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      • 소傳梁性 角結膜炎(IBK)菌의 菌體不活化 試驗 vaccine의 免疫效果

        石瑚峰 단국대학교 1988 論文集 Vol.22 No.-

        In studies to determine whether vaccination with one strain(1843) of β-hemolytic Moraxella bovis would protect against challenge with virulent homologous strain, calves were intramuscularly inocularly 3 times with formalin-killed M. bovis with 14 days between inoculations. All of the calves became infected after challenge exposure. The mean rates and duration of the bacterial infection were less (P<0.01) in the vaccinated calves (21.3% & 16.2 days) than in the nonvaccinated controls (65.3% & 29.8 days). Signs of IBK developed in 5(100%) of the controls and 4(80%) of the vaccinated calves. The mean disease rates and incubation day of IBK signs less (P<0.01) in the vaccinated calves (11% & 15.9 days) than in the nonvaccinated control (51.7% & 30.5 days). All calves developed detectable antibody by GDPT after the 3rd dose of vaccine and the antibody persisted in the calves for 8~10 weeks after challenge exposure. These results indicate that formalin-killed culture is effective for immunizing calves.

      • 돼지 난포란의 체외 성숙시 성선 자극 호르몬의 첨자가 난자 성숙에 미치는 영향

        석호봉,남상규 단국대학교 1998 論文集 Vol.32 No.-

        This study was carried out to investigate the effects of gonadotropins added during in vitro maturation of porcine oocytes. The follicular oocytes were cultured in TCM-199 medium and Ham's F-10 medium containing different combination of gonadotropins. The results of emerging rate of germinal vesicle(GV), germinal vesicle breakdown(GVBD), metaphase-I(M-I) and metaphase-II(M-II) stages by 1% aceto-orcein staining and Hoechst 33342 DNA labelling were as follows. The oocyte maturity were observed in the emerging rate of GVBD and M-II stages after cultures in media hormones added. The optimal concentrations for oocytes maturity with a single treatment of FSH, hCG and LH were indicated to 0.5㎍/mi, 2IU/ml and 2IU/ml, respectively. The rates of GVBD and M-II stages were showed higher in that order LH(62.7%), hCG(51.7%) and FSH(35.3%). When the oocytes were matured for 44hrs in the medium containing of FSH+hCG, FSH+LH, hCG+LH and each treatment of the hormones, the maturity rates were figured in 70%, 63.3%, 58.6% and same 60% for each. Finally, in comparison wth the oocytes maturity by the emerging rate between TCM-199 medium and Ham's F-10, the former (49.5%) is insignificantly a similar tendency to the latter(48.5%). These results demonstrate that the addition of gonadotropins to the culture medium has a significant influence on the rate at which porcine oocytes undergo maturation.

      • 분말충진방법과 가공정도에 따른 Ag/BSCCO 초전도선재의 특성

        지봉기,김태우,김정호,김중석,주진호 成均館大學校 科學技術硏究所 1998 論文集 Vol.49 No.1

        We evaluated the effects of processing variables on interface irregularity. microstructure. and resultant Jc of BSCCC superconductor tape. For the tapes made by PIT technique. the degree of interface irregularity was varied with powder packing methods and forming process variables. It was observed that the degree of interface irregularity of the tape by CIP method was more reduced. compared to that of the tape by ram method. In addition. the degree of interface irregularity was promoted with decreasing the dimension of tape during forming process. As the dimension of wire/tape were changed from diameter of 3.25mm to thickness of 200㎛ during forming process. Jc value was observed to be increased by 10 times. It was likely that the improvenment of Jc was mainly result from the enhanced texturing of 2223 grain. Microstructural investigation showed the degree of texturing was degraded by the existence of both second phases and interface irregularity. If the interface was flat, larger grain size and better texturing near interface were developed compared to those inside superconducting core, The improvements of microstructure near interface may be result of reaction between Ag and superconductor phase.

      • KCI등재

        출생순위와 정신장애

        석재호,안석철,손봉기 大韓神經精神醫學會 1978 신경정신의학 Vol.17 No.2

        There have been many reports which dealt with the matter of incidence of schizophrenia, controlled by family size and sibling order. They got no uniform result but many of them suggested a possible relation between the schizophrenic incidence and the sibling order. Meanwhile the family size is getting smaller. Anticipation of this leads us to deal with the problem of mental hygiene in the small sized family. So the authors have chosen the mental patients who have two siblings, in the O.P.D. and the ward of Department of Neuropsychiatry of Han-Gang Sacred Heart Hospital from September 1976 to November 1977 to see the incidence of psychoses and neuroses among three siblings. The authors could sample 124 cases of psychotic and neurotic patients excluding patients with brain syndromes and 60 cases of organic brain syndromes, the control group. The results were as follows: 1. Among 29 psychotics, 12 were the first born, 7 the second born and 10 the third born. Among 95 neurotics, 30 cases were the first born, 37 the second born and 28 the third born. No significant difference was noted among these features. 2. In the subgroups of one son and two daughters, 3 brothers, and 3 sisters, no siginificant relationship in incidnece of mental disorder could be found. 3. In the subgroups of two sons and one daughter, the incidence of neurosis was significantly high in females. 4. In the group of organic brain syndromes, there was no significant difference in the incidence of psychosis and neurosis among different sibling orders.

      • KCI등재

        가시오가피의 부위별 물 추출물이 흰쥐의 혈관이완반응에 미치는 영향

        姜奉錫,金亨煥,安德均,崔湖榮 대한본초학회 2001 大韓本草學會誌 Vol.16 No.2

        In this study we have examined the actions of water extract of Eleutherococus senticosus (Rupr. et Maxim.) Maxim. (ESH), Stem, Root bark (RB) and Root xylem (RX) in isolated thoracic and abdominal aorta assay. To compare the vasodilation effect, put. ESH, Stem, RB and RX into them which vessels were precontracted by 5-hydroxytryptamine (5-HT). We found out the thoracic aorta segments were responded to ESH with a dose-dependent vasodilation. The 5-HT induced contraction at 10-4M were relaxed after addition of the 2.0 ㎎/㎖ ESH as 32.1% (Stem), 34.9% (RX) and 87.2% (RB). The 5-HT induced vasocontraction at 10^-4M were vasodilated such as 87.2% in thoracic aorta and 89.0% in abdominal aorta with 2.0㎎/㎖ ESH. Addition of 2.0㎎/㎖ ESH in thoracic aorta which was precontracted by the 5-HT at 10-4M were come out differently 0% (water fraction), 53.8% (butanol fraction) and 96.6% (ethyl acetate fraction). The 5-HT induced contraction at 10-4M with and without endothelium were inhibited by 87.2% and 87.8% after addition of the ESH (2.0 ㎎/㎖). In conclusion, ESH-induced relaxation in the isolated rat thoracic aorta and abdominal aorta were come out be dose-dependent relaxation, and ESH's ethyl acetate fraction was showed the potent vasodilation effect.

      • KCI등재후보
      • 水産專門大學 漁業科 敎育課程 開發硏究

        裵錫悌,宋之浩,李吉來,鄭興基,洪聖根,趙鳳坤,朴種洙 군산대학교 1983 群山水産專門大學 硏究報告 Vol.17 No.1

        In order to develop the curriculum of the fishery department in the fisheries Jr. college, We have collected and analyzed the domistic and foreign data adquated to the fishey department under the international trend, also we gathered the opinion from the inquiring paper investigation and consultation to the industrial field, concerned college and graduate during the 6 month from September 1982. The fishery department curriculum in fisheries Jr. college will be industrialized with the concerned technics and knowledge in relation to speciality of maritime affairs. Accordingly, we have developed the adquate curriculum which is practical and can be cultivated the technician to adopt in the industrial society.

      • 숯첨가 사료투여가 넙치의 면역반응에 미치는 영향

        권문경,이윤호,박상언,김봉석,박수일 한국어병학회 2002 한국어병학회지 Vol.15 No.1

        숯첨가 사료 투여가 넙치에 미치는 영향을 알기 위하여, 넙치에 숯 1%, 3%, 5% 첨가사료를 8주간 투여하면서 성장, 혈액성분, 비특이적면역능을 분석하였으며 어병세균인 Edwardsiella tarda 균의 공격 시험에 대한 방어능을 조사하였다. 숯 첨가 사료 투여는 넙치의 성장과 라이소자임 활성에서는 유의적인 차이를 나타내지 못했지만, 5% 숯첨가구에서 혈액 중의 total protein과 cholesterol의 농도가 대조구에 비하여 낮게 나타났다. 그리고, 숯 3% 첨가구에서 두신 식세포의 활성 및 병원성 세균인 E. tarda에 대한 방어능도 가장 높게 나타났다. The charcoal effects on the immune responses of flounder, Paralichthys olivaceus were studied. Fish were fed an experimental diet supplemented with 1%, 3% or 5% of charcoal to a commercial diet. Several factors such as weight gain, hematological parameters, nonspecific immune responses and resistance against Edwardsiella tarda were evaluated 4 and 8 weeks after the administraion. The changes of body weight and lysozyme activities were not signigicant among tested groups. But cholesterol and total protein concentration in the blood were significantly lower in the 5% supplemented group than in the control. The production of superoxide by macrophage from the head kidney, examined by NBT reduction, was significantly higher in the 3% charcoal supplemented groups than in the control. The survival rate after an artificial challenge with 1×10^exp(7) cells of E. tarda per fish was significantly the highest in the 3% charcoal supplemented group.

      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

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