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이현성,최우진,고영초,이채혁,박효일 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5
Objectives : In this study, the author reviewed the clinical features of the patients with anaplastic oligodendroglioma and evaluated the efficacy of surgery, radiation therapy and chemotherapy as a treatment modality. The study was intended to provide the standardized treatment option for this rare disease. Methods : The author present ten cases of pathologically proven anaplastic oligodendrogliomas from 1988 to 2002. A retrospective analysis of clinical presentation. radiological and pathological features, and the effectiveness of treatment was performed and the factors affecting prognosis were investigated. Fesults : The ten patients comprised of four males and six females. The mean age at diagnosis was 34.4 (8-70). The mean follow-up duration was 40.5 months. and two patents died of tumor progression during the follow-up(70, 86 months, respectively). The most common presenting symptom was seizure(70%). All patients underwent surgery and the tumors were removed as much as possible. Postoperatively, Radiation therapy was applied to seven patients. and PCV(procarbazine CCNU-vincristine) based chemotherapeutic agent was administered to five patients. Total removal was achieved in five cases and subtotal removal was possible in the rest. In the group with PCV therapy, complete remission was observed in two, partial remission, stable disease, and disease progression to death in one, respectively. The patients well tolerated the toxicity of chemotherapy. During the follow-up, tumor recurrences were observed in four patients, and they were treated with additional operations and/or chemotherapy. Mixed anaplastic oligoastrocytoma showed earlier recurrence than anaplastic oligodendrogliomas in this study(P=0.014), but the other clinical factors and treatment modalities were not related to the time of recurrence of the tumor. Conclusions : In this study, the authors confirmed the good response of postoperative radiological treatment and chemotherapy in patients with anaplastic oligodendroglioma. PCV chemotherapy should be considered as primary treatment method for the patients with anaplastic oligodendroglioma.
수에즈막스 탱커의 탑브레이싱에 따른 선체 진동 영향 연구
이현성,조윤성,김영남 대한조선학회 2011 대한조선학회 학술대회자료집 Vol.2011 No.11
Long stroke and low speed diesel engines with six or more cylinders have a likelihood of vibration problems related with resonant response of engine due to the guide force moment which can causes H-mode and X-mode vibration. Top bracings are installed between the main engine and the hull structure to reduce the dynamic vibrating characteristics of the onboard engine body and coupled effect on ship structures. Without considering a natural frequency of coupled main engine and ship hull structures, installation of top bracings can deteriorate the vibration problems. In this study, a resonant response of engine and global ship structures with and without top bracings was evaluated using a global vibration analysis by finite element models (FEM). The resonant response from global vibration analysis (FEM) is compared with a measured resonant response during sea trials. The results showed that the top bracing controls a natural frequency of engine and coupled hull structure to avoid a critical vibration. In addition to the evaluation of resonant response, guideline for installation of top bracings on specific type engine (MAN B&W 6S70MC engines) of suezmax tankers is suggested.