Collagen으로 유발된 생쥐의 관절염에 대한 당귀사역가오수유생강탕(當歸四逆加吳茱萸生薑湯)의 효과

김민균 ( Min Kyun Kim ),오민석 ( Min Seok Oh ) 한방재활의학과학회 2011 한방재활의학과학회지 Vol.21 No.2

Objectives: This study was carried out to know the effects of Danggwisayeokgaohsuyusaenggang-tang(hereinafter referred to DST) on arthritis induced by collagen on DBA/1 OlaHsd mice. Methods: For this purpose, DST was orally administered to mouse with arthritis induced by collagen Ⅱ. Cytotoxicity, high performance liquid chromatograph(HPLC) analysis, arthritis index, value of immunocyte in draining lymph node and paw joint, cytokine were measured in vivo. Results: 1. The cytotoxicity against human fibroblast cells(hFCs) was not measured in any concentration. 2. In HPLC analysis, There are high peak patterns at 8 minute(min), 12 min, 35 min, 45 min. 3. The arthritis index was decreased significantly. 4. The degree of arthritis induced damage of joint of DST group is slight compared with control group in histopathologic observation(Hematoxylin and eosin stain(H&E), Masson`s trichrome(M-T) staining). 5. In total cell counts of draining lymph node(DLN) and paw joint, the cells in DLN decreased significantly on DST 200 mg/kg and the cells in paw joint decreased significantly on 200 mg/kg and 50 mg/kg. 6. In DLN, CD4+/CD25+, CD3+/CD69+, major histocompatibility complex(MHC) class-II/CD11c+ cells decreased significantly on DST 200 mg/kg and 50 mg/kg, CD3+/CD8+ cells decreased significantly on DST 200 mg/kg, CD4+, CD3+/CD44+ cells decreased. 7. In paw joints, CD4+, CD11b+/Gr-1+ cells decreased significantly on DST 200 mg/kg and 50 mg/kg. 8. In joints, levels of IL-1β, IL-6, TNF-α, cyclo-oxygenase-2(COX-2), NOS-II were decreased on DST 200 mg/kg and DST 50 mg/kg. 9. In analysing of cytokine in CD3/CD28 activated spleen, IL-17 was decreased significantly, IL-4 was increased significantly and INF-γ was decreased on DST 200 mg/kg. 10. In analysing of cytokine in collagen activated spleen, IL-17 were decreased significantly, IL-4 was increased significantly. Conclusions :This results demonstrated that DST suppressed the inflammatory progression of collagen-induced arthritis(CIA) mice and supported further studies are required to survey continuously in looking for the effective substance and mechanism in the future.

Determining the Optimal Cooking Time for Cooking Loss, Shear Force, and Off-Odor Reduction of Pork Large Intestines

Sung-Su Kim,Yee Eun Lee,ho Hyun Kim,Joong-Seok Min,Dong Gyun Yim,Cheorun Jo 한국축산식품학회 2022 한국축산식품학회지 Vol.42 No.1

The objective of this study was to determine the optimal cooking time by considering the cooking loss, shear force, and off-odor reduction of pork large intestines. Commercial pork large intestines were purchased, quartered perpendicularly, and cooked in boiling water for 40, 120, 180, and 240 min. Cooking loss of the samples increased after 240 min of cooking (10.92, p<0.05) while shear force value was lower at 240 min (4.45) compared to that at other cooking times (p<0.001). The amount of major volatile organic compounds showed a decreasing trend with increasing cooking time. In particular, the amount of methyl pentanoate (17,528.71) and methyl isobutyrate (812.51), compounds with a relatively low odor threshold, decreased significantly after 120 min of cooking and no change was observed thereafter (p<0.05). In addition, the amount of 2-pentanol (3,785.65) and 1-propanol (622.26), possibly produced by lipid oxidation, significantly decreased at the same cooking time (p<0.001). In the principal component analysis, only the 40 min cooking time was significantly different from other cooking time by high amounts of 1-propanol, 2-pentanol, and methyl isobutyrate. In conclusion, in the present study, the optimal cooking time for pork large intestines was 120 min in terms of off-odor reduction, cooking loss, and shear force.

자바리, Epinephelus bruneus의 난 발생과 부화에 미치는 수온의 영향

양문호,최영웅,정민민,구학동,오봉세,문태석,이창훈,김경민,한석중,Yang, Moon-Ho,Choi, Young-Ung,Jung, Min-Min,Ku, Hag-Dong,Oh, Bong-Sae,Moon, Tae-Seok,Lee, Chang-Hoon,Kim, Kyong-Min,Han, Seock-Jung 한국발생생물학회 2007 발생과 생식 Vol.11 No.2

This study examined temperature effect in egg development and hatching of longtooth grouper, Epinephelus bruneus. Fertilized embryos was not growth after morula stage at $15^{\circ}C$, at 18, 21, 24 and $27^{\circ}C$, the required time from fertilized embryos to hatching were 70 h. 30 min., 44 h. 10 min., 29 h. 10 min. and 24 h. 30 min., respectively. The hatching rates at $24^{\circ}C$ were higher than the other conditions and the hatching was not occurred at $15^{\circ}C$. These results suggest that the water temperature range of egg development and hatching was $18{\sim}27^{\circ}C$. 이 연구는 실내 사육수조에서 자연산란 후 수정된 난을 대상으로 수온에 따른 난 발생속도와 부화율을 조사하였다. 부화에 이르기까지 각 수온조건에서 소요된 시간은 $15^{\circ}C$에서 상실기 이후 발생이 진행되지 않았고, 18, 21, 24, $27^{\circ}C$에서 각각 70시간 30분, 44시간 10분, 29시간 10분 그리고 24시간 30분이 소요되었다. 부화율은 $15^{\circ}C$에서 0%였고, 18, 21, 24 그리고 $27^{\circ}C$에서 각각 $8.3{\pm}1.2%$, $18.0{\pm}6.2%$, $24.0{\pm}4.0%$ 그리고 $17.0{\pm}7.2%$로 뚜렷한 차이 없이 $24^{\circ}C$에서 다소 높았고 21와 $27^{\circ}C$에서 비슷한 경향이었으며 $18^{\circ}C$에서 가장 낮게 나타났다. 이러한 결과에서 자바리의 난발생 수온범위는 $18{\sim}27^{\circ}C$로 제안된다.

Antioxidant Activity and Whitening Effect of Lindera erythrocarpa Extract

Min ?Chul Kang,Ryeo Kyeoung Ko,Ju-Yeop Lee,Haeng-Bum Kim,Bong-Seok Kim,Jong-Heon Han,Seong-Hyun An,Gi-Ok Kim 한국생물공학회 2008 한국생물공학회 학술대회 Vol.2008 No.10

The Theology of Images in the Reformation

Min?Seok Kim 한국기독교학회 2016 한국기독교신학논총 Vol.101 No.-

교회 역사는 건축, 음악, 그림, 캘리그라피, 드라마, 조각, 영화, 스테인드글라스 등과 같은 예술적이고 기술적인 시각 매체 혹은 수단들을 통해서도 복음이 사람들에게 전달되어 왔음을 알려주고 있다. 더 나아가 현대 사회에서는 시각 이미지의 긍정적 가치와 의미가 더욱 대두되고 있다. 그 결과로 현대 교회들은 영상, 그림, 그리고 드라마와 같은 시각 이미지들을 설교와 예배에 대한 보조 도구들로 사용하기도 한다. 이러한 상황은 개신교 전통의 현대교회들을 위해서 개신교 신학 안에서 이미지에 대한 긍정적인 신학의 추구와 발전을 요구하고 있다. 그러나 많은 개신교회와 개신교 목회자들이 개신교 신학에는 시각 이미지에 대한 부정적 관점만 있을 뿐이라고 추정하는 것처럼 보인다. 그리고 이러한 단정적 추론은 개신 교회에서 경건과 예배를 위해 사용되는 시각 이미지에 대해 긍정적인 신학을 추구하고 찾는 데 걸림돌로 작용하고 있다. 이러한 상황 속에서 본 연구는 개신교 신학들 중에서도 이미지에 대한 긍정적 관점이 있는지를 찾고자 한다. 이 목적을 수행하기 위해 본 논문은 먼저 중세 후기의 이미지 오용을 다루고, 그 후에 세명의 종교 개혁자들(안드레아스 보덴슈타인 폰 칼슈타트, 마르틴 루터, 그리고 장 칼뱅)의 관점을 분석한다. 칼슈타트는 종교 개혁 진영에서 맨 처음으로 급진적 성상 파괴 운동을 공식적으로 시작했다. 그리고 루터와 칼뱅은 여전히 개신교 전통의 현대 교회들에 영향력을 행사하고 있다. 필자는 이러한 이유 때문에 16세기의 종교 개혁가들 중에 위에 언급된 세 명의 종교 개혁자를 선택했다. Church history has shown that the Gospel has been communicated and transmitted to people through artistic and technological media or ways such as architecture, music, paintings, calligraphy, drama, sculpture, movies, stained glass, etc. Moreover, in modern society, the visual image is increasing in positive value and meaning so that modern churches have used visual images such as films, pictures, and dramas as aids for preaching or worship. This contemporary circumstance calls for the pursuit and development of the positive theology of the image in Protestantism for our contemporary Protestant churches. However, the majority of Protestant churches and minsters seems to assume that there is only a negative perspective toward visual images in the theology of the Reformation. This assumption presents an obstacle to pursuing and finding a positive theology of images in order to use visual images for devotion and worship in Protestantism. With this context as a foundation, the objective of this study is to find a positive perspective of visual images in Protestant theologies. To this end, this article addresses the abuse of images in the late medieval period and then analyses three reformers’ perspective of image: Andreas Bodenstein von Karlstadt, Martin Luther, and John Calvin. The first was the official initiator of the iconoclasm in the sixteenth–century Reformation and the latter two reformers have still exerted influence on our contemporary Protestant churches. This is the reason why I choose these three among the sixteenth–century reformers.

Min-Hash를 이용한 효율적인 대용량 그래프 클러스터링 기법

이석주(Seok-Joo Lee),민준기(Jun-Ki Min) 한국정보과학회 2016 정보과학회논문지 Vol.43 No.3

그래프 클러스터링은 서로 유사한 특성을 갖는 정점들을 동일한 클러스터로 묶는 기법으로 그래프 데이터를 분석하고 그 특성을 파악하는데 폭넓게 사용된다. 최근 소셜 네트워크 서비스와 월드 와이드 웹, 텔레폰 네트워크 등의 다양한 응용분야에서 크기가 큰 대용량 그래프 데이터가 생성되고 있다. 이에 따라서 대용량 그래프 데이터를 효율적으로 처리하는 클러스터링 기법의 중요성이 증가하고 있다. 본 논문에서는 대용량 그래프 데이터의 클러스터들을 효율적으로 생성하는 클러스터링 알고리즘을 제안한다. 우리의 제안 기법은 그래프 내의 클러스터들 간의 유사도를 Min-Hash를 이용하여 효과적으로 추정하고 계산된 유사도에 따라서 클러스터들을 생성한다. 실세계 데이터를 이용한 실험에서 우리는 본 논문에서 제안하는 기법과 기존 그래프 클러스터링 기법들과 비교하여 제안기법의 효율성을 보였다. Graph clustering is widely used to analyze a graph and identify the properties of a graph by generating clusters consisting of similar vertices. Recently, large graph data is generated in diverse applications such as Social Network Services (SNS), the World Wide Web (WWW), and telephone networks. Therefore, the importance of graph clustering algorithms that process large graph data efficiently becomes increased. In this paper, we propose an effective clustering algorithm which generates clusters for large graph data efficiently. Our proposed algorithm effectively estimates similarities between clusters in graph data using Min-Hash and constructs clusters according to the computed similarities. In our experiment with real-world data sets, we demonstrate the efficiency of our proposed algorithm by comparing with existing algorithms.

Evaluation of High Power Light Emitting Diodes (HPLEDs) as Potential Attractants for Adult Spodoptera exigua (Hubner) (Lepidoptera Noctuidae)

( Min Seok Oh ),( Chi Hoon Lee ),( Sang Guei Lee ),( Hoi Seon Lee ) 한국응용생명화학회 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.3

To evaluate high-power light-emitting diodes (HPLEDs) as potential attractants for Spodoptera exigua adults, attractiveness of specific wavelengths, illuminance intensity, and light-exposure times were investigated and compared to that of fluorescent light. The white light (40 lux treatment) attracted significantly more S. exigua than other attractants. The optimal light-exposure time, based on the highest attraction rate, was 60 min. Evaluation of attraction and repellent rates under optimal conditions showed the white HPLED had the highest attraction rate (91.1%), and the red HPLED had the highest repellence rate (33.3%). Based on relative efficiency values, the white HPLED was about 9.14 times as efficient as the fluorescent light. These data clearly showed that S. exigua showed the greatest attraction to the white HPLED at 40 lux intensity and 60 min light-exposure time.

Evaluation of High Power Light Emitting Diodes (HPLEDs) as Potential Attractants for Adult Spodoptera exigua (Hübner)

Min-Seok Oh,Sang-Guei Lee,Ju-Hyun Jeon,Hoi-Seon Lee 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.10

To response evaluation of high power light emitting diodes (HPLEDs) as potential attractants to the Spodoptera exigua adults, we investigated the attractiveness of specific wavelength, illuminance intensity and light-exposure time, and compared them to the fluorescent. The all light treatments with the 40 lux intensity attracted the significantly highest number of S. exigua. The optimal light-exposure time exhibited the highest attraction rate at the 60 min. When the attraction and repellent rate in the optimal conditions to the S. exigua was surveyed, the white HPLED exhibited the highest attraction rate (91.1%), whereas the red HPLED exhibited the most repellent rate (33.3%). When evatuated of illuminance efficiency with fluorescent as control, white and red HPLED were found to be 9.14 and 10.34 times more efficient than fluorescent. These data clearly show that both the 40 lux intensity and the 60 min light-exposure time by using the white HPLED was the most suitable for attraction of the S. exigua.

청소년들의 최대 골량 향상을 위한 운동 가이드라인

민석기 ( Seok-ki Min ),오태웅 ( Taewoong Oh ),김상현 ( Sang Hyun Kim ),조진경 ( Jinkyung Cho ),정호연 ( Ho-yeon Chung ),박동호 ( Dong-ho Park ),김창선 ( Changsun Kim6 ) 한국운동생리학회(구 한국운동과학회) 2020 운동과학 Vol.29 No.1

PURPOSE: An increase in bone mineral density during adolescence increases resistance to fractures in older age. The Korean Society for Bone and Mineral Research and the Korean Society of Exercise Physiology developed exercise guidelines to increase the peak bone mass (PBM) in adolescents based on evidence through a systematic review of previous research. METHODS: Articles were selected using the systematic method, and the exercise guidelines were established by selecting key questions (KQs) and defining the effects of exercises based on evidence through a literature review for selecting the final exercise method. There were 9 KQs. An online search was conducted on articles published since 2000, and 93 articles were identified. RESULTS: An increase in PBM in adolescence was effective for preventing osteoporosis and fractures in older age. Exercise programs as part of vigorous physical activity (VPA) including resistance and impact exercise at least 5 to 6 months were effective for improving PBM in adolescents. It is recommended that resistance exercise is performed 10 to 12 rep·set^-1 1-2 set·region^-1 and 3 days·week^-1 using the large muscles. For impact exercises such as jumping, it is recommended that the exercise is performed at least 50 jumps·min^-1, 10 min·day^-1, and 2 days·week^-1. CONCLUSIONS: Exercise guidelines were successfully developed, and they recommend at least 5 to 6 months of VPA, which includes both resistance and impact exercises. With the development of exercise guidelines, the incidence of osteoporosis and fractures in the aging society can be reduced in the future, thus contributing to improved public health.

鐵 陽極 溶出反應에 의한 燐成分 除去

강민수,김형석,박승조 동아대학교 환경문제연구소 1995 硏究報告 Vol.18 No.1

This study was on the removal of phosphorus compounds in domestic and synthetic wastewater using iron-anode electrolytic reactor. The experiments were performed at different current, reaction time and flow rate. The results are as follows ; 1. For the synthetic wastewater with the flow rate of 1.5 ℓ/min and 0.75 ℓ /min, the removal efficiencies were 97% and 98%, respectively. The order conditions of this continuous experiments are current density 2.54 A/dm² and reaction time 20 minutes. 2. The optimal conditions of the batch experiment for synthetic wastewater were current density 0.95 A/dm² and reaction time 3.0 minutes with no addition of electrolyte. With electrolyte, the optimal conditions were current density 2.54 A/dm² and reaction time 1.0 minutes. For the both experiments, the removal efficiencies were far over 97%.