일과성 전 기억상실증으로 나타난 크로이츠펠트 : 야콥병 1례

신대수,이승희,이한샘,박성욱,박현영,장혁,장성조,김요식,조광호 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.1

운동실조를 동반하지 않은 급성외안근마비 1례

신대수,이승회,이한샘,박성욱,박현영,장혁,김요식,조광호 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.2

양성갑상선종물 환자에서 갑사선 호르몬 억제요법과 갑상선 호르몬과 항갑상선제 병합요법의 치료효과 비교

최성남,공병호,배현철,오연상,신순현 중앙대학교 의과대학 의과학연구소 1998 中央醫大誌 Vol.23 No.1

Traditionally, patients with nontoxic benign thyroid nodule has been treated with levothyroxine. The successful treatment of T4 suppressive therapy, however, has been observed in 50 % of patients with thyroid nodules oven though the treatment were continued more than 1 year. The side effects such as osteoporosis, left ventricular hypertrophy has been observed. Therefore, we performed this study to evaluate the efficacy of the new treatment modality (levothyroxine and methimazole combination) in the treatment of thyroid nodule. Study population was 67 patients having nontoxic benign thyroid nodule. Serum TSH, fT4, T3 and thyroid nodular volume were measured at pretreatment and post-treatment periods. The benign thyroid lesion was confirmed by FNAC (fine needle aspiration cytology). The factors can be influenced on therapeutic response were also studied. The patients were divided into two groups. One group had been treated with levothyroxine only and the other with levothyroxine and anthithyroid drug combination. 47 patients had been treated with levothyroxine only. The other 20 patients had received combination therapy with levothyroxine and methimazole. The mean age and sex ratio, pretreatment nodular volume, TSH, fT4 and total T3 level measured at pretreatment and post-treatment had no stastistical difference between two groups. The combination therapy group had been treated for 8.4 ± 2.6 months and T4 suppressive therapy group for 11.1 ± 4.8 months (P=0.03). Pretreatment TSH concentration was 0.99 ± 0.60 μIU/ml in T4 suppressive therapy group, 1.43 ± 1.21 μIU/ml in combination therapy group. (P=0.023) But the value of serum TSH in both groups was in normal range. The responder group was 17 patients and the response rate was 85 % in combination therapy group and 25 and 53 % in T4 suppressive group. In the combination therapy group, the volume reduction was more greater. (71.5% in combination group, 18.1 % in T4 group) In conclusion, combination therapy can reduce treatment duration, enhance therapeutic response rate for the treatment of benign thyroid nodule. The exact mechanism of methimazole on thyroid nodule wan not not clearly known. Perhapse, the influence of methimazole on the transcription factor may be involved Further study in this regard is needed in the future.

초등학교 수준별 교육과정 운영 방안에 관한 연구

이성영,김광명,신준식 춘천교육대학교 초등교육연구소 2001 敎育硏究 Vol.18 No.-

文化變遷에 따른 精神疾患 槪念 및 治療法에 관한 見解調査

金光日,元鎬澤,李正浩,申榮宇,金允姬,朴宗學,崔圭珙,洪性彦 大韓神經精神醫學會 1975 신경정신의학 Vol.14 No.4

Opinion about the cause and desirable way of treatment of mental illnesses, psychoses and epilepsy, were collected from 379 rural peoples and 201 peoples in Seoul city by individual informal interviews. Purposefully, the interview were limited to old people over 50 year of age who were resident in the rural areas with traditional way of life, and to the relatively civilized peoples who had been resident in Seoul for the past ten years. The results from the two sources were compared and discussed from the point view of acculturation. It was obvious that the concepts in cause and treatment of mental illnesses was shifted from the primitive orientation to the modern one. Shamanistic and primitive medicinal concepts were almost neglected in Seoul sample, whereas the two concepts were definetely high as 53.2% for psychoses, 88.3% for epilepsy in rural sample. Seoul sample unexpectedly revealed high psychological orientation to the causs of psychoses and even to the cause of epilepsy as 88.5% and 17.6% each. On the other, rural sample manifested the psychological orientation to the cause psychoses and epilepsy as 46.8% and 3.4% respectively. Way of treatment was also evidently changed; supernatural and primitive medicinal treatments for the mental illnesses were scarcely adviced by Seoul people, whereas the two treatments were adviced by the rural people in 44.5% and 18.6% each for the psychoses, and 4.4% and 63.4% for the epilepsy. Folkpsychological way of treatment for the psychoses was 61.7% in Seoul, 20.0% in the rural area. Even for the epilepsy, this psychological treatment was 22.2% in Seoul, 2.5% in rural area. Opinion about the efficacy of modern medicine in the treatment of mental illnesses was still negative. Favorable result of modern medical approach for the psychoses could be expected only in 28.6% of Seoul sample, 8.9% of rural sample. That of modern medical approach for the epilepsy could be only in 36.4% of Seoul sample and 10.5% of rural sample. Seoul sample responded to the psychoses as "curable" in 59.3%, but rural sample did in 20.2%. For the prognosis of epilepsy, Seoul sample responded as "curable" in 27.4% and rural sample only in 3.0%. It was impressed that the concept and way of treatment of mental illnesses were apparently changing from the primitive to the civilized by acculturation process. Two kinds of problem would be suggested. One is a discrepancy between concept and real attitude. Seoul people are interestingly enough to have desirable conceptual change of mental illnesses, while they frequently practice shamanistic and primitive medicinal approaches. By such reason, it would be likely that the conceptual acculturation would be the initial step to change, and attitudinal acculturation would be clearly later. The attitudinal acculturation is still intermingled with primitive and modern approaches. Another problem is poor expectation to modern medicine in the treatment of mental illnesses. Prognositc view is also not so favorable as expected, even the Seoul sample is more favorable than the rural is. Furthermore, they, both Seoul and rural peoples, have various kinds of psychological or folkpsychological causes and treatment. This tendency is more prevalent in Seoul. These patterns easily suggest a difficulty of secondary prevention in Korea.

무방류식 자연발효화장실에서 배양가능한 혐기성 세균

이관복,신광수,박성주 대전대학교 기초과학연구소 2002 自然科學 Vol.13 No.1

혐기성 소화 방식으로 분뇨를 처리하는 무방류식 자연발효화장실의 혐기성 세균을 연구하기 위하여 모형 화장실을 제작 가동하면서 혐기성 소화가 일어나는 발효조의 분뇨를 채취하여 모두 19개의 혐기성 세균 균주를 순수 배양하였다. 이들에 대하여 생화학적 특성을 조사하였으며 이를 기초로 한 표현형적 동정과 이와 동시에 165 rRNA 유전자의 염기서열 분석으로 동정을 실시하였다. 19개의 분리균주 가운데 3개는 분뇨의 주성분인 탄수화물 분해능이 거의 없었으며, 8개는 15℃에서도 생장 가능하였다. 표현형 및 유전자 동정이 모두 실시된 10개의 균주가 동일한 동정 결과가 나타난 것은 하나도 없었다. 유전자 동정 결과 9개가 Low G+C gram-positive bacteria 즉 Bacillus/Clostridium group에 속하였으며 이 가운데 8개가 Enterococcus 속이었다. The model human manure digestion tank without effluent was constructed and operated for studying anaerobic bacteria participating in anaerobic digestion of human manure. A total of 19 anaerobic bacterial pure isolates were obtained from human manure samples in the digestion chamber. Their phenotypic characteristics were examined by various biochemical tests, by which the isolates were identified. In addition. their genotppic identification were carried out by the 16s rDNA base sequence analysis. Three culturable isolates did not ferment carbohydrate compounds which are main constituents of human manure. Eight isolates grew at 15-C. None of ten showed the same identification results by phenotypic and genotypic tests. The 16s rDNA base sequence analyses showed that nine isolates of ten belong to Low G+C gram-positive bacteria, and eight of which belong to genus Enterococcus.

천공성 환상 육아종

성용기(Yong Kee Seong),조광현(Kwang Hyun Cho),김선훈(Seon Hoon Kim),이유신(Yoo Shin Lee) 대한피부과학회 1986 대한피부과학회지 Vol.24 No.5

We present a case of perforating granuloma annulare which appeared as multiple small papular lesions with central umbilication on the dorsum of both foot and sides of foot, The patient was a 12 year-old female child who had slightly tender lesions of one month's duration. Histologic study showed perforation of the epiderrnis and release of the abnormal necrobiotic material transepiderrnally. The epidermal perforation communicated with area of granuloma annulare in the dermis that consist of necrobiotic collagen surrounded by palisading mononucler phagocytes in the dermis. All the lesions resolved spontaneously with a slight hyperpigmentation in 4 months. She also had erythematous tender nodules, which diagnosed as erythema nodosum, on both shins. The lesions responded to potassium iodide 1.0g for 2 weeks.

부산 경남지방에 발생한 쭈쭈가무시병 64예의 임상적 고찰

이상훈,전명호,신병철,박기찬,김영효,배성,전광수,김종성 동아대학교의과대학 1992 동아의대학술지 Vol.4 No.1

Exploring the Effects of the Virtual Human with Physicality on Co-presence and Emotional Response

Kwang-Seong Shin(신광성),Dongsik Jo(조동식) 한국컴퓨터정보학회 2019 韓國컴퓨터情報學會論文誌 Vol.24 No.1

With continued technology innovation in the fields of computer graphics (CG) and virtual reality (VR), digital animated avatars (or virtual humans) are evolving into ones that are more interactive at a suitable location such as museum, airport, and shopping mall. Specially, the form of the avatar (or the virtual human) realistically need to be expressed in a way that matches the users’ physical space. In recent many researches, the form of virtual human has been expressed as mixed-reality human (MRH)-the virtual human combines with the physicality as the real part. In this paper, we propose to carry out a study comparing various MRH on co-presence and emotional response in two-typed virtual humans depending on how many actual parts are included: (1) (Level 1) small parts in the virtual human combined virtual components (e.g., the head only) and (2) (Level 2) large parts in the virtual human with the physicality as the real part such as head, arms, and upper body). We report on the implemented results of our virtual humans and experimental results on co-presence and emotional response.

Delivering Meaning through The Five Senses of Color

Seong-Yoon Shin(신성윤),Hyun-Chang Lee(이현창),Kwang-Seong Shin(신광성) 한국정보통신학회 2020 한국정보통신학회 종합학술대회 논문집 Vol.24 No.2