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      • Sarcoma 180 誘發 생쥐의 生存延長에 對한 Cyclophosphamide, Picibanil, 및 Tubercin-3의 單獨 및 倂合投與의 有效成

        鄭泰浩,孫健英 慶北大學校 醫科大學 1981 慶北醫大誌 Vol.22 No.1

        생쥐에 Sarcoma 180을 유발 시키고 각각 그 작용점이 상이한 면역요법제 Tubercin-3와 Picibanil의 단독 요법과 병합요법 그리고 화학요법제 Cyclophosphamide와의 병합사용의 효과를 검토 하였다. Sarcoma 180 유발후의 생쥐의 생존일수의 평균치는 대조군 11.1일 : Tubercin-3투여군 14.8일 : Picibanil 투여군 12.4일 : 그리고 Tubercin-3과 Picibanil의 병합투여군은 8.4일 이었다. Cyclophosphamide 단독투여군의 생존일수는 18.1일이었고 Cyclophosphamide와 Tubercin-3 병합군은 27.4일, Cyclophosphamide와 Picibanil 병합군 22.6일로서 상당히 연장 되었으나 Cyclophosphamide와 두가지 면역요법제를 같이 사용한 동물군의 생존일은 평균 18.7일로서 면역요법제를 사용하지 않은 군과 같았다. This study was carried out to determine the efficacy of combined treatment of cyclophosphamide with Tubercin-3 and Picibanil. One hundred sixty sarcoma 180 bearing mice were divided eight groups of 20 animals each group receiving saline, Tubercin-3, Picibanil, and Cyclophosphamide alone and Cyclophosphamide combined with Tubercin-3, with Picibanil and with both Tubercin-3 and Picibanil respectively. The treatment was initiated 48 horus after tumor cell implantation and repeated three times given once a day with following doses suspended or dissolved in 0.2㎖ of saline at the interval of every other days: 0.5 microgram Tubercin-3 0.1㎎ Picibanil; 3.O㎎ Cyclophophamide; either in alone or in combination. Immunotherapeutic agents were administered by subcutaneously and Cyclophosphamide was given abdominally. The observation of general conditions of animal took place twice a day following treatment and the time of death after tumor implantation was determined. Average survival days in each group of animals were as follows: Control, 11.1 days; Tubercin-3, 14.8 days; Picibanil, 12.4 days; Cyclophosphamide 18.1 days. In combined therapy Cyclophosphamide with Tubercin-3, 27.4 days; Cyclophosphamide with Picibanil, 22.6 day and Cyclophosphamide with both Tubercin-3 and Picibanil 18.7 days. Conclusively, the therapeutic potentiation was reflected to be extended survival in combined treatment of a chemotherapeutics Cyclophosphamide with either one of immunotherapeutics. Tubercin-3 or Picibanil. Combination of Tubercin-3 and Picibanil showed to be antagonistic each other.

      • 油腐加工 중의 기름의 性狀變化 및 油腐貯藏 중의 品質變化

        李應昊,鄭淑鉉,金根淑,金喜衍 釜山水産大學校 1981 釜山水産大學 硏究報告 Vol.21 No.2

        油腐 튀김過程중 튀김用 기름의 性狀變化를 作業時間 經過에 따라 工場規模로 檢討하고 油腐를 4가지 貯藏方法으로 貯藏하여 貯藏期間에 따른 品質 變化를 實驗한 結果는 다음과 같다. 1. 튀김用 기름의 性狀變化에 있어서 산값과 色調는 低溫튀김솥(110±10℃) 및 高溫튀김솥(200±10℃)의 기름의 경우 모든 作業時間에 따라 增加하였으며 특히 低溫튀김솥의 기름의 變化가 더 컸다. 2. 과산화물값과 TBA값은 低溫튀김솥의 기름의 경우 增加하다가 減少하였으며 高溫튀김솥의 경우는 變化가 거의 없었다. 3. 油腐에서 抽出한 기름의 性狀은 高溫튀김솥의 기름의 영향을 크게 받았다. 4. 貯藏方法에 따른 油腐의 品質變化에 있어서 常溫(26±2℃) 貯藏의 경우 包裝하지 않은 것이 包裝한 것보다 貯藏性이 높았으며 脂肪의 酸敗面에서 볼 때 包裝하지 않은 것은 60日程度 貯藏이 가능하였다. 5. 4±2℃에서 貯藏할 경우에는 貯藏 期間에 따른 脂肪의 酸敗는 적었지만 長期貯藏은 困難하였고 -20℃에서 貯藏할 경우에는 貯藏期間에 따른 品質의 變化가 거의 없었으며 貯藏性이 매우 좋았다.

      • 일반향 응고법에 의한 InP 결정 육성

        김호건,정익수 漢陽大學校 基礎科學硏究所 1993 基礎科學論文集 Vol.12 No.-

        일방향 응고법(unidirectional solidification)에 의하여 Ⅲ-V족 화합물 반도체인 InP결정을 육성한 후 결정육성을 위한 기초적 조건을 연구하고 합성된 InP의 전기적 특성을 조사하였다. 길이 50cm의 석영관을 준비하고 석영관의 밑바닥에 인(phosphorus)을 넣고 석영관의 하단으로 부터 15cm윗부분에 인듐금속이 들어있는 석영crucible을 장착하고 석영관 내부의 압력이 10-5torr가 되도록 유지한 후 밀봉하였다. 석영관 밑바닥에 들어있는 P를 450℃의 온도에서 승화시켜 crucible내에 녹아있는 인듐금속에 diffusion되도록 하여 InP조성을 만든 후 시간당 2∼5℃/h의 속도로 서냉시켜 결정을 육성하였다. 육성된 결정에 대하여 X선회절분석과 배면 Laue반사법을 이용하여 InP합성의 여부 및 단결정성을 확인하였고 Van der Pauw법을 이용하여 온도의 변화에 따른 electron mobility, 비저항 등의 전기적 성질을 측정하였다. 각 조건에서 합성된 물질은 InP였으며 주로(111)방향으로 성장하였다. 융액의 냉각속도를 5℃/h이상 비교적 빠르게 했을때는 조성적 과냉각에 의하여 단결정성이 좋지않았으며 2℃/h의 비교적 느린 속도로 결정을 육성하였을때 비교적 양질의 결정을 육성할 수 있었다. XRD분석 및 광학 현미경을 이용한 미세구조 관찰 결과 초기 냉각부분(first freeze portion)인 ingot의 하단에서 후기 냉각부분인 ingot의 상단으로 갈수록 단결정성이 좋은 것으로 밝혀졌다. 전기적 성질을 알아보기 위해서 Hall effet를 측정한 결과 InP결정은 n형 반도체임이 확인되었고 150K∼300K의 온도범위에서 carrier의 농도는 1015∼??이었고 carrier의 이동도는 온도가 증가함에 따라 감소하였으며 그 값은 30X10³∼2×10³㎠/Vsec의 범위였다. Ⅲ-V group compound semiconducter, InP crystal, was prepared by unidirectional solidification method and the fundamental conditions for crystal growth were investigated. Phosphorous (P) powders (99.999% purity) were put into the bottom of a quartz ampule. A quartz crucible charged with Indium metal(99.99% purity) was attached at the upper side in the quartz ampule. The quartz ampule containing quartz crucible was made vacuous under the pressure of 10-5 torr and sealed up. Indium(In) metals in the quartz crucible were melted at 1070℃ and sublimed phosphorous vapors were diffused in Indium melt unidirectionally so that the melt of InP composition was formed from the lower part to the upper part in the quartz crucible. By cooling the InP composition melt, crystal were grown. The grown crystals were characterized by X-ray and microstructure observation under the polarized optical microscope and electrical properties of crystals were measured by Van der Pauw method. The ingots obtained at various cooling rate were identified as InP crystals which had the main growing direction of <111>by the X-ray analysis. The InP single crystals were obtained upper side of the ingot at slow cooling rate of melt. It was found that the InP crystals were n-type semiconducter, that the concentration and mobility of carrier were 1015∼1016/cm-3 and 30X10³∼2×10³㎠/V·sec, respectively.

      • 시뮬레이션 기반의 인적자본지수 향상을 위한 실천전략에 관한 연구

        이건창,민승기,김진성,정남호,권순재 한국기업윤리학회 2003 企業倫理硏究 Vol.7 No.-

        In this study, we focus on defining a human capital, and measuring the human capital index (HCI) which can be used as a proxy of the amount of either human capital or knowledge. For this purpose, we applied a several literature, obtained relevant factors statically from the questionnaire data, and calculated a concrete HCI for each of firms under consideration. The questionnaire data were rigorously collected from 1500 persons of 42 firms in Korean Stock Market. On the basis of the HCI model, we performed HCI simulation. The simulation results showed that proposed approach could be used effectively for analyzing the human capital when the market is rapidly changing.

      • Bi₂Sr₂Ca₁(Cu₁-xFex)₂O8+δ (x=0, 0.003, 0.006, 0.009) 단결정의 전기적 이방성의 어닐링효과에 대한 연구

        설정식,손인호,채건식,최기영 慶南大學校 附設 基礎科學硏究所 1998 硏究論文集 Vol.12 No.-

        The annealing effect of Bi₂Sr₂Ca₁(Cu₁-xFex)₂O8+δ (x=0, 0.003, 0.006, 0.009) single crystal have been studied. The single crystal was grown in air by developed directional solidification method and subsequently annealed for 8 hours at 700℃. The structure of grown singel crystal is measured through X-ray diffraction measurement. We measured resistivity by standard four probe method in the range of temperature from 20 K to 250 K. As the quantity of Fe is increased from x=0 to x=0.009. Tc is decreased from 89 K to 77 K. Tc of annealed samples are smaller than that of as-grown sample.

      • 자생 차(Camellia sinensis L.)의 육묘 방법에 관한 연구

        이용호,이종성,강남대,송근우,강동주,고영옥,정대수 동아대학교 2001 大學院論文集 Vol.26 No.-

        These experiments were conducted to studies on methods raising seedling in Native Tea Trees(Camellia sinensis L.). this experiment was conducted for 2years from 1999 to 2000 in Kyeongnam Provincial Rural Development Administration(R.D.A) The results were summarized as follows: 1. Germination percentage, mature seedling percentage, tiller, leaf number, leaf length and dry weight become higher Cup Pot Φ16cm treatment plot, plant height and leaf area was high some Net Pot Φ15cm treatment plot. 2. The growth of underground and aboveground show a good result all Cup Pot Φ16cm treatment plot. 3. The T/R rate of Cup Pot Φ16cm treatment plot were found 100% and Cup Pot Φ15cm treatment plot were found 114%. 4. The economic gains become higher Cup Pot Φ16cm.

      • Bi₂Sr₂Ca₁Cu₂O8+δ단결정의 전기저항과 전송메카니즘에 대한 연구

        설정식,손인호,채건식,주유환 慶南大學校 附設 基礎科學硏究所 1998 硏究論文集 Vol.12 No.-

        In this work, we have used Aslamasov-Larkin(AL) theory for analyzing the resistive and electrical mechanism of as-grown and 8 hour O₂annealed Bi₂Sr₂Ca₁Cu₂O8+δ samples. Tc is 89K for as-grown sample and 83K for annealed sample. By fluctuation conductivity using AL theory. we have examined that as-grown sample had 3D transition in the wide critical region than for the annealed sample.

      • KCI등재

        계층화된 퍼지 인식도를 이용한 웹 사이트 디자인 시뮬레이션에 관한 연구

        이건창,정남호,조형래 한국경영과학회 2001 韓國經營科學會誌 Vol.26 No.1

        It is well known that the web design is composed of several factors which are interacting with each other. However, the current approach to web design has been focused on modifying specific factors without considering its impact on other factors. In this sense, we propose more holistic approach to the web design by using fuzzy cognitive map. For this purpose, we form an illustrative fuzzy cognitive map for the web design which is based on the literature, and analyze an impact of change in a specific factor on other factors. Especially, to improve the output analyzability, we suggest an advanced version of fuzzy congnitive map called stratified fuzzy cognitive map. After simulating the fuzzy cognitive map for web design, we could conclude that our approach is robust and effective compared to the traditional web design approach.

      • 개선된 Bridgman법으로 성장한 Bi₂Sr₂CaCu₂O_(8+δ) 單結晶의 초전도성

        채건식,손인호,설정식,이수대,김영국,전동성,오재근,강성욱 경남대학교 환경문제연구소 1995 환경연구 Vol.17 No.-

        The Bi₂Sr₂CaCu₂O_(8)+_(δ) single crystals are grown from the melt using a stoichiometric starting composition fer the cautions. The size and thickness of the Bi₂Sr₂CaCu₂O_(8)+_(δ) crystals depends on the cooling rate. The lower the cooling rate, the bigger and thicker the Bi₂Sr₂CaCu₂O_(8)+_(δ) crystals become. Bi₂Sr₂CaCu₂O_(8)+_(δ) X-ray diffraction(XRD) measurements of the single crystals were carried out using the radiation source of Cu Kα . In these Patterns only the (0,0,2n) diffraction appeared. The result indicated that the cleared surface of the single crystal was of the a-b face, and that the single crystal had a single phase without any undergrowth with 7K and 85K phases. In addition, although the figure is not shown, XRD patterns from (006) to (00□) were observed in the range of 2θ=0 to 60 degrees. The characterization of as-grown single crystals have been analyzed by Laue X-ray backsdattering along the c-axis and X-ray precession experiments. The result of magnetic moment vs Tc in 10 Gauss for a crystals were measurements indicated that the samples have a superconducting transition temperature of 85K.

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