ART2 신경회로망을 이용한 공구마모 모니터링

오동백,노민석,장우일,최국진,홍대선 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

Titanium alloys have been mainly used for aircraft components as well as implant materials. Although a number of cutting tools and cutting methods have been developed for improving the cutting processes, they have difficulties such as tool wear and failure. This study considers a novel approach to on-line monitoring of tool wear and failure in titanium alloy cutting processes. The on-line monitoring system mainly consists of two parts: The one is on-line data acquisition with sensors and a DSP board through LabView and a web server, and the other is learning and prediction of tool wear and failure using an ART2 neural network algorithm. The system is installed at an on-site machine tool to monitor high speed steel(HSS) tools for cutting titanium alloy. A number of experiment are carried out to demonstrate the effectiveness of the proposed system.

기도 이물의 임상적 고찰

김영석,이승규,이민재,백병준,오천환 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.2

Aspiration of foreign bodies into the airway is a common problem in spite of efforts to educate the public and it can be sometimes fatal accidents. A retrospective study has been performed for 34 cases of airway foreign bodies, which were obtained from April 1994 to August 1998 at Chunan hospital of Soonchunhyang University. The results were as follows: 1) Among the 34 cases, 26 cases(76.4%) were under the age of 3. The ratio of male and female was 1.4:1. 2) The most common symptom after foreign body aspiration was intractable cough(38.2%). 3) Abnormal findings in the chest X-ray films were found 24 cases(70.6%) and the most common abnormal radiologic feature was combination of pneumonia and atelectasis(37.5%), followed by combination of pneumonia and emphysema(16.6%), pneumonia alone(16.6%). 4) The nature of foreign body was vegetables in 20 cases(58.8%), miscellaneous in 11 cases(32.4%), metals in 2 cases(5.9%) and plastics in 2 cases(5.9%). 5) By distribution of the location of foreign bodies, 26 cases(76.4%) were located in the main bronchus(20 cases in right side and 6 cases in left side), 5 cases were in trachea, 2 cases were in larynx and 1 case was located at carina level. 6) By duration of foreign body lodgement in the airway, 15 cases(44.1%) were found within 24 hours, 9 cases(26.5%) were within 7 days, 7 cases(20.6%) were within 30 days and 3 cases(8.8%) were found over 1 month. 7) In mode of treatment, ventilating bronchoscopic removal under general anesthesia was performed in 29 cases(85.3%), thoracotomy with bronchotomy in 2 cases, thoracotomy with lobectomy in 1 case and postural drainage in 2 cases. 8) Complication rate according to the nature of foreign body was most high in vegetables(68.2%). 9) Correlation between complication rate and the duration of the foreign bodies in situ was definite.

비부비동 반정성 유두종의 전산화 단층촬영상과 자기공명영상의 분석

배창훈,서영중,이석춘,천승민,백운희,정은채,송시연,김용대 영남대학교 의과대학 2005 Yeungnam University Journal of Medicine Vol.22 No.2

Background: Computed tomography (CT) is commonly used to evaluate the degree of sinus involvement in case of inverted papilloma (IP). However, CT cannot differentiate tumor from adjacent inflammatory mucosa or retained secretions. By contrast, magnetic resonance imaging (MRI) has been reported to be useful in distinguishing IP from paranasal sinusitis. This study investigated whether preoperative assessment with MRI and CT accurately predict the extent of IP. Materials and methods: CT and MRI were retrospectively reviewed in 9 case of IP. Patients were categorized into staged based on CT and MRI findings according to the staging system proposed by Krouse. The involvement of IP in each sinus was also assessed. Results: Differentiation of IP from inflammatory disease may be more successful in routine case where the inflammatory mucosa has low signal intensity on T1-weighted images and very high signal intensity on T2-weighted images. CT imaging could not differentiate tumor from adjacent inflammatory mucosa or retained secretions. Conclusion: Preoperative MRI of IP can predict the location and extent of the tumor involvement in the paranasal sinuses and sometimes predicts malignant changes.

Differentiation of Helicobacter Spp. with PCR based RFLP method in the tartar and feces of pet animals

Min-Won Baek,Jong-Hwan Park,Seung-Hyeok Seok,Hui-young Lee,Dong-Jae Kim,Hyung-Min Uhm,Jae-Hak Park 한국실험동물학회 2005 한국실험동물학회 학술발표대회 논문집 Vol.2005 No.-

13-Week Repeated Oral Toxicity Study of Isaria tenuipes in Sprague-Dawley Rats

Min Kwon,Dong-Seok Seo,Jin-Seok Kang,Mi-Hye Jeong,Young-Sup Lee,Tae-Gu Kang,In-Young Baek,Beom-Seok Han 한국농약과학회 2011 한국농약과학회 학술발표대회 논문집 Vol.2011 No.11

Engraving High-Density Nanogaps in Gold Thin Films via Sequential Anodization and Reduction for Surface-Enhanced Raman Spectroscopy Applications

Baek, Kwang Min,Kim, Jaehoon,Kim, Shinho,Cho, Seunghee H.,Jang, Min Seok,Oh, Jihun,Jung, Yeon Sik American Chemical Society 2018 Chemistry of materials Vol.30 No.17

<P>To realize a more rapid and accurate detection technique for diverse trace molecules, surface-enhanced Raman scattering (SERS) analysis has been extensively investigated in recent decades. However, a practical fabrication method to scalably and reproducibly produce SERS substrates with highly effective SERS-active sites and extensive optical tunability still remains an important research target. Here, we present an electrochemical pathway to generate a high-performance SERS substrate. This method provides not only ultrahigh-density hot spots as a form of nanogaps for strong and uniform SERS signal enhancement but also tunable plasmonic properties for capability of matching the plasmonic resonance wavelength with that of the Raman excitation laser. The unique Au nanopillar array decorated with ultrafine Au nanoparticles records a high SERS signal enhancement effect, which enables trace-molecule detection on the entire measured area with highly reproducible signal intensity. Also, via aptamer-functionalization on this substrate, an extremely sensitive and highly selective SERS-based Hg<SUP>2+</SUP> ions detection sensor is demonstrated. Trace-amount (10 ppb) Hg<SUP>2+</SUP> ions can be selectively identified in a mixture solution containing six different metallic ion species as well as in a beverage containing numerous other components.</P> [FIG OMISSION]</BR>

Autologous Cytokine-Induced Killer Cells for Longer Recurrence Free Survival for Hepatocellular Carcinoma as an Adjuvant Therapy: A Case Series

( Min Seong Kim ),( Min Kyung Baek ),( Myung Hee Kim ),( Jae Ho Park ),( Deok Yeong Kim ),( Hyuk Soo Eun ),( Woo Sun Rou ),( Jong Seok Joo ),( Eaum Seok Lee ),( Seok Hyun Kim ),( Byung Seok Lee ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: Autologous cytokine-induced killer cells were used to reduce recurrence in hepatocellular carcinoma as an adjuvant therapy. Our study aimed to evaluate the efficacy of Autologous cytokine-induced killer Cells after curative therapy in primary hepatocellular carcinoma(HCC) in CNUH cases retrospectively. Methods: The study included HCC patients who visited CNUH after surgery, Radiofrequency ablation(RFA), or Transarterial chemoembolization(TACE) from Jan. 2016 to Mar. 2018. The autologous CIK(created by incubation of patient’s peripheral blood mononuclear cells with interleukin 2 and an antibody against CD3) were treated as an adjuvant drug within 2.3 months after curative therapy. Clinical characteristics at baseline and after CIK treatment, and adverse events and recurrence free survival period were collected. Results: Eight of HCC patients were treated with CIK immunotherapy. Patient’s median age was 50 (range 45-67) and 6 of 8 patients were HCC stage II according to the AJCC staging system (7th ed). Before taking immunotherapy, 6 patients received surgery, one patient received RFA and the other received TACE. All patients received average 10 months of CIK as an adjuvant therapy. The median time of recurrence-free survival (RFS) was 10.0 months. 5 patients experienced tumor recurrence or death by the time of the data cut-off date. 4 patients who experienced tumor recurrence underwent additional RFA or TACE and three of these 4 patients were constantly receiving one to eight CIK treatments after additional therapy. There was one death in the study period, which was due to recurrence of liver cancer. Adverse events were reported for 2 and were mild to moderate grade of diarrhea and vomiting. No patient discontinued treatment due to an adverse event. Conclusions: In this CNUH case series using the autologous CIK cells for HCC patients as an adjuvant therapy, the median time of recurrence-free survival (RFS) was 10.0 months. It also offers a new option that can be used as an ongoing therapy even after the first recurrence.

06 식품의약품안전처 SESSION : 국가 잔류농약 안전관리 연구 보고회 ; 식품원재료 섭취량 산출 소프트웨어의 검증 및 식품적용 연구

백민석 ( Min Seok Baek ),고상훈 ( Sang Hoon Ko ),윤요한 ( Yohan Yoon ) 한국환경농학회 2014 한국환경농학회 학술대회집 Vol.2014 No.-

식품에 직.간접적으로 잔류되는 위해물질의 노출량 평가는 식품 위생 및 건강에 있어 매우 중요하다. 식품 내 위해물질의 노출량 평가를 위해서는 객관적이고 합리적인 식품원재료(food commodity) 섭취량 정보를 획득하는 것이 필수적인데, 식품 중에는 여러 가지의 식품원재료들이 혼합된 상태로 존재하기 때문에 식품 섭취량을 산출하기 쉽지 않다. 우리나라에서는 매년 국민건강영양조사(KNHANES)를 통해 국민들의 일일 식품 섭취량을 조사하여 개개의 식품 섭취량 자료를 제공한다. 하지만 국민건강영양조사의 식품 섭취량 자료는 가공식품 및 혼합식품을 통한 식품원재료 섭취량을 고려하지 않는 문제점이 있다. 따라서 지난 연구에서는 자체적으로 구축한 식품원재료 환산 알고리즘을 이용하여 식품원재료 섭취량 산출 소프트웨어를 개발하였다. 국민건강영양조사의 식품 섭취량 데이터베이스와 자체적으로 구축한 레시피 데이터베이스가 식품원재료 섭취량산출 소프트웨어에서 1일 식품 섭취량 데이터를 얻기 위하여 사용되었다. 식품원재료 환산 알고리즘을 이용하여 개발된 소프트웨어는 표준 배합비를 이용하여 모든 원재료의 배합비를 탐색하여 오직 식품원재료로만 표시되고 그 섭취량을 산출할 수 있다. 본 연구에서는 식품원재료 섭취량 산출 소프트웨어의 성능을 검증하기 위해 실제 식품 섭취량 데이터에 적용해 보고자 하였다. 이를 위해,국민건강영양조사 제4기 2차년도(2008년)부터 제5기 1차, 2차, 3차년도(2009, 2010, 2011, 2012년)식품섭취조사 자료를 수집하였고 이를 이용하여 검증 시뮬레이션을 수행하였다. 시뮬레이션 결과,국민건강영양조사 자료의 원재료 식품섭취량과 식품원재료 섭취량 산출 소프트웨어의 산출값이 유의한 차이가 없음을 확인할 수 있었다. 또한 식품원재료 섭취량 산출 소프트웨어는 본 연구를 통하여 개발된 알고리즘을 통합적으로 구현할 수 있도록 고안되었으며 이를 이용하여 방대한 양의 섭취량 자료를 빠르고 편리하게 처리하여 식품별 원재료의 섭취량을 산출할 수 있다. 본 연구로 개발된 소프트웨어를 활용하면 농산물, 축산물, 수산물 및 이들의 가공품으로부터 섭취되는 원료식품 섭취량을 객관적, 합리적으로 계산할 수 있다. 소프트웨어를 통하여 계산된 객관적인 원료식품 섭취량 정보는 농축수산물 및 가공식품을 통해 섭취된 잔류농약을 비롯한 화학 잔류물질의 위해성 평가를 위한 좋은 기초 자료가 될 것이다.

Strength analysis of the driving shift gears for a 67 ㎾ class agricultural tractor according to tire type

Seung Min Baek,Wan Soo Kim,Yeon Soo Kim,Seung Yun Baek,Nam Gyu Lee,Seok Pyo Moon,Hyeon Ho Jeon,Young Soo Choi,Taek Jin Kim,Yong Joo Kim 충남대학교 농업과학연구소 2020 Korean Journal of Agricultural Science Vol.47 No.4

세라믹 모노리스 담체의 열충격 특성에 관한 연구

백석흠(Seok-Heum Baek),박재성(Jae-Sung Park),김민건(Min-Gun Kim),조석수(Seok-Swoo Cho) 대한기계학회 2010 大韓機械學會論文集A Vol.34 No.2

공업용 세라믹은 자체의 특이한 물리적 특성으로 인하여 극한의 열 및 화학적 환경에서도 적용할 수 있는 우수한 고온 재료이다. 세라믹은 고온에서 저온으로 빠르게 이동되면 열충격을 받는다. 본 연구에서는 열충격에 대한 매개변수로 임계온도차이를 제안한다. 세라믹 부품에 대한 임계온도차이는 부품 크기와 대류열전달계수등에 의해 영향을 받는다. 부품의 열충격 특성은 비정상 열응력에 의해 평가된다. 비정상 열응력이 파단계수를 초과한다면 열충격 균열이 표면에서 시작된다고 가정할 수 있다. 물에 대한 임계온도차이는 공기에 대한 임계온도차이보다 적다. 본 연구에서 사용된 국내 승용차용 삼원 촉매 담체는 반경 및 축방향 온도차이가 임계온도차이 아래에 존재하므로 충분한 열충격 성능을 가지고 있었다. Technical ceramics, due to their unique physical properties, are excellent candidate materials for engineering applications involving extreme thermal and chemical environments. When ceramics are rapidly cooled, they receive thermal shock. The thermal shock parameter is defined as the critical temperature difference. The critical temperature difference for ceramic parts is influenced by its size, the convective heat transfer coefficient, etc. The thermal shock for a component is analyzed by using the transient thermal stress. If the transient thermal stress exceeds the modulus of rupture (MOR), cracking by thermal shock is initiated. The critical temperature difference for water is less than the critical temperature difference for air. The three-way catalyst substrate used in this study has an adequate performance against thermal shock because its radial and axial temperature differences existed below the critical temperature differences.