식품향 개발을 위한 Reaction Flavor 기술

유승석 호남대학교 산업기술연구소 2000 산업기술연구논문집 Vol.8 No.-

식품의 품질은 그 속에 함유되어 있는 여러 가지 영양성분 외에도 식품의 색, 물성과 함께 향에 의해 향상되는 것으로 알려져 있다. 이러한 식품향에 관한 여러 연구분야 중 실제의 식품이 함유하고 있는 여러 가지 전구체를 이용하여 제조하는 것은 매우 중요한 의미를 가지고 있다. 그중 특히 각종의 식품향을 가열에 의해 제조하는 분야를 reaction flavor technique 이라고 한다. 원하는 향을 제조하기 위해 우선 목적 식품의 휘발성 향기성분에 관한 지식과 정보가 요구되어 지며, 이들을 생성하는 전구물질에 관해 이해하고 어떤 경로를 통하여 향의 생성을 유도할 수 있을 것인지 디자인하는 것이 매우 중요하다. 따라서 대부분의 가열식품에 사용되는 주요 전구물질과 반응기작에 관해 검토하고, 이러한 가열반응의 결과나 경로에 영향을 미치는 인자들에 관하여 연구하였다. The quality of food is determined by color, texture, and flavor besides the food components with nutrient. One of the major concern for the flavor study is how to generate with the precursors in food. Specially, the technique using thermal reaction is very useful and natural oriented method. In this paper, the common precursors were examined to build up the flavors for the cooked or processed foods. And the main mechanism of the reactions including Strecker degradation was re-evaluated along with the factors affecting the final reaction products.

식품용 종이포장재의 특성 및 안정성에 관한 연구

유승석 호남대학교 2005 호남대학교 학술논문집 Vol.26 No.2

The food packaging is usually used for the protection, preservation and distribution of foods. There are mainly four groups of materials for food packaging, that are plastics, paper and paperboard, metals, and glass. Plastics are one of the most popular one and having frequently wide range of uses. When we select these food packaging materials, it is required many factors based on the types of foods and the processing methods of those. The consumption of the paper packaging expects to be much increased because the needs of the society in the future, due to the facts of safety and environmental benefits. This research had investigated on the manufacture of paper packaging from woods, typical classification of the paper packaging products, and also the safety of those. In the case of the paper packaging for food, it is specially important to analyze and study continually to confirm the safety or sanitation since most of the papers used as food packaging together with other materials besides the toxicity or contamination of paper itself.

육류식품향에 기여하는 주요 황함유화합물

유승석 호남대학교 산업기술연구소 2001 산업기술연구논문집 Vol.9 No.-

식품의 품질에서 중요한 한 요소인 향미의 특성을 소비자의 선호도와 판매량이 많은 3대 육제품인 쇠고기와 돼지고기, 그리고 닭고기를 중심으로 하여 각각의 육류향(savory flavor)의 고유한 특성과 공통점을 황화합물을 근간으로 하여 비교하였다. 대부분의 육제품이 고유한 character impact 화합물을 갖지 않는 것을 고려해볼 때 육제품의 경우 주로 meaty 특성을 나타내는 황 화합물과 fatty 특성을 갖는 알데하이드의 함량비율이 각 육제품의 향미특성을 결정짓는 가장 중요한 인자라고 판단되며, 지방조직에 함유된 고유한 성분과 이 부위에 존재하는 지방성분이 그 식품 고유의 향미에 중요한 영향을 주는 것으로 보고되었다. 또한 소고기를 비롯한 모든 경우의 육제품의 향미에는 황화합물이 매우 중요한 역할을 하는 것으로 결론 내려졌다. The characteristic flavor of three major meat is surveyed and compared in the aspect of the sulfur related compounds. Most of the meat products do not have character impact compounds although there are still important constituents in it. The most important factor to distinguish the flavor among each product due to the combination of meaty note derived from sulfur containing compounds as well as fatty note which from several aldehydes. And the unique constituents with lipid affect the sensory character of the flavor in each meat product. Specially, the presence of sulfur compounds in most meat products contributes to the flavor of the food.

링 예약 알고리즘을 이용한 ATM 스위치

주우석,박경희,유승열,최병석 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

We propose a new architecture of multicast ATM switch which has input and output buffers and uses Multicast Ring Reservation Algorithm to resolve output port contention. This new algorithm eliminates internal cell loss due to contention, and reduces the hardware complexity. We can dynamically control the number of cells routed to a specific output port during one cell time with this contention resolution algorithm. The computer simulation is performed under bursty traffic condition to show the performance of this proposed multicast ATM switch.

성장과 운동수행능력 향상에 도움을 주는 식이조성물의 개발

윤승원,정은희,양동식,이홍석,윤유식 대한지역사회영양학회 2003 대한지역사회영양학회지 Vol.8 No.3

We developed a dietary supplement using natural herbs and nutrients for the growth and exercise performance improvement. It called JR-22 supplement containing distilled extracts of natural herbs to remove bitterness and the addition of Vitamin B1, B6, Ca and xylitol. We investigated on the effect of JR-22 supplementation on the maximal exercise performance, IGF-1 (insulin like growth factor-1) concentration and antioxidant activity in SD rat model. In result, JR-22 supplement group was better than control group about 10% in exercise performance test and increased about 63% of IGF-1 concentration in blood. In addition, the oxidative damage induced by exercise was reduced by JR- 22 supplementation. Therefore, we suggested that JR-22 supplementation enhanced effectively exercise performance and IGF-1 concentration and reduced to oxidative stress in muscles. Also, we analysed biochemical factors in blood for the safety of JR-22 supplement. We known that there is no change of blood lactic acid, ammonia, inorganic phosphorous ion and creatine kinase activity.

알쯔하이머형 치매 환자에서 우울증의 유무에 따른 인지기능과 일상생활 수행능력의 차이

김승민,최태규,안석균,손석한,유계준,오병훈,오희철 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.2

연구목적 : 알쯔하이머형 치매 환자에게 있어서 중요한 행동증상중의 한가지인 우울증의 다양한 범위로 보고되고 있으며 우울증과 인지능력 및 기능적 능력과의 관계에 대한 연구가 매우 중요하게 부각되고 있다. 본 연구의 목적은 지역사회에 거주하는 경도 및 중등도의 알쯔하이머형 치매 환자를 대상으로 우울증이 일상생활 수행능력과 인지기능의 특정 영역과 연관이 있는지의 여부를 알아보기 위함이다. 방 법 : 본 연구대상은 경기도 광주군에 거주하는 65세 이상의 알쯔하이머형 치매 노인 48명이며, 한국판 Mini-Mental State Examination(이하 MMSE-K), 한국어판 신경행동학적 인지상태 검사(이하 한국어판 NCSE), 한국형 노인우울검사(이하 KGDS), 기본적인 일상생활 수행정도(이하 ADL), 그리고 도구적인 일상생활 수행정도(이하 IADL)를 연구도구로 하여 이들로부터 자료를 수집 조사하였다. 연구대상은 KGDS에 의해 우울 치매군과 비우울치매군으로 분류하였으며 두 군간의 상기 척도에 의해서 얻어진 결과를 χ²test 및 independent t-test를 이용하여 분석하였다. 결 과 : 우울 치매군과 비우울 치매군은 성별, 연령, 교육수준 및 MMSE-K 점수의 유의한 차이가 없었다. 우울 치매군은 비우울 치매군보다 ADL의 한 항목인 목욕하기에서 유의한 저하를 보였다. 우울 치매군은 비우울 치매군보다 IADL의 총점 및 식품점에 가서 장보기, 집안일(청소나 정리정돈), 금전 관리의 3개 항목에서 유의한 저하를 보였다. 그러나 우울 치매군은 비우울 치매군은 한국어판 NCSE를 이용한 인지기능의 영역별 비교에서는 유의한 차이를 보이지 않았다. 결 론 : 이상의 결과로 미루어 볼 때 알쯔하이머형 치매 환자에서의 우울증은 기본적인 일상생활 기능의 일부와 도구적인 일상생활 기능의 저하와 상당한 관련 있고, 이러한 우울증에 동반된 일상생활 기능의 저하는 인지기능의 영향에 기인하지 않는 것임을 시사된다. Objectives : Coexistence of depression is one of the important behavioral symptoms in patients with dementia of Alzheimer type. The study on the relationship between depression and cognitive abilities and /or functional abilities emerges as very important one. The aim of this study was to investigate whether depression is related to the impairment of daily activities and to certain areas of cognitive function in mild to moderate dementia of Alzheimer type. Methods : In this study, 48 patients with dementia of Alzheimer type among elderly community-residents in Kwangju, Kyunggi province, age 65 and older, were finally included. We examined their demographics and administered Korean Version of the Mini-Mental State Examination(MMSE-K). Korean Version of the Neurobehavioral Cognitive Status Examination (Korean version of NCSE), Korean Form of Geriatric Depression Scale(KGDS), Activities of Daily Living(ADL), and Instrumental Activities of Daily Living(IADL) to the subjects. We classified the subjects into two groups, dementia with and without depression on the basis of KGDS scores. The two groups were compared using χ²test and independent t-test. Results : The results show that the two groups did not differ in sex, age, education, and scores of MMSE-K. The depressed dementia group showed significantly poorer performance in bathing, one item of ADL, than the non-depressed dementia group. The depressed dementia group showed significantly more impairment in total scores of IADL and each score of three item(shopping, housework, handling finances) than the non-depressed dementia group. However, the two groups showed no significant difference in five major cognitive ability areas of Korean version of NCSE. Conclusion : These results suggest that depression in patients with dementia of Alzheimer type is highly related to the functional impairments, instrumental activities of daily living and part of activities of daily living, beyond the effects of cognitive impairments.

Free Communications : P2 ; Cannabinoid Receptors : Its Impact in Epidermal Differentiation and Possible Role in Treatment of Psoriasis

( Ji Seok Kim ),( Chan Hee Nam ),( Ji Yeon Yoo1 ),( Hyun Jung Kim ),( Se Kyoo Jeong ),( Sung Ku Ahn ),( Seung Phil Hong ) 한국피부장벽학회 2014 한국피부장벽학회지 Vol.16 No.2

Purpose: There are researches indicating that in human skin, the cannabinoid receptors exist, which take a part of endocannabinoid system. Nonetheless, the possible association of cannabinoid receptors with the pathogenesis of psoriasis has not yet been fully elucidated. Through this research, we tried to document the association between cannabinoid system, epidermal differentiation and psoriasis. Methods: Using human keratinocyte (KC), the expression of cannabinoid receptor-1 (CB1R) and -2 (CB2R) was analyzed according to the degree of differentiation. Also we examined for changes in differentiation marker of KC after application of CBR agonist. In addition, murine model applied with imiquimod to induce psoriasis symptoms was used to evaluate the effect of topical CBR agonist on inflammation and skin barrier function. Results: Compared to normal human skin, CBR expression was reduced in epidermis of psoriasis skin. Western blotting revealed the expression of both CB1R and CB2R in undifferentiated KC. The expression level of CB1R increased as the differentiation progressed in KC as with involucrin, K1 and K10. On the other hand, there was no change of CB2R in the process of differentiation. Furthermore, CB1R agonist partly increased expression of proteins associated with epidermal differentiation. Through this we could speculate that the CB system may be associated with proteins related to epidermal differentiation. Moreover, inflammation and barrier function in murine models with psoriasis symptoms were improved after 3 days-application of topical CB1R agonist. Conclusion: Cannabinoid receptors in human skin might be related to the differentiation of KC, and since its activation could improve skin barrier condition in murine psoriasis model, it can be expected to be a new therapeutic target for treatment of psoriasis.

Plasma arc light를 이용한 bracket 부착시의 전단결합강도와 파절양상의 유형

박영철,유형석,오영근,이승연 대한치과교정학회 2001 대한치과교정학회지 Vol.31 No.2

본 연구의 목적은 bracket 부착시 광조사시간을 획기적으로 감소시킬 수 있는 plasma arc licht의 임상적 유용성을 visible light 중합시의 전단결합강도와 접착파절양상과 비교해 봄으로써 평가해 보는데 있다. 사람의 상하악 소구치를 포매하여 만든 레진블럭시편에 광중합 접착제인 TransbondR를 사용하여 수종의 bracket을 각각의 조건에 따라 부착한 후 만능 물성시험기를 이용하여 전단결합강도를 측정하고, 접착파절양상을 stereoscope을 이용하여 관찰하여 다음과 같은 결과를 얻었다. 1.Plasma arc light를 이용한 수종의 bracket 접착시 metal bracket과 ceramic bracket의 전단결합강도는 임상적으로 사용하기에 충분한 값을 나타내었으며, resin bracket의 경우 다른 bracket에 비해 전단결합강도가 현저히 작은 값을 나타내었지만 임상적으로 사용이 가능한 값을 나타내었다. 2.Visible light를 이용한 metal bracket의 광중합시 광조사시 간에 따른 전단결합강도는 광조사 시 간에 따른 유의 한 차이를 보이지 않았으며, 임상적으로 사용하기에 충분한 강도를 나타내었다. 3.Plasma arc light를 이용한 수종의 bracket 접착시 접착제 잔류지수를 통해 접착파절양상을 관찰한 결과, metal bracket과 resin bracket의 경우 bracket기저면에 접착제가 반 이상 남아 있지 않은 경우가 많았으며, ceramic bracket의 경우 bracket기저면에 접착제가 반 이상 남아 있는 경우가 많았다. 4.Metal bracket의 부착시 plasma arc light를 2초간 광조사한 군과 visible light를 10초간 광조사한 군의 전단결합강도와 접착파절양상을 비교시 유의한 차이를 보이지 않았다. 6.Plasma arc light를 이용한 광중합시 광조사 거리에 따른 전단결합강도는 거리가 증가할수록 감소하였다. 이상의 실험 결과는 plasma arc light를 이용한 bracket의 접착시 전단결합강도 저하의 우려 없이 임상적으로 사용 가능함을 시사한다. The puruose of this study was to evaluate the clinical usefulness of plasma arc light which can reduce the curing time dramatically compared by shear bond strengths and failure patters of the brackens bonded with visible light in direct bracket bonding. Some kinds of brackets were bonded with the TransbondR to the human premolars which were embedded in the resin blocks according to the various conditions. After bonding, the shear bond strength was tested by Instron universal testing machine and in addition , the amount of residual adhesive remaining on the tooth after debonding was measured by the stereoscope and assessed with adhesive remnant index(ARI). The results were as follows : 1.When plasma arc light was used for bonding the brackets, the shear bond strength was clinically sufficient in both metal and ceramic brackets, but resin brackets showed significantly lower bond strength but which was clinically useful. 2.When metal brackets were bonded using visible light, there was no significant difference in shear bond strength due to the light-curing time and the bond strength was clinically sufficient. 3.When the adhesive failure patterns of brackets bonded with plasma arc light were observed by using the adhesive remnant index, the bond failure of the metal and resin bracket occurred more frequently at bracket-adhesive interface but the failure of the ceramic bracket occurred more frequently at enamel-adhesive interface. 4.There was no statistically significant difference of the shear bond strength and adhesive failure pattern between metal bracket bonded for 2 seconds by curing with plasma arc light and 10 seconds by curing with visible light. 6.When metal brackets were bonded using plasma arc light, the shear bond strength decreased as the distance from the light source increased. The above results suggest that plasma arc light can be clinically useful for bonding the brackets without fear of the decrease of the shear bond strength.

경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염

홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

인후두이상감증 환자들에서 인후두역류의 확인에 있어 음성검사의 임상적 적용

허성철,홍석중,송용진,유승주,김상윤,남순열 대한이비인후과학회 2001 대한이비인후과학회지 두경부외과학 Vol.44 No.11