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Park, Chan-Je,Jeon, Kyung-A,Kwon, Ho-Beom 大韓齒科保存學會 2006 Restorative Dentistry & Endodontics Vol.31 No.3
본 연구의 목적은 근관내 약제로 사용되는 수산화칼슘의 제거방법이 근관충전 후 치근단 미세누출에 미치는 영향을 알아보기 위함이다. 70개의 발거된 단근치를 엔진구동형 ProFile로 근관형성한 후 수용성 수산화칼슘 제제를 1주일간 적용하고 두 군으로 나누어 각기 다른 방법으로 제거하였다. A군은 NaOCI로 근관세정만을 시행하였으며, B군은 근관형성 시 사용된 file보다 한 단계 큰 크기의 ProFile을 사용하여 근관을 재형성한 후 NaOCI로 세척하였다. 근관충전 후 전기화학적 방법으로 24일 동안 치근단 누출을 측정, 비교하였다. 본 연구의 결과 수산화 칼슘 제거를 위한 두가지 방법은 근관충전후 치근단 미세누출에 있어서 차이가 없음을 알 수 있었다. This study evaluated the effect of two different calcium hydroxide (Ca(OH)_(2)) paste removal techniques on the apical leakage of canals obturated with gutta percha cones and sealer after removing a Ca(OH)_(2) dressing using an electrochemical method. Seventy extracted single-rooted teeth were instrumented on with Profile rotary files under NaOCI irrigation. Fifty-eight canals were filled with calcium hydroxide paste, which was then removed using one of the following two techniques. In group A, calcium hydroxide was removed using only NaOCI irrigation, and in group B, the canals were re-prepared with a Profile rotary files-one size larger than the previous instrument and were irrigated with NaOCI. In both groups, the root surfaces were coated twice with nail varnish from CEJ to an area 4㎜ away from the apex after canal obturation. Apical leakage was measured using an electrochemical method for 24 days. All the specimens showed leakddffqage that increased markedly in the first three days. There was no significant difference between the two groups (p > 0.05). The effect of two calcium hydroxide paste removal techniques on the apical leakage was not different during a short period.
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이찬주,박범석 동국대학교 교육연구원 2005 교육문제연구 Vol.16 No.-
기호학적 입장에서의 의미 전달은 기호에 의한 의미의 교환이라 할 수 있다. 기호가 언어보다 폭넓은 인간 의식의 이해를 반영한다는 점에서, 인위적으로 설정된 상징체계 이외에 자연스러운 상황이나 이미지 자체도 하나의 기호적 의미의 범주로 해석될 수 있다. 교사와 학생의 가르치고 배우는 활동 역시 지식의 일방적인 전수가 아니라, 다양한 기호들이 상호소통함으로써 의미전달과 창출을 끊임없이 경험하는 해석적 활동이 된다. 교육활동 그 자체가 일종의 해석적 활동이기 때문에 이들 사이에 어떤 형태의 의미교환이 이루어지는가를 규명하기 위해서는 교수-학습의 기호적 역동관계를 이해하는 일이 선행되어야 한다. 따라서 교사와 학생 사이의 의미전달과 획득의 측면을 인간의 기호적 인식의 특성을 통해 밝히는 것은, 기존의 텍스트의 성격 이해를 중심으로한 해석적 연구에서 한 걸음 더 나아가 의미화 과정에서 일어나는 교육 주체들의 인식과정을 설명하는 하나의 계기가 될 것이다. The purpose of this study is to investigate the meaning of teaching-learning process in the view of Semiology. In Semiology, education is the enlarging process of meaning between teacher and students in the classroom as a field of signs. It is the hermeneutics activities to student which learn from the teacher and the text. It means students don't take the meanings not just direct way but translating way as their own meaning structures. In the same way, we can say that even teachers don't convey the meaning to students. They translate the meanings for students representing their own understanding structures. It can be said that the teaching and learning process is the relationships of hermeneutic cycle. In Semiotic view points, educational texts is not just the tools of information transmission. We can recognize the educational texts is the dynamic products from the meaningful actions between the two educational agents. These kinds of Semiotic views can give the new visions to clarify the educational communication between teachers and students in the classroom.
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초고속 광통신용 Avalanche photodiode의 제작 및 특성에 관한 연구
유지범,박찬용 成均館大學校 科學技術硏究所 1994 論文集 Vol.45 No.2
We review the characteristics of Avalache photodiode(APD) for long haul and high bit- rate optical fiber communication system including basic operating principle, excess noise factor, and bandwidth, and we also summarize recent progress. Separate absorption garding, charge and multiplication APD with charge plate layers instead of guard ring was designed and fabricated using metalorganic chemical vapor deposition and reactive ion etching technique. APD shows 37∼48V of breakdown voltage and very low dark current less than 10 nA at 90% of breakdown voltage. Receiver consisting of APD and Ga As pre - amplifier shows sensitivity of - 33.6dBm in the application of the pseudorandom 2^23-1 non- returen- to- zero(NRZ) patterns at 10^-9 bit error rate(BER).
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오종찬,이범주,장재현,원경준,박경희,김동민,박치영,정춘해 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1
Tsutsugamushi disease is an acute febrile illness caused by Orientie. tsutsugsmushi. It is characterized by fever, myalgia, lymphadenopathy, and rash. And it can be easily diagnosed by characteristic eschar and serologic testing. Nearly all of the patients with tsutsugamushi disease improve with antibiotics such as doxycycline. However, the fatality rate of untreated cases is seven to ten percent. Splenic infarction is not common disease which is caused by occlusion of the main splenic artery or any of its branches. It is mainly caused by emboli that arise from cardiovascular disease, but sometimes by regional thrombosis associated with leukemia, myeloproliferative disorder, sickle cell anemia, pancreatitis, splenic torsion and septicemia. We experienced one case of tsutsugamushi disease with splenic infarction, which was improved after doxycycline treatment finished.
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김종민,박창원,오정자,이보경,서경원,서수경,김규봉,김종원,김광진,김영옥,전범석,박찬웅,이선희 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-
1960년대 이후 파킨슨병의 유발물질 중 한 후보로서 망간이 주목받으면서 많은 역학적, 병러학적 연구가 수행죄브다. 그러나 망간이 파킨슨병을 직접 일으키는지, 혹은 파킨슨병과 관련된 부위의 신경세포를 파괴시쿡 파킨슨증만을 초래하는 것인지가 아직 정립되지 않은 실정이다 본 연구에서는 실험동물모델에서 행등학적 변화 측정 및 병리학적, 샐화학적 연구를 통하여 망간의 과다노출글 따른 파킨슨병 유발 여부를 확인하고자 하였다. Sprague-Datylet· 렛드에 망간을 1, 2, 5, 10 mgAg/day의 응량으로 30일 등안 복강 투여하였을 때 모든 망간투여군에서 운동성 감소가 관찰되었다. 뇌조직의 망간 함량을 ion chromatograph?로 측정한 결과 중뇌 흑질과 기저핵 선조체에서 망간 함량의 뚜렷한 증가 소견이 관찰되었으며, 니슬염색체서 선조체의 신경세포수의 유의성 있는 감소가 관찰되었다. 그러나, 흑질의 TH효소 면역염색, GFAP 면역염색, 흑질과 선조체의 T릿효소 western blot 결과는 대조군과 차이가 없었다. 이상의 결과에서, 망간-파킨슨증 모델에서 파킨슨증어 유발되는 기전은 흑질 도파민성 신경 세포의 신호를 받는 선조체 씬경세포의 사멸에 의한 것으로 생각된다. 결론적으로, 망간 독성에 의한 파킨스증 모델에서는 파킨슨 병과는 달리 흑질 도파민성 신경세포의 세포사는 관여하지 않는 것으로 관찰되었다. Manganese(Mn) intoxication causes a parkinsonian syndrome. It may be difficult to distinguish Mn-induced parkinsonism from idiopathic Parkinson disease(IPD). Neuropathological descriptions on the brains with Mn intoxication showed the perferential damage in the globus pallidus and substantia nigra pars reticularis. Pathological reports on the substantia nigra pars compacta(SNpc), a mafor focus of pathologic changes in IPD, are discordant and controversial. The SNpc involvement is of critical importance for the elucidation of pathogenesis of IPD. Therefore, the neurodegeneration in SNpc was investigated in the experimental model of Mn neurotoxicity. Sprague-Dawley rats were administered with manganese chloride(1, 2, 5, 10 mg/kg/day, i.p.) for 30 days. Treated animals showed low levels of distance-traveled from locomotor activity tests. Ion chromatography revealed that Mn accumulation was significant in SN and basal ganglia in Mn-treated animals. Nissl staining showed neuronal loss of the striatum in all treated animals. The degree of neurodegeneration in SN was determined by immunohistochemical staining of tyrosine hydroxylase(TH). The numbers of TH-positive cells on nigral sections were not different from each groups(P>0.05). The densities of glial fibrillary acidic protein immunoreactivity from SN were similar between groups. TH-westen blotting showed no differences between treated animals and controls. In conclusion, the SNpc remains intact in Mn intoxication, and Mn-induced parkinsonism may be caused by damages of output pathways downstream to the nigrostriatal dopminergic system.
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장성종,김병수,부귀범,김동규,박찬국,김만우,김정용,박상헌 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1
Pancreatic pseudocysts usually develop as a complication of acute pancreatitis or repeated attacks of chronic pancreatitis. Pseudocysts may also develop as a result of traumatic injuries or neoplasms. An uncommon complication is massive hemorrhage inside the pancreatic pseudocyst. The exact mechanism of hemorrhage is unknown. Enzymatic digestion, pressure erosion from the cyst mass or a combination of these processes may play an important role. Gastrointestinal hemorrhage associated with a pancreatic pseudocyst can occur in 10 percent of cases. When hemorrhage occurs because of erosion into a blood vessel involved in the pseudocyst, surgery is indicated since the episodes of hemorrhage are often severe and may even be fatal. When there is colonic involvement, various complications may occur. The most dangerous one is spontaneous rupture into the colon, which requires immediate surgical treatment because of high incidence of fulminating sepsis or massive hemorrhage. We examined a sixty eight-year-old man complaining of hematochezia and dizziness, and reported that it was a case of massive lower gastrointestinal hemorrhage caused by pseudocyst of the pancreas ruptured into the colon associated with chronic pancreatitis. On operative findings, the peripancreatic fatty tissue had severe adhesions to transverse colon and tail portion of pancreas, where the pseudocyst had formed. A distal pancreatectomy, splenectomy and resection of transverse colon were performed. By microscopic examination, hemorrhagic necrosis and inflammatory change were observed in the pancreas specimen. The tail portion of pancreas had a 6×6 cm sized cystic mass and was proven to be a pseudocyst with no epithelial lining.
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김병수,장성종,부귀범,조운택,박찬국,김만우,변주남,김정용,전호종 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.1
Small bowel leiomyoma is a rare tumor which may occur wherever smooth muscle is present. The small bowel is the most common site and it makes up 20~30% of all benign small intestinal neoplasms. A spectrum of symptoms are common ranging from nausea, vomiting, abdominal pain, to massive intestinal bleeding. Bleeding is the most common symptom and is usually gross and recurrent. Occasionally it may be life threatening. But, the most serious problem is both the absence of specific clinical symptoms, and the difficulties shown in radiological diagnostics of the small bowel. If conventional diagnostic methods fail to reveal any positive findings for gastrointestinal bleeding, the diagnosis of intestinal leiomyoma should be suspected and an SMA angiography shoud be performed. The angiographic criteria of small bowel leiomyoma is very characteristic. We present a case of leiomyoma with considerable and prolonged gastrointestinal bleeding, which was diagnosed by angiography. A 61-year old woman was admitted with a history of melena over the last 10 days. An SMA angiography showed a hypervascular mass with a diameter of 3×3cm. A segmental resection was performed under the impression of the gastrointestinal bleeding due to leiomyoma of the small bowel. Microscopic examination of the lesion shows interlacing or whorl bundles of spindle shaped ces and no mitosis.
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MODAL CHARACTERISTIC ANALYSIS OF THE APR1400 NUCLEAR REACTOR INTERNALS FOR SEISMIC ANALYSIS
Park, Jong-Beom,Choi, Youngin,Lee, Sang-Jeong,Park, No-Cheol,Park, Kyoung-Su,Park, Young-Pil,Park, Chan-Il Korean Nuclear Society 2014 Nuclear Engineering and Technology Vol.46 No.5
Reactor internals are sensitive to dynamic loads such as earthquakes and flow induced vibration. Thus, it is essential to identify the dynamic characteristics to evaluate the seismic integrity of the structures. However, a full-sized system is too large to perform modal experiments, making it difficult to extract data on its modal characteristics. In this research, we constructed a finite element model of the APR1400 reactor internals to identify their modal characteristics. The commercial reactor was selected to reflect the actual boundary conditions. Our FE model was constructed based on scale-similarity analysis and fluid-structure interaction investigations using a fabricated scaled-down model.
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