Free radical scavenging activity of Cirsium japonicum var. maackii flower

Qi Qi Pang,Sanghyun Lee,Ji-Hyun Kim,Eun Ju Cho 충남대학교 농업과학연구소 2023 Korean Journal of Agricultural Science Vol.50 No.1

Obstructive Ileocolitis in Patients With Obstructed Colorectal Cancer – A Matched Case Control Study

Ning-Qi Pang,Tian-Zhi Lim,Yuanpei Zhou,Ker-Kan Tan 대한대장항문학회 2018 Annals of Coloproctolgy Vol.34 No.4

Purpose: Obstructive ileocolitis is an ulcero-inflammatory condition which typically occurs in the ileum or colon proximal to an obstructing colorectal lesion. If left unresolved, it often leads to intestinal perforation. We present a matched case control study of patients with obstructive ileocolitis caused by colorectal cancer to determine if any factors can predict this condition. Methods: This is a retrospective review of 21 patients with obstructive colorectal cancer and histologically proven obstructive ileocolitis from 2005 to 2015 matched for age and sex with 21 controls with obstructing colorectal cancer without obstructive ileocolitis. Results: The 21 patients with obstructive ileocolitis had a median age of 71 years (range, 52–86 years). The most common presenting symptom was abdominal pain (n = 16, 76.2%), followed by vomiting/nausea (n = 14, 66.7%) and abdominal distension (n = 12, 57.1%). Interestingly, the radiological feature of pneumatosis intestinalis was noted in only 1 case. No significant differences were observed in baseline comorbidities, clinical presentations, or tumor characteristics between the 2 groups. Patients with obstructive ileocolitis were found to have a significantly higher total leucocyte count (17.1 ± 9.4×109/L vs. 12.0 ± 6.8×109/L, P = 0.016), lower pCO2 (32.3 ± 8.2 mmHg vs. 34.8 ± 4.9 mmHg, P = 0.013), lower HCO3 (18.8 ± 4.5 mmol/L vs. 23.6 ± 2.7 mmol/L, P < 0.001), lower base excess (-6.53 ± 5.32 mmol/L vs. -0.57 ± 2.99 mmol/L, P < 0.001) and higher serum lactate levels (3.14 ± 2.19 mmol/L vs. 1.19 ± 0.91 mmol/L, P = 0.007) compared to controls. No radiological features were predictive of obstructive ileocolitis. Conclusion: Patients with obstructive ileocolitis tend to present with metabolic acidosis with respiratory compensation, raised lactate, and worse leucocytosis. Radiological features are not useful for predicting this condition.

Learning Probabilistic Kernel from Latent Dirichlet Allocation

( Qi Lv ),( Lin Pang ),( Xiong Li ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.6

Measuring the similarity of given samples is a key problem of recognition, clustering, retrieval and related applications. A number of works, e.g. kernel method and metric learning, have been contributed to this problem. The challenge of similarity learning is to find a similarity robust to intra-class variance and simultaneously selective to inter-class characteristic. We observed that, the similarity measure can be improved if the data distribution and hidden semantic information are exploited in a more sophisticated way. In this paper, we propose a similarity learning approach for retrieval and recognition. The approach, termed as LDA-FEK, derives free energy kernel (FEK) from Latent Dirichlet Allocation (LDA). First, it trains LDA and constructs kernel using the parameters and variables of the trained model. Then, the unknown kernel parameters are learned by a discriminative learning approach. The main contributions of the proposed method are twofold: (1) the method is computationally efficient and scalable since the parameters in kernel are determined in a staged way; (2) the method exploits data distribution and semantic level hidden information by means of LDA. To evaluate the performance of LDA-FEK, we apply it for image retrieval over two data sets and for text categorization on four popular data sets. The results show the competitive performance of our method.

Gallic Acid Ameliorates Cognitive Impairment Caused by Sleep Deprivation through Antioxidant Effect

Pang Xiaogang,Xu Yifan,Xie Shuoxin,Zhang Tianshu,Cong Lin,Qi Yuchen,Liu Lubing,Li Qingjun,Mo Mei,Wang Guimei,Du Xiuwei,Shen Hui,Li Yuanyuan 한국뇌신경과학회 2023 Experimental Neurobiology Vol.32 No.4

Sleep deprivation (SD) has a profound impact on the central nervous system, resulting in an array of mood disorders, including depression and anxiety. Despite this, the dynamic alterations in neuronal activity during sleep deprivation have not been extensively investigated. While some researchers propose that sleep deprivation diminishes neuronal activity, thereby leading to depression. Others argue that short-term sleep deprivation enhances neuronal activity and dendritic spine density, potentially yielding antidepressant effects. In this study, a two-photon microscope was utilized to examine the calcium transients of anterior cingulate cortex (ACC) neurons in awake SD mice in vivo at 24-hour intervals. It was observed that SD reduced the frequency and amplitude of Ca2+ transients while increasing the proportions of inactive neurons. Following the cessation of sleep deprivation, neuronal calcium transients demonstrated a gradual recovery. Moreover, whole-cell patch-clamp recordings revealed a significant decrease in the frequency of spontaneous excitatory post-synaptic current (sEPSC) after SD. The investigation also assessed several oxidative stress parameters, finding that sleep deprivation substantially elevated the level of malondialdehyde (MDA), while simultaneously decreasing the expression of Nuclear Factor erythroid 2-Related Factor 2 (Nrf2) and activities of Superoxide dismutase (SOD) in the ACC. Importantly, the administration of gallic acid (GA) notably mitigated the decline of calcium transients in ACC neurons. GA was also shown to alleviate oxidative stress in the brain and improve cognitive impairment caused by sleep deprivation. These findings indicate that the calcium transients of ACC neurons experience a continuous decline during sleep deprivation, a process that is reversible. GA may serve as a potential candidate agent for the prevention and treatment of cognitive impairment induced by sleep deprivation.

Preparation and Characterization of Anti-GP73 Monoclonal Antibodies and Development of Double-antibody Sandwich ELISA

Li, Qi-Wen,Chen, Hong-Bing,Li, Zhi-Yang,Shen, Peng,Qu, Li-Li,Gong, Lai-Ling,Xu, Hong-Pan,Pang, Lu,Si, Jin Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5

Background: Serum Golgi protein 73 (GP73) as a novel and potential marker for diagnosing hepatocellular carcinoma (HCC) have been found to be elevated in HCC patients and associated with clinical variables representing tumor growth and invasiveness. The aim of this study was to prepare a pair of monoclonal antibodys (mAbs) against GP73 and develop a newly designed double-antibody sandwich enzyme-linked immunosorbent assay (s-ELISA), which would be used in the detection of serum GP73 (sGP73) as well as in the diagnosis of HCC. Materials and Methods: Produced by prokaryotic expression, the purified recombinant GP73 (rGP73), produced by prokaryotic expression, was used to immunize the Balb/c mice. Two hybridoma cell lines against GP73 were obtained by fusing mouse Sp2/0 myeloma cells with spleen cells from the immunized mice. The titers of anti-GP73 mAb reached 1:243,000. Western blotting analysis and Immunohistochemistry staining revealed that anti-GP73 mAb could recognize GP73 protein. The double-antibody s-ELISA was successfully established and validated by 119 HCC and 103 normal serum samples. Results: showed that the detection limit of this method could reach 1.56 ng/ml, and sGP73 levels in HCC group (mean=190.6 ng/ml) were much higher than those of in healthy controls (mean=70.92 ng/ml). Conclusions: Results of our study not only showed that sGP73 levels of HCC patients were significantly higher than those of healthy controls, but also indicated that the laboratory homemade anti-GP73 mAbs could be the optimal tool used in evaluating sGP73 levels, which would provide a solid foundation for subsequent clinical applications.

Preliminary Application of High-Definition CT Gemstone Spectral Imaging in Hand and Foot Tendons

Kai Deng,Cheng-Qi Zhang,Wei Li,Jun-Jun Wang,Xin-Yi Wang,Tao Pang,Guang-Li Wang,Cheng Liu 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.6

Objective: To assess the feasibility of visualizing hand and foot tendon anatomy and disorders by Gemstone Spectral Imaging (GSI) high-definition CT (HDCT). Materials and Methods: Thirty-five patients who suffered from hand or foot pain were scanned with GSI mode HDCT and MRI. Spectrum analysis was used to select the monochromatic images that provide the optimal contrast-to-noise ratio (CNR) for tendons. The image quality at the best selected monochromatic level and the conventional polychromatic images were compared. Tendon anatomy and disease were also analyzed at GSI and MRI. Results: The monochromatic images at about 65 keV (mean 65.09 ± 2.98) provided the optimal CNR for hand and foot tendons. The image quality at the optimal selected monochromatic level was superior to conventional polychromatic images (p = 0.005, p < 0.05). GSI was useful in visualizing hand and foot tendon anatomy and disorders. There were no statistical differences between GSI and MRI with regard to tendon thickening (χ2 = 0, p > 0.05), compression (χ2 = 0.5, p > 0.05), absence (χ2 = 0, p > 0.05) and rupture (χ2 = 0, p > 0.05). GSI was significantly less sensitive than MRI in displaying tendon adhesion (χ2 = 4.17, p < 0.05), degeneration (χ2 = 4.17, p < 0.05), and tendinous sheath disease (χ2 = 10.08, p < 0.05). Conclusion: GSI with monochromatic images at 65 keV displays clearly the most hand and foot tendon anatomy and disorders with image quality improved, as compared with conventional polychromatic images. It may be used solely or combined with MRI in clinical work, depending on individual patient disease condition. Objective: To assess the feasibility of visualizing hand and foot tendon anatomy and disorders by Gemstone Spectral Imaging (GSI) high-definition CT (HDCT). Materials and Methods: Thirty-five patients who suffered from hand or foot pain were scanned with GSI mode HDCT and MRI. Spectrum analysis was used to select the monochromatic images that provide the optimal contrast-to-noise ratio (CNR) for tendons. The image quality at the best selected monochromatic level and the conventional polychromatic images were compared. Tendon anatomy and disease were also analyzed at GSI and MRI. Results: The monochromatic images at about 65 keV (mean 65.09 ± 2.98) provided the optimal CNR for hand and foot tendons. The image quality at the optimal selected monochromatic level was superior to conventional polychromatic images (p = 0.005, p < 0.05). GSI was useful in visualizing hand and foot tendon anatomy and disorders. There were no statistical differences between GSI and MRI with regard to tendon thickening (χ2 = 0, p > 0.05), compression (χ2 = 0.5, p > 0.05), absence (χ2 = 0, p > 0.05) and rupture (χ2 = 0, p > 0.05). GSI was significantly less sensitive than MRI in displaying tendon adhesion (χ2 = 4.17, p < 0.05), degeneration (χ2 = 4.17, p < 0.05), and tendinous sheath disease (χ2 = 10.08, p < 0.05). Conclusion: GSI with monochromatic images at 65 keV displays clearly the most hand and foot tendon anatomy and disorders with image quality improved, as compared with conventional polychromatic images. It may be used solely or combined with MRI in clinical work, depending on individual patient disease condition.

A SINGLE-CHIP-COMPUTER-BASED SEISMIC RECORDER

Kun, Liu Gua,Bing, Pang,Qi, Jiang Fa,Hong, Xia 대한전자공학회 1992 HICEC:Harbin International Conference on Electroni Vol.1 No.1

A cost-effective seismic recorder used to record the maximum acceleration and maximum velocity of earthquake strong-motion sequences together with the time of origin is developed. Taking advantages of the single-chip-computer-based design, it provides not only more information storage but also a low-power-comsumption capability and an easy method of data-collecting afterwards.

Synthesis and luminescent properties of Zn0.890Nb2O6:Eu3+0.05, Bi3+0.005, M+0.055(M = Li, Na, K) phosphors

Fuwang Moa,Liya Zhou,Qi Pang,Yuwei Lan,Zhijuan Liang,유재수 한국물리학회 2013 Current Applied Physics Vol.13 No.2

Zn1exNb2O6:Eu3+ x , Zn0.95-yNb2O6:Eu3+ 0:05, Bi3+ y , and Zn0.890Nb2O6:Eu3+ 0:05, Bi3þ 0:005, M+ 0:055 (M ¼ Li, Na, K) redemitting phosphors were synthesized via solegel method. X-ray power diffraction, scanning electron microscopy, photoluminescence excitation, and emission spectra (PL) were used to characterize the phosphors. The obtained Zn1-xNb2O6:Eu3+ x phosphor showed a stronger excitation band near 400 nm. When Eu3+ and Bi3+ were incorporated into the ZnNb2O6 lattice, a broad band from 300 nm to 350 nm with the center at 329 nm appeared. Taking the ion size difference of Liþ (59 pm), Naþ (99 pm), Kv (137 pm), Eu3+ (95 pm), and Zn2+ (60 pm), the emitting intensity of the phosphor increased observably by adding Liþ and Naþ as charge compensators. The PL intensity of the Kþ-doped in Zn0.945Nb2O6:Eu3+ 0:05, Bi3+ 0:005 was slightly less than those of Zn0.945Nb2O6:Eu3þ 0:05, Bi3 þ 0:005. The chromaticity coordinates of Zn0.890Nb2O6:Eu3+ 0:05, Bi3+ 0:005, Li+ 0:055 (x ¼ 0.67, y ¼ 0.34) were close to the standard of National Television Standard Committee values (x ¼ 0.670, y ¼ 0.330). The fabricated light-emitting diode (LED) further confirmed that the Zn0.890Nb2O6:Eu3+ 0:05, Bi3+ 0:005, Liþ 0:055 phosphors can efficiently absorb up to 400 nm irradiation and emit red light, and are potential candidates as red-emitting components for white LED.

A SINGLE-CHIP-COMPUTER-BASED SEISMIC RECORDER

Liu Gua Kun,Pang Bing,Jiang Fa Qi,Xia Hong 대한전자공학회 1992 대한전자공학회 Conference Vol.1992 No.2

Paint Removal of Airplane & Water Jet Application

Xue, Sheng-Xiong,Chen, Zheng-Wen,Ren, Qi-Le,Su, Ji-Xin,Han, Cai-Hong,Pang, lei Korean Society for Fluid machinery 2014 International journal of fluid machinery and syste Vol.7 No.3

The paint removal and recoating are the very important process in airplane maintenance. The traditional technology is to use the chemical way corroding the paint with paint remover. For changing the defects, corrosion & pollution & manual working, of the traditional technology, the physical process which removes the paint of airplane with 250MPa/250kW ultra-high pressure rotary water jetting though the surface cleaner installed on the six axes robot is studied. The paint layer of airplane is very thin and close. The contradiction of water jetting paint removal is to remove the paint layer wholly and not damage the surface of airplane. In order to solve the contradiction, the best working condition must be reached through tests. The paint removal efficiency with ultra-high pressure and move speed of not damaged to the surface. The move speed of this test is about 2m/min, and the paint removal efficiency is about $30{\sim}40m^2/h$, and the paint removal active area is 85-90%. No-repeat and no-omit are the base requests of the robot program. The physical paint removal technology will be applied in airplane maintenance, and will face the safety detection of application permission.