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      • 미취학 아동에서 산성 고자당 액상배지를 사용한 치아우식활성검사성적과 치아우식경험도의 상관성에 대한 타액 및 치태 검체의 영향에 관한 비교연구

        안동성,이흥수,한경수,김수남 원광대학교 치의학연구소 1992 圓光齒醫學 Vol.2 No.2

        The purpose of this study was to compare the effect of saliva specimen and plaque specimen on the relationship between dental caries experience and dental caries activity test score by acid high - sucrose liquid medium in preschool children. The caries experience and caries activity of 270 preschool children were examined. Caries activity was measured by the acid high-sucrose liquid medium which was each inoculated by dental plaque and the saliva. The medium was composed of surose 30%, beef extract 0.1%, NaCl 0.2%, bromocresol green 0.01%. The pH of medium was adjusted to pH 5.4 by lactic acid solution. 5㎖ of medium was poured into capped test tubes which were then autoclaved. The plaque specimen was sampled from the subject's upper buccal toothsurfaces by a cotton applicator and then it was directly put into the tube. The saliva specimen was dropped directly into the test tube. The media were incubated at 37℃ for 96 hrs. Every 24 hours pH was readed by observing the color change of pH indicator bromocresol green in the medium with the color standard. 3 or 4 days' pHs were converted to scores and then added together. pH drop of plaque specimen was faster and greater than saliva specimen. The correlation between caries experience and plaque specimen score was higher than that of caries experience and saliva specimen score. Therefore, plaque seemed to be more appropriate as the specimen of the caries activity test using acid high-sucrose medium than saliva.

      • Doxylamine succinate 과량복용후 섬망상태를 일으킨 여아 1례

        안동성,이기철,이정호 인제대학교 1994 仁濟醫學 Vol.15 No.2

        항히스타민제는 습관성, 금단증상이 없는 비교적 안전한 약물로 의사의 처방없이 약국을 통하여 쉽게 구입이 가능하다. 이런 까닭에 이 약물에 의한 사고와 자살목적으로 과량복용하는 일이 발생하고 있는데 급성중독에서는 중추신경 흥분작용이 심각하게 발생하여 행동과다, 보행실조, 흥분, 환각, 섬망, 진전 및 경련까지 유발되며 또한 중추신경계의 억제작용이 중복되는 경우 혼수상태를 초래하고, 호흡부전, 심부전을 일으켜 사망의 원인이 되기도 한다. 저자들은 doxylamine succinate(Zamero) 625mg을 자살 목적으로 복용한 소아에서 선명한 환시, 환촉과 지남력 장애를 동반한 급성 섬망상태를 보인 증례 1례를 치험하였기에 문헌고찰과 함께 보고하였다. The authors experienced a case of delirium induced by doxylamine overdose. A 12 year- old female patient ingested 25 tablets of Zamero for the purpose of suicide. The patient showed symptoms of delirium such as prominant visual and tactile hallucination with cognitive deficit, and other autonomic dysfunctions due to anticholinergic effects of doxylamine succinate. The patient was recovered from delirious strate with general symptomatic care including diazepam, lorazepam and haloperidol administration. The emotional crisis on the intrafamilial conflicts and the psychosocial functioning of patient was intervened through the psychotherapeutic approach and the familial support.

      • KCI등재
      • KCI등재

        식염과 중조가 구강세균의 산 생성에 끼치는 영향에 관한 생체외 연구

        안동성 대한구강보건학회 1991 大韓口腔保健學會誌 Vol.15 No.1

        Seven experimental mouthrinse solutions were made by the combination of 0.05% NaF, 5% and 10% NaCl, and 5% sodium bicarbonate. Streptococcus strains 10449, OMZ 65, and OMZ 175 were mixed and incubated in BHI broth. Plaque and saliva samples were collected from a ten-year-old boy who had high caries activity and also incubated in BHI broth. 2.5×80㎜ wood sticks were autoclaved and used to carry oral bacteria. They were immersed in the cultured broth for four hours and then immersed in the mouthrinses for four minutes. Inoculated and treated wood sticks were put into the culture tubes which contained 6㎖ media of sucrose 5%, beef ectract 0.4%, bromcresol green 0.04%, and NaCl 0.5%, and the tubes were incubated at 37℃ for 18 hours. Final pH was readed by use of color standard. In S. mutans group, soda and mixture of fluoride and 10% salt inhibited pH drop more than the others. In plaque group, soda inhibited pH drop most. S. mutans showed a tendency to be more sensitive to salt and soda than the other bacteria.

      • KCI등재

        정신분열병과 류마치스 관절염 사이의 음성적 상관관계 : 역학 및 방어적 요인으로서 Prolactin과 Estrogen

        안동성,이영호,이윤우,Ahn, Dong-Sung,Lee, Young-Ho,Lee, Yoon-Woo 대한생물정신의학회 1999 생물정신의학 Vol.6 No.1

        The purposes of this study were to test the negative association between schizophrenia and rheumatoid arthritis(RA) and to clarify the role of prolactin and estrogen as protective factors in this association. The author compared the prevalence rate of RA between 561 patients with schizophrenia and 222 patients with mood disorder. For investigating the role of estrogen and prolactin, the author checked the plasma prolactin and estradiol level in 80 patients with paranoid schizophrenia and 77 patients with RA. The results were as follows. 1) Epidemiological data The prevalence rate of RA in the schizophrenic group was 0/561 and that of RA in the mood disorder group was 2/222. To compare these results between two groups, the author applied the Binomial test using the average prevalence rate of RA(0.8%) in the general population as a reference rate. The prevalence rate of RA in the schizophrenic group was significantly lower than that of RA in the general population. However, the prevalence rate of RA in the mood disorder group was not significantly different to that of RA in the general population. 2) Comparison of plasma prolactin and estradiol level between two groups The plasma level of prolactin in the schizophrenic group was significantly higher than that of prolactin in the RA group(p=0.000). However, the plasma level of estradiol in the schizophrenic group was significantly lower than that of estradiol in the RA group(p=0.017). These results were not consistent across gender. To contrast with the results in the female group, which were consistent with the results in the total subjects, for the male group, the plasma levels of prolactin and estradiol in the schizophrenic group were significantly higher than those of prolactin and estradiol in the RA group. These results support the results of previous studies which confirm the negative association between schizophrenia and RA. These results also suggest that the elevation of plasma prolactin level in the patients with schizophrenia has a antirheumatic effect while the elevation of plasma estradiol level in the patients with RA has a anti-schizophrenic effect, and that these effects act as a possible mechanism in the negative association between two disorders. However, these results suggest that this association is specific to female patients.

      • KCI등재

        남성 직장인에서 홉연과 우울,스트레스 및 다른 물질사용과의 관계에 대한 연구

        안동성,이영호,정영조 대한신경정신의학회 1994 신경정신의학 Vol.33 No.6

        Department of Neuropsychiatry, Seoul Paik Hospital, College of Medicine, Inje University, Seoul Objective: To investigate the relationship between smoking and depression, stress perception, an4 other substance use. Methods : With 753 male management officers who visited to Seoul Paik hospital for the general health check-up, we divided them into five groups(nonsmoker, nondependent ex-smoker, dependent ex-smoker, nondependent smoker, dependent smoker) according to the diagnostic criteria of DSM-III-R. With Beck Depression Inventory (BD I) and Global Assessment of Recent Stress(GARS) scale, depression and stress were evaluated. And Short Michigan Alcoholism Screening Test(SMAST) was applied for the assessment of degree of alcohol dependence. Results : 1) In smoker group, mean age, mean duration of education, and annual income were significantly lower than those of ex-smoker and nonsmoker group(p〈.0.05). 2) There was no noticeable difference in m ean total score of BDI am ong five groups. Mean total score of GARS was significantly different am ong five groups and this difference was mainly due to difference between dependent smoker, ex-smoker group and the other groups (each p<0.05). Percent of possible and definite alcohol dependence, and daily mean use of coffee were significantly high in smoking group than the other groups (each p<0.05). 3) To com pare between depression group (above 18 of total mean score of BDI) and nondepnession group(below 18 of total mean score of BDI), there was no significant difference in m ean total score of BDI, daily use of coffee, and num ber of alcohol use and dependence. But m ean total score o f GARS and mean score of all items of GARS were significantly high in smoking group (p<0.05). 4) Smoking h ad a significant effect on coffee use and alcohol drinking h ad a significant effect on depression(p<C0.05). While both smoking and alcohol drinking had a significant effect on stress perception, smoking had more effect Conclusion : These results may suggest that the degree of stress perception in male managem ent officers is closely related with smoking & alcohol use in order. In the relationship between smoking and stress perception, degree of nicotine dependence is more crucial than current smoking itself. In contrast with above result, depression is more closely related with alcohol use than smoking, and current smoking itself is more important than degree of nicotine dependence in relationship between depression and smoking. And significant relation among coffee use, alcohol use, and smoking can explain possible combined use of these substances in the same user.

      • KCI등재

        남성 직장인에서 흡연과 우울, 스트레스 및 다른 물질사용과의 관계에 대한 연구

        정영조,이영호,안동성 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.6

        Objective : To investigate the relationship between smoking and depression, stress perception, and other substance use. Methods : With 753 male management officers who visited to Seoul Paik hospital for the general health check-up, we divided them into five groups(nonsmoker, nondependent ex-smoker, dependent ex-smoker, nondependent smoker, dependent smoker) according to the diagnostic criteria of DSM-III-R. With Beck Depression Inventory(BDI) and Global Assessment of Recent Stress(GARS) scale, depression and stress were evaluated. And Short Michigan Alcoholism Screening Test(SMAST) was applied for the assessment of degree of alcohol dependence. Results : 1) In smoker group, mean age, mean duration of education, and annual income were significantly lower than those of ex-smoker and nonsmoker group(p<.0.05). 2) There was no noticeable difference in mean total score of BDI among five groups. Mean total score of GARS was significantly different among five groups and this difference was mainly due to difference between dependent smoker, ex-smoker group and the other groups(each p<0.05). Percent of possible and definite alcohol dependence, and daily mean use of coffee were significantly high in smoking group than the other groups(each p<0.05). 3) To compare between depression group(above 18 of total mean score of BDI) and nondepression group(below 18 of total mean score of BDI), there was no significant difference in mean total score of BDI, daily use of coffee, and number of alcohol use and dependence. But mean total score of GARS and mean score of all items of GARS were significantly high in smoking group(p<0.05). 4) Smoking had a significant effect on coffee use and alcohol drinking had a significant effect on depression(p<0.05). While both smoking and alcohol drinking had a significant effect on stress perception, smoking had more effect. Conclusion : These results may suggest that the degree of stress perception in male management officers is closely related with smoking & alcohol use in order. In the relationship between smoking and stress perception, degree of nicotine dependence is more crucial than current smoking itself. In contrast with above result, depression is more closely related with alcohol use than smoking, and current smoking itself is more important than degree of nicotine dependence in relationship between depression and smoking. And significant relation among coffee use, alcohol use, and smoking can explain possible combined use of these substances in the same user.

      • KCI등재

        체중조절 방법에 따른 휴식기 대사량, 호흡율 및 신체계측치의 변화

        이영호,안동성,이민규,이혜경,허시영,김민숙,홍지영 한국건강심리학회 2008 한국심리학회지 건강 Vol.13 No.4

        This study was tried to investigate that REE and RQ changes, and contents of weight loss might be different by weight control methods and to prove the prediction effects of REE and RQ for weight changes. For these purposes, 62 college women(BMI>23) were voluntarily recruited to response for advertizing. With the 2nd stepped selection procedures, 47 persons(15 diet group, 18 exercise group and 14 medication(Reductil 10mg-15mg/d) group) were finally selected. During the 3months course of study, 9 persons(4 for dieting group, 3 for exercise group and 2 for medication group) were dropped. Persons of diet group were forced to maintain 500kcal deficit per day of food intake on the basis of estimated daily requirements by REE at start point and present level of activity. Persons of exercise group also forced to maintain 500kcal deficit per day by exercise on the basis of estimated daily requirements by REE at start point and present level of food intake. Persons of medication group were maintained 10mg-15mg of Reductil per day and forced to maintain present level of food intake and activity. All persons should keep the write the daily eating diary and activity diary with pedometer and were monitored by specialists on weekly basis. Group LEARN program was done weekly for each group. At start, after 1month, and 3 months, anthrometric data(weight, BMI, FFM, FM, WC), REE and RQ were obtained. The results were as follows. First, There were no significant differences among three groups in the changing amounts of REE and RQ during 3 months. For each group, there was no significant change in the value of REE and RQ. However, changing patterns of REE and RQ according to time process were different by groups. Second, there were significant differences for each group in the changing amounts of weight, BMI, FFM, FM and WC during 3 months but there were no significant differences among three groups. However, changing patterns of FFM, FM and WC according to time process were different by groups. This might suggest that even weight loss was achieved, changing contents could be different by weight control methods. Third, REE and RQ value had no prediction effects for 3 months duration weight changes. Result that changing patterns of REE and RQ according to time process were different by groups even that there were no significant differences among three groups in the changing amounts of REE and RQ during 3 months may suggest that major weight control strategies can be arranged or mixed for effective weight control to keep the high REE and low RQ during the courses of weight control. Negative result for the prediction effects of REE and RQ may suggest the necessary to investigate it's relation with amounts of weight change or/and time lags after weight change. 본 연구는 체중조절 방법이 휴식기 에너지 소비량(resting energy expenditure : REE)에 어떤 영향을 주는지를 알아보고, 특히 신체계측치의 변화가 체중조절 방법에 따른 체중변화의 내용을 예측하는지, 에너지 소비 지표중 하나인 REE와 호흡율(respiratory quotients: RQ)이 체중감소를 예측하는 지표로서의 의의가 있는지를 알아보기 위해 이루어졌다. 참여자는 서울시내 소재 여자대학에 재학중인 학생으로 본 연구목적에 동의한 여학생 중 신체질량지수가 23이상으로 과체중에 속하고 식사문제와 심리적 문제 및 기본적인 신체검사에서 이상소견이 없는 47명을 대상으로 하였다. 이들을 본인의 선호에 따라서 체중조절방법 가운데 식사조절 15명, 운동조절 18명, 약물투여 (일일 reductil 10mg) 14명을 할당하였다. 참여자 가운데 탈락된 9명(식사조절군 4명, 운동조절군 3명, 약물투여군 2명)을 제외한 38명의 자료를 최종 분석하였다. 식사조절군은 REE 검사를 근거로 현재 체중을 유지하는데 필요한 열량에서 일일 500kcal를 줄인 열량을 처방하였고 운동조절군은 운동부하검사를 실시하여 현재 체중을 유지하는데 필요한 열량에서 일일 500kcal를 소비할 수 있는 유산소 운동과 근력운동 처방하여 실시할 수 있도록 하였다. 약물투여군은 reductil 10mg을 투여하고 1개월 동안 약물을 복용하고 2kg이하로 변화가 온 경우에는 15mg을 투여하였다. 프로그램 시작 시, 1개월 후, 그리고 3개월 후 신체계측치와 REE, RQ를 측정한 결과,. 체중조절 방법에 따라 시간의 경과에 따른 REE의 변화와 RQ의 변화가 전체적으로는 유의한 차이를 보이지 않았으나 각 방법에 따라 시간에 따른 REE의 변화양상과 RQ의 변화양상은 다를 수 있는 가능성을 보여주었다. 그리고 체중조절 방법에 따라 시간의 경과에 따른 각종 신체계측자료는 각 군에서 유의한 차이를 보이지 않았으나 체중변화와 FFM, FM 및 WC의 변화 양상은 세군 간 다른 양상을 보였다. 초기 REE 값이나 RQ가 단기적이기는 하나 3개월간의 체중변화를 예측하는데 유의하지 않았다. 이런 결과는 효과적인 체중조절을 위해 체중조절 경과에 따라 체중조절 전략을 변화시키는 것이 유용할 수 있음을 시사한다. 마지막으로 본 연구의 제한점과 미래 연구에 대해서 논의하였다.

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