補中益氣湯 투여가 장거리 달리기 선수의 에너지 및 전해질 대사에 미치는 영향 : changes in the energy and electrolyte metabolism among long distance runners

송순기,금동호,오재근,이명종 동국대학교 한의학연구소 1998 東國韓醫學硏究所論文集 Vol.7 No.1

스포츠 과학 분야에서는 운동 선수들의 경기력 향상과 운동 피로의 신속한 회복을 도모하기 위하여 한약을 복용하고 그 효과와 유의성에 대하여 연구가 활발히 이루어지고 있다. 격심한 운동을 수행할 때 나타나는 Glucose 등 에너지원의 고갈, Lactate 등 대사 산물의 축적, 전해질의 불균형 등의 여러 제반 증상이 氣虛로 인하여 나타나는 전신의 증후와 유사하다고 생각하여 補中益氣湯을 투여한 후 인체의 대사 변화를 관찰함으로서 운동수행능력에 미치는 영향과 유의성을 평가하고자 하였다. 본 연구는 장거리 달리기 선수를 대상으로 2주간의 補中益氣湯의 투여가 에너지 대사 및 전해질대사에 미치는 영향을 규명하기 위하여 최대심박수의 70% 강도의 운동을 실시한 후 운동전 안정시, 운동 직후, 휴식 후 10분, 휴식 후 30분, 휴식 후 1시간으로 나누어 혈액검사를 하였을 때 나타나는 각종 변인의 반응 양상을 비교 분석하여 유의한 결과를 얻었다. 혈중 에너지 대사에서는 free fatty acid와 Lactate 반응에서 유의성 있는 차이가 나타났고, 전해질대사에서도 Na^(+), Cl-와 K^(+) 반응에서 모누 유의성 있는 차이를 나타냈다. 그러므로 補中益氣湯은 에너지 및 전해질 대사에서 유의성있는 변화를 나타내었으며 운동수행능력의 향상에 유효하였다. Objective This experimental study was designed to investigate effects of Bo-joong-ik-gi-tang administration among long distance runners on changes of the energy and electrolyte metabolism. Materials and Methods All subjects were divided randomly with two groups, Bo-joong-ik-gi-tang Group (N=4) and control group (N=4) and performed to run the 400m track with 70% of HR max about 1 hour. The blood samples were collected from antecubital vein by 5㎖ syringes at before exercise, immediateIy after exercise, recovering- 10 min, recovering-30 min, recovering-1 hour. These sampie were used to analyze for the factors of the changes on metabolic responses. Firest, the primary factors on the changes of the energy metabolism were checked ; Glucose, Free fatty acid, Lactate, LDH. Second, the primary factors on the changes of the electroIyte metabolisrn were checked ; Na^(+), Cl^(-), K^(+). Results 1. The change of the energy metabolism 1) Glucose response was not shown significant difference between two groups. 2) Free fatty acid response in Bo-joong-ik-gi-tang group was significantly increased at recover-10 min. 3) Lactate response in Bo-joong-ik-gi-tang group was significantly decreased at immediately after exercise, recover-10 min, recover-30 min. 4) LDH response was not shown significant difference between two groups. 2. The change of the electrolyte metabolism 1) Na^(+) response in Bo-joong-ik-gi-tang group was shown significant difference between two groups at before exercise. 2) C^(-) response in Bo-joong-ik-gi-tang group was significantly increased at before exercise, immediately after exercise. 3) K^(+) response in Bo-joong-ik-gi-tang group was significantly increased at recover-10 min. Conclusion According to the above results, it was shown that Bo-joong-ik-gi-tang had the positive effects on changes of the energy and electrolyte metabolism for the long distance runners.

A Study on Optimal Feedback Control of Decentralized Systems

( Lee¸ Dong Gi ) 한국구조물진단유지관리공학회 2002 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.6 No.2

The purpose of this study is to explore optimal output feedback controller for decentralized discrete-time systems. Also, system stability is explored with various approaches. Based on sigular perturbation method, state feedback controller and output feedback controller are applied to stabilize the system.

한국해안으로부터 Purple, Non-Sulfur Photosynthetic Bacterium, Rhodobacter sp. EGH-24의 분리 및 특성

차미선,김기한,조순자,이나은,이정은,이재동,이상준,박재림 한국환경과학회 2003 한국환경과학회지 Vol.12 No.12

A species of facultative photo-organotrophic, purple, non-sulfur bacterium was isolated from the 47 point at west and south coast of Korea in September 2001. Separated 13 samples of changes with red color under 28~32 ℃, 3000 lux, anaerobe conditions for 7 days cultivated in basal medium. For pure isolation from 13 samples, we used agar-shake tube method (0.4 % agar) and separated 5 strains through 13-repetition test. EGH-24 and EGH-30 was identified as the same strain through the RAPD(Random Amplified Polymorphic DNA)-PCR of strain EGH-9, EGH-13, EGH-23, EGH-24, EGH-30. Four isolates cultivated in synthesis wastewater for wastewater biodegradation test. EGH-24 was selected with efficient wastwater treating strain. Based on the results obtained from morphology, nutrient requirements, major bacteriochlorophyll content, 16S-rDNA phylogenetic analysis, EGH-24 strain may be identified as a new strain of the genus Rhodobacter and named Rhodobacter sp. EGH-24.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

Fluoxetine 투여후 발생한 추체외로증후군 3례

이정호,이기철,곽동일,정인과,남민 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.2

The selective serotonin reuptake inhibitor fluoxetine is one of the most frequently prescribed drugs for the treatment of depression and other psychiatric disorders. In the few years, there have been several reports of adverse effects encountered during coadministration of fluoxetine with or without other psychotropic drugs. We experienced three cases of extrapyramidal symptoms were developed when admini-stered fluoxetine alone and with neuroleptics. We conclude that there is a probable or possible causal relationship between fluoxetine and extrapyramidal side effects. The pathogenesis of such adverse reactions, which may be hetero-geneous, is unknown, but it has been suggested that they might be caused by serotonergically mediated inhibition of dopaminergic transmission. From reports in those cases, it appears that fluoxetine alone may be associated with extrapyramidal side reactions. Furthermore the potential for increased levels of concomitant psychotropic medicines and increased side effects, should be borne in mind.

초음파 가이드를 통한 맥락막상강출혈의 치료

이기헌,유재호,김태원,이상준,김신동 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.1

Purpose : Intraoperative suprachoroidal hemorrhage is one of the most serious complications. We report a case of suprachoroidal hemorrhage during phacoemulsification surgery, was managed properly. Methods : Suprachoroidal hemorrhage occurred during phacoemulsificaiton in other hospital. The patient was referred to our department immediately after closing the surgical wound. On initial examination, iris and vitreous were prolapsed through surgical wound. Ciliary body was closely place to anterior chamber, and retina was not visible. Results : Prolapased ocular tissue were reduced by emergency operation. We controlled the patient’s intraocular pressure and inflammation. Ultrasonography was repeatedly performed to check the degree of liquefaction of suprachoroidal hemorrhage. After 9 days of suprachoroidal hemorrhage onset, vitrectomy and drainage through sclera was performed. Postoperative state was stable with successful removal of suprachoroidal hemorrhage. After 2 weeks of secondary operation, retinal detachment has occurred on nasal retinal area, so we performed scleral buckling and endolaser photocoagulation. After 6 months, retina was attached well and intraocular pressure was in normal range. Conclusion : In suprachoroidal hemorrhage, drainage of suprachoroidal hemorrhage after liquefaction of thrombi is effective. After successful drainage, postoperative complications may accompany such as retinal detachment or elevation of intraocular pressure. 목적 : 술중 발생하는 맥락막상 출혈은 매우 심각한 합병증이다. 저자는 수정체 유화술 중에 발생한 맥락막상 출혈을 적절히 대처한 증례를 보고하는 바이다. 대상과 방법 : 수정체 유화술 중 발생한 맥락막상강 출혈환자가 수술창을 봉합 후 즉시 본원으로 전원되었다. 초진시 홍채와 유리체가 수술창을 통해 탈출되어 있었으며, 전방을 통해 모양체가 확인되었으나, 망막은 보이지 않았다. 탈출된 안구내 조직을 응급수술을 통해 복원 후 환자의 안압과 염증을 조절하였다. 초음파를 반복적으로 실시하여 맥락막상 출혈의 액화 정도를 확인하였으며, 출혈 9일 후 유리체 절제술과 공막을 통한 배액술을 시행하였다. 결과 : 맥락막상 출혈이 성공적으로 제거되었으며 술 후 상태는 안정적이었다. 수술 2주 후 비측 망막 박리가 발생하여 공막돌륭술과 안구내 삽관 레이저술을 시행하였다. 6개월 후 망막은 잘 붙어있었으며, 안압은 정상 범위를 유지하였다. 결론 : 맥락막상 출혈의 경우 출혈의 배액 시기를 결정하는 것이 어렵지만, 규칙적인 초음파를 통해 배액술의 시기를 결정할 수 있다. 또한 맥락막상강 출혈의 성공적인 배액 이후에도 망막박리 및 안압상승과 같은 합병증의 동반에 대해 유념해야한다.

지연시간의 개념확장과 그 응용

이기동 안동대학교 기초과학연구소 1997 基礎科學 硏究論文集 Vol.8 No.1

In order to investigate geological structure, seismic method is the most widely used among geophysical methods. We can easily and briefly prove basic formulas for refractive method by using the broad sense of delay time.

섬유강화 고분자 복합판의 기계적 성질에 미치는 섬유길이와 섬유함유율의 영향

이상동,김혁,허업,최종대,이동기 조선대학교 에너지.자원신기술연구소 1997 에너지·자원신기술연구소 논문지 Vol.19 No.2

This paper describes effect of chopped strand length fiber content and moisture absorption on mechanical properties of fiber-reinforced polymeric composites. It was extrusion compounded long fiber-reinforced polypropylene containing 20, 30 and 50 percent and short fiber-reinforced ABS and PAS containing 30 percent b37 the weight of glass fiber. The test methods of ASTM D638, D3410-87 and D79OM are applied for tensile, compressive and bending tests respectively. The results show that, in the case of 0.2% moisture absorption, the residual strength decreases dramatically.

항결핵 치료과정에서 호전되었다가 악화된 뇌 결핵종 1예 보고

이대훈,유진홍,강미자,김홍기,김선화,고동훈,천지성,유원종 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.3

In spite of nationmide tuberculosis control program, tuberculosis is still prevalent in Korea. Accordingly, tuberculous meningitis also poses one of the main trouble some problems. Recently, We experienced a perplexing case of tuberculous menin-gitis and tubercdoma in a 24-year old female patient. She was admitted to our hospital owing to meningeal irritation sign, aphasia, VI nerve palsy, and ,fever. CSF analysis showed a finding consistent with that of presumptive tuberculous meningitis.. Initial MRI of the brain revealed a large mass(tuhercu1oma) on left parieto-temporal area. Antitubeculous regimen(1soniazid (INH), rifampin(RMP), ethambutol(EMB), pyrazinamide(PZA)} of meningeal dose was given immediately, and her symptoms and signs were dramatically disappeared with a few days after treatment. She was discharged with improved condition and under maintenance treatment of tuberculosis. Follow-up one year after treatment. revealed that the previous lesion was nearly diminished. She showed no symptom at all until she recognized a total blindness of sudden onset on her left eye a t the 18th month of treatment. Brain MRI checked at that time showed multiple masses of tuberculoma scattered over the brain base and one of them invaded left optic nerve. In our opinion, the cause of relapse in this patient might he explained by the selection and ultimate replication of a minor population of resistant strain. Although such relapse is an extremely rare event, we think that we should always pay attention to this possible resistance problem every time we meet patients with tuberculous meningitis.

급성 백혈병 관해유도요법후 발생한 다발성 비장농양 1예

이홍기,김선운,박경동,이현성,주영돈,손창학 인제대학교 2000 仁濟醫學 Vol.21 No.1

Splenic abscess is a rare illness. Its incidence has ranged from 0.14 to 0.7 % in various autopsies conducted in the US. Even in the most recently published articles, diagnosis was made only in autopsies in 37 % of the cases. While splenic abscess may arise occasionally from contiguous spread of infection or direct trauma to the spleen, usually it develops with hematogenous spread or infection. But, bacterial endocarditis is the most common cause. RUQ pain of abdomen developed in only half of series. Splenomegaly, fever and leucocytosis was also present. When splenic abscesses are being considered in a differential diagnosis, CT scan of the abdomen has been the most sensitive diagnostic tool. Streptococcal species are the most common bacterial isolates from splenic abscesses, S. aureus is the next most common. Salmonella species are seen commonly in patients with sickle cell hemoglobinopathy. Because of the high mortality related for splenic abscess, the treatment of choice is splenectomy with adjunctive antibiotics. However, percutaneous drainage has been successful alternative. We reported a 19-years old female patient who had splenic abscess after remission induction chemotherapy of acute leukemia, successfully treated with splenectomy.