생리적 및 염증성 유치 치근 흡수면의 미세구조

박윤희,손흥규,최병재 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.4

유치 치근 흡수가 일어나는 경우는 임상에서 많이 접할 수 있다. 유치 치근 흡수는 나이에 따른 생리적 흡수와 치아우식증 및 외상 등으로 비정상적으로 흡수되는 염증성 흡수로 나눌 수 있다. 염증성 흡수는 그 시기와 양상이 생리적인 치근 흡수와는 다르며, 흡수기전이나 흡수면의 미세구조에 있어서도 많은 차이가 있을 것으로 사료된다. 유치 치근 흡수면의 미세구조에 대한 연구는 많이 있었으나, 생리적 흡수면과 염증성 흡수면의 미세구조를 비교한 연구는 드물다. 본 연구는 생리적 흡수면과 염증성 흡수면의 형태 및 인접한 세포를 연구하기 위하여 생리적 및 염증성 흡수로 인해 발거된 유치 치근의 흡수 표면을 주사전자현미경상으로, 조직학적 형태를 광학현미경상으로 관찰하여 다음과 같은 차이점을 알 수 있었다. 1.주사전자현미경상에서 생리적 유치 치근 흡수 표면은 타원형, 원형 및 다각형 모양의 흡수소와가 관찰되었고, 염증성 흡수 표면은 크기가 작으며 형태가 다양하고 매우 불규칙한 무정형 형태의 흡수소와가 관찰되었다. 2.광학현미경상에서 생리적 유치 치근 흡수면은 흡수소와로 구성된 규칙적인 큰 흡수와가 관찰되었고, 염증성 흡수면은 불규칙한 흡수소와가 관찰되었다. 3.광학현미경상에서 생리적 유치 치근 흡수면에는 다핵거대세포가 흡수소와에 직접 접하고 있었으며, 염증성 흡수면은 간엽세포 및 염증세포가 많이 관찰되었다. 4.광학현미경상에서 염증성 치근 흡수면에서는 상아질 흡수를 보상하는 부분적인 백악질 형성이 관찰되었다. Deciduous teeth can be extracted for two reasons, one due to the physiologic resorption and the other by the inflammation at the apex after traumatic injury. Physiologic resorption may be different from pathologic resorption in timing and mechanism. Therefore we resumed the different features of physiologic and pathologic resorption root surfaces. Many previous studies showed micromorphology of resorbed surface of roots of deciduous teeth. But, few studies compared physiological and pathological root resorption surfaces. In this study, we carefully observed microscopic morphologies of those two different root surfaces by scanning electron microscope and histologic features by light microscope. The resultant differences between physiologic and pathologic resorption surfaces of deciduous teeth were as follows: 1. The morphology of pathologic resorption lacunae due to inflammation varied in size and shape with irregular boundaries compared with the physiologic areas from scanning electron microscope observations. 2. From light microscope observations, several large resorption fossae containing numerous resorption lacunae were found, whereas the resorption lacunae were irregular in shape with pathologic resorption surface. 3. Numerous multinucleated giant cells were closely attached to the physiologic resorption lacunae, whereas several kinds of mesenchymal cells with numerous inflammatory cells were found in the areas adjacent to the pathologic resorption surface. 4. Light microscope findings showed that compensating cementum formation took place along some of the areas of inflammatory dentinal resorption. In conclusion, several morphological differences were between physiologic and pathologic root resorption surfaces of human deciduous teeth. The future studies should include cytochemisty to clarify the cellular roles in resorption process observations of pulpal surfaces of coronal and radicular dentin to find the changes that occur in each phase of human deciduous tooth resorption.

부적절하게 수복된 stainless steel crown에 의해 야기된 하악 제1대구치 이소맹출 치험례

박주석,손흥규,최병재 大韓小兒齒科學會 2000 大韓小兒齒科學會誌 Vol.27 No.1

이소맹출이란 영구치열의 발육 과정 중에 국소적 맹출장애로 인하여 정상적 위치에서 벗어난 치아의 맹출을 말한다. 일반적으로 이소맹출은 2∼6% 정도의 이환율을 보이고, 제1대구치에서 호발하며 주로 상악에서 많이 나타나고 하악에서는 드물다. 이소맹출의 원인은 국소적 원인으로 부적절한 치열궁 길이. 상악 후방부의 성장 부족, 제1대구치의 근심 맹출, 비정상적으로 큰 제1대구치 등이 있고, 유전적인 원인으로 나타날 수도 있으며, 부적절하게 형성된 stainless steel crown에 의해서도 유발될 수 있다. 이소맹출된 치아 중 66%는 가역성이므로 3∼6개월 정도의 관찰 기간이 요구된다고 하였으며, 비가역성 이소맹출인 경우에는 brass wire 나 elastic separator를 이용한 비교적 간단한 치료 방법, 제2유구치의 distal discing, Humphrey appliance 등과 같이 제2유규치를 유지하면서 치료하는 방법 및 제2유구치 발거 후 가철식 장치나 cervical traction headgear를 이용하는 방법 등이 소개되고 있다. 본 증례는 연세대하교 치과대학병원 소아치과에 내원한 7세된 남환아로 구강 검사 및 방사선 검사 결과, 4년전 개인 치과의원에서 수복된 우측 하악 제2유구의 stainless steel crown을 제거하고, Humphrey appliance를 제작하여 장착하였으며, 약 10주 후에 고착 상태가 해소되었다. 본 증례에서와 같이 이소맹출은 부적절하게 형성된 stainless steel crown에 의해 일어날 수 있으므로, stainless steel crown의 수복 치료에 있어서, 적절한 크기의 선택, trimming 및 contouring 등이 매우 중요하다. Ectopic eruption is out of a normal position by local eruption disturbance in the developing permanent molar. The prevalence of ectopic eruption is reported to be the between 2 and 6%, most often associated maxillary first permanent molar, whereas, the occurrence for the mandibular is quite rare. The etiologic factors of ectopic eruption are inadequate arch length, lack of growth in the posterior region of the jaw, mesially inclined eruption path of first permanent molars, abnormally large first permanent molars, hereditary factor and a stainless steel crown which has been improperly restored. Ectopic eruption can be treated by the use of brass wire, separating elastics, distal disking and Humphrey appliance and the use of removable appliance and cervical traction headgear after extraction of the second primary molar. This case was that lower right first permanent molar was mesially tilted state by locking on the stainless steel crown of a lower right second primary molar. The stainless steel crown was removed and Humphrey appliance was set. Like this case, ectopic eruption could be happened by the stainless steel crown which improperly restored. In restoration of the stainless steel crown, selection of proper size, trimming and contouring are very important.

제동장치 스퀼소음의 특성 분석을 위한 시험평가시스템 개발

박호,김동규,김흥섭 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.6

Analysis of squeal noise generated during brake operation is an important task for the improvement of brake noise problem. By the use of measuring instrument and techniques, test and evaluation process are to be developed systematically in quantitative analysis. The cost for test and evaluation can be reduced, and the technical power can be raised by the developed system.

榮山湖 上流支流의 水質에 관한 硏究 : 黃龍江에 대하여 On the Hwang Ryong river

朱興珪,朴勝吉 조선대학교 약학연구소 1994 藥學硏究誌 Vol.16 No.1

Physico-chemical and microbiological research of water quality of Hwang ryong river, one of the tributary streams of the upper stream from Lake Youngsan, was performed twice in May 1991, and June 1991, and results are obtained from this research as the following: 1. The pH of the whole research area is 7.0 to 7.4, on much difference from those of common rivers in Korea, which says that there is no special factors to change the pH around Hwang ryong river noticeably. 2. The DO is a little bit lower at the second observation than at the first observation, but it is considered that it is due to the difference of water temperature. Distribution of the DO throughout all research sites is in similar pattern at both observations, the first and the second one. 3. The BOD is 2,21ppm to 3.80ppm that makes comparatively stable quality of river water except from Site 1 to Site 3 where urban life sewage flows in from Songjung-dong and branch streams of Geukrak river join mixed with urban life sewage from Kwangiu City. 4. Some N_2 compounds, nutritive salts, observed are 0.04ppm to 0.09ppm of NH_3-N, 0.06ppm to 0.40ppm of NO_2-N, and 1.30ppm to 4.50ppm of NO_3-N, except from Site 1 to Site 3. There is no water layer polluted by special point source contamination. But 0.08ppm of 1.40ppm NH_3-N, 0.35ppm to 0.73ppm of NO_2-N, and 2.60ppm to 5.20ppm of NO_3-N, are abserved from Site 1 to Site 3, higher than other areas due to the same cause as in case of BOD. Here PO_4-P, is observed almost homogenously to be 0.01ppm to 0.03ppm. This says that nutritive aslts in Hwangryon river are not increased by cause of special point source contamination, but by pollutants dissolved from chemical fertilizers used on farm land. 5. Each of CI-ion and hardness are 21.02ppm to 68.38ppm, and 60.00ppm to 75.50ppm, respectively, a little different from site to site of research, but it is considered that this is not due to point source contamination, compared to other rivers of Korea, but mainly due to soil quality or Clark Number. 6. Normal bacteria and E. Coli are rather low compared to other rivers of Korea. However, the fact that 1.6×10^4 to 1.8×10^4 of E. Coli is analyzed at this research is enough to demand our attention to the management of water quality of Hwangryong river even on the viewpoint of water conservation of the main stream from Lake Youngsan, considering that the water area around this river is the closet to the main stream from Lake Youngsan and also where urban life sewage flows in from Kwangju City including Songjung-dong.

Caliper 조립 Line의 자동화에 관한 연구

장성규,전언찬,박흥식 동아대학교 공과대학 부설 한국자원개발연구소 1995 硏究報告 Vol.19 No.2

In order to improve productivity, we have developed dedicated multi-product and wide variety of products lines suitable for respective automobile models. However, because of a sagging market, in recent years, the productivity of dedicated manufacturing lines has declined remarkably. We have developed a high speed and high-effciency flexible manufacturing line to maintain high productivity in spite of production volume fluctuations and frequent engineering changes. This development has been applied to an assembly line of the caliper.

자동차 차체조립공정설계를 위한 시뮬레이션

황흥석,박태원,조규성,유진식 한국경영과학회 2000 한국경영과학회 학술대회논문집 Vol.- No.1

본 연구에서는 자동차의 차체조립공정설계를 위하여 FACTOR/AIM 및 자체 개발한 생산시스템 성능평가를 위한 시뮬레이션 프로그램을 이용하여 비교 연구하였다. 이를 위하여 먼저 자체에서 개발한 시스템성능 산정 방법으로 초기 해를 구하고 세부 생산라인의 고장 Data와 조립라인의 구성, 운반장비 등의 의 다양한 여건을 고려하기 위하여 FACTOR/AIM을 사용하였다. Data의 분석을 위하여 ExpertFit를 사용하였으며 초기 시스템 모델링 및 Data로 부터 목표 생산시스템을 만족하는 시스템을 단계별로 찾아가는 과정을 사용하여 최적 해를 구하였다. 본 연구에서 분석한 K회사의 경우 목표 생산량 70대/시간을 만족하기 위하여 4 차의 개선을 통하여 71.57대/시간의 생산라인을 구하였다. 본 연구에서 생산조립라인의 공정설계를 위한 시뮬레이션 과정을 실 예를 들어 제시하였으며 다른 제품의 생산공정분서에도 활용 가능하리라 생각된다.

육군 범법자들에 대한 정신의학적 특성 분석

이규환,박흥수,이정태 大韓神經精神醫學會 1989 신경정신의학 Vol.28 No.2

The authors compared two hundred forty-eight imprisoned soldiers with two hundred seventy-nine normal controls using MMPl and Ego-Strength Scale in R.0.K. Army. The results were as follows ; 1) Mean age of imprisoned soldiers was 23.4, while that of controls was 23.9. 2) Educational level of imprisoned soldiers was lower than that of normal controls. 3) Pre-enlistment occupations in imprisoned soldiers chiefly were employees and factory workers (39.9%), while students consisted of 54.4% in normal controls. 4) More than half(61.4%) of the criminal acts had occured during the first year of the military service 5) Of the various criminal acts, absence without leave was the most frequent criminal activities(50.6%). 6) The result of MMPI was significantly different between two groups except L subscale. More specifically, F, Ma, Sc, Pd, Pa subscales which indicate a tendency of behavioral acting out were high in imprisoned soldiers, but all subscales showed below scores of 65. 7) Scores of Ego-Strength Scale in imprisoned soldiers were lower than that of the controls.

Na+/H+ exchanger와 HCO-₃Transporter에 의한 흰쥐 타액선 선세포내 pH 조절

서정택,박동범,손흥규,이종갑 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.2

Intracellular pH (pHi) plays an important role in the regulation of cellular processes by influencing the activity of various enzymes in cells. Therefore, almost every type of mammalian cell possesses an ability to regulate its pHi. One of the most prominent mechanisms in the regulation of pHi is Na+/H+ exchanger. This exchanger has been known to be activated when cells are stimulated by the binding of agonist to the muscarinic receptors. Therefore, the aims of this study were to compare the rates of H+ extrusion through Na+/H+ exchanger before and during muscarinic stimulation and to investigate the possible existence of HCO-₃ transporter which is responsible for the continuous supply of HCO-₃ ion to saliva. Acinar cells were isolated from the rat mandibular salivary glands and loaded with pH-sensitive fluoroprobe, 2', 7' -bis(2-carboxyethyl)-5(6)-carboxyfluorescein(BCECF), for 30min at room temperature. Cells were attached onto the coverglass in the perfusion chamber and the changes in pHi were measured on the iverted microscope using spectrofluormeter. 1. By switching the perfusate from HCO-₃-free to HCO-₃-buffered solution, pHi decreased by 0.39±0.02 pH units followed by a slow increase at an initial rate of 0.04±0.007 pH units/min. the rate of pHi increase was reduced to 0.01±0.002 pH units/min by the simultaneous addition of 1 mM amilorede and 100μM DIDS. 2. An addition and removal of NH+₄ caused a decrease in pHi which was followed by an increase in pHi. The increase of pHi was almost completely blocked by 1mM amiloride in HCO-₃-free perfusate which implied that the pHi increase was entired dependent on the activation of Na+/H+ exchanger in HCO-₃=free condition. 3. An addition of 10μM carbachol increased the initial rate of pHi recovery from 0.16±0.01 pH units/min to 0.28±0.03pH units/min. 4. The initial rate of pHi decrease induced by 1mM amilorede was also increased by the exposure of the acinar cells 10μM carbachol(0.06±0.008pH unit/min) compared with that obtained before carbachol sitmulation (0.03±0.004pH unit/min). 5. The intracellular buffering capacity β1 was 14.31±1.82 at pHi 7.2-7.4 and β1 increased as pHi decreased. 6. The rate of H+ extrusion through Na+/H+ exchanger was greatly enhanced by the stimulation of the cells with 10μM carbachol and there was an alkaline shift in the activity of the exchanger. 7. An intrusion mechanism of HCO-₃ was identified in rat mandibular salivary acinar cells. Taken all together, I observed 3-ford increased in Na+/H+ exchanger by the stimulation of the acinar cells with 10μM carbachol at pH 7.25. In addition, I have found an additional mechanism for the regulation of pHi which transported HCO-₃ into the cells.

거대요관과 거대방광이 동반된 선천성 신성요붕증 1예

이은정,이규백,서정열,김향,박흥재,김영학,권칠훈,이영래 대한신장학회 2001 대한신장학회잡지 Vol.20 No.4

CORBA 클라이언트/서버 구조의 자바 통합 개발 환경의 설계 및 구현

김완수,김흥준,박순규 진주산업대학교 2000 산업과학기술연구소보 Vol.- No.7

Today, most of the well-known software development tools and methods faced with problems of scalability, modularity, granularity, and maintenance. These problems result in the fact that these tools and methods are standalone. In this paper, we propose a design and implementation of software development environment for Java application based upon CORBA-based Client/Server model. Proposed model has facilities to overcome a problem caused by updates and its distribution and is possible to overcome problems of scalability, modularity and granularity because it based upon Client/Server model.