백서의 복강내에 투여한 Mitomycin-C-Polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

송규상,강대영,최정목,노승무,정경수,오정연,김진향,양준목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

To evaluate the in-vivo effects of mitomycin-C-polyglycolic acid composite(MMC-PGA) the disk: shaped composite were implanted into the peritoneal cavity of the Sprague-Dawley rats. The pathologic changes were examined at various time points up to 12 weeks. Initially the soft tissue around the inserted disks showed capillary congestion at 3 days. Inflammatory infiltrates with foreign body giant cells appeared from the 2nd week and reached peak response at 6-8 weeks. These reaction diminished prominently at 12 weeks. No specific pathologic change was found in the liver, the kidneys, and the heart. The above results suggest that the MMC-PGA composite can serve as a new device for intraperitoneal chemotherapy of various types of cancers.

아급성기 대량 재해 지역에서의 의료 지원 : '99 대만 지진 의료 지원을 중심으로

송형곤,강보승,송근정,정연권 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3

Background: There was a powerful earthquaken(Richter Scale 7.6) In Tiawan, on Sep.21, 1999. We supported the organized medic긴 services in that area during 5 days. Methods: We made the protocol and analyzed the results prospectively. Results: We took care of a total of 708 patients from sep. 23 to sep. 27. Traumatized patients related to the earthquake were 245(34.6%), and most of them had minor injuries. Two hundred thirty-nine(239, 33.8%) patients visited us for medical disease related to living in a group. There were 29(4.1%) patients who complained of neuropsychiatric problems due to the post-earthquaken stress. Because the condition of the patients was so bad, 18(2.5%) were transferred to receive more medical services. Conclusion: In disaster area, organized medical services have two different roles, especially in the subacute stage. One is responsibility for real emergency medical care, and the other is medical care of non-emergency patients.

아파트 단위평면의 구성면적변화에 따른 거주후 평가(POE)에 관한 연구

송대호,장승재,박춘근 동아대학교 공과대학 부설 한국자원개발연구소 1995 硏究報告 Vol.19 No.2

The study is presented the model by Stepwise Multiple Regression Analysis, practiced Post Occupancy Evaluation with factor which is to be considered for the change of constituent area after grasping change of constituent area. Apartment unit plan composition is classified in private space, public space, supporting space. The results are as follows: Total constituent area ratio of the existing plan was 39.5 : 40.8 : 19.7 and dwelling consciousness one was 36.4 : 44.0 : 19.6. Compared private space with public space, public area requested increase rather than private area. The Multiple Regression formula between each factor and the constituent area is represented to by HY(Cl)=0.3118+0.52483(C2)+0.28383)C3)+0.10922(C6), but estimate ability of this formula comes into 53.3%.

치성 각화성 낭종에 대한 고찰

송승희,이선재,조갑주,서영진,고부일,유기준,박영주,안병근 한림대학교의료원 1994 人間科學 Vol.18 No.11

급성 심근경색후 생존심근 진단에서 Dobutamine 심초음파도와 Thallium 심근스캔의 정확성 비교

이근,강덕현,송재관,이철환,최기준,홍명기,김재중,박성욱,박종훈,박승정 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.2

播種期 및 栽植密度가 단옥수수와 찰옥수수의 이삭形質에 미치는 影響

鄭丞根,許成秀 충북대학교 농업과학기술연구소 1992 農業科學硏究 Vol.10 No.1

This study was conducted to clarify the effects of planting time and planting density on ear characters in sweetcorn and waxycorn and, therefore, to provide informations necessary to improve quality and marketability of sweetcorn and waxycorn ears. Sweetcorn cultivar Goldencrossbantam 70 and a local waxycorn variety were planted on May 6 and June 26 at the planting densities of 4,000,6,50 and 9,000 plants per 10a. Plant and ear height were reduced as planting date was delayed and planting density was increased in both sweetcorn and waxyxorn. In sweetcorn, unhusked and husked ear weights were decreased about 60∼80g as planting was delayed and about 10∼20g as planting density was increased. In waxycorn, both planting date and planting density did not inf1uenced on ear weight. In sweetcorn, unhusked, husked and filled ear lengths wers reduced about 2∼4㎝ as planting date was delayed and about 1㎝ as planting denisty was increased. In waxyxorn, ear length was not affected by planting date or planting density. In both sweetcorn and waxycorn, distribution and variations of ear weight and length were smaller for husked ears than those for unhusked ears. Number of kernel rows per ear was decreased in June 26 planting, but planting density showed no influence in sweetcorn. However, both planting date and planting density did not sow any effect on row number in waxycorn.

안와골절의 외과적 접근에 대한 증례보고

민승기,이은택,오승환,이동근,고세욱,송종민,최성림 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.3

The Orbital fracture which is often combined with midface fracture can cause decreased visual acuity, limitation of eyeball movement, diplopia, enophthalmos, etc. Traumatic orbital fracture causes change of orbital volume, results in diplopia and enophthalmos thus, accurate repositioning of displaced bone and reconstruction of orbital defect with autogenous materials(cranial, rib, iliac bone, cartilage and fascia lata) or alloplastic materials(gelatin film, polyglactin mesh, methylmethacrylate, Teflon, silicone, Supermid, hydroxyapatite and metal). The key point of reconstruction of orbit is accurate repositioning of displaced orbital floor, lateral, medial orbital wall and sufficient bonegraft in anatomical defect. As this cases, we obtained good results through transconjunctival and coronal approach who were required orbital reconstruction. Also, we accurately diagnosed orbital fracture with C.T., 3D model and good result for orbital reconstruction with sufficient parietal block bone graft during average 16.8 months follow-up.

지식기반 사회에서의 정보민주주의와 정보복지 정책 : 정보편중 및 과독점 해소방안 A Solution for the Digital Divide

양승목,송호근,조권중 서울대학교 사회과학연구원 2002 한국사회과학 Vol.24 No.1

본 연구는 지식기반 사회에서 나타나고 있는 정보의 편중과 과독점을 정보격차 내지는 정보 불평등의 문제로 인식하고, 정보민주주의와 정보복지라는 두 가지 이론적 논의를 바탕으로 지식기반 사회의 정보격차와 정보불평등을 극복하는 정책적 대안을 모색하고자 하였다. 이를 위해 먼저, 정보격차를 야기하는 사회적 기제를 논의하고 각종 사회조사 통계의 분석을 통해 정보격차의 현황을 검토하였다. 그리고 정보격차를 극복하기 위한 노력의 이론적 근거로서 정보민주주의와 정보복지 개념을 논의하고, 국내외의 정보격차 해소 정책에 대한 사례연구를 실시하였다 그 결과, 정보격차와 정보불평등을 해소하려는 기존의 노력들은 주로 하드웨어든 소프트웨어든 정보통신기술에 대한 접근과 그것을 사용할 수 있는 능력의 배양에 초점을 맞추어 왔음을 알 수 있다 이러한 노력들이 나름대로 충분히 의미있고 또 중요한 것이지만, 정보격차를 궁극적으로 해결하기 위해서는 단순히 물리적 접근을 보장하는 차원이 아니라 정보불평등을 야기하는 사회 구조적 문제를 직시하고 정보사회에서의 사회적 삶의 가치를 중시하는 새로운 형태의 정책방안이 필요하다. This study examines the theoretical implications of 'information democracy' and 'information welfare' in the context of the rapid development of Information and Communication Technologies ICTs), and suggests policies to overcome the digital divide or information inequality between information rich and poor. Based upon an extensive survey of social statistics and the various policies implemented in Korea, the United States, and the United Kingdom, this study argues that the previous efforts to prevent the digital divide are limited because they have focused on broadening access to ICT hardware and software and providing widely available basic training in their use. As important and welcome as these efforts, we suggest the policies that move beyond a concern with physical access to ICTs, paying more attention to the structural aspect of information inequality as well as the value of social life in the age of information society.

Rat의 복강에 삽입한 Filorouracil-Polyglycolic acid제형의 Fluorouracil용출에 관한 연구

노승무,정경수,오정연,김진향,양준묵,강대영,송규상,최정목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

A common form of relapse in adenocarcinoma of the stomach is intraperitioneal dissemination, in fact, among gastric adenocarcinoma patients who have undergone surgery intended to cure, approximately 50% of the patients develope initial recurrence in the peritoneal cavity regardless of the anatomic site of the primary tumor within the stomach. The efficacy of systemic postoperative chemotherapy to prevent peritoneal recurrence of gastrric adenocarcinoma is not satisfactory. There is still a great need for improved therapeutic strategies on the disseminated microscopic disease and small miliary nodules remaining on the peritoneal surface or lymphatics after operation. The authers have made fluorouracil-polyglycolic acid composite disks(Fu-PGA disks) with fluorouracil and biodegradable polymer: polyglycolic acid for more effective intraperitoneal chemotherapy. We inserted the Fu-PGA disk(s) in the peritoneal cavity of rat and pharmacokinetic study was performed to measure fluorouracil concentration in the peritoneal fluid, plasma, liver, kidney and heart tissue at 24 hour, 72 hour and 168 hour after insertion of Fu-PGA disk(s). Myelosuppressive action of this composite also was determined following its administration. The data of this study suggested that Fu-PGA composite will be a new device releasing drugs in a controlled manner and having targetability to peritoneum, and this device will be improving the efficacy of intraperitoneal chemotherapy for gastric adenocarcinoma.

위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.