사립체 DNA 뉴클레오타이드 3243 A→G 돌연변이 [MTTL1^*MELAS3243G]에 의한 MELAS 증후군

박기형,김승현,이영주,김희태,김주한,김명호,박성섭 대한신경과학회 1998 대한신경과학회지 Vol.16 No.4

금단 증상을 동반한 헤로인 의존 1례

남궁기,한승진 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.2

저자들은 약 1년간의 헤로인 의존상태에서 갑작스런 약물 투여 중단 후 나타난 헤로인 금단증산을 가진 27세 여자환자를 경험하였다. 환자는 약물투여 중단 후 의식의 혼탁, 혼란, 이자극성, 불안, 초조, 불면, 오심, 구토, 복통, 사지통, 동공의 수축 등의 전형적인 헤로인 금단증상을 보였다. 헤로인은 미국과 동남아시아를 비롯한 세계각지에서 이미 흔한 남용약물로 사용되고 있으나, 아직 우리 나라에서는 흔히 경험할 수 없는 증례이므로 이를 문헌고찰과 함께 보고한다. The authors experience 27 year old female patient with heroin dependence accompanied by the typical heroin withdrawal symptoms such as confusion, irritability, anxiety, agitation, insomnia, nausea, vomiting, abdominal colicky pain, pain on both extremities and pupil constriction. Although heroin is one of the most popular illicit drug in the world, this is not the case in Korea. So we reported this case with literature review.

상악동에 발생한 거대한 Cholesterol 육아종 1례

김승찬,박형욱,김용기,나한조,도남용 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.16 No.1

The cholesterol granuloma is not a specific clinical or pathologic entity but merely a term used to describe a tissue response to cholesterol crystal. The cholesterol granuloma in paranasal sinuses is rare disease. Recently the authors had experienced a case of huge cholesterol granuloma, which involved the right maxillary sinus. The cholesterol granuloma was removed successfully by mean of enucleation through the Caldwell-Luc approach. So, we report a case with brief review of the literature.

RTT에 가중치를 적용한 Snoop 알고리즘 성능 개선

금승한,김태훈,박혜련,이기현 明知大學校 産業技術硏究所 2006 産業技術硏究所論文集 Vol.25 No.-

In this paper, we propose the enhanced algorithm to cope with the issue which shows that short connections lend to lose to long connections in their competition for bandwidth in the wireless internet environment. This is because TCP is originally evolving in wired environment and short connections don’t know the traffic information, and therefore they are doomed to be less competitive due to the conservative nature of the TCP congestion control algorithm. Inspired by the Snoop algorithm, we proposed an enhanced algorithm to give an improved performance by adapting the weight in RTT estimation of the Snoop algorithm, so that the fairness is applied in the wirelss internet environment.

Polysulfide 前處理에 의한 Cyanide 含有廢水의 活性汚泥處理

金承鶴,李武康,韓基白 慶星大學校 環境問題硏究所 1992 環境硏報 Vol.2 No.1

The objective of this study was performed in order to obtain the changing efficiency of SCN- according to and reaction time. For that reason, the polysulfide was added to the cyanide wastewater in a fixed weight ratio. Herewith the design parameter was determined for the synthetic wastewater containing 300㎎/ℓof SCN- and was compared substrate removal constant(k) with adsorption reaction constant(k₁k₂) by adsorption equilibrium eqtion. The changing rate of CN- to SCN- was found to be pH 10, pH 12 for 90∼95 percent within 3 hours. On other hand, was found to be pH 7 for 60∼65 perdent due to the Polysulfide precipitating. On the occasion of 10, after the reaction time proceeded 3 hours, pH of bulk solution was varied from 10 to 7. But practically changing of SCN concentration was not significant. Treatment of the synthetic wastewater containing 300㎎/ℓof SCN- at 20±1℃ with the Hydraulic retention tin of 6 to 18 and MLVSS concentration of 3050 to 3590㎎/ℓgave 94.2∼96.5 percent in substrate removal efficiencies as COD . The design parameters of k, Y, ke, Vmax and Km were determined to 0.0247 d-1, 0.2119, 0.0561 d-1, 4 d-1, and 153.96㎎/ℓ. In adsorption teste using acclimated sludge, adsorption removal rate was 0.5476㎎/㎎ MLVSS. day at 314㎎/ℓ initial SCN- concentration and was 0.3045㎎/㎎ MLVSS·day at 576㎎/ℓ of initial SCN- concentration. It was adapted adsorption equilibrium equation for substrate removal by the activated sludege. In the results, Freudlich's adsorption reaction constant, k₁ was 0.0273 day-1 and n₁was 0.840 and Katz's adsorption reaction constant, k₂ was 0.0287 day-1 and n₂was 0.839. These values were similar in comparison with the substrate removal constant(k=0.247).

白鼠感染 肝吸蟲의 幼蟲 및 成蟲에 대한 국산 praziquantel(Distocide^(�))의 殺蟲效果

林漢鍾,李駿商,朱炅煥,朴升圭,嚴基善,呂煥旭 최신의학사 1985 最新醫學 Vol.28 No.7

Master Gardener 프로그램 특성에 관한 연구 : Virginia Cooperative Extension을 중심으로 with Special Reference to the Virginia Cooperative Extension

곽혜란,한승원,이종석,김신기 한국화훼연구회 2001 화훼연구 Vol.9 No.1

The Master Gardener(MG) program is one of representative outreach program of cooperative extension at land grant Universities in U.S.A. The purpose of MG programs are primarily focused on educating community and people who want to join gardening project. MGs are valuable resources as volunteer-educators teaching environmental horticulture, increasing life quality through horticulture, community landscaping, school gardening, nutrition problems and horticultural therapy for the common-wealth or benefit of their community. MG educational programs and volunteer internships are needed to get and maintain MG title and they follow the policies and philosophies of cooperative extension. MG programs present lots of benefits by enlarge boundaries of horticulture and offer the practical educational services. To extend and activate further the value of horticulture, the MG programs should be introduced in Korea soon. MGs are regarded as new managers or primary leaders for educating horticulture, landscaping for community because of their knowledge and eagerness to help the people's advancement.

알렉시딘과 차아염소산나트륨의 화학적 상호반응 후 mass spectrometry를 이용한 파라클로로아닐린의검출 분석

김현식,한승현,오소람,임상민,구유,금기연 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.4

근관세척제인 NaOCl과 CHX를 병행 사용하는 경우 적갈색의 발암물질로 알려진 PCA가 생성된다. 본 연구의 목적은 CHX와 유사한 buigunide 계통의 소독제 인 ALX을 NaOCl 과 흔합 반응 시 PCA가 생성되 는지 여부를 mass spectrometry를 이용하여 평가하고자 하였다. 대조군으로는 4% NaOCl 용액과 2% CHX의 혼합용액, 0.5%PCA 용액, 및 1%ALX 용액을 사용하였고 실험군으로는 5가지 농도(1%, 0.5%, 0.25%, 0.125%, 0.0625%)의 ALX 용액과 4% NaOCl의 흔합용액을 질량분석기를 이용하여 mole-cular peak를 분석한 결과 ALX과 NaOCl의 혼합물에서는 PCA(m/w=128)로 보이는 128 피크가 관찰되지 않았다. 또한 용액의 색 변화에서도 ALX이 농도가 높을수록 열은 노랑색을 띄었으나 농도가 낮아질수록 흰색으로 관찰되었으며 어떠한 침전물의 형성도 보이지 않았다. Recent studies demonstrated that the combination of chlorhexidine (CHX) and sodium hypochlorite (NaOCl) resulted in the formation of a precipitate, para-chloroaniline (PCA). Alexdidine (ALX) is a kind of biguanides like CHX, and has stronger detoxification effect against the bacterial virulence factors such as lipoteichoic acid and lipopolysacchardide compared with CHX. The purpose of this study was to determine whether PCA was formed after chemical interaction between ALX and NaOCl using mass spectrometry. Mass spectrometry was performed for the mixture of five different concentrations of ALX (1, 0.5, 0.25, 0.125, 0.0625%) and 4% NaOCl. Results showed that the peak of PCA was not detected in mixed solu tions of ALX and NaOCl in mass spectrometry analysis. The color of mixed solution of ALX and NaOCl after chemical interaction was light yellow to white, but there wasn't any precipitate found.

TSP에서의 유전자 알고리즘

이강구,한승기 충북대학교컴퓨터과학연구소 1994 컴퓨터과학연구 Vol.2 No.1

본 연구에서는 TSP에 유전자 알고리즘을 적용하여 최단 경로를 찾아내는 방법에 대해서 조사하였다. 유전자 알고리즘을 TSP에 적용하기 위해서는 N개의 도시 데이터에 적절한 돌연변이, 교차 및 전위 연산자를 도입하여야 한다. 최근에 많은 관심을 끌고 있는 Precedence 행렬을 이용한 교차 연산인 UNION 연산자는 기존의 연산자보다 훨씬 쉽게 최적의 경로로 접근함을 보였다. 그러나 이 방법은 Precedence 행렬 계산 때문에 메모리가 많이 필요하고 매 단계마다 걸리는 계산시간이 길어지는 단점이 있다. 본 연구에서는 UNION 연산자를 기존의 방법처럼 N개의 도시에 대한 연산으로 바꾸어 주었다. 그 결과 매 단계마다 걸리는 시간도 줄어들고, 경로도 최적의 경로로 쉽게 접근함을 보였다.

곰팡이에서 분리한 Helicobacter pylori 항균물질의 분리 및 구조규명

남궁준,연승우,백남수,김태한,김영호,김창진,김기원 충남대학교 약학대학 의약품개발연구소 1998 藥學論文集 Vol.14 No.-

Helicobacter pylori is a Gram-negative bacterium which causes chronic gastritis and is associated with gastric ulcer, duodenal ulcer and gastric carcinoma. In the process of screening of antibacterial activities against H. pylori from soil microorgani는, fungus No. 60686 was isolated. After fementaion of No. 60686, the antibacterial compound was isolated, purified and followed by extraction of mycelium with orgainic solvents, acetone and ethyl acetate, through silica gel chromatography, LH-20 gel chromatography and HPLC. As a result of the structural analyses of the compound by IR, ^1H- and ^13C-NMR, FAB/Mass spectrophotomer, the compound having the antimicrobial activity was idenfitied as chaetoglobosin A (C_32H_36N_2O_5), a cytochalasan derivative. The antimicrobial activity of chaetoglobosin A was tested against Gram-positive and negative bacteria by paper disk method. Among the test strains of 9 Gram-positive bacteria and 18 Gram-negative bacteria containing 4 H. pylori strains, the growth of 4 H. pylori strains and 3 S. aureus strains (SG 511, 285 and 503) was only inhibited by chaetoglobosin A. Also it was shown that its growth inhibition against H. pylori strains was stronger than that against S. aureus strains at the treatment of the same concentration. Therefore it was concluded that chaetoglobosin A has a specific growth inhibition against H. pylori of the tested bacteria.