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      • 균열크기 측정기법 개발에 관한 연구

        남민우,조찬희,정한섭,김홍덕,신기석 한국비파괴검사학회 2004 학술대회 논문집 Vol.- No.-

        본 연구는 증기발생기 건전성 향상기술 개발 과제 일환으로 진행중인 고리 1호기 구 증기발생기 인출 전열관을 대상으로 하는 Round Robin Test의 사전 시험을 위해 수행하였다. 균열결함에 대한 검출 및 크기측정의 기준을 설정하기 위해 SGMP Mock-Up를 제작하였고 신호수집한 Data를 증기발생기 전열관 가동중검사 업무를 수행하고 있는 와전류신호평가자들 4개조가신호평가에 참여하였으며, 그 결과를 요약 정리하였다. 본 연구에서 SGMP Mock-Up Data Crack Sizing의 목적은 고리 1호기 구 증기발생기 전열관을 대상으로 시행될 Round Robin Test 전에 결함 기구별 균열결함의 특성 이해 및 균열결함이 여러 유형의 외부 환경에서 나타나고 있을 때의 균열결함에 대한 정량적인 크기 측정값의 바람직한 모델 적용을 확인하기 위함이다. SGMP Mock-Up에 적용한 와전류검사는 Robbin 및 MRPC 검사를 포함하였다. 본 연구의 주 목적인 MRPC 데이터를 이용한 균열깊이 평가에 2개조는 위상각-깊이 분석법을 적용하여 신호평가를 수행하였고, 2개조는 위상각-깊이 분석법 이외에 진폭-깊이 평가 기법을 적용하여 SGMP Mock-Up에 대한 최적의 기법을 설정하였다.

      • 악성 혈액질환에서 성공적인 동종골수이식 후 숙주 기질 미세환경의 구축

        조상희,이제중,남찬은,최경상,정익주,이일권,김진희,박종태,김형준 대한조혈모세포이식학회 2002 대한조혈모세포이식학회지 Vol.7 No.1

        인체의 골수는 간엽모세포를 함유하고 있으며 이들은 골수미세환경의 주된 세포들로 분화가 가능하여 조혈기능을 지지한다. 본 연구에서는 성별이 다른 동종조혈모세포이식 환경에서 조혈모세포의 완전 생착을 보이고, 이식 후 1년에서 8년이 지난 11예의 재생불량성 빈혈 및 백혈병 환자들을 대상으로 하여 골수에서 MSC를 분리하고 체외 확장을 통해 배양된 MSC에서 X 염색체 탐식자를 이용한 FISH 및 microsatellite polymorphism PCR 기법으로 그 기원을 확인하였다. 그 결과 조혈모세포는 완전히 공여자 기원으로 대치되었음에도 불구하고 MSC는 모두 수여자 기원임을 알 수 있어, 동종조혈모세포이식에서 미세환경의 구축은 수여자의 자가 생산에 의한 골수 간질세포에 의한 것으로 생각된다. Background: Human bone marrow (BM) contains mesenchymal stem cells (MSC) that can differentiate into various cells of mesenchymal origin. It remains a matter of controversy whether donor-derived stromal cells are capable of engraftment following hematopoietic stem cell transplantation (HSCT) or not. Methods: To determine if donor-derived stromal cells are transferred to the recipients of allogeneic HSCT, we investigated the characterization of MSC in 11 patients 1 to 8 years after sex mis-matched allogeneic HSCT in severe aplastic anemia and leukemia. Results: All patients had complete engraftment with donor- derived stem cells as shown by detection of donor type DNA in peripheral blood mononuclear cells. Following culture, MSC showed the expression of SH2 and SH4, but none of the hematopoietic markers of CD14, CD34, or CD45. MSC which can be differentiated to osteogenic lineage showed the genotype of recipient completely using FISH or PCR analysis. Conclusion: This study confirmed that MSC isolated from recipients of allogeneic HSCT in severe aplastic anemia and leukemia are not of donor genotype despite of full hematopoietic engraftment with donor type. Donor cells did not contribute to reconstitute the marrow microenvironment.

      • 압력센서식 수위계측 시스템의 개발과 GIS에의 적용

        박찬원,박희석,남현식 강원대학교 산업기술연구소 2005 産業技術硏究 Vol.25 No.B

        This peper presents a development of the Data Logger System to transmit the outcome of the waterlevel measuring instrument using the pressure sensor by means of the CDMA network. In or order to set up the real time monitoring the waterlevel measurement system, we have designed the waterlevel sensor, communication terminal and repeater, and data logger. Furthermore, its application for the GIS(Geographical Information System) with management server system and software solutions have also developed to minimize the property damages from the flood disaster which occurs every year in the river.

      • 와전류검사에 의해 검출된 증기발생기 전열관의 균열 특성

        조찬희,남민우,김영호,양승한,이희종 한국비파괴검사학회 2004 학술대회 논문집 Vol.- No.-

        The flaws detected at the steam generator tube of the Nuclear Power Plant are the wear indications by anti-vibration bars and circumferential cracks at the top of the tubesheet. It is easy to detect and size wear indications. Also the wear indications are commonly found at the steam generator tubes. However, the steam generator tube which includes crack indication is plugged because it is very difficult to predict the growth rate and the sizing error is high. The motorized rotating pancake coil has been used for the detection of circumferential crack since it is not possible to detect using the conventional bobbin probe. This paper describes the characteristics for the circumferential crack at the steam generator tubes of the Korean Standard Nuclear Power Plants.

      • 위발성 위장관 악성림프종 환자에서 항암치료의 효과

        김찬규,신영록,김현정,배상병,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

        Purpose: The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin's lymphoma (NHL), which is increasing in incidence, but there is no established optimal treatment modality. Thus, this study was investigated the clinicohistologic feature, the therapeutic modalities, and the prognosis for GI-NHL, as well as the factors affecting it. Methods: We retrospectively analyzed 45 patients who had been diagnosed as having GI-NHL and had been followed up from July 1994 to February 2005 at Soonchunhyang University Hospital. The patients were divided into groups according to the site of origin and to various other features, and the survivals of the various groups were compared. The modified Ann Arbor system and WHO classification were adopted for staging and histopathologic classification, respectively. Results: GI-NHL of the stomach, small bowel, ileocecal region, and colon occurred in 28 patients (62.2%), 5 patients (11.1%), 3 patients (6.7%), and 8 patients (17.8%), respectively, In one patient, the entire gastrointestinal tract was diffusely involved. The median age of patients was b5 years (25~78 years), and male-to-female ratio was 1:1.1. Fourteen patients were in stage Ⅰ, 24 in stage Ⅱ, 4 in stage Ⅲ, and 3 in stage Ⅳ. Surgical resection was performed in 19 patients, and combination chemotherapy was performed in 43 patients. Surgical resection only was performed in 4 patients, Chemotherapy only was performed in 26 patients. The expected overall 5 year survival of 45 patients was 39.6%, and there was a significant survival difference between the stages, but between sites of origin (p=0.842). The most important factors influencing the survival was the stage and other factors were not significant. Conclusion: The stomach was the most common site of GI-NHL. Most GI-NHL were localized Stage was the most important prognostic factor. However, Prospective randomized studies are needed to approve the therapeutic modality.

      • 마이크로파에 의한 Li₂O-2SiO₂글라스의 핵생성 및 결정 성장 거동

        박희찬,박성수,김경태,김진남 釜山大學校生産技術硏究所 1998 生産技術硏究所論文集 Vol.55 No.-

        Li₂O-SiO₂계 글라스를 재래식 열원과 마이크로파 열원으로 가열했을 때, 핵생성 및 결정화 거동을 비교 조사하였다. 전자주사현미경 분석, X선 회절 분석 및 시차열분석을 통하여 결과를 분석하였다. 재래식 열원과 마이크로파 열원으로 가열된 시편들의 핵생성 및 결정화 거동이 매우 상이하였다. 마이크로파가 시편내의 핵 생성을 억제시켰지만, 결정 성장은 축진시켰다고 추측된다. A comparison of nucleation and crystallization of Li₂O-SiO₂glass system under between the conventional and microwave heating was investigated. Scanning electron microscopy, X-ray diffractometry, and differential thermal analysis were used to evaluate the results. Nucleation and crystallization behaviors under the microwave heating appeared largely different from under the conventional heating. It was assumed that microwaves inhibitied nucleation, but accelerted crystal growth.

      • 폐석재와 석분을 사용한 식생블럭 제품 개발

        성찬용,류능환,연규석,윤준노,김영익,남기성,노경희,박일순 강원대학교 부설 석재복합신소재 제품연구센터 2002 석재연 논문집 Vol.7 No.-

        본 연구는 폐석재와 석분을 사용하여 친환경적인 식생블럭 제품을 개발하기 위하여 폐석재의 입경과 석분의 첨가량을 각각 3종류씩 총 9종류의 식생블럭에 대하여 단위중량, 공극율, 투수량, 압축강도, 쪼갬인장강도, 휨강도, 내산성, 알카리농도에 대하여 구명하였다. 단위중량, 강도, 내산성은 골재의 입경이 작을수록 석분의 혼입량이 많을수록 크게 나타났으며, 공극율과 투수량은 작게 나타났다. 강도는 중성화 처리 유무에 따라 4∼5% 정도의 미소한 차이가 나타났다. 알카리 농도는 중성화 약품처리, 수중용출, 야외폭로 순으로 효과가 크게 나타났으며, 이는 식생블럭의 중성화 방법 선택에 매우 중요한 내용이라 할 수 있다. 또한, 식생상태는 공극율과 골재의 입경이 큰 식생블럭이 생육에 유리한 것으로 나타났다. This study was performed to develop the environment-friendly plantable block and to evaluate unit weight, void ratio, permeability, strength, acid-resistance and value of pH by the change of the grading of waste stone and the addition amount of stone dust. The unit weight, strength, acid-resistance is increased with small size of waste stone with increase of the addition amount of stone dust. But, the void ratio and permeability is decreased. The strength of neutral plantable block is decreased approximately 4-5% than that of the normal plantable block. The decreased effect of pH increased in order to neutral treatment, underwater leaching and field exposure. It is very important contents in neutral method selection of plantable block. Also, the planting state is grown rapidly with increase of the void ratio and of the waste stone size, approximately.

      • 횡문근 융해증의 Tc-99m Methylene Diphosphonate 신티그라피 소견

        한창진,박찬희,윤석남,배문선,김수지,신규설 아주대학교 1997 아주의학 Vol.2 No.2

        Many causes of rhabdomyolysis have been reported in the literature. Technetium-99m methylene dipho-sphonate (Tc-99m MDP) bone scintigraphy is considered to be the most sensitive and effective modality in defining the extents of disease involvement and follow-up of patients with rhabdomyolysis. In this paper, we reviewed two cases of generalized rhabdomyolysis related to seizure activities and two cases of localized rhabdomyolysis related to an excessive exercise. In addition other causes of rhabdomyolysis and possible mechanisrns of Tc-99m MDP uptake are discussed briefly.

      • 국제 경기를 통한 스포츠 산업의 활성화 방안

        김인형,최동일,남희은,이근모,김찬룡 釜山大學校 附設 體育科學硏究所 1998 體育科學硏究所 論文集 Vol.14 No.-

        This study was mainly focused on the relationship between sports industry and international games. According to the category of both sports information ·service industry and sports technology industry. The way of activating sports industry by international games is proposed as follows; 1. Sports information · service industry 1) Sports Event (1) Expending the inducement of sports event sponsored by domestic international enterprises. (2) Improving image of enterprise by activating character industry. (3) Elevating the mood of international games by pre-event and post-event. (4) Attracting tourist during games session by opening various cultural and artistic events. 2. Media (1) Establishment of Media facilities such as international broadcasting center or media center. (2) Providing best media services by digitalizing every kind of broadcasts. (3) Using aggressive internet advertisement of game's information, cultural events, tourism, and etc. 3. Sports Event Tourism (1) Providing sports event package tourism. (2) Rehabilitating accomodation and convenience facility at the level of advanced country. (3) Building sports theme complex well international sports heros are taken as theme. (4) Building sports mall well every sports-related businesses can be a solved as one-stop service. 2. Sports technology industry 1) Sports Facility (1) Founding the organization of which mission is to induce long-term fund for building and repairing sports facilities. (2) Acquiring economic benefit by selling the right to call sports facilities after company names. (3) Building all weather and multi-purpose sports facilities and practically using after games. 2) Sports Goods (1) Following consumers' demand for design and colors of goods. (2) Developing marketing strategy by opening sports goods expo. (3) Reinforcing the information network among company groups. (4) Acquiring government support for developing sports goods marketers. (5) Developing new kind of leisure goods.

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