Anti-osteoporotic Effects of Sericin-Calcium Conjugate in Ovariectomized Rats

Ehn-Kyoung Choi, Dongsun Park, So-Young Choi , Yun-Hui Yang, Seock-Yeon Hwang, Seongho Yeon, Jeong-Yong Lee, Ill-Hwa Kim, Yun-Bae Kim, Hyun-Gu Kang1 충북대학교 동물의학연구소 2011 Journal of Biomedical and Translational Research Vol.12 No.2

This study was conducted in order to evaluate the effect of sericin-calcium (SC) as therapy for ovariectomy-induced osteoporosis in rats. Three weeks after ovariectomy (OVX), Sprague-Dawley rats were divided randomly into three groups: sham-operated group (Sham), ovariectomized group, and SC-treatment group (OVX+SC). Rats in the OVX+SC group were given drinking water containing 0.07% SC for eight weeks. Bone breaking force, mineralization, and blood parameters related to bone metabolism were analyzed. In OVX animals, blood concentration of 17β-estradiol showed a significant decrease, while osteocalcin and type I collagen C-terminal telopeptides (CTx) showed an increase. Breaking force of femurs as well as bone mineral density (BMD), ash, calcium, and phosphorus in femurs showed a significant decrease following OVX. Treatment with SC (0.07% in drinking water) resulted not only in remarkable restoration of the decreased 17β-estradiol and increased osteocalcin and CTx concentrations, but also led to recovery of decreased femoral breaking force, BMD, ash, calcium, and phosphorus. It is suggested that SC effectively improves bone density by preventing bone turnover-mediated osteocalcin, CTx, and minerals, and that it could be a potential candidate for use in therapy or prevention of post-menopausal osteoporosis.

경남지방의 향토요리에 관한 연구 : 탕류를 중심으로

김경자,강선희,곽연주,김명진 한국조리과학회 1990 한국식품조리과학회지 Vol.6 No.3

Currentry, the originality of traditional soups in Kyoung-Nam province is vanishing by the inflex of processed and instant food, food industrial development. Especially, such factors as the influence of alien cooked, the develoment of transportation, the movement of population have made it hard to preserve the traditionnal food preparations. The purpose of this thesis was to seek out the various kinds of Kyoung-Nam province soups preparation. To do this, about 60 kinds of soups recipe were reviewed and charactered into several categories. The findings of the study are as follows. 1) Soup is made by fish or shellfish, freshwater fish. Meat and fowls is rarely used in Kyoung-Nam province (coastal region). 2) Soups of inland area is made by most vegetables and these soup were always harmonized with soybean powder or perilla powder. 3) Various soup season with the mag-jang, mul-jang sauce, hab-ja-jang sauce. 4) These soups were in general to make much red pepper and much salt.

오존공정을 이용한 염색폐수의 처리특성에 관한 연구

강용태,원태준,한상윤,고영발,박경덕 東亞大學校 建設技術硏究所 2008 硏究論文集 Vol.32 No.1

The wastewater from textile industry typically containing high alkalify, salts, organic matter, and high color. Textile wastewater is usually treated by anaerobic-aerobic activated-sludge process. The activated-sludge process is effective the reduction of organic matter, but generally does not remove color. Ozone process is one of the most effective process in removal of color for the textile wastewater. Ozone has a strong oxidized dissolution of organism, deceleration, deodorization, fumigation, etc., regarding to water. This study focused on the color removal of textile wastewater. In this study, textile wastewater was treated strongly with ozone at 650mg/hr and the flow rate through ozone contact tank was adjusted to 5L/min. In an application Ozone treatment, Color was generally decreased with time, however, COD removal effect was not that good. In this study, the removal efficiencies of CODcr and Color were 23.5%, 80.4% respectively.

DBME(Discipline-Based Music Education)에 의한 음악과 교육과정의 비판적 분석과 발전 방향 탐색

최윤경,강현석 이화여자대학교 사범대학 교육과학연구소 2005 교육과학연구 Vol.36 No.2

오늘날 음악 교육은 입시 위주의 교육 정책, 국가 경쟁력의 강화라는 표어 아래에서 학교 당국과 교사, 학생, 학부모에게 부담스러운 과목으로 외면당하고 있으며, 음악 교육의 가치와 당위성마저 흔들리는 위기에 직면해 있다. 이러한 위기는 현재까지의 음악 교육이 일반적으로 ‘음악 이론과 기능을 가르치고 음악 활동을 하는 교과’로 인식되어 왔고, 음악과 교육과정 역시 ‘이해해야 할 지식’과 ‘경험해야 할 행위와 활동’을 단순히 나열하고 있었기 때문이라고 할 수 있다. 우리나라와 비슷한 위기에 직면했던 미국은 예술 교육의 정상화를 위해 미술교육에서 DBAE(Discipline-Based Art Education) 이론을 개발하였고, DBAE의 연구 결과에 기초하여 음악 교육의 문제를 해결하고자 연구된 것이 DBME(Discipline-Based Music Education)이다. 이에 본 연구는 DBME의 역사적 배경, 목적과 내용, 특징을 살펴보고, 이를 통해 현행 음악과 교육과정을 비판적으로 분석하였으며, 향후 음악과 교육과정이 ‘사회적?역사적?문화적 맥락을 고려’하고, ‘사고와 탐구 활동을 강조’하고, ‘디지털 중심의 사회적 변화를 수용’하는 음악과 교육과정으로 발전하여야 함을 제안하였다. Today, music education is a burden to teachers, students and parents and music is recognized to difficult subject. The reason is why the purpose of education changes into the university entrance and the policy of economic growth has precedence. So, The value of music education have faced at risk. The reason is that music education was recognized by subject matter that teaches music theory and function and does music activity until now. And music curriculum lists knowledge to understand, and activity to experience. The United States of America that faced at risk similar our country developed DBAE(Discipline-Based Art Education) theory in art education to solve problem of art education. DBME(Discipline-Based Music Education) is based on DBAE and studied to solve problem of music education. DBME involves music-making, musical history, musical aesthetics and musical criticism. Each of these disciplines are related and integrated to provide students with a balance understanding of works of music. This study examines historical background, purpose, contents, characteristic of DBME for theoretical explanation. Through this, current music curriculum is analyzed critically. And the direction of music curriculum is presented as following. So Music curriculum that accommodates engineering, considers social, historical, cultural context, and emphasizes thinking ability is emphasized in the next music curriculum revision.

지역사회 기혼 여성의 우울 증상에 영향을 미치는 변인 : 가족내 관계 만족 변인 및 갈등대처 방식을 중심으로

이경미,최윤경,강이헌,이민수 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.2

연구목적 본 연구는 지역사회 기혼 여성의 우울 증상을 사회적이고 대인관계적 측면에서 이해하고자 하는 맥락에서 살펴보고자 하였다. 방법 00시에 거주하는 기혼여성 632명을 대상으로 하여 Beck 우울증 척도, 결혼 전반적 불만족 척도, 자녀불만족 척도, 갈등 대처 방안 척도 등을 실시하였다. 통계방법으로는 기술통계분석, 상관, χ²검증, 일원변량분석, 단계적 중다회귀분석, 위계적 회귀분석을 사용하였다. 결과 학력, 수입, 부모의 관계, 학대경험, 시부모 관계만족, 결혼불만족, 자녀불만족, 이성적 대처, 감정 · 행동표출, 회피 행동에서 우울수준에 따른 집단간 차이가 유의미하였다. 또한 이들 변인 중 결혼불만족이 현재 우울증상에 대한 설명력이 가장 큰 것으로 나타났고, 다음으로 자녀불만족, 회피 행동, 시부모 관계만족 순이었다(총설명변량=36.1%). 갈등대처방식 중 이성적 대처와 회피가 가족관계 만족변인과 우울을 잠정적이지만 유의미하게 매개하는 것으로 나타났다. 결론 지역사회 기혼 여성의 상당수가 우울 증상을 경험하고 있어 이에 대한 치료적 개입이 시급하며 특히 부부 관계를 포함한 가족 관계에 대한 탐색 및 접근이 필요한 것으로 나타났다. 특히 갈등대처방식이 유의미하게 관계 만족과 우울을 매개하므로, 우울증의 치료에 있어 효과적인 갈등 대처 방식 및 사회적 문제 해결 기술을 포함시킴으로써 치료 효과를 높일 수 있을 것으로 시사된다. Objectives : The purposes of this study were to investigate depressive symptoms among married women and to their Understand depression through social and interpersonal factors. Methods : The subjects were consisted of 632 married women who lived in 00 city. They completed the Beck Depression Inventory, Marital Global Distress Scale, Dissatisfaction with Children Scale, and Conflict-coping Method Scale. Descriptive statistics, correlation, χ²-test, ANOVA, step-wise regression, and hierarchical regression were applied to analyze the data. Results : ANOVA analysis showed the differences in education, income, experience of abuse, parent-in-law relationship, marital global distress, dissatisfaction with children, rational coping, emotion/action-expression coping, and avoidant coping among the non-depressive group, mildly depressive group, and depressive group. Step-wise regression showed that the variance of the current depressive symptoms was accounted for by marital global distress, dissatisfaction with children, avoidance coping method, and satisfaction with parent-in-law (total account=36.1%). It was found that the rational coping method and avoidance coping method significantly mediated the relationship between the satisfaction with family relation and depressive symptoms. Conclusion : Therapeutic interventions for the married women experiencing depressive symptoms showed include their marital relationship. Based on the finding that the conflict coping methods mediated the association between the depressive symptoms and the family relation satisfaction, the effective conflict coping skills or social problem solving skills should be included in the interventions for married women.

절수에 의한 mongolian gerbil의 체중 변화에 관한 연구

이경열,송치원,김무강,조성환,류시윤,김상근,박배근 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

Recently, the mongolian gerbils have been used in neurology and the study of water metabolism because of their easy onset of epileptic seizure and typical resistance to water deprivation. The sebaceous glands which are under the control of the gonadal hrmones are differently developed from the other laboratory animals. However the physiological data on the changes of body weight following water deprivation in mongolian gerbils is not available until now. In order to investigate the effect of the water deprivation on the body weight, the animals were deprived of water for 15 days. The body weights were measured daily by the torsion balance. The mean, the standard deviation, the standard error and the coefficient of variance of the body weights were calculated. The correlation was examined. The potential regression equation was y = 61.5458 - 2.0533 * x + 0.0487 * x^2. The regression coefficient was 0.993. The results obtained were as follows : 1. The body weights of the mongolian gerbils were continuously decrased from the 1st day to the 15th day after the water deprivation. 2. The mean body weight on the water deprivation was 63.0±7.00g and that at the 15th day was 41.4 ± 5.42g. 3. The coefficients of the variance showed the highest (13.09) at the 15th day and the lowest (10.10) at the 10th day. the coefficients of the variance kept decreasing until the 10th day and thereafter gradually increased until the 15th day. 4. The changing rate of the body weight kept continuously decreasing from the 1st day to the 15th day showing the daily loss of 1.0 - 3.3%. 5.The deviations (M - QBW) between the measured values (m) and the theorical values (QBW) using the regression equation showed the highest (1.494) at the 1st day and the lowest (0.053) at the 13th day. 6. The sum of the devitions was 0.179 and that of the deviation square was 1.15. The sum of the deviation rates between the mesaured body weights and the theorical ones was 0.484. 7. The daily body weight loss showed the highest at the 1st day by 2.053g and the lowest at the 15th day by 0.591g. 8. The specific body weight changing rates which were the rate of the body weight changing velocity to the changed body weight were decreased from 0.033% at the 1st day to 0.014% at the 15th day.

등척성 운동 시 요추의 각도에 따른 중앙주파수와 토크의 특성

박경희,권오윤,장근,강성재,김영호 한국전문물리치료학회 2001 한국전문물리치료학회지 Vol.8 No.2

Fatigue is the decline in force produced as a result of prolonged muscle activity. Localized muscle fatigue can be identified by a shift toward low in the frequency components of the EMG signal, typically represented by a fall in the median frequency. Previous studies show that a shortened muscle developes a higher fatigue than elongated muscles. The purpose of this study was to investigate the time-related change of median frequency and torque during maximal isometric back extension exercises at different exercise angles (0˚, 12˚, 36˚, 72˚). Twenty healthy subjects (mean age = 24.35 ± 2.70) were evaluated in this study. Median frequency was extracted from the EMG signals by fast Fourier transform (FFT). Initial median frequency and the slope of median frequency change over time were computed from linear regression analysis. Pearson's product moment correlation was used to quantify the relationship between scope of median frequency and torque. The results were as follows: 1) Significant differences in y-intercepts of torque regression equation with respect to exercise angle were shown. However, there were no differences in the slopes of the median frequency and torque, and y intercept of the median frequency among exercise angles. 2) There was no significant correlation between slope of median frequency and torque. 3) But there was moderate correlation between median frequency and torque at each exercise angle. In conclusion, the exercise angle during maximal isometric back extension exercise is not a direct effect on slope of median frequency and torque. But results showed that median frequency and torque shift were highly correlated in all subjects.

의복스타일과 색상·톤조합이 인상형성에 미치는 영향

김윤경,강경자 한국의류학회 2003 한국의류학회지 Vol.27 No.3,4

The Purpose fo this study is to find out the effect of clothing style and color, tone combination on impressions formation. The experimental materials developed for this study are a set of stimuli and response scale(The 7-point semantic). The stimuli are 36pictures manipulated with clothing style, color and tone variation by computer drawing. The subjects are 216 female undergraduate students and 216 female of middle age(40~50) in Chin-ji city. The resulte of this study are as follows ; Impression factor of the stimulus was consisted of the 5 different demensions(attractiveness, elegance, activity, revealation, tendemess). Among there, attractiveness and elegance factors proved to be more important. In the attractiveness and tenderness, clothing style, color, tone combinations and perceiver's age had the significant effect. In the elegance and revealation, color and perceiver's age had the significant effect but in the activity, only color did not have the significant effect. Significant interaction effects of clothing style and color, style and tone combination, and color and perceiver's age on attractiveness and revealation were found. Interaction effect of color and tone combination was significant on the elegance and revealation, and that of color and perceiver's age was significant on tenderness.

Apolipoprotein E 다형성에 따른 사업장 근로자의 혈중 지질농도, 영양소 섭취 및 건강관련 생활습관

박유경,조상운,강지연,백윤미,성숙희,최태인 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.5

The purpose of this study was to investigate the association among nutrient intakes and health-related lifestyles with cardiovascular disease risk assessed by blood lipid profile according to Apolipoprotein E genotypes. Middle-aged industrial male workers who had completed their annual medical examination were recruited and data of 675 subjects who finished the nutrient survey were used in the analysis. Anthropometric parameters, dietary assessment (FFQ), health-related lifestyles and blood profiles were used for statistical analyses. Apo E genotype groups were classified into the following three genotypes: Apo E2 group (including E2/E2, E2/E3, E2/E4), Apo E3 group (including E3/E3), Apo E4 group (including E3/E4, E4/E4). The frequency of Apo E2, E3, and E4 allele were 13.3%, 75.0% and 11.7% respectively. There were no significant differences in the anthropometric parameters depending on different Apo E genotypes. Also, no significant differences in the nutrient intakes were found according to the genotype groups. The nutrient intakes of all subjects were similar to or higher than the level of KDRIs (Dietary Reference Intakes For Koreans) except for intakes of calcium (67.44% of KDRIs), vitamin A (73.83% of KDRIs) and vitamin B2 (78.02% of KDRIs). Also, there were no significant differences of health-related lifestyles according to Apo E genotype groups. As for the lipid profiles, Apo E4 group had significantly higher total and LDL-cholesterol concentrations than the Apo E2 group (p < 0.05). We confirmed that plasma total and LDL-cholesterol concentrations were greatly influenced by Apo E genotypes. However, nutrient intakes and health-related lifestyles were not associated with Apo E genotypes.

장치 및 미디어 관리를 통한 네트워크 기방 백업 및 복구

복경수,강태호,윤종현,유재수 충북대학교 컴퓨터정보통신 연구소 2005 컴퓨터정보통신연구 Vol.13 No.1

저장 매체의 대용량화가 가속화되면서 대용량의 데이터를 효과적으로 백업하기 위한 요구가 증가되고 있다. 본 논문에서는 네트워크 장치 및 미디어 관리를 통해 네트워크 기반 백업 및 복구를 지원하는 백업 소프트웨어를 설계하고 구현한다. 제안하는 백업 소프트웨어는 디스크 기반 백업을 지원하기 위해 NDMP 프로토콜을 확장한다. 제안하는 백업 소프트웨어는 전체 또는 부분 백업, 수동 또는 자동백업 기능을 제공한다. 또한, 사용자에 의해 요청되는 부가적인 작업을 처리하기 위해 pre/post 스크립트 기능을 제공한다. 제안하는 백업 소프트웨어는 백업 장치 및 미디어를 효과적으로 관리하고 이를 풀(pool)이라는 논리적인 단위로 관리하는 장치 및 미디어 관리 기능을 제공한다. As the size of storage media is growing, the efficient backup for the huge capacity data are required. In this paper, we design and implement the backup software that supports network based backup and restore with management of network devices and media. The proposed backup software extends NDMP protocol for the disk to disk backup. In addition, the proposed backup software has various features such as partial or full backup, immediate or automatic backup, and so on. It supports pre/post script to process additional actions for users. It also provides devices and medium management features that efficiently manages a large number of backup devices and media, and groups devices and media management functions that are managed by logical units called pools.