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      • KCI등재후보

        Hepatic Cirrhosis Occurring in a Young Woodchuck(Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus(WHV)

        Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

        Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea

      • 分散 데이타베이스의 效率的인 質疑語의 처리

        權寧淡,金重秀,金正洪 嶺南大學校附設 基礎科學硏究所 1988 基礎科學硏究 Vol.8 No.-

        The efficient query processing is of im,portance ina distributed database management system. For a class of simple queries, it is possible to design optimization algorithm that will derive optimal distribution strategies. In this paper, a query <Extentended Simple Query> that is extension of simple query is defined. It is not necessary to reduce data transmission cost and to fully eliminate relations in a result site. Efficient algorithm for ESQ that considers semijonin operation sequences is presented.

      • C-means 알고리즘을 이용한 마이크로 엔드밀의 상태 감시

        권동희,정연식,강익수,김전하,김정석 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

        Recently, the advanced industries using micro parts are rapidly growing. Micro end milling is one of the prominent technology that has wide spectrum of application field ranging from macro to micro parts. Also, the method of micro-grooving using micro end milling is used widely owing to many merit, but has problems of precision and quality of products due to tool wear and tool fracture. This study deals with condition monitoring using acoustic emission(AE) signal in the micro-grooving. First, the feature extraction of AE signal directly related to machining process is executed. Then, the distinctive micro end mill state according to the each tool condition is classified by using the fuzzy C-means algorithm, which is one of the methods to recognize data patterns. These result is effective monitoring method of micro end mill state by the AE sensing techniques which can be expected to be applicable to micro machining processes in the future.

      • Drosera rotundifolia와 D. spatulata의 조직배양시 식물체 재생에 미치는 몇가지 영향

        권수정,김학현,이철희 충북대학교 첨단원예기술개발연구센터 2000 연구보고서 Vol.5 No.-

        Drosera spatulata는 영양분의 요구도가 낮아 1/2MS배지에서 가장 많은 식물체가 재생되었다. 대부분의 Drosera속 식물들은 식물체의 재생과 생장에 질소원의 요구도가 낮아 D. spatulata와 D. rotundifolia의 경우 MS배지의 1/4배에서 가장 많은 식물체가 재생되었다. 적정 sucrose의 농도는 식물의 종마다 달라 D. spatulata의 경우 4%에서 D. rotundifolia는 1%에서 무처리구에 비해 많은 식물체의 재생을 보였다. 대부분 활성탄은 식물체의 재생에 효과적이었으나 뿌리의 형성은 억제되는 경향이었다. D. spatulata는 0.05%에서, D. rotundifolia는 0.01%에서 가장 많은 식물체 재생을 보였다. 식물체 재생은 D. spatulata는 0.6%의 agar를 첨가한 배지에서 D. rotundifolia는 액체배지에서 가장 효과적이었다. pH 실험의 결과 D. spatulata는 pH 4.5에서 가장 많은 식물체 재생을 보였다. The study was conducted to fine out the effect of Drosera species showed generally low nutrient requirement, the highest shoot production was obtained with 1/2 strength of MS medium for D. spatulata than with any other strength of MS medium tested. The nitrogen requirement of Drosera species were also relatively low. The maximum shoot regeneration was achieved when cultured in 1/4 strength of nitrogen contained MS medium. The optimum sucrose concentration for each species was different, such as 4% for D. spatulata; 1% for D. rotundifolia. In general, activated charcoal had positive effect on shoot proliferation, but had negative effect on root formation of Drosera species. The best shoot regeneration was achieved on MS medium containing 0.05% activated charcoal for D. spatulata, 0.01% for D. rotundifolia. Shoot regeneration of Drosera rotundifolia was better in MS liquid medium and D. spatulata showing best results on 0.6% agar. The maximal shoot proliferation was achieved on the media adjusted to pH 4.5 for D. spatulata respectively.

      • KCI등재

        [18F]FDG PET을 이용한 강박증 환자에서 뇌 포도당 대사의 이상에 관한 연구

        권준수,이동우,이재성,최정임,이동수,정준기,조맹제,이명철,류인균 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

        연구목적: 강박증에 대한 기능적 뇌영상 연구들에서 강박증 환자들의 안와전두엽과 미상핵의 대사율 증가 소견이 비교적 일과되게 발표되어 왔으며, 전두-피질하 회로의 이상이라는 이론이 수립되기도 하였다. 그러나 기존의 연구들은 강박증의 유병기간에 따른 구분없이 시행된 연구였고, 영상분석 방법에 있어서도 관심영역 방법을 이용했다는 한계를 지니고 있다. 본 연구의 목적은 첫째, 강박증의 유병기간에 따라 환자군을 구분하여 PET 영상소견을 분석함으로써 유병 기간에 따른 차이가 있는지를 조사하였으며, 둘째, 강바증 환자의 포도당 양전자방출 단층촬영(18-Fluor-deoxyglucose Positron Emission Tomography : FDG-PET) 영상분석에 통계적 매개변수 지도법(Statistical Parametric Mapping : SPM)을 이용함으로써 강박증의 병인기전 및 강박증상과 뇌기능 간의 관계를 명확히 규명하고자 하였다. 방법: 구조적 면담도구(Structured clinical interview for DSM-IV : SCID-IV)를 적용하여 진단된 12명의 강박증 환자들과 10명의 정상 대조군에 대해 FDG-PET을 촬영하여 SPM으로 분석하였다. PET 촬영 전 적어도 4주 동안에는 약물복용을 하지 않은 상태였다. 결과: 1) 환자군과 대조군의 비교 : 강박증 환자군은 대조군에 비해 양측 두정 영역의 대사율이 유의하게 감소되어 있었으며(P<0.01). 대사증가를 보인 영역은 없었다. 강박증의 유병기간이 10년 이상인 만성강박증 환자 4명은 양측 안와전두엽에서 유의한 대사증가 소견을 보였으며(P<0.01), 양측 두정영역에서 유의한 대사감소 소견을 보였다 (P<0.01), 유병기간이 10년 이하인 환자에서는 전체 환자군의 분석에서와 마찬가지로 대조군에 비해 유의한 대사증가 소견을 보인 영역은 없었으며, 양측 두정엽 부위에서 유 의한 대사 감소 소견을 보였다.(P<0.01). 2) 강박증상의 심각도와의 상관관계 분석 : 우측 두정엽의 대사율은 강박장애 척도 점수와 유의한 음의 상관관계를 보였으며(p<0.01), 양측 시상 영역의 대사율은 예일-브라운 강박장애 척도의 강박장애척도 점수와 유의한 양의 상관관계(p<0.01)를 보였다. 결론: 본 연구는 결과는 기존의 연구들에서 보고된 안와전두엽의 대사 증가 소견이 강박증의 만성화로 인해 나타나는 2차적 장애이며, 두정엽의 대사 저하가 보다 1차적인 장애일 가능성을 시사한다. Baxter가 수립한 전두-피질하 회로 이론은 두정엽의 이상을 포함하는 전두-두정엽 복합체 이론으로 확장되어야 할 것이다. Objectives: Functional imaging studies on obsessive-compulsive disorder(OCD) subjects have repeatedly reported increased metabolism in orbitofrontal lobes and caudate nucleus, resulting in the "frontal-subcortical" circuit abnormality theory. Limitations of the previous studies to date include little consideration for the duration of illness, and the use of regions of interest methods, as an image analysis method. Our study objectives are 1) to include the duration of illness as an important study variable, and 2) to use Statistical Parametric Mapping(SPM) method in order to tap relations between the brain function and the psychopathology and symptoms of OCD. Methods: The [18] fluorodeoxyglucose positron emission tomography(FDG-PET) scans of OCD subjects and normal comparison subjects, as diagnosed by the Structured Clinical Interview for DSM-IV(SCID-IV), were analyzed using SPM. Results: 1) Comparison of OCD and control groups : OCD subjects had significantly decreased metabolism in both parietal lobes and didn't have any areas of increased metabolism in comparison to comparison subjects(p.<0.01). four OCD subjects with the illness duration of 10 years or longer, had significantly increased metabolism in both orbitofrontal lobes<p<0.01). OCD subjects whose illness duration is shorter than 10 years didn't have any areas of increased metabolism and had significantly decreased parietal lobe metabolism, as in the analyses of all subjects(p<0.01). 2) Correlation analysis between areas and symptom severity : Metabolism of both thalamic sreas showed significant positive correlation with Yale-Brown Obsessive-Compulsive Scale(Y-BOCS) scores(p<0.01). Metabolism of right parietal area showed significant negative corre lation with Y-BOCS scores(p<0.01). Conclusions: The current findings suggest that the increased metabolism in orbitofrontal lobe, previously rported, may be a secondary phenomenon due to the extended illness dur- ation and that decreased metabolism in the parietal lobes are primary abnormality in OCD subjects. Thus Baxter's fronto-subcortical circuit theory should be extended into "fronto-pari-etal" complex theory, which includes the parietal lobes.

      • KCI등재
      • KCI등재

        2단계 발효에 의한 포도식초와 재래식 포도식초의 품질 비교

        정용진,이명희,서권일,김주남,이용수 동아시아식생활학회 1998 동아시아식생활학회지 Vol.8 No.4

        Grape vinegar(A) and grape onion vinegar(B) added (3% of onion juice) were produced through two stages of fermentation(alcohol fermentation and acetic acid fermentation) to increase the grape's use. Grape wine which contained 5.6% alcohol was produced on the 3rd day of first stage. Then through the second stages, grape vinegar, of which total acidity was 5.37% was produced. The quality of (A) and (B) which was produced through the two stages of fermentation was compared with the traditional grape vinegar(C,D) in the market. The content of sugar in (D) was a little higher such as 5.4 °Brix than others. That of (A) and (B) was 5.13, 4.98 °Brix respectively. The content of remaining alcohol in (C) was high such as 0.23% comparatively, But there was no remaining alcohol in (A) and (B). The content of acetic acid was 4.3~5.3% as a major organic acid of vinegars. The content of tartaric acid was 340.0 in (A), 316.7 in (B), 322.6 in (C) and 391.7㎎% in (D). The content of lactic acid was distinctly high such as 277.4㎎% in (D). There were differences such as 9.2~15.5㎎% in the content of total free amino acids among grape vinegars. (D) contained 15.5㎎% of total free amino acid and (B) also highly such as 12.0㎎%. Potassium was high in grape vinegars. The content of potassium, sodium and copper was higher in (A) than (B).

      • KCI등재

        감과실 알코올 발효를 위한 효모의 분리

        정용진,서권일,신승렬,서지형,강미정,김광수 동아시아식생활학회 1997 동아시아식생활학회지 Vol.7 No.4

        To utilize abundant poor persimmon fruits effectively, it was studied on alcohol fermentation strains which were isolated and indentified from poor persimmon fruits. The strains which had exellent alcohol production ability were analysized morphogical, cultural characteristics and identified Saccharomyces cerevisiae YJK 20, Sacahroimyces kluveri DJ 97. Alcohol production ability between the isolated strains and industrial alcohol yeasts was compared in the YPD medium, persimmon extract medium. Isolated strains had high alcohol production ability in both of two medium, respectively. So it was expected that the strains, YKJ 20 and DJ 97 had good alcohol fermentation ability of persimmon fruits.

      • KCI등재

        반응표면분석에 의한 단감식초 제조조건의 모니터링

        정용진,서권일,이기동,윤광섭,강미정,김광수 동아시아식생활학회 1998 동아시아식생활학회지 Vol.8 No.1

        To utilize deteriorated sweet persimmon effectively, response surface methodology(RSM) was used to determine the optimal vinegar fermentation conditions and monitored by a divided two stage fermentation. The optimum conditions for maximum alcohol content were obtained when the first stage (alcohol fermentation) was carried out with an initial sugar concentration of 18.5°Brix, agitation rate of 140.8 rpm, fermentation time of 127.6 hr. When sugar concentration was 14°Brix, maximum alcohol content(7.1%) was predicted at fermentation conditions of 160 rpm in agitation rate, 140 hr in fermentation time. The optimum conditions for maximum acidity were obtained when second stage(vinegar fermentation) was carried out 249.5 rpm in agitation rate, 148.8 hr in fermentation time. Predicted values at the optimum conditions were similar to experimental values.

      • 성인 골퍼의 골프 니트웨어 선호 요인

        정수희,권영아 신라대학교 자연과학연구소 2007 自然科學論文集 Vol.16 No.-

        The objective of this study aims to investigate preferred factors of golf knitwears for adult men and women playing golf. The 276 questionnaire was distributed to adult men and women who live in Busan and play golf. The data analysis method was implemented by frequency, t-test, and factor analysis with SPSS_ Win10 program. The results of this study are as follows: 1. The preferred factors were classified by 7 factors: 'luxury', 'function', 'distinct' 'activity', 'casual', 'neat', and 'individual'. 2. As for the 'individual' factor, there was a significant difference between gender. Male golfers considered more important than female golfers in individual and gorgeousness image. 3. There were significant differences between age groups in the 'luxury', the 'distinct', and the 'activity' factors. As for the 'luxury' factor, the group aged 30's considered more important than the group aged over 40's. As for the 'distinct' and the 'activity' factors, the group aged 40's and above were observed to consider more important than the 30's group. 4. As for the 'distinct' and the 'activity', the group aged over 40's were observed to consider more important than the group aged 30's. The older, the more preferred young design. As for the 'function' factor, it was observed that indoor golfers considered more important than outdoor golfers.

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