica (trophozoits and/or cysts in the feces). Oligosymptomatic amoebiasis group, in this clinical trial study, consisted of 34 males and 26 females ranging from 17 to 62 years of age. All were adolescents or adults and their age distribution was shown in Table 1. Methodology on this clinical trials. We have carried out so-called the comparative double blind trials with Tiberal versus Metronidazole versus oral Dehydroemetine in symptomatic amoebiasis of mild grade. The trial drugs were given also without the knowledge of either the one who gave it or the one who got it in this comparative double blind study. Both (drug examiner) doctors and (drug examined) patients have had no knowledge of each drug. Pharmacist responded to doctor's prescription with code numbers. After the completion of the study the exact name of a drug were publically drawn from the code numbers and the purpose of double blind study was attained. In this study an arrangement for a drug administration schedule was set by as pharmacist exclusively. 60 patients were assigned to one of the three drugs by proper randomization so that 20 patients received tiberal and 20 metronidazole and 20 oral dehydroemetine. After the trial, code numbers of the drugs were identified; nos. 1, 6, 10, 14, 19, 23, 25, 27, 28, 29, 33, 34, 35, 36, 44, 45, 47, 51, 53, and 54 were tiberal; 8, 9, 11, 12, 13, 15, 16, 18, 20, 22, 32, 39, 41, 48, 49, 50, 52, 55, 56, and 57 were metronidazole, and nos. 2, 3, 4, 5, 7, 17, 21, 24, 26, 30, 31, 37, 38, 40, 42, 43, 46, 58, 59 and 60 were oral dehydroemetine. Evaluation The therapeutic effects were assessed by the clinical evolution and by stool parasitology (direct examination and concentration method) performed on day 3 and 6 on treatment, and then at the end of treatment (8-10 day) and one month after the initial treatment. This made a total 4 to 5 parasitological examination per patient, including one examination required for diagnosis prior to treatment. At the same time aspect and consistency of the stool were registered. The effect of the drugs on other protozoa found in the stools were also reported. The tolerance were assessed by clinical findings and laboratory studies made in limited cases at least before and after treatment unless otherwise stated. Blood count, BUN, Alkaline phosphatase, SGP, TECG and urinalysis were performed as laboratory controls. Authors have established following evaluation criteria for this clinical study. Radical cure: free of symptoms with no vegetative or cystic forms of E. histolytica in stool on 3 successive tests. Biological cure: no cystic forms of E. histolytica in stool on 3 successive tests, but persistence of some intestinal disturbances. Relapse: apparent cure or improvement (with negative of 3 successive tests) followed by recurrence with vegetative amoeba on direct smear within 30 days. (re-infection may be included) Failure: the trophozoites or cystic form of E. histolytica has persisted for treatment periods, with some intestinal troubles. Methods of treatment and parasitologic examination In each group one third of the patients received 2 capsnles of 250mg. Tiberal thrice daily for 7 days, one third received 2 tablets of 250 mgmetronidazole thrice daily for 7 days, and one third received 2 tablets of 10 mgdehydroemetine thrice daily for 7 days as the only specific drug. No associated drugs were given together for symptomatic relief in all cases. The reason why fixed 7 days dose were delivered to every cases was based on convenience of stool examination and equalizing the number of days for therapy. The therapeutic drugs were delivered usually for 2 days dose (1st prescription), 3 days dose and 2 days dose (3rd prescription) successively, therefore stool examination had been done on 3rd, 6th and 8-10th day of therapy. Clinical results In oligosymptomatic amoebiasis, 20 cases each were treated with doses of 1,500mg/day of Tiberal and metronidozole for 7 days respectively, and 20 cases were treated with doses of 60mg/day of dehydroemetine for 7 days. The total doses administered were 10,5g, 10,5g, and 420mg respectively in a period of 7 days. Among tiberal group 19 cases were found to be negative after therapy whereas there was 1 with parasitological failure. The clinical effect was fast in 95% of the cases. Effective cure was achieved in 17 whereas symptoms persist in 3 patients among 20 cases. There were 1 failure and 2 late relapse. Comparing data of therapeutic results with that of metronidazole and dehydroemetine were shown in Table 2 & 3. Table 3 shows the negativity rate of trophozoits or cystic form of E. histolytica in stools according to therapeutic periods of trial drugs received. The data would indicated that 5 days dose could not be enough to eradicate the parasites even in the susceptible cases. The result data of clinical improvement and clearance of E. histolytica in patient stool among drug trial groups were shown in Table 4. The cases treated with Tiberal showed no clinical signs on average 4,9 days and negative amoeba in stool on average 4,1 days of therapeutic periods, comparing with on average 5,8 days and 4,1 days in metronidazole-treated group, and on average 6,3 days and average 4,5 days in dehydroemetine-treated group respectively. Authors put in order the therapeutic procedures and their result of failed or relapsed cases with unplanned measures in table 5. These data could be obtained after the completion of the comparative double blind study by the code numbers which were publically drawn afterwards. These therapeutic procedures had been made just incidentally, not by prior plan. 2 cases, 4 cases and 3 cases could get finally effective cure by doubling doses of 7 days course of Tiberal, metronidazole and dehydroemetine respectively. 1 failed case treated with dehydroemetine and 1 another failed case with tiberal could get effective cure by additionally receiving metronidazole and dehydroemetine respectively. 2 failed cases treated with metronidazole could be cleared of parasites by adding tiberal effectively. Adverse reactions were noticed in 20% each of the patients treated with Tiberal and also with metronidazole, and 25% of those treated with dehydroemetine. They were all transient and never severe. There was not a single case who was discontinued on therapy owing to its side-effects. No significant change of laboratory data was noticed by the administration of trial drugs. Brief summary Tiberal, metronidazole and dehydroemetine (oral) were all recognized as highly efficacious anti-amoebic drugs in this clinical studies. On account of following standpoints 1) clearance of parasites in stool 2) clinical symptomatic relieving 3) drug tolerance 4) rate of relapse and failure 5) side-effects, Tiberal could be received much more recognition than metronidazole and dehydroemetine did. P. S. Authors has experienced other 10 cases of amoebiasis among in patients (5 moderate severe intestinal amoebiasis, 4 liver abscesses and 1 lung abscess) treated with Tiberal and metronidazole with excellent therapeutic results, without any sequelae or relapse.

우측 귓바퀴 뒷면에 발생한 혈관평활근종 1예

박수정,송현정,김주용,김창덕,김창욱,이규석 대한피부과학회 2006 大韓皮膚科學會誌 Vol.44 No.4

갑상선 세포에서 전사보조활성인자인 CBP와 CIITA의 인터페론-감마 활성 부위에 대한 조절 : CBP and CIITA on GAS(Interferon- γ Activated Site)-Mediated Transcription in Thyroid Cells

채수흥,홍우정,김군순,조영석,김도희,김현진,구본정,송민호,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 2001 충남의대잡지 Vol.28 No.1

Background : In the previous stuides, we identified that the interferon-r activated sequence (GAS) in the 5-flanking region of rat ICAM-1 gene is major element for interferon-r-inducible expression of the gene in rat thyroid cells, FRTL-5. We here, investigated the role of transcriptional coactivators, CBP(CREB binding protein) and CⅡTA (class Ⅱ transactivator) in the modulation of the activity of GAS which could interacts with signal transducers and activators of transcription-1 and 3 (STAT1 and STAT3). Methods : The expression of CBP RNA and protein were quantitated in FRTL-5 after stimulation with interferon-r (IFN-r), thyroid stimulating hormone (TSH), forskolin and methimazole. Direct association of CBP with STAT were analyzed by immunoprecipitation. The transcriptional roles of CBP and CⅡTA in the regulation of GAS were assessed by the cotransfection with their expression vectors with reporters; 5-deletion constructs of rat ICAM-1 promoter or 8xGAS-luc constructs, into FRTL-5 thyroid cells. Results : The level of CBP RNA and protein were not changed by the treatment with TSH, IFN-r, forskolin and methimazole in FRTL-5, FRT and BRL liver cells. The CBP could be directly associated with STAT1. Furthermore, the overexpression of CBP significantly increases the both promoter activities; rat ICAM-1 gene promoter which has GAS element and 8xGAS-luc cassette constructs. However, the cotransfection of CⅡTA decreased the constitutive and CBP-mediated transactivation of rat ICAM-1 promoter and 8xGAS-luc cassette constructs. Conclusion : We identified that the two tanscriptional coactivators; CBP and CⅡTA has differential roles in the regulation of transcriptional activity of GAS drived promoter. CBP increases the GAS activity through the direct binding with STAT1, but CⅡTA inhibited the CBP-mediated transactivation of GAS activity.

Richard Meier 건축에서 기계미학의 전개에 관한 연구

鄭鎭洙,裵政煥 영남대학교 공업기술연구소 1999 工業技術硏究所論文集 Vol.27 No.2

Richard Meier, American architect, is a new successor of Modernism. He works in not only America but also Europe and Asia and becomes an influential architect in his field. Although he has his own original style, he is somewhat influenced by Le Corbusier, master of Modernism, in his works. Le Cobusier's machinery aesthetics means more than just ideology to Meier. He actually tries to represent master's machinery aesthetics in his works through formal imitation, especially in the motive of ship. In addition, the constitution of plan and mass which is established on the basic of early pure geometry represents the purification of molding language and combination of reason and sense as the form of three dimension which Le Corbusier tries to come true through Purism painting. In this way, Meier can extract something new from Le Corbusier's ideology about Modemism and show his architecture which is welcomed by everyone.

개 心臟 形質膜의 燐酸化에 關한 硏究

李正秀 대구산업정보대학 1997 논문집 Vol.11 No.2

Dog cardiac sarcolemma was phosphorylated by (γ^(32)p) ATP in the presence of exogenous protoin kinase and cyclic AMP, and the major phosphorylated bands had apparent molecular weights of 22,000 and 12,000. The phosphorylated of sarcolemma was slightly stimulated by exogenous cyclic AMP and inhibited about 30% by protein kinase inhibited, but not affected by exogenous protein kinase, suggesting the presence of endogenous protein kinase activity. However, the denatured sarcolemmal phosphorylation was absolutely dependent on the exogenous cyclic AMP with 30% of phosphate incorporation of that of fresh sarcolemma. The phosphotylation of denatured sarcolemma and histone by cyclic AMP-dependent protein kinase was completely inhibited by protein kinase inhibiter. The high level of the phosphorylation of histone by sarcolsmma without exogenous cyclic AMP and protein kinase was also inhibited by protein kinase inhibiter. The phosphorylated products were hydroxylamine insensitive which indicated the absence of the phosphate-incorporation of acylphosphate type. These results suggest that cardiac sarcolemmal protein contains endogenous protein kinase activity and sarcolemmal phosphorylation by cyclic AMP-dependent protein kinase occurred mainly on 22,000 and 12,000 dalton protein.

완선에 대한 항진균제(clotrimazole) 단독 및 스테로이드가 첨가된 복합체(Triamcinolone acetonide and Hydrocortisone)의 치료효과에 관한 비교 연구

이증훈,서우영,김기홍,최종수 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

Although the combination products of antifungal agents and corticosteroids are often used in the treatment of superficial fungal infections, their usefulness is not settled. The combined corticosteroids may promote the spread of fungi. On the other hand, they can bring rapid relief from signs and symptoms and increase the local concentrations of the antifungal agents in the skin due to the vasoconstrictive effect. This study was performed to compare an antifungal agent with its combination products with corticosteroids in the treatment of tinea cruris. Seventy-four patients with tinea cruris, aged 18-26 years, were admitted to the study. All ere soldiers living in the same conditions. Sixty patients completed 2 weeks of therapy : clotrimazole, 19 ; combination with trimacinolone acetonide, 28; combination with hydrocortisone, 13. All treatments almost completely improved the lesions at the end of 2-week period. No specific treatment was significantly better. After 4 weeks the relapse rate was highest in the group treated with clotrimazole combined with triamcinolone acetonide (75%), compared with clotrimazone alone (47%) or its combination with hydrocortisone (50%), but not significant statistically (p<0.05).

평판의 방사효율 특성에 관한 연구

김정태,강준수 弘益大學校 科學技術硏究所 1997 科學技術硏究論文集 Vol.8 No.-

It is very important to understand the vibration and noise characteristics of a structure to develope quiet machines and lessen their noise. In this paper, the vibration and sound radiation characteristics of a simple plate have been investigated using numerical technique. Three parameters that play important role in determining plate vibration and sound radiation characteristics have been considered : driving point mobility for structural vibration analysis, estimation of modal densities, and sound radiation efficiency of the plate. Estimation of modal density and driving point mobility based on statistical energy analysis(SEA) approach the theoritical values, especially for high frequency band with high modal density. Rediation efficiency for the simple plate shows very low values in low frequency band below the critical frequency and approaches the theoritical value in high frequency over the critical frequency.