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      • KCI등재

        Antioxidant and anti-inflammatory activity of Heritiera fomes (Buch.-Ham), a mangrove plant of the Sundarbans

        Islam Md. Emdadul,Islam Kazi Mohammed Didarul,Billah Md. Morsaline,Biswas Rana,Sohrab Md. Hossain,Rahman S. M. Mahbubur 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.2

        The antioxidant and anti-inflammatory potential of Heritiera fomes ethanolic extract was evaluated.Query Ethanolic extraction of dried and grinded plant leaves and bark was performed. Antioxidant activity was evaluated by 1, 1-diphenyl-2-picryl-hydrazil (DPPH) free radical scavenging assay, ferric reducing antioxidant power (FRAP) and β-carotene bleaching inhibition assay. Total phenolic and flavonoid content were also determined. Anti-inflammatory activity was evaluated by in vitro human RBC membrane stabilizing assay and in vivo mice paw edema test. Ethanolic bark and leaf extracts of H. fomes (S1 and S2, respectively) showed significant scavenging effect on DPPH scavenging 68.51 µg/ml for S1 and 108.64 µg/ml for S2. Potent reduction potential (FRAP) was observed in S1 (83.75 mM of ferrous equivalent) while the FRAP of standard ascorbic acid was found 86.66 μM of ferrous equivalent. S1 also exhibited 87.43% β-carotene bleaching inhibition as comparable to standard butylated hydroxytoluene with 98.85% inhibition. Substantial phenolic and flavonoid content was also observed in S1 (136.83 μg gallic acid equivalent/g of extract and 76.67 μg quercetin equivalent/g of extract, respectively). S1 could provide 61.73% and 53.27% protection of RBC membrane in hypotonicity and heat induced lysis of RBC, respectively while the standard diclofenac sodium provided 91.66% and 86.66% protection, respectively. Furthermore, 44.16% reduction in mice paw edema at 40 μg/kg bw concentration was observed in S1 as compared to standard indomethacine (53.54% in 10 μg/kg bw concentration). The results revealed that the bark extract (S1) of H. fomes possesses significant antioxidant and anti-inflammatory activity.

      • KCI등재

        Antioxidant and antibacterial activity of three herbs belonging to Zingiber genus of Bangladesh

        Afiya Aunjum,Rana Biswas,Tauhidur Rahman Nurunnabi,S.M. Mahbubur Rahman,Md. Morsaline Billah,Md. Emdadul Islam,Kazi Mohammed Didarul Islam 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.3

        Apart from boosting flavor, herbs and spices are also known for their preservative, antioxidant, antimicrobial and other medicinal properties. Bioactive metabolites with aspiring prospect have guided the present study to screen for antibacterial and antioxidant activity of three Zingiber plants available in Bangladesh. For that purpose, rhizomes of Zingiber officinale, Z. montanum and Z. zerumbet were extracted with ethanol as solvent system for bioactivity analysis. Antioxidant activity was assessed by employing DPPH free radical scavenging assay, reducing power assay and ferric reducing antioxidant power (FRAP) assay. Z. officinale extract demonstrated the highest free radical scavenging activity ( IC50: 43.65 μg/ml), reducing power ( EC50: 189.026 μg/ml) and FRAP value (137.18 ± 0.116 μM Fe(II)/100 μg dry weight of extract). Moreover, total phenolic, flavonoid and tannin content were determined which significantly correlated (Pearson correlation) with the antioxidant activities. For the evaluation of antibacterial activity, zone of inhibition (ZOI) was measured by disc diffusion bioassay against four Gram positive bacteria Bacillus megaterium, Staphylococcus aureus, Micrococcus spp., and S. epidermidis as well as ten Gram negative bacteria Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, S. paratyphi, Vibrio cholera, Shigella dysenteriae, S. flexneri, Proteus spp., Mycobacterium spp., and Campylobacter spp. Z. montanum extract exhibited significant activity against E. coli (13.67 ± 0.577 mm ZOI) and Micrococcus spp. (14.33 ± 0.763 mm ZOI) if compared to standard erythromycin with ZOI 15.33 ± 0.577 mm and 15.67 ± 0.577 mm, respectively. Furthermore, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Z. montanum extract were determined against B. megaterium, Micrococcus spp., E. coli and S. paratyphi. Thus, Z. officinale and Z. montanum extracts could be utilized as source and template for the synthesis of potential drugs and food supplements as well.

      • KCI등재

        A green microextraction method in a narrow glass column for copper in artificial saliva extract of smokeless tobacco products

        Sadaf S. Arain,Tasneem G. Kazi,Hassan I. Afridi,Naeemullah,Kapil D. Brahman,Muhammad B. Arain,Abdul H. Panhwar,Mariam S. Arain,Shahnawaz Baloch 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.34 No.-

        A green non-dispersive ionic liquid based microextraction (ND-ILmE) method was proposed for thepreconcentration of trace levels of copper (Cu2+) in artificial saliva extract (ASE) of smokeless tobaccoproducts (SLT). A 100 cm long, narrow glass column containing aqueous solution of Cu/ASE was used toincrease phase transfer ratio by providing more contact area between two medium, which drasticallyimprove the recovery of Cu-PAN complex into ionic liquid 1-butyl-3-methylimidazolium hexafluor-ophosphate [C4mim][PF6]. At optimum experimental conditions, the detection limit and theenhancement factor were found to be 0.042 mg L 1 and 85, respectively. This method was successfullyapplied to real samples.

      • KCI등재

        Development of early flowering, short life-spanned jute (Corchorus spp.) mutant via ethyl methane sulfonate mutagenesis

        Hossen Quazi Md. Mosaddeque,Rahman S. M. Badier,Rahman Md. Nazibur,Sarker Muhammad Delwar Hossain,Moniruzzaman Md.,Tareq Md. Zablul,Sadat Md. Abu,Arafat Kazi Md. Yasin,Jahan Md. Sarwar,Haque Md. Samiu 한국작물학회 2022 Journal of crop science and biotechnology Vol.25 No.4

        Polyethene is a global environmental threat, whereas jute (Corchorus spp.) fber is biodegradable, eco-friendly and can be used as a substitute for polyethene. Jute is a short-day plant and cultivated in March to July in Indian subcontinent for bast fber production. This season-bound cultivation nature hampers continuous supply of bast fber in the industry. In addition, its long cultivation period creates difculties to accommodate other high-value crops. To address these issues, a short life span (early fowering) jute genotype is extremely felt in jute growing areas of the world. But, unfortunately such variety has not been developed yet through both conventional and biotechnological approach. Accordingly, we adopted chemical mutagenesis by establishing LD50 (Lethal Dose) of EMS (Ethyl Methane Sulfonate) at 150 mM with 4h’ incubation for Capsularis jute seed. A novel mutant was found named—Komola, which showed a shorter lifespan than its ancestor by fowering at 70 days instead of 120 days. In addition, the mutant's stem and petiole was coppery-red instead of green. Molecular analysis revealed four SNPs in PMIR1 (Plastid Movement Impaired 1 Related 1) and two clade deletions in ELF3 (Early Flowering 3) genes from stable M4 generation. Histochemical and biochemical analyses explained this genotype’s lower content of lignin. This mutant could be used as future breeding material for the development of year-round cultivable jute genotype along with ofer up accommodation of other high-value agricultural crops in cropping pattern with a good source of year-round supply of bast fber to the industry

      • SCIESCOPUS

        Computational Modelling of Droplet Dynamics Behaviour in Polymer Electrolyte Membrane Fuel Cells: A Review

        Yong, K.W.,Ganesan, P.B.,Kazi, S.N.,Ramesh, S.,Sandaran, S.C. The Korean Electrochemical Society 2019 Journal of electrochemical science and technology Vol.10 No.4

        Polymer Electrolyte Membrane Fuel Cells (PEMFC) is one of the leading advanced energy conversion technology for the use in transport. It generates water droplets through the catalytic processes and dispenses the water through the gas-flowed microchannels. The droplets in the dispensing microchannel experience g-forces from different directions during the operation in transport. Therefore, this paper reviews the computational modelling topics of droplet dynamics behaviour specifically for three categories, i.e. (i) the droplet sliding down a surface, (ii) the droplet moving in a gas-flowed microchannel, and (iii) the droplet jumping upon coalescence on superhydrophobic surface; in particular for the parameters like hydrophobicity surfaces, droplet sizes, numerical methods, channel sizes, wall conditions, popular references and boundary conditions.

      • KCI등재

        The Effects of Hydrophobicity and Drainage Velocity on Water Retention Behavior in Porous Media: A Computational Study

        K. W. Yong,P. B. Ganesan,E. Hamidi,S. N. Kazi,S. Ramesh 대한설비공학회 2020 International Journal Of Air-Conditioning and Refr Vol.28 No.4

        The present study investigates the water retention behavior in two different types of porous media, i.e., porous metal — a type of metallic foam and ideal geometry. The present study uses computational fluid dynamics (CFD) to model a decreasing water level in a reservoir consisting of a stationary porous medium beneath the water surface at initial stage. It mimics the setup of dynamics dip-testing which measures the amount of retained water for different types of fins-tubes heat exchangers. The study varies parameters like static contact angle (θ s)and drainage velocity (U). The literature review summarizes the unique water retention behaviors for different types of heat exchangers and the findings of the present study. Furthermore, the present study proposed new parameters for evaluating the structural variations in porous metal that explains the water saturation distribution in detail. The evaluation method could provide an insightful idea for performing the quality control check on metallic foam.

      • An Analytical Approach to Direct Torque and Flux Control of Interior Permanent Magnet Synchronous Machine for Deep Field Weakening Without Using Pre-calculated Lookup Tables

        S M Showybul Islam Shakib,D. Xiao,R. Dutta,Kazi Saiful Alam,Ilham Osman,M. F. Rahman 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

        This paper presents an analytic approach to direct torque and flux controller (DTFC) for Interior permanent magnet synchronous machine (IPMSM) which includes deep flux weakening. Unlike the conventional lookup tables (LUTs) based DTFC, this paper proposes a direct mathematical calculation approach for the stator flux reference as well as the torque limit in field weakening (FW) and maximum-torque-per-voltage (MTPV) regions. The proposed method will thus allow flexibility of using online estimated machine parameters directly for an optimized IPMSM drive. This study also explores the voltage and current limit trajectories on a torque-flux linkage plane to operate the machine in deep field weakening. It incorporates maximumtorque- per-ampere (MTPA), FW, and MTPV trajectories control under voltage and current constraints. Experimental results are shown to verify the effectiveness of the proposed algorithm.

      • SCISCIESCOPUS

        ON THE POSSIBLE MECHANISMS OF TWO GROUND-LEVEL ENHANCEMENT EVENTS

        Firoz, Kazi A.,Moon, Y.-J.,Park, S.-H.,Kudela, K.,Islam, Jamal N.,Dorman, Lev I. IOP Publishing 2011 The Astrophysical journal Vol.743 No.2

        <P>We have carried out a case study on the possible mechanism of ground-level enhancement (GLE) occurrence. For this, we have considered two GLE events (GLE69 and GLE70) and scrutinized their relationships with simultaneous soft/hard X-rays as well as solar energetic particle (SEP) fluxes of different energy bands. Although most of the energy bands of the flares maintain strong correlations (r >= 0.8) with the GLEs, depending only on this evidence we could not precisely imply that GLEs can be caused by solar flares. So, we have attempted to understand possible relativistic energies of the GLEs, which have been determined by availing the relativistic traversing time and velocities of the particles along the nominal path of Archimedean spiral magnetic field lines. Results suggest that the energy released from accelerated particles in high-energy (gamma-ray) solar flares might sometimes cause the GLE. We found that during hard X-ray flares <= 7MeV, the relativistic energy (<= 0.23 GeV) of GLE69 was much less than 1 GeV whereas during SEP flares >30 MeV the possible relativistic energy of GLE69 amounts to similar to 2.78 GeV, and this makes us believe that GLE69 might be caused by the energy released from particle accelerations in high-energy solar flares. On the contrary, during hard X-ray (<= 7 MeV) as well as gamma-ray solar flares (>30 MeV) the relativistic energy of GLE70 amounts to <=similar to 0.35 GeV, indicating that the GLE70 was presumably not caused by the released energy from accelerated particles in the solar flare. Alternatively, the released energy from particle accelerations in solar radio emission type II burst concomitant coronal-mass-ejection-driven shocks seems to have been responsible for causing the GLE70.</P>

      • KCI등재

        Application of dual cloud point extraction for the enrichment of zinc in serum samples of psychiatric patients prior to analysis by FAAS

        Mariam S. Arain,Tasneem G. Kazi,Hassan I. Afridi,Muhammad Bilal,Jamshed Ali,Abdul Haseeb 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.62 No.-

        It is reported in literature that zinc (Zn2+) has antidepressant activity. In present study Zn2+ was analyzed in blood serum of male patients having various psychiatric disorders (schizophrenia, depression, bipolar). As it is usually present in trace levels. Hence a novel, environmental friendly, dual-cloud point extraction (d-CPE) method was developed for the enrichment of its trace levels in acid digested serum samples. In the first step of d-CPE, Zn2+ was complexed with 1-(2-pyridylazo)-2-naphthol (PAN), and the complex was entrapped in a nonionic surfactant (Triton X-114). After achieving cloud point by heating, the mixture was separated into two layers i.e. aqueous and surfactant-rich by centrifugation. In second step of d-CPE, the analyte complex in the surfactant-rich phase was treated wih acid to extract back the metal analytes in acidic aqueous phase, the mixture was again heated upto cloud point and the whole procedure was repeated. This time the aqueous phase, having the metals, was taken and subjected to FAAS using conventional nebulization. The accuracy of the developed methodologies (conventional and d-CPE), were verified by their application to certified reference material of serum (CRM). Reliability of the method was checked by relative standard deviation (%RSD), which was found to be <5%. The limit of detection and limit of quantification were calculated for the proposed method as 1.09 μg/L, and 3.63 respectively and enhancement factor was found to be 40. The developed procedure was successfully applied to the serum samples of patients (male) having different psychiatric disorders and non-psychiatric control subjects for the determination of Zn2+.

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