Korean Dictionaries and Some Model Dictionaries of the World : Critical Essays toward the Plan for a New Korean Dictionary

Lee, Sang Sup,Nam, Ki Shim,Ahn, Sam Huan,Choi, Young Ai,Hong, Chai Song 연세대학교 언어정보개발원 1988 사전편찬학 연구 Vol.1 No.1

After briefly reviewing the history of lexcoigraphy in modem Korea, Nam Kishim tackles many problems created by the general deficiency of current Korean monolingual dictionaries in phonological morphological and semantic points. For example, most Korean dictionaries do not treat such phonological changes as the shortening of the stem vowel ㅓ in 더운, the prenominal form of the adjective 덥다, whose stem vowel ㅓ is pronounced long. He also takes issue with the practice of Korean dictionaries of including all kinds of proper names on little reliable principles : a typical dictionary enters a 600m-high hill while excluding better-known mountains higher than that. Hong Chai-song concentrates on the often misguiding information on transitive / intransitive verbs in current dictionaries. For example, a representative dictionary designates the verb 뛰다 simply as intransitive. But it is quite often used as an transitive also. In the sentence, 철수는 운동장을 뛰었다, 운동장 is the object of the transitive verb 뛰다. How could the compilers miss such an obvious fact? Hong suggests that they may have not been interested in being grammatically informative. A historical survey of the Oxford English Dictionary(OED) is given by Lee Sang-sup, with special emphasis on the vast amount of quotations from real sources contributed by thousands of volunteer readers through several decades and on its unwavering historical principle. A comparison between the OED's definition of Kimchi and a Korean dictionary's 김치 is given, showing the difference of principle in treating the same lexical item. Ahn Sam-huan presents a detailed account of Grimm's Deutsches Wo¨rterbuch which took generations of German lexicographers 133 years from its inception to its completion in 1971. On the basis of his study, Ahn suggests that future dictionary makers should cooperate as a group on a long-range comprehensive project. A moltivolume dictionary is an all-important cultural event for the whole nation, not to be influenced by private commercial interests. Choi Young-ai's survey of Chinese lexicography highlights the now on-going publication of 漢語字典 and 漢語詞典, admirable results of the cooperative effort of hundreds of Chinese scholars, a modus operandi for the Yonsei University graze to adopt in planning a new dictionary of the Korean language.

파절선 관찰 도중 발생한 피하기종: 증례보고

김민영,박성호,신유석,김의성 大韓齒科保存學會 2011 Restorative Dentistry & Endodontics Vol.36 No.6

피하기종은 치과치료 시 나타날 수 있는 합병증의 하나로서, 발치, 근관치료, 수복치료 등과 연관되어 발생할 수 있다. 피하 로 유입된 공기는 부종과 염발음을 일으키며 일반적으로는 주변 결합조직에 의해 그 범위가 한정되나 많은 양의 압축공기가 유 입될 경우 근막공간을 통해 중격동, 흉막공간, 심지어 후복막에까지 영향을 미칠 수 있어 생명을 위협하는 합병증으로 발생할 수도 있다. 이번 증례는 파절선을 관찰하던 도중에 피하기종이 발생한 환자에 대한 증례로서 그 원인과 관리, 예방법에 관해 고찰해보고자 한다. The development of subcutaneous emphysema is a well-known complication that has been reported after dental extraction, endodontic treatment, or restorative preparation. Gaseous invasion, leading to swelling, crepitus on palpation, is commonly restricted to the connective tisssues immediately adjacent to the entry site. However, the use of compressed air- and water-cooled turbines may allow large amounts of air and water to be driven through the fascial planes into the mediastinum, pleural space, or even the retroperitoneum. This case report is about the patient who presented with subcutaneous emphysema that occurred after fracture line inspection. Possible cause, treatment, and prevention of emphysema will be discussed.

HMM에 의한 연속음성 인식 시스템의 구현

심장엽,김상범,김주성,김수훈,이영재,허강인 東亞大學校 附設 情報通信硏究所 1996 情報通信硏究所論文誌 Vol.4 No.1

This paper is a study on the composition of Real-Time Continuous Speech Recognition System for Man-Machine Interface and it examines the posibility that applies to automatic system. The Continous Speech Recognition System is composed of Contivuous Distribution HMM model and algorithm of One Pass DP method. The System is composed so that it may detect start point and end point of speech data which are converted into samples by 10 KHz, 8 bit A/D whthin real time, then so that it may recognie them by one Pass DP method, display the result of recognition on PC monitor and at same time sent control data to Interface. HMM models are creadted by training for continuous speech samples which are control words, area names and digital sounds. In the result of experiment by Continuous Speech Recognition System, there are some kind of errors which are insertion, replacement and deletion of one syllable, but it examined the posibility that can by applied to Man-Machine Interface on automatic system if post-process is performed for recognition.

만성 정신분열병 환자에서 지연성 운동장애와 음성증상 및 인지기능 장애와의 연관성

심주철,반철식,성기수,이정구,정도운,정청,윤진상,김영훈 대한신경정신의학회 2000 신경정신의학 Vol.39 No.4

연구목적: 정신과 전문병원에 입원해 있는 만성정신분열병 환자들을 대상으로 첫째 지연성 운동장애의 유병율과 위험인자들을 조사하고, 둘째 지연성 운동장애와 정신분열병의 음성증상 및 인지기능 장애와의 상관성을 조사하고자 한다. 방법: 연구대상자는 마산동서병원에 입원 중인 환자 중 DSM-IV의 정신분열별 진단기준에 부합하며, 최근 3개월 이상 동일 용량의 항정신병약물 복용한 271명(남자 174명, 여자 97명)의 환자들이었다. 지연성 운동장애에 대한 평가는 Abnormal Involuntary Movement Scale(AIMS)을 이용하였고, DSM-IV와 Sc-hooler와 Kane(1982)의 진단기준 양자에 부합하는 환자들만을 지연성 운동장애군으로 분류하였다, 정신 분열병 정신병리에 대한 평가는 Brief Psychiatric Rating Scale(BPRS)와 Schedule for the Deficit Syndrome(SDS)을 이용하였고, 인지기능에 대한 평가는 Mini-Mental Status Examination(MMSE)을 이용하였다. 결과: 지연성 운동장애의 유병율은 50.9%이었고, 50세 이상, 남자에서 높았다. 그러나 입원기간과 항정신병 약물의 일일 사용량에 따른 차이는 없었다. 지연성 운동장애의 호발부위는 혀, 상지, 입술과 입 주위의 순이었다. BPRS 총점 및 소항목 척도점수와 SDS 척도점수는 지연성 운동장애의 유무에 따른 차이가 없었다. MMSE 총점 및 소항목 점수도 지연성 운동장애의 유무에 따른 차이가 없었다. 결론: 평균입원기간이 9년 이상인 만성정신분열병 환자들에게서의 지연성 운동장애의 유병율은 50.5%이었고, 연령이 가장 의미있는 위험인자임을 확인했다. 만성정신분열병 환자들이 주 대상인 본 연구에서는 지연성 운동장애와 정신분열병의 음성증상 및 인지기능 장애와의 상관성은 입증하지 못했다. Objectives: The purpose of present study was to determine the prevalence rate of tardive dyskinesia and to search for its risk factors in chronically institutionalized schizophrenic subjects. We also examined the relationship between tardive dyskinesia and both negative symptoms and cognitive impairments in the same subjects. Methods: Subjects were 271 in-patients(174 males, 97 females) at Masan Dongsuh Hospital. They met DSM-IV criteria for schizophrenia and had been taking fixed doses of antipsychotics for at least 3 months. Tardive dyskinesia was assessed by Abnormal Involuntary Movement Scale(AIMS). Cases of tardive dyskinesia were ascertained by the criteria of Schooler and Kane (1982) and DSM-IV. The rating of psychopathology was acquired using Brief Psychiatric Rating Scale(BPRS) and Schedule for the Deficit Syndrome(SDS) and the assessment of cognitive function using Mini-Mental State Examination(MMSE). Results: The prevalence of tardive dyskinesia is 50.9% and the frequency of tardive dyskinesia was high est in male above the age of fifty. But there was no statistically significant relationship between the frequency of tardive dyskinesia and both the length of hospitalization and the daily dose of antipsychotics. The frequency order of abnormal movement in the patients with tardive dyskinesia was as follows : tongue, upper extremities, lips and perioral area. We couldn't find any significant difference in the total and subscale scores of BPRS between the groups with and without tardive dyskinesia. There were no differences in MMSE scores between the groups with and without tardive dyskinesia. Conclusion: This study gave us that the prevalence of tardive dyskinesia was high in chronically institutionalized schizophrenic inpatients and that age was the most significant risk factor of tardive dyskinesia. The relationship between tardive dyskinesia and both negative symptoms and cognitive impairment, however, was not revealed.

포-만트 VOCODER의 구성에 관한 연구

심장엽,안종영,김상범,허강인 東亞大學校 附設 情報通信硏究所 1995 情報通信硏究所論文誌 Vol.3 No.1

본 논문에서는 포-만트 vocoder를 구성하여 한국어 음성 합성을 연구하였다. 포-만트 vocoder의 구성에 필요한 합성파라메터로서는 스펙트럼 모멘트법에 의한 포-만트 주파수, 최적 Comb법에 의한 피치 주파수, 단시간 평균에너지와 단시간 평균진폭, 대역폭, 음원파형, 가우시안 백색잡음이다. 합성실험은 남성 화자가 발성한 음절, 단어, 문장 등의 음성데이터를 이용하였다. 청취결과, 유무성음에 대해 각각 Rosenberg의 음원파형과 삼각파를 음원으로 적용한 경우가 우수하였다. This paper studies on a method of Korean speech synthesis by composing formant VOCODER. The parameters of speech synthesis are formant frequencies by spectrum moment method, pitch frequencies by optimum Comb method, short time average energy, short time average amplitude, bandwidth, excitation wave and gaussian white noise. In this paper, synthesis is performed using speech data which are syllable, word and sentence spoken by man. Synthesis results are good in case of using Rosenberg & Triangle wave respectively as voice source.

랫드의 생체내 카드뮴 축적에 대한 아연의 영향

심상일,조영채,이동배 忠南大學校環境問題硏究所 1993 環境硏究 Vol.11 No.-

This study was performed to find out the protective effects of zinc against accumulation of cadmium in rats. The exprimental rats were divided into two groups ; one group was administrated cadmium alone(cadmium alone group) and the other group was administrated simultaneously Cd and Zn(cadmium alone group ; Cd-I group ; 200ug/ml, Cd-II group ; 400ug/ml). Each group was administrated with different doses of cadmium (200ug/ml∼400ug/ml) and zink(100ug/ml∼1,000ug/ml) orally bia drinking water for two weeks. The gained Body weight and organ weight, cadmium levels of blood liver, kidney and spleen, hematogical values and enzyme activites were investigated for the experimental groups. The results were summarized as follows : 1. The body weights of exprimental rats were temporarily reduced, but gredually incresed after one week in each group. The weights of liver and kidney of the Cd-II(Cd 400ug/ml) group were significantly reduced compared with the control group(P<0.05). 2. The accumulation levels of Cd in the blood of rats were significantly reduced in the Cd-I group according to the Zn level was increased. But the Cd levels were significantly increased in the Cd-II group according to the Zn level was increased. 3. The accumulation levels of Cd in liver were reduced in the Cd and Zn mixed groups than the Cd alone group in the Cd-I group, but, in Cd-II group, the levels of Cd were increased in the Cd and Zn mixed groups than Cd alone group(p<0.01). 4. The accumulation levels of Cd in Kidney were significantly increased in the Cd and Zn mixed groups than Cd alone group in the Cd-I group(P<0.05), but, in the Cd-II group, the levels of Cd were reduced in the Cd and Zn mixed groups than the Cd alone group. 5. The accumulation levels of the Cd in spleen were significantly reduced in the Cd and Zn mixed groups than Cd alone group in the Cd-I group(P<0.05), but, there was not significantly differences in the Cd-II group. 6. The hematological values (RBC, WBC, Hb and Hct) were higher levels in the Cd alone group than the cd and Zn mixed groups in the Cd-I and Cd-II groups. 7. The activities of GOT, GPT, ALP, and LDH were significantly increased in the Cd alone group than the control groups, but, there was not signigicant in the Cd and Zn mixed group. According to the above results, this study suggests that Zn may accelarate the accumulation of Cd within various organs, but this metal had reducing effects on the toxicity of Cd to the hematological values and enzyme activities when the Zn was administrated simultaneously with Cd to the rats.

구강으로 돌출한 선천성 두개내 기형종 -1 부검례-

김영실,이교영,강창석,심상민,김선무 대한병리학회 1990 Journal of Pathology and Translational Medicine Vol.24 No.3

위암종과 Epstein-Barr 바이러스와의 연관성에 대한 연구

심광용,김호영,김효열,백순구,권상옥,조미연,이창훈,이종인 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Objectives: Epstein-Barr virus (EBV) has been known to be linked to a spectrum of neoplastic conditions, including nasopharyngeal carcinoma, Burkitt's lymphoma, peripheral T-cell lymphoma and Hodgkin's disease. This study aims to investigate the association of EBV with gastric carcinoma in Korea. Methods: Fifty-three cases of gastric adenocarcinoma were studied for evidence of EBV infection by EBV-encoded small RNA (EBER) in situ hybridization (ISH) on the paraffin sections and amplifying the EBV genome encoding envelop glycoprotein (gp220) with polymerase chain reaction (PCR) in fresh gastric cancer specimens. Results: EBER was detected in 7 (13.2%) of 53 gastric carcinomas and all cases were male. In 6 (85.7%) of 7 EBER-positive cases, the tumors were located in the upper and middle part of the stomach. EBER ISH study showed strong positivity in all the tumor cells, but negativity in surrouning lymphocytes, stromal cells and normal gastric mucosa. DNA PCR was positive in 23 (43.4%) of 53 gastric carcinomas, including all of 7 EBER-positive cases. Conclusion: We could observe some association of EBV with gastric carcinoma, and our findings about the charateristics of EBV-positive gastric cancers involving sex, site and histological type are similar to those in Japan. However, EBV-positive rate of gastric cancer is higher than in Japan and lower than in Western countries. Further studies to elucidate oncogenic mechanism of EBV in gastric cancer should be performed.

공황장애 환자의 성격요인과 방어기제의 특성에 관한 연구

심진현,백상빈,신영철,오강섭,노경선,이시형 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

연구목적: 본 연구는 공황장애 환자들을 대상으로 성격요인과 방어기제 검사를 실시하였으며 우울 및 사회기능 정도를 측정하여 상관관계를 알아보았다. 방 법: 1997년 9월부터 1998년 8월까지 환자들중 공황장애로 진단된 35명을 대상으로 성격요인검사(Sixteen Personality Questionnaire 한국판) 및 방어기제검사(이화방어기제검사)를 시행하여 스텐점수(1-10)화 하였고, 우울증척도(Beck Depressive Inventory 한국판) 및 사회기능장애척도(Sheehan Disability 한국판)를 시행하였다. 결 과: 1) 개별항목 (1) 성격요인과 방어기제의 척도별 평균점수에서 정상보다 높거나(8점이상) 낮은(3점이하) 척도는 없었다. (2) 성격요인중 불안감이 높았고 자아강도, 신중성, 사변성은 낮은 점수를 보였다. (3) 방어기제중 신체화, 행동화의 점수가 높았고 유우머, 억제, 이타주의, 회피, 합리화는 낮은 점수를 보였다. (4) BDI의 평균점수는 18.25±9.97이었다. (5) SDS의 평균점수는 업무항목 4.88±3.11. 사회활동/오락활동항목 4.57±2.92였다. 2) 상관관계 (1) 성별간 비교에서 성격요인은 사변성, 죄책감을 방어기제는 허세, 부정, 수동공격, 투사를 남성 이 높게 보였다(p<0.05). (2) 연령증가는 성격요인중 낮은지능과 방어기제는 예견, 해리와 상관을 허세와 역상관을 보였다(p<0.05). (3) BDI 점수는 성격요인중 지능도, 자아강도, 도덕성, 죄책감, 통제력, 불안감등과 방어기 제중 해리, 신체화등과 유의미한 상관관계를 나타냈다(p<0.05). (4) 사회기능장애척도의 업무항목은 성격요인중 죄책감, 진보성, 불안감, 도덕성과 방어기제의 신 체화, 투사등과 유의미한 상관이 있었고, 사회/오락활동항목은 성격요인의 죄책감, 불안감과 방어기제중 허세, 투사 등과 유의미한 상관관계가 있는 것으로 나타났다(p<0.05). 3) BDI와 사회기능장애척도의 업무항목간에는 유의미한 상관관계가 있는 것으로 나타났다(p<0.05). 결 론: 공황장애 환자는 성격요인검사상 불안감이 높고 자아강도, 신중성, 사변성은 낮게 나타 났으며, 신체화 등의 신경증적 방어기제를 주로 사용하는 반면 유우머, 억제, 이타주의, 회피, 합리화의 방어기제는 적게 사용하는 것으로 나타났다. 증상의 강도와 관련이 있는 우울증상은 업무활동에 영향을 미쳐 이와 관련된 중등도의 사회기능의 장애를 초래하고 있는 것으로 보인다. Objectives : The purpose of this study was to evaluate the characteristics of personality factor and defense mechanism and relationship with depression and disability. Methods : Study subjects consisted of 35 panic disorder patients diagnosed with the criteria of DSM-Ⅳ. Data were collected through Sixteen Personality Factor Questionnaire, Ehwa Diagnostic Test of Defense Mechanism, Beck Depression Inventory and Sheehan Disability Scale. Statistics employed for the analyses were Pearson correlation and independent sample t-test. Results : In personality factors and defense mechanisms, there were no definitely abnormal range of scores. But, among personality factors, tension/anxiety factor scored high and unstableness/stableness, shyness/boldness and praxernia/atunia were in low range of score. In defense mechanism, somatization and acting-out scored high and humor, suppression, altruism, avoidance and rationalization scored low. The mean BDI score was 18.25±9.97. The mean score of SDS were 4.88±3.11 in work category and 4.57±2.92 in social/leasure category. Male patients were significantly correlated with guit-proneness and atuia in personality factor and passive-aggressiveness, projection, denial and show-off in defense mechanism, compared with female patients(p<0.05). The patients` age was correlated with low intelligence in persolity factor and dissociation and anticipation in defense mechanism. It was negatively correlated with show-off(p<0.05). The BDI score was correlated with low intelligence, superego, unstableness, self-conflict, high superego and atunia in personality factor and dissociation and somatization in defense mechanism(p<0.05). There was a significant relationship between BDI score and SDS work category(p<0.05). Conclusions: Panic disorder patients show high score of tension/anxiety factor and they frequently use neurotic defense style like somatization. The depressive symptom, which depends on symptom severity, appears to have influence on work category and to cause social disability.

정신분열병 환자의 우울증에서 Paroxetine과 삼환계 항우울제 병용치료

심주철,공보금,박정환,윤영란,신재국,김정익,안동성,김용관,차인준,김영훈 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.4

저자들은 마산동서병원에 입원중인 우울증이 동반된 정신분열증 환자 10명을 대상으로 사용중인 항정신병약물에 paroxetine과 저용량의 삼환계 항우울제를 6주간 병용투여한 후 우울증상에 대한 효과와 치료의 안전성 및 약물상호작용을 알아보았다. Paroxetine은 고정량의 항정신병약물과 삼환계 항우울제에 부가하여 일일 20㎎을 6주간 병용하게 하였으며, 임상상태는 HDRS, HARS, UKU Side Effect Rating Scale등의 평가척도를 사용하여 평가하였다. 또한 약동학적 약물상호작용은 삼환계 항우울제들의 혈장농도를 HPLC로 측정하여 분석하였다. 결과는 다음과 같다. 1) 10명의 전체 대상환자에서의 HDRS 평균점수는 TCA와 paroxetine 병용투여 6주후에 통계적으로 유의하게 감소되었다. 이중 40%의 환자에서는 병용투여 6주후에 HDRS 점수상 50% 이상의 감소를 보여, 일부의 환자들에서는 정신분열병에 동반된 우울증상의 치료에 소량의 삼환계 항우울제와 paroxetine의 병용치료가 효과가 있음을 확인하였다. 2) 두 명의 환자에게서 심각한 약물독성이 발생하였다. 이중 한 명은 삼환계 항우울제의 높은 혈중농도로 인한 항콜린성 위기(anticholinergic crisis) 소견을 보였으며, 다른 한 명은 인지기능 및 의식수준은 명료하였으나 망상과 환각증상이 약화되는 소견을 보였다. 따라서 본 연구에서 시도된 복합적 약물치료의 경우, 삼환계 항우울제의 혈중농도의 측정을 포함한 세심한 임상적 추적이 필요하다고 생각된다. 3) 기저치의 amitriptyline과 그 대사물인 nortriptyline의 농도합. imipramine과 대사물인 desipramine의 농도합은 각각 47.8-226.5ng/㎖. 80.5-395.6ng/㎖였으며 일반적으로 이들 약물들의 단독사용시에 문헌에 보고된 혈중농도를 훨씬 상회하고 있었다. 이는 병용투여된 항정신병 약물 약시 강력한 CYP2D6 효소억제제로서 기저치의 삼환계 항우울제들의 혈장농도를 이미 상당히 증가시켰던 것으로 판단되며, 그러한 결과로 인해 본 연구에서는 paroxetine이 이전의 문헌보고들과는 달리 뚜렷하게 삼환계 항우울제들의 혈장농도를 증가시키지 못하였다. 본 연구는 SSRI와 삼환계 항우울제의 병합 투여가 우울증의 개선 효과를 빠르게 하고, 치료역을 넓히고, 약물상호작용의 결과 paroxetine이 삼환계 항우울제의 혈중농도를 증가시킨다는 기존의 연구결과를 이용하여 정신분열병 우울증상의 치료에 parotextine과 소량의 삼환계 항우울제를 병용하는 방법을 시도해 본 연구이다. 저자들은 이러한 약물치료가 일부의 환자들에게서 효과가 있음을 관찰하였으나, 항정신병약물과 삼환계 항우울제를 병용투여 할 경우는 물론 이에 paroxetine과 같은 선택적 세로토닌 재흡수 억제제를 병용할 경우 복합약물상호작용의 결과로 약물독성의 위험성이 크며 세심한 주의가 필요함을 경험하였다. Depression is well-known to comorbid with several psychiatric disorders. Many schizophrenics also suffer from depression in the course of their illness. Combined therapy of SSRI and tricyclic antidepressants were reported to have benefits in some depressed patients. Paroxetine, a potent CYP2D6 inhibitor, increases the blood levels of tricyclic antidepressant markedly. Using paroxetine, we tried this combined therapy in the treatment of depressive symptoms in 10 chronic schizophrenic inpatients and evaluated its efficacy and drug interactions between paroxetine and tricyclic antidepressants. The following results were obtained : 1) The mean score of Hamilton's Depression Rating Scale(HDRS) was reduced significantly after 6 weeks-trials of this combined therapy for the mild depressive symptoms in 10 chronic schizophrenics. In four patients, 50% or more reductions in the scores of HDRS were noticed at final evaluation. 2) Two among our 10 subjects experienced severe toxic behavioral problems. Anticholinergic crisis with toxic confusion due to high blood levels of tricyclics was found in one patient and the other showed rapid clinical deterioration in his psychotic symptoms such as delusion and hallucination without any consciousness alternation. 3) Baseline plasma levels of tricyclics before adding paroxetine were higher than expected in our chronic schizophrenic subjects maintained with their antipsychotic medications. Several antipsychotics were also known as a potent CYP2D6 inhibitors and to increase the blood levels of tricyclics. Because the blood levels of tricyclics had already increased significantly by the use of antipsychotics, adding paroxetine to antipsychotics and tricyclic antidepressant in our subjects could increase the blood levels of tricyclics not so much as previously reported in the literatures.