성대마비환자를 대상으로 시행한 후두근전도검사의 임상적 유용성

최홍식,최영준,문상우,김태만,최홍식,최영준,문상우,김태만 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.2

그레이브스병에서 치료에 따른 폐동맥압의 변화

남택만,조한수,이진서,송영림,김두만,두영철,박철영,정인경,홍은경,이성진,오기원,김현규,유재명,최문기,유형준,박성우 대한내분비학회 2003 Endocrinology and metabolism Vol.18 No.5

연구배경: 갑상선기능항진증에 의한 갑상선중독증 환자들은 호흡곤란을 호소하며, 그 원인으로 호흡근의 근력 약화, 좌심실부전으로 인한 폐모세혈관의 울혈, 기도저항의 증가, 갑상선종으로 인한 기관의 압박, 호흡기능 이상 등이 거론되고 있다. 폐동맥고혈압이 동반된 그레이브스병 환자가 여러 증례가 보고되었으며, 폐동맥고혈압 환자에게서 갑상선 자가항체와 갑상선기능저하증의 빈도가 높음이 알려지면서 갑상선중독증이 동반된 그레이브스병 환자에게서 관찰되는 호흡곤란의 한 원인으로 폐동맥압 증가가 작용할 가능성이 제시되고 있다. 이에 저자 등은 그레이브스병 환자를 대상으로 폐동맥압을 측정하고 치료 전후의 폐동맥압의 변화를 전향적으로 연구하였다. 방법: 갑상선중독증이 동반된 그레이브스병 환자와 정상 갑상선기능을 나타낸 대조군을 대상으로 갑상선기능검사 및 갑상선 자가항체를 측정하고, 심초음파를 이용하여 치료 전후로 폐동맥압을 측정하여 폐동맥압과 갑상선기능 및 갑상선 자가항체와의 관계, 폐동맥압의 변화 등을 관찰하였다. 결과: 1. 연구대상은 대조군 10명 (남녀비 1:9, 관해 상태의 그레이브스병 3명, 갑상선종 3명, 정상인 4명), 그레이브스병 환자 26명 (남녀비 7:19)이었다. 2. 대조군과 치료 전 그레이브스병 환자의 폐동맥압은 각각 23.5±2.32 mmHg, 29.6±10.3 mmHg이었고, 치료 전의 폐동맥압과 혈청 갑상선자극호르몬 결합억제 면역글로불린 (TBII) 농도는 유의한 양의 상관관계를 보였다. 3. 26명의 그레이브스병 환자 중에서 10명 (38.5%)이 폐동맥고혈압 (기준: 폐동맥압 > 30 mmHg)으로 진단되었다. 4. 치료 전후로 폐동맥압을 측정한 13명은 폐동맥압이 치료 전 29.6±10.3 mmHg에서 치료 후 폐동맥압 22.2±6.48 mmHg로 의미있게 감소하였다. 결론: 갑상선중독증을 보이는 그레이브스병 환자의 약 40% 정도에서 폐동맥고혈압이 발견되어 폐동맥고 혈압은 그레이브스병에 흔하게 동반하는 질환으로 생각된다. 향후 그레이브스병 환자에서 관찰되는 폐동맥압의 증가와 관련한 병인, 발생기전 및 임상적 의의 등에 대한 연구가 필요할 것으로 생각된다. Background: Exertional symptoms, dyspnea and impaired effort tolerance are common in patients with Graves' disease. Proposed explanations include: high-output left heart failure, ineffective oxygen utilization and respiratory muscle weakness. In addition, pulmonary hypertension has also been reported in patients with Graves' disease. A high prevalence of hypothyroidism and positive thyroid autoantibody were also observed in patients with pulmonary arterial hypertension. Therefore, the pulmonary artery pressure in patients with Graves' disease was evaluated. Methods: Two-dimensional and Doppler echocardiographic examinations (Hewlett Packard Sonos 2500) were performed to determine the pulmonary artery (PA) pressure in 26 Graves' disease patients, both before and after treatment (23 patients with propylthiouracil and 3 with RAI), and in 10 euthyroid controls. The changes in the PA pressure after treatment were evaluated in 13 patients with Graves' disease, who became euthyroid after treatment. Results: The pulmonary artery pressure was increased in the untreated Graves' disease patients compared to the normal controls (23.5±2.32 vs. 29.6±10.3 mmHg). 38.5% of the Graves' disease patients (10/26) showed pulmonary arterial hypertension (PA>30 mmHg) and the serum TBII level was higher in the Graves' disease patients with pulmonary arterial hypertension than in those with normal PA pressure (P<0.05). In the Graves' patients who became euthyroid after treatment, the PA pressure was significantly decreased. Conclusion: 38.5% of the untreated Graves' disease patients showed pulmonary arterial hypertension, and the pulmonary artery pressure was significantly decreased in those who became euthyroid after treatment. The pathogenesis and clinical importance of pulmonary arterial hypertension in Graves' disease requires further studies (J Kor Soc Endocrinol 18:465∼472, 2003).

치주질환 심도에 따른 조직내 림프구 및 NK 세포의 변화에 관한 면역조직학적 연구

최호근,이만섭,권영혁 慶熙大學校 齒科大學 1993 慶熙齒大論文集 Vol.15 No.1

케이블 TV 광고의 활성화 방안에 관한 연구

崔永萬 東新大學校 1995 論文集 Vol.7 No.-

In the information age cable television broadcasting is the basis of information superhighway industries. This paper begins with the premise that cable television (CATV) advertising should be activated in order to keep the stable development of CATV. This paper consists of five chapters. Chaper 1 is the introduction, dealing with The objectives and methods of the study. Chapter 2 examines the concept,characteristics,and structure of CATV chapter 3 investigates the present situation and advertising enviroment of CATV in Korea. Chapter 4 comes up with the activating strategies of CATV advertising: the strategies of government and those of advertising industries. Finally, chapter 5 forms the conclusion. I suggest in this paper that the government and the advertising industries should work out these strategies: the government should amend the CATV laws and institutions to activate CATV, lower the deliberation standards of CATV advertising, and support CATV advertising by giving the advertising industries all kind of the possible benefit in tax, finance. The advertising industries should urge program providers to arrange the system interconnects to increase the number of audience, make the use of rational media mix as an advertisement-marketing strategy, and arrange the system-operator interconnects of broadcasting companies to raise the number of subscribers. In conclusion, if the above strategies are effectively put into practice, cable television will certainly attain its stable development through CATV advertising.

웹사이트의 특성과 인터넷 이용성향이 커뮤니케이션 효과에 미치는 영향

최덕철,김영만 慶南大學校 産業經營硏究所 2001 産業經營 Vol.28 No.-

쥐의 성주기에 따른 자궁 비만세포와 성호르몬의 변화

최영자,제갈승주,윤영승,김재만 木浦大學校 基礎科學硏究所 2001 基礎科學硏究誌 Vol.19 No.-

Mast cells reside in connective tissue and mucous tissue that encircle the internal environment of the body, where they mediate inflammatory response encountering foreign materials. Mast cells are also found in uterus tissue which is, in fact, exposed to external world. Because the cells are provoked by invading foreign cells to cause inflammatory response, their response in the uterus should be controled for success in fertilization and implantation, in that the foreign sperms and fertilized egg are willing to invade into the body. In order to confirm such assumption, we investigated the changes in mast cell numbers and their contents in the rat uterus during the estrus cycle and related these to the changes in sex-hormone concentration. The mean number of mast cell at the proestrus and estrus phase was 4.8±2.72 and 5.98±1.55. respectively. The number increased as much as 3 times more then previous phase at the metestrus phase and subsided to half at following the diestrus phase. Those mast cells were subdivided type. Connective tissue type was major at metestrus and diestrus phase. At the following proestrus, however, the muscous type was largely increased and major population was changed to muscous and intermediate type at estrus phase. In the immature uterus of young female, as few as 1.67±0.23 cells were detected and most of them were mucous and intermediate type. The concentration of circulating estradiol-17 β was lowest at the metestrus phase both in free and bound form. The results suggest that estrogen may be involved in inhibiting swarming of mast cells in the uterus and accumulating the contents of secretory vesicles.

Aluminium板의 環境破壞에 關한 基礎的 硏究

崔壯宇,金榮萬,李龍福 弘益大學校 1982 弘大論叢 Vol.14 No.2

It is known that the most of Enviroment Assisted Fracture affected remarkably by the various environmental effect are brittle fracture, and that the above field is very wide. In this paper, Environment Assisted Fracture is discussed from the view point of fracture mechanics. Aluminium and SUS304 Stainless Steel in solutions of several percentage of MgCl₂(10%, 15%, 20%) at the temperature(60℃±3℃)is investigated according to the crack growth, and the value of K is compared with the K obtained by the changes of deflection according to the crack growth. THe results of the experiment is summarized as following 1)The tendency of crack growth as time goes by is shown as 4 region in both materials. 2)The experimental value of K of SUS304 Stainless Steel is same as the calculated value from the variation of the compliance according to crack growth, but not in Aluminium.

小兒 腸重疊症의 臨床的 考察

崔龍萬 梨花女子大學校 韓國生活科學硏究院 1979 韓國生活科學硏究院 論叢 Vol.23 No.-

1973년 8월1일부터 1978년 8월 말까지 만 5년간 이화여자대학교 부속병원 외과에서 치료한 장중첩증환자 62에를 가지고 임상적 및 통계적 분석을 하였다. 장중첩증은 소아의 급성복증 중 가장 흔한 질환이며, 조기에 진단하여 적절한 치료를 함으로써 100%의 완치가 되는 질환이다. 62예를 가지고 연령 및 성별분포, 발병후 내원까지의 기간, 계절별 빈도, 발병원인, 임상증상 및 증후, 검사소견, 방사선소견, 유형별 분포, 치료 및 합병증에 대한 것을 비교 검토하였다. 고찰의 결과 장중첩증은 남아에서 1세 미만에 주로 발병하여 발병되고나서 대부분 24시간 이내에 병원에 오는 것이며, 호흡기 질환이 많은 겨울철에 장중첩증이 많이 발생한다는 연관성을 알게 되었고, 병의 원인은 특발성이며, 이 병의 삼대증상 및 증후군을 대부분 나타내고 있으며,ㅣ ileocecal type이 가장 흔한 형이며, 대부분 수술요법으로 완치가 되었다. Intussusception is the most important and frequent surgical disease in infancy and childhood. This clinical studt was performed on 62 cases with intussusception who were admitted to the Department of surgery, Ewha Womans University Hospital for the past 5 years from August 1973 to August 1978. The following results were otained: 1) In age distribution, the peak incidence was bwtween 6 months and 9 months of age. 51 cases(82.3%) were under one year of age, and the malw tp female ratio was about 3.81:1;males were more affected than females. 2) 40cases(64.5) visited our hospital within the first 24 hours following the onset of symptoms 3) The seasonal distribution showed peaks in summer(25.8%), and the least in autumn(12.9%). 4) The etiology was idiopathic in all cases. 5) The cardina; symptoms and signs were vomiting (90.3%), current jelly stool(85.5%), irritabillty(67.7%) and palpable mass(64.5%). 6) Nimber of W.B.C was most frequent within 10,000~15,00/Cu.mm(46.8%). 7) In the X-ray study, intestinal obstruction signs were manifested in 83.7% with olain abdominal conditions, and intussusception signs were manifested in 89.5% with barium enema. 8) The most common type of itussusception was ileocecal type(48.4%) 9) In the treatment, surgical procedure was performed on 80.6%, of which manual reduction was the most frequent with 86%. Barium reduction was successful in 63.2% of the cases. 10) Among cases admitted to our hospital within 24 hours after the onset of symptoms, postoperative complications occurred in 24% of the cases, with an overall moratlity rate of 3.2%.

고객만족을 위한 고객관계마케팅 운영에 관한 연구

최영만 東新大學校 2003 論文集 Vol.13 No.-

The prosperity of the company requires management techniques and new strategies to accomodate environment changes these days. The clients, one of the most important factors of company's environment, will have interests and fidelity towards the company through interaction of customer's satisfaction. This is called customer relation marketing as well as it is the aim of 21 century's marketing. The researcher focused on how the department industry will gain the competition power and to contribute the development of the department industries. To accomplish this objective, the researcher analyzed the "A" department store and the results of this study are as follows: First of all, " A" department store improved consumer's information power to cope with the time of consumer's right and strengthened the need of management of customer's satisfaction. Secondly, "A" department store targeted the residents who lived at least in the middle size of apartments and used customized relation marketing and target marketing. Thus this system improved the clients' and employees' satisfaction. Thirdly, the basis of the customer's satisfaction management in the "A" department store were based on the effective use of customer's relation marketing which is consist of customer's database system, positioning analysis system, appointment programs with customers, and material handling information system. As a conclusion, the researcher concluded that "A" department store sought the core of customer's satisfaction management as the change of retail environment and customer's spending pattern. This trend accelerates strategic direction of various business forms such as retail store, convenient store, super-market, internet electronic commerce, home-shopping as well as exiting department store. "A" department store also should make an continuous effort to maintain customer relation marketing for customized resource distribution support system and 24 hour customer service through two way communication channel as well as to develop the new marketing strategies.

대구지역 실내 외 공기중 주요 대기오염물질의 농도조사에 관한 연구

최진수,백성옥,김영민,박상곤,정점희,황승만 嶺南大學校 環境問題硏究所 1995 環境硏究 Vol.15 No.1

최근 현대인의 실내거주시간이 일상생활시간의 80% 이상을 차지할 정도로 크게 증가하면서 보건·위생학적 측면에서 실내공기질은 매우 중요한 관심사로 등장하게 되었다. 본 연구는 1994년 8월의 여름철과 1994년 12월 ∼1995년 1월의 겨울철에 대구를 중심으로 가정집, 사무실, 식당과 같은 3가지 유형의 일반주거환경 중 실내·외 공기를 대상으로 실행되었다. 측정항목으로는 RSP, CO, CO₂, NO₂등의 주요 기준성 오염물질과 Bioaerosol을 선정하였다. 본 연구의 결과, 각 성분대상물질의 실내·외 농도는 실내거주환경 및 여름과 겨울, 두 계절에 따라 영향을 받는 것으로 나타났으며 실내·외 농도비교에서 RSP, CO, CO₂의 실내농도는 대부분의 지역에서 실외에 비하여 높은 농도를 나타냈다. 각 실내거주환경에 따른 실내·외의 농도는 가정, 사무실에 비하여 식당에서 상대적으로 높은 농도를 나타냈으며 실내·외 농도비 또한 식당에서 상대적으로 큰 값을 나타냈다. 여름과 겨울의 두 계절에 따른 RSP, CO, CO₂의 실내·외 농도는 여름철에 비하여 겨울철에 더욱 높은 농도를 나타냈으나 Bioaerosol의 실내·외 colony/plate는 여름철에 더욱 높은 수치를 나타냈다. The study was carried out to investigate the concentrations of indoor air pollutants such as respirable suspended particulate (RSP), carbon monoxide (CO), carbon dioxide (CO₂), nitrogen dioxide (NO₂) and bioaerosol at homes, offices and restaurants in Taegu city. Indoor and outdoor concentrations of these pollutants were observed simultaneously from August 1994 for summer to January 1995 for winter. The results were summarized as follows : 1. Both in summer and in winter, the indoor concentrations of RSP, CO, and CO₂; were higher than the outdoor concentrations, the indoor concentrations of major air pollutants (RSP, CO, CO₂, NO₂) in restaurants were higher than those in homes and offices. 2. The indoor and outdoor concentrations of RSP, CO, and CO₂; in winter were significantly higher than those in summer, on the other hand. The CFU/plate of bioaerosol in winter was lower than that in summer. These results suggested that indoor levels of air pollutants were affected by various indoor characteristics such as smoking, cooking, ventilation rate, winter heating systems, and behavioral activity of occupants.